• Natural Product Sciences
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• v.10 no.1
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• pp.24-28
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• 2004

The effects of aqueous extract of Artemisia iwayomogi (Compositae) (AIAE) on the mast cell-dependent allergic and inflammatory reactions were investigated. AIAE (0.05 to 1 g/kg) dose-dependently inhibited systemic allergic reaction induced by compound 48/80 in mice. AIAE (0.1 and 1 g/kg) also significantly inhibited local allergic reaction activated by anti-DNP IgE. AIAE (0.001 to 1 mg/ml) dose-dependently inhibited the histamine release from rat peritoneal mast cells (RPMC) activated by compound 48/80. Moreover, AIAE inhibited the secretion of interleukin (IL)-6 in phorbol 12-myristate 13-acetate (PMA) plus calcium ionophore A23187-stimulated human mast cell line (HMC-1) cells. These results provide evidence that AIAE may be beneficial in the treatment of allergic diseases.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.1
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• pp.40-44
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• 2016

Objectives The purpose of this study is to report a Tic-disorder child with allergic rhinitis. Methods The child was suffered from Tic-disorder and the allergic rhinitis, and there were two symptoms of all can last more than a year. sometimes the sniffling, as a sin of allergic rhinitis had caused tic disorder. I thought It was needed to control of both of the symptoms at the same time, so I applied the herbal medicine, CheongKanSoYoSan, for Tic-disorder, and carried out the Aromatherapy and the Laser acupuncture for allergic rhinitis. Results After this treatments, the symptoms of Tic-disorder were disappeared according to improving the symptoms of allergic rhinitis. Conclusions It was suggested that we tried to take care of the patient with Tic-disorder, had to considered the other symptoms that were capable of causing.

• Proceedings of the Korean Society of Applied Pharmacology
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• 1996.04a
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• pp.11-18
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• 1996

We have established an air pouch-type allergic inflammation model in rats [1,2] and a peritoneal eosinophilia model in rats [3]. Employing the two models, chemical mediators and cytokines responsible for the development of inflammation induced by at allergic mechanisms are investigated to clarify the usefulness of the two models for the screening of anti-allergic inflammatory drugs.

• Clinical and Experimental Pediatrics
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• v.51 no.6
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• pp.640-645
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• 2008

Purpose : It is widely known that allergic diseases progress through an allergic march. However, there have not been any recent reports in Korea on how the diseases progress. Methods : Parents who visited one of the Pediatric Allergy Clinics of four university hospitals in Seoul with a child under the age of 6 years during the period from May 1-30, 2006 were asked to complete a questionnaire. Results : A total of 229 parents answered the questionnaire about their children, of which 122 were male and 107 were female. The most common allergic disease before 2 years of age was atopic dermatitis (79%). Meanwhile, in 2- to 4-year age group, allergic rhinitis (38%) and asthma (37%) were predominant. The most common allergic disease in the 4- to 6-year age group was asthma (72%), followed by allergic rhinitis (64%). Seventy-three percent of the children had a family history of allergic disease, most often in the fathers (39%). Among patients with allergic rhinitis, 50% had experienced asthma in their earlier days and 30% had experienced atopic dermatitis. In addition, 57% of the children with asthma had suffered from atopic dermatitis. Parents believed that asthma was the most serious allergic disease. Conclusion : In the present study, allergic disease showed a tendency to march from atopic dermatitis to asthma and then to allergic rhinitis. Early diagnosis and treatment of atopic dermatitis is, therefore, considered important for prevention of the allergic march.

• The Journal of Internal Korean Medicine
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• v.30 no.3
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• pp.534-549
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• 2009

Objectives : To study trends in complementary medical therapy for the allergic rhinitis. This study analyzed research on allergic rhinitis in PubMed. Methods : We searched PubMed related to complementary medical therapy for allergic rhinitis. We analyzed 25 research papers and examined published journals, years countries, and their methods, objectives, results, interventions, participants, periods and instruments of assessment. Results : The method of studies was mostly randomized, double-blind, placebo-controlled trial. There were research papers concerning treatment and prevention with herbal medicine, acupuncture, diet, etc. There were more positive results compared to negative results for treatment and prevention. Most studies were carried out during the winter/spring period. The median for number of participants was 90.54 persons. Diagnostic criteria for enrolment were nasal symptoms, allergic skin test, serum, nasal discharge allergen specific IgE eosinophil, etc. Assessment for outcomes were nasal symptoms, serum, nasal discharge allergen specific IgE eosinophil and Quality of Life Questionnaire. Conclusions : It is necessary to study effects of acupuncture and herb medicines for allergic rhinitis and more in-depth research about trends in complementary medical therapy for allergic rhinitis.

• Child Health Nursing Research
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• v.24 no.1
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• pp.101-108
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• 2018

Purpose: This study aimed to identify the effects of the mother-medical staff partnership on mothers' condition management ability for children with chronic allergic diseases. Methods: A total of 109 Korean mothers caring for a child with a chronic allergic diseases, identified according to the allergic march, such as food allergy, atopic dermatitis, allergic rhinitis, and allergic asthma, were recruited from the pediatric department of a general hospital in Seoul through convenience sampling. Data were collected using structured self-reported questionnaires from August 1, 2017 to October 31, 2017. and analyzed by descriptive statistics and multiple regression using SPSS version 22.0. Results: The Mother-medical staff partnership had a statistically significant effect on mothers' condition management ability for children with chronic allergic diseases (p<.05). Among the general characteristics, satisfaction with nursing services had a statistically significant effect on mothers' condition management ability (p<.05). Conclusion: In conclusion, strategies to support children with chronic allergic diseases, as well as their caregivers, should consider the mother-medical staff partnership as part of a family-centered approach.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.191-203
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• 2007

Objectives : Allergic rhinitis disturbs the quality of life in patients. So, it is important to analyze the quality of life in patients with allergic rhinitis. The aim of this study was to evalute the impact of allergic rhinitis on the quality of life of patients. Methods : A total of 46 patients with allergic rhinitis who visited the Dept. of Oriental Medical Opthalmology & Otolaryngology & Dermatology of Daegu Hanny Oriental Medical Center from July 10th, 2006 to September 10th, 2007 were included in this study. The patients answered the quality of life questionnaire on the scale of one to five. We calculated the frequency and importance. Results : The patients with allergic rhinitis experienced impairment of the quality of life. On the questionnaire, nasal symptoms, practical problems, generalized symptoms were frequently checked. Patients think importance in nasal symptoms, practical problems, generalized symptoms on the questionnaire. Conclusions : Considering the above results, most of patients with allergic rhinitis have problems due to generalized symptoms, practical problems, sleep disturbance, activity limitations, emotional problems, and ocular symtoms including nasal symptoms. Further studies in treatment with Korean medicine are needed.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.95-113
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• 2016

Objectives : The purpose of this review is to introduce the recent advance in allergic rhinitis and to provide help in establishing strategy and selection of drugs for Korean medical treatment of allergic rhinitis. Methods : We searched articles about allergic rhinitis comprehensively in PubMed, CNKI, JStage, KISTI. And in order to reflect clinical situation, we also reviewed some profession's writing for practitioners. Results : This review discussed allergic rhinitis's epidemiology, pathophysiology, diagnosis, treatment, prognosis. We found many standardized clinical practice guideline have been published in this field. And some guideline reflected accumulation of medical evidence on interventions in Korean medicine. It suggested that acupuncture, herbal medicine, herbal patch are useful to prevention and alleviate allergic symptoms. But some interventions have heterogeneity due to each nation's medical background. Conclusions : Acupuncture therapy is now recommended world widely for treating allergic rhinitis. But other interventions of Korean medicine are not well recognized in the same manner. We need more research to identify mechanism and rigorous clinical trials to clarify efficacy and safety of Korean medicine intervention.

• Journal of Life Science
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• v.20 no.6
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• pp.960-963
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• 2010

To evaluate whether chaff vinegar liquor (CVL) has potential in ameliorating allergic symptoms in mice, we tested the anti-allergic activities with a DNFB (dinitrofluorobenzene)-induced allergic mouse model. The DNFB-induced allergic symptoms were reduced by 20% compared to the control by chaff vinegar liquor supplemented with Perilla frutescens var. acuta. Allergic symptoms were examined by measuring the width of epidermis swelling. The hematoxyline & eosin (H&E) staining also revealed that the chaff vinegar liquor dramatically decreased the allergic symptoms in the epidermis of the ear. These results collectively suggest that the chaff vinegar liquor supplemented with P. frutescens var. acuta has potential in ameliorating allergic symptoms, showing that the liquor could be a useful biomaterial(s) for the nutraceutical or cosmetic industries.

• Journal of Environmental Health Sciences
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• v.50 no.4
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• pp.302-310
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• 2024

Background: The prevalence of allergic rhinitis in South Korean adolescents is increasing. Adolescents in South Korea currently use liquid electronic cigarettes more than heated tobacco products. Objectives: The purpose of this study was to assess the association between the use of liquid electronic cigarettes and allergic rhinitis diagnoses among South Korean adolescents. Methods: This study used data from the 17th Korea Youth Risk Behavior Survey in 2021. Out of a total of 59,066 students, data from 18,869 students who had experience with liquid electronic cigarettes were used in the final analyses. Diagnoses of allergic rhinitis by medical doctors were self-reported as outcome variables. Results: For females, when comparing 'daily users' and 'current users' with 'never users', the adjusted odds ratios (ORs) for 'allergic rhinitis' were 2.20 (95% confidence interval (CI), 1.00~4.84) and 1.49 (95% CI, 1.07~2.09), respectively. For males, when comparing 'daily users' and 'current users' with 'never users', the adjusted ORs for 'allergic rhinitis' were 1.42 (95% confidence interval (CI), 0.91~2.22) and 1.41 (95% CI, 1.08~1.84), respectively. Conclusions: The use of liquid electronic cigarettes was statistically significantly associated with increased odds of allergic rhinitis, especially for females. The results of this study will provide a useful scientific basis for establishing public health policy and using the educational data related to the use of liquid electronic cigarettes in the future.