• Journal of the Korean Society of School Health
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• v.28 no.2
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• pp.79-88
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• 2015

The purpose of the study was to investigate mental health and mental health-related factors of adolescents with allergic diseases. Methods: The subjects were 72,060 middle and high school students, the data of whom were extracted from the 2014 Korean Youth' Risk Behavior Web-based Survey. Allergic diseases included asthma, allergic rhinitis and eczema. Mental health was measured by indicators such as perceived stress, depression, and suicidal ideation. To compare the mental health of adolescents who have allergic diseases with that of those who don't, the study used ${\chi}^2-test$ and calculated odds ratio (OR) and 95% confidence interval (CI). In addition, the study used ${\chi}^2-test$and multiple logistic regression, calculating OR and 95% CI, to analyze the association between mental health and allergic diseases and other variables. Results: Of 72,060 adolescents who participated in the study, 51.6% had allergic diseases(asthma 9.2%, allergic rhinitis 32.2%, eczema 23.9%). And 37.1% reported perceived stress, 26.6% depression, and 13.1% suicidal ideation. The adolescents with allergic diseases, compared to the adolescents without allergic diseases, were 1.26 times, 1.28 times, and 1.29 times more likely to experience perceived stress, depression, and suicidal ideation, respectively. The mental health-related factors of adolescents with allergic diseases were school type, sex, socioeconomic status, and academic performance. Conclusion: The adolescents with allergic diseases had poorer mental health than the adolescents without the diseases. Further studies should be done to verify this. And based on the study's findings, school-based intervention programs for mental health of adolescents with allergic diseases need to be developed.

• Korean Institute of Interior Design Journal
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• v.22 no.2
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• pp.140-148
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• 2013

The purpose of this study is to examine the current status of allergic diseases associated with the housing environment and the psychological attitude of residents towards relevant risk factors. This study surveyed 1,200 people. In the first round, 200 participants were questioned through direct survey methods, while 1,000 participants filled out an online survey in the second round. Selected study subjects consisted of allergic diseases known to be closely related to housing environment factors. With advice from medical experts, the analysis included the examination of the prevalence status regarding five types of allergy-related diseases-allergic conjunctivitis, allergic rhinitis, allergic dermatitis, asthma and headache-with the range of disease incidence set within the past ten years. The survey was conducted on all age groups except those nine years old and younger, and the findings are as follows. Allergic diseases were found to be more prevalent among women than men. Residents identified effective methods for the alleviation and treatment of allergic diseases as ventilation, use of environmentally-friendly finishing materials, maintenance of a clean living space through cleaning or washing, and sunlight exposure. Residents' understanding of allergic diseases varied depending on their experience with such diseases and residential characteristics.

• The Journal of Pediatrics of Korean Medicine
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• v.27 no.4
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• pp.77-86
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• 2013

Objectives Allergic purpura is frequent disease in children. The purpose of this study is to analyze traditional Chinese medicine treatments of Allergic purpura in children through traditional Chinese medical journal research. Methods 22 studies were selected based on title keyword "Allergic purpura" "Child" published in CAJ (China Academic Journal). The studies were about clinical effect, herbs, injections, treatments, and nursing in Allergic purpura in children. Results & Conclusions There are so many treatments studied on purpura in children based on CAJ. A Single or combination traditional Chinese medicine treatment is effective in Allergic purpura in children. Therefore, we need to study more about Allergic purpura in children and should make more clinical cases about it.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.20 no.3
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• pp.260-267
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• 2007

Background and Objective : Allergic purpura is a generalized vasculitis characterized by cutaneous purpura, art hritis, abdominal pain, gastrointestinal bleeding and nephritis. However, the pathophysiology of the Allergic purpura remains obscure. Treatment at present is symptomatic and supportive. There is few reports on Allergic purpura treated with oriental medical treatment. Methods : We conducted two patients with Allergic purpura seen at Won-Kwang University Ik-San Oriental Medical Hospital. We treated Allergic purpura by a herbal medicine, acupunture, etc. Conclusions : We suggest that the oriental medical treatment and management have an effect with Allergic purpura which means Podoyug in Oriental medicine.

• Journal of Dairy Science and Biotechnology
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• v.38 no.1
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• pp.19-26
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• 2020

Allergic diseases, including atopic dermatitis, asthma, allergic rhinitis, and food allergies, could be caused by dysbiosis that results in an immune system imbalance. The incidence of allergic diseases has been increasing and they are now one of the most common diseases throughout the world. Recently, probiotics have been suggested as an alternative intervention for the prevention and treatment of allergic diseases. Probiotics are endogenous microflora with functional effects within hosts. They have various clinical and immunological capacities and have recently been considered as a supplement for the treatment and prevention of allergic diseases. Probiotic bacteria modulate immune cells such as Th1, Th2, and regulatory T cells that are correlated with protection against atopic dermatitis, however, safety concerns for the use of probiotics have been raised. Therefore, further research is needed to clarify the efficacy and safety of probiotics in the treatment of allergic diseases.

• Biomolecules & Therapeutics
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• v.19 no.4
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• pp.466-471
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• 2011

Allergic asthma is complex inflammatory airway disorder caused by genetic and environmental factors. Sulfamethoxazole, a sulfonamide, is the cause of drug rash with eosinophilia and systemic symptoms syndrome. Parasites infection also related with eosinophilia and allergic diseases. In the present study, we investigated the modulating effects of parasitic derivative and sulfamethoxazole (SMX) on allergic airway inflammation in the ovalbumin (OVA)-induced murine asthma model. Histopathological changes, cytokine secretion, and total and allergen-specific IgE were investigated. BALB/c mice were treated with Ascaris suum extract or SMX for 4 weeks before sensitized and challenged to ovalbumin. Pre-treatment of Ascaris suum extract decreased allergic inflammation in lung tissue and IL-4, total IgE, and OVA-specific IgE levels in bronchoalveolar lavage fluid. However, pre-treatment of SMX did not show any effects on allergic airway inflammation. These results indicate that parasitic infection has protective effects on allergic asthma, but the sulfamamides may not relate with allergic asthma.

• The Journal of Pediatrics of Korean Medicine
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• v.29 no.4
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• pp.77-89
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• 2015

Objectives The purpose of this study is to analyze Korean clinical studies in Korean medicine and complementary and alternative medicine for allergic rhinitis and to propose for better methods of clinical studies and effective treatments on allergic rhinitis. Methods Electronic researches were performed with NDSL, RISS, KISTI, KISS, OASIS by keyword 'Allergic rhinitis'. Results The treatments used in 36 studies were herbal medicines, acupuncture, pharmacopuncture, moxibustion, cupping, inject medicine to nasal cavity, aroma therapy, ointment, nasal cleansing solution, laser treatment, infra-red therapy, oxygen nebulizer, diet treatment, moxa-pellet treatment, mindfulness meditation and space-spine manipulation techniques. The most common acupoints were LI4 and LI20 (Large Intestine Meridian). The most common methods of assessment is subjective nasal symptoms. All studies using subjective nasal symptoms and quality of life as assessment methods to show valid results on the improvement of allergic rhinitis. Conclusions This study shows that Korean medicine and complementary and alternative medicine on allergic rhinitis are effective. It will be expected to use that various methods for allergic rhinitis and more clinical studies for allergic rhinitis and pediatric patients needed in the future.

• Clinical and Experimental Pediatrics
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• v.59 no.8
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• pp.319-327
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• 2016

Allergic diseases such as asthma, allergic rhinitis, atopic dermatitis, and food allergy, are most common chronic, noncommunicable diseases in childhood. In the past few decades, the prevalence has increased abruptly worldwide. There are 2 possible explanations for the rising prevalence of allergic diseases worldwide, that an increased disease-awareness of physician, patient, or caregivers, and an abrupt exposure to unknown hazards. Unfortunately, the underlying mechanisms remain largely unknown. Despite the continuing efforts worldwide, the etiologies and rising prevalence remain unclear. Thus, it is important to identify and control risk factors in the susceptible individual for the best prevention and management. Genetic susceptibility or environments may be a potential background for the development of allergic disease, however they alone cannot explain the rising prevalence worldwide. There is growing evidence that epigenetic change depends on the gene, environment, and their interactions, may induce a long-lasting altered gene expression and the consequent development of allergic diseases. In epigenetic mechanisms, environmental tobacco smoke (ETS) exposure during critical period (i.e., during pregnancy and early life) are considered as a potential cause of the development of childhood allergic diseases. However, the causal relationship is still unclear. This review aimed to highlight the impact of ETS exposure during the perinatal period on the development of childhood allergic diseases and to propose a future research direction.

• The Journal of Pediatrics of Korean Medicine
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• v.30 no.3
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• pp.31-41
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• 2016

Objectives The purpose of this study is to investigate the characteristics of Ryodoraku Score in the children who visited department of pediatrics, hospital of Korean medicine with allergic rhinitis as the chief complaint. Methods Subjects were 80 children with allergic rhinitis. We calculated the average Ryodoraku Score (RS, ${\mu}A$), and compared the average of each meridian system. And we classified the children by several groups (depending on age, additional allergic disease), and accomplished a comparative analysis. Results 1. The average of Ryodoraku Score in 80 children was $76.36{\pm}22.72$. 2. The figure of H3 (心), H5 (三焦), F1 (脾), F2 (肝), F3 (腎), F4 (膀胱), F5 (三焦), F6 (胃) had significant statistical differences compared to the total average. 3. Comparing the group having only allergic rhinitis to group having allergic rhinitis and other allergic disease, showed significant statistical difference in H2 (心包), H3 (心). 4. Analyzed by age, there's a significant statistical difference in F1 (脾), F4 (膀胱). Conclusion We found that H5 (三焦), F1 (脾), F4 (膀胱) showed significant statistical difference in Ryodoraku Score, and F1 (脾) had the highest relevance. The research indicate meaningful difference depending on age, additional allergic disease.

• Child Health Nursing Research
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• v.18 no.1
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• pp.29-35
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• 2012

Purpose: The purpose of this study was to analyze the prevalence of allergic disease among elementary school students in rural and urban areas. Methods: In this study, 1,513 elementary students (1,163 in urban areas, 350 in rural areas) were surveyed. Data were analyzed using frequency, percentage of allergic symptoms and $X^2$ test was used to identify differences in the prevalence of allergic symptoms between urban and rural area students. The SAS program was used in the data analysis. Results: There were significant differences in the prevalence of allergic disease according to whether there was a family member with a prior history of allergy symptoms. 48.7% of surveyed students (49.4% in urban, 46.3% in rural) had allergic symptoms. Allergic rhinitis was the most frequent allergic symptom in both urban and rural students. Conclusion: These results suggest that there is a need to prevent and manage allergies among elementary students. The family history should be considered an important factor when a program for allergy prevention and management is developed. Interventions are needed in both areas, especially for students with allergic rhinitis.