• 정보기술응용연구
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• 제1권
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• pp.99-127
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• 1999

최근 기업의 생산성 향상을 위한 설계 및 생산 환경의 분산화에 따른 원격지 공동설계의 필요성이 증대되고 있다. 마찬가지로 선박설계 과정도 그 과정이 매우 복잡하고 많은 양의 데이터를 다루고 있는 작업으로서 그 환경이 분산화, 이질화됨에 따라 최근 들어 CSCW (Computer Supported Collaborative Work)의 요구가 증대되고 있다. 본 논문에서는 분산된 선박설계 환경에서의 원격지 공동설계를 지원하기 위한 에이전트기반 선박설계 시스템을 개발하였다. 특히 여기서는 에이전트간의 정보교환 및 지식공유 과정에서 발생하는 의사충돌 문제를 해결하기 위하여 사례기반 추론 기법을 이용하여 이의 해결을 시도하였다. 설계 에이전트, 이들을 중재하는 퍼실리테이터, 충돌 처리기, 그리고 사례기반 시스템의 유기적인 도움을 받아 설계자는 설계과정에서 발생하는 설계 시스템간의 의사충돌 문제에 대한 의사결정을 과거의 유사한 문제해결 사례로부터 효과적으로 처리할 수 있다.

• 대한약침학회지
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• 제19권4호
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• pp.350-358
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• 2016

Objectives: This study was carried out to analyze the single dose toxicity of ShinEumHur (SEH) pharmacopuncture injected into the muscles of Sprague-Dawley rats. Methods: The SEH pharmacopuncture was made in a clean room at the Korean Pharmacopuncture Institute (K-GMP). After the mixing process with sterile distilled water had been completed, the pH was controlled to between 7.0 and 7.5. All experiments were conducted at Biotoxtech, an institution authorized to perform non-clinical studies under the Good Laboratory Practice (GLP) regulations. Sprague-Dawley rats were chosen for the pilot study. Doses of SEH pharmacopuncture, 0.25, 0.5 and 1.0 mL, were administered to the experimental groups, and a dose of normal saline solution, 1.0 mL, was administered to the control group. We examined the survival rate, weights, clinical signs, mean hematology parameters, mean clinical chemistry, necropsy and histopathological findings. This study was conducted under the approval of the Institutional Animal Ethics Committee. Results: No deaths or abnormalities occurred in any of the four groups. No significant changes in weight, hematological parameters or clinical chemistry between the control group and the experimental groups were observed. To check for abnormalities in organs and tissues, we used microscopy to examine representative histological sections of each specified organ; the results showed no significant differences in any of the organs or tissues. Conclusion: The above findings suggest that treatment with SEH pharmacopuncture is relatively safe. Further studies on this subject are needed to yield more concrete evidence.

• Journal of the Korean Wood Science and Technology
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• 제13권2호
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• pp.35-44
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• 1985

The purposes of this study were, first, to investigate retention levels of toxic elements and oxide individual plies for each panel and, second, to examine disproportioning of individual toxic elements Thirty five water gum plywood panels were treated with a copper-chromium-arsenic preservative (CCA) by the soaking process as the treament time were applied. Such individual plies at a distance of 2.5cm, 7.5cm from the edge were assayed for CuO, $CrO_3$, and $As_2O_5$ on the basis of copper, chromium and arsenic content by Atomic Absorption Spectrophotometry. In these experiments, 12mm thickness plywood panels made of water gum, which were selling, were selected for the preservative treatment. Treating solutions were prepared for 10%, dilute solution of copper-chromium-arsenic preservative and then 1, 3, 6, 12 and 24 hours soaking trements in CCA preservative were applied. The results obtained are as follows: 1. The retention of total oxide in the face and back plies (1+7) retained more than the retention of total oxide in the other plies. The total oxide retention for the individual plies except the face and back plies (1+7) was showed in the following orders; cross plies (3+5), cross plies (2+6), core ply (4). 2. The retentions of total oxide increased as the increase of treatment time. The CCA treated plywood retained high levels of total oxide retention in the face and back plies (1+7). 3. All the retentions in the face and back plies (1+7) is over 5Kg/$m^3$, New Zealand Timber Preservation Standards Specification, and after 6 hours, the retentions in the cross plies (3+5) is over 4. The relative penetration of copper, chromium, and arsenic were not affected by the treatment time. The proportion of arsenic decreased in relation to both copper and chromium and the proportion of copper increased in relation to both chromium and arsenic. 5. A disproportioning of copper, chromium occurred with longer distance from edge, and with longer distance from edge the leachability resistance of CCA treated specimens decreased. After 6 hours (soaking time), the proportion of active elements at a distance of 2.5cm from the edge was consistent. And after 24 hours-soaking, the proportion of active elements at a distance of 7.5cm from the edge was consistent.

• 대한자원환경지질학회:학술대회논문집
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• 대한자원환경지질학회 2002년도 제18차 공동학술강연회 자연저감고 지질학 (대한 자원 환경지질학회)
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• pp.81-100
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• 2002

While most of regulatory communities in abroad recognize ' 'natural attenuation " to include degradation, dispersion, dilution, sorption (including precipitation and transformation), and volatilization as governing Processes, regulators prefer "degradation" because this mechanism destroys the contaminant of concern. Unfortunately, true degradation only applies to organic contaminants and short- lived radionuclides, and leaves most metals and long-lived radionuclides. The natural attenuation Processes may reduce the potential risk Posed by site contaminants in three ways: (i)contaminants could be converted to a less toxic form througy destructive processes such as biodegradation or abiotic transformations; (ii) potential exposure levels may be reduced by lowering concentrations (dilution and dispersion); and (iii) contaminant mobility and bioavailability may be reduced by sorption to geomedia. In this review, authors will focus will focul on "sorption" among the natural attenuation processes of hazardous inorganic contaminants including radionuclides. Note though that sorption and transformation processes of inorganic contaminants in the natural setting could be influenced by biotic activities but our discussion would limit only to geochemical reactions involved in the natural attenuation. All of the geochemical reactions have been studied in-depth by numerous researchers for many years to understand "retardation" process of contaminants in the geomedia. The most common approach for estimating retardation is the determination of distrubution coefficiendts ($K_{d}$) of contaminants using parametric or mechanistic models. As typocally used in fate and contaminant transport calculations such as predictive models of the natural attenuation, the $K_{d}$ is defined as the ratio of the contaminant concentration in the surrounding aqueous solution when the system is at equilibrium. Unfortunately, generic or default $K_{d}$ values can result in significant error when used to predict contaminant migration rate and to select a site remediation alternative. Thus, to input the best $K_{d}$ value in the contaminant transport model, it is essential that important geochemical processes affecting the transport should be identified and understood. Precipitation/dissolution and adsorption/desorption are considered the most important geochemical processes affecting the interaction of inorganic and radionuclide contaminants with geomedia at the near and far field, respectively. Most of contaminants to be discussed in this presentation are relatively immobile, i.e., have very high $K_{d}$ values under natural geochemical environments. Unfortunately, the obvious containment in a source area may not be good enough to qualify as monitored natural attenuation site unless owner demonstrate the efficacy if institutional controls that were put in place to protect potential receptors. In this view, natural attenuation as a remedial alternative for some of sites contaminated by hazardous-inorganic components is regulatory and public acceptance issues rather than scientific issue.

• 한국수산과학회지
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• 제16권1호
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• pp.1-7
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• 1983

굴 통조림의 품질을 개선할 목적으로 자숙탈각한 원료 굴을 훈액처리하여 통조림함으로써 재래식 훈연기름담금통조림과 같은 향미를 내면서 녹변색조를 차폐할 수 있어 훈연색조가 고른 제품을 가공하는 방법을 검토하고, 아울러 제품 저장중의 품질안정성에 대하여 검토하였다. 1. 훈액처리굴기름담금통조립 제조조건은 자숙탈각한 굴을 $23.3\%$로 희석한 훈액(Smoke-EZ, Alpha Food Co.,Ltd.)에 30초간 침지한 다음 물기를 빼고, 106-2관 (각 3B관)에 충전하여, $116^{\circ}C$, 65 분간 살균한 후 냉각하는 것이었다. 2. 통조림 육의 색조변화를 보면, 대조제품(기름담금통조림)은 상온저장 20일 째부터 약간 녹변이 생기다가 저장 40일 이후에는 녹변이 확실하게 나타났다. 훈액 또는 훈연처리한 다음 기름담금한 통조림 제품은 녹변색조의 차폐효과가 있었는데, 훈액처리한 제품이 훈연처리한 제품보다 차폐효과가 더욱 좋고, 제품표면이 고른 훈연색조를 나타내었으며, 저장중 품질이 안정하게 유지되었다. 3. 제품의 경도와 toughness는 상온저장 3개월 째부터 약간 떨어졌으나, 탄성 및 응집성은 저장 4개월 째까지 거의 변화가 없었다.

• 정보보호학회논문지
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• 제25권1호
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• pp.181-195
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• 2015

과거 금융권은 고객 및 외부기관과의 연계업무 연속성을 위하여 외부 인터넷망과 내부 업무망을 통합 운영하였다. 그러나 이러한 환경은 악성코드의 유입을 통한 외부 공격 및 정보유출에 대한 위험을 내포하고 있어 금융감독 당국으로부터 보다 근본적인 기술적 관리적 보호대책이 요구되었다. 금융권은 인터넷을 통한 악성코드 감염, 해킹공격 등의 위협으로부터 IT자산을 보호하고, 고객의 개인정보 및 금융거래정보 등 중요정보의 유출을 차단하기 위하여 금융감독당국의 가이드라인에 따라 업무망과 인터넷망을 분리하고, 기존 환경 하에서 정의되었던 보안정책을 망분리 이후 환경에 맞게 재구성하고 있다. 본 연구는 망분리가 적용된 금융회사의 구축사례와 운영현황을 통하여 악성코드 유입 부분에 대한 망분리 정책의 효과를 살펴보고, 모든 경로의 악성코드 유입이 차단되었는지 확인하였다. 연구결과 망분리 이후에도 이동식 저장매체를 통한 악성코드의 감염경로가 완전히 차단되지 않았음을 확인하였다. 이에 따라 망분리 효과를 극대화 할 수 있는 이동식 저장매체의 통제 등의 효율적인 보안정책을 제시하고자 한다.

• 한국토양비료학회지
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• 제30권4호
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• pp.377-383
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• 1997

제약폐기은행잎의 유기물자원화 및 식물생장억제제 개발을 위한 기초자료로 활용코자 은행잎 제약폐기물중에 함유된 식물생육 억제물질을 분리 동정하고 이들물질을 처리하여 무와 벼의 발아 및 초기생육을 검토한 결과는 다음과 같다. 1) 폐기은행잎 조추출물 10% 용액은 무 종자 발아율을 저하시키고 유묘의 생육을 억제하였으나, 1% 농도에서는 뿌리 길이가 약간 짧아졌고, 0.1% 농도는 무처리와 비슷하였다. 벼 발아율은 조추출물 10% 농도에서 31%이상 억제되었다. 2) 지베렐린 $A_3(3.3{\times}10^{-6}M)$와 조추출액(10%)을 벼 유묘와 함께 처리하면 지베렐린 $A_3(3.3{\times}10^{-6}M)$ 단독처리보다 제2엽초장이 짧았다. 3) 조추출액의 산도를 달리한 3종의 액액분리물은 (EtOAc $(pH9)A_1$, EtOAc $(pH3)A_2$, BuOH $A_3$) 모두 1% 농도에서 무 종자의 발아를 완전히 억제하였다. 4) 조추출액을 액액분리, column chromatography, HPLC에 의한 분리정제를 통하여 활성성분을 분리하고, GC/MS, NMR 분석 결과 phenol류인 catechol로 판명되었으며, 폐기은행잎 29kg으로부터 분리한 catechol량은 0.76g이었다.

• The Korean Journal of Physiology
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• 제26권2호
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• pp.113-122
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• 1992

It is well known that chromaffin cells of adrenal medulla secrete catecholamine in response to sympathetic nerve activation and the influx of $Ca^{2+}$ through the voltage dependent $Ca^{2+}$ channels (VDCC) in the cell membrane do a major role in this secretory process. In this study, we explored the effect of divalent cations on VDCC of rat chromaffin cells. Rat (Sprague-Dawley rat, 150-250 gm) chromaffin cells were isolated and cultured. Standard giga seal, whole cell recording techniques were employed to study $Ca^{2+}$ current with external and internal solutions that could effectively isolate VDCC currents $(NMG\;in\;external\;and\;TEA\;and\;Cs^{2+}\;in\;internal\;solution)$. The voltage dependence and the inactivation time course of VDCC in our cells were identical to those of bovine chromaffin cells. A persistent inward current was first activated by depolarizing step pulse from the holding potential (H.P.) of -80 mV to -40 mV, increased to maximum amplitude at around +10 mV, and became smaller with progressively higher depolarizing pulses to reverse at around +60 mV. The inactivation time constant $(\tau)$, fitted from the long duration test potential (2 sec) was $1295.2{\pm}126.8$ msec $(n=20,\;1\;day\;of\;culture,\;mean\;{\pm}S.E.M.)$ and the kinetic parameters were not altered along the culture duration. Nicardipine $(10\;{\mu}M)$ blocked the current almost completely. Among treated divalent cations such as $Cd^{2+},\;Co^{2+},\;Ni^{2+},\;Zn^{2+}\;and\;,Mn^{2+},\;Cd^{2+}$ was the most potent blocker on VDCC. When the depolarizing step pulse from -80 mV to 10 mV was applied, the equilibrium dissociation constant $(K_d)$ of $Cd^{2+}\;was\;39\;{\mu}M,\;K_d\;of\;Co^{2+}\;was\;100\;{\mu}M\;and\;K_d\;of\;Ni^{2+}];was];780{\mu}M.$ The principal findings of this study are as follows. First, the majority of $Ca^{2+}$ channels in rat chromaffin cells are well classified to L-type $Ca^{2+}$ channel in the view of kinetics and pharmacology. Second, all divalent cations tested could block the $Ca^{2+}$ current and the most potent blocker among the tested was $Cd^{2+}$.

• 한국수산과학회지
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• 제14권3호
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• pp.130-138
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• 1981

굴 보일드 통조림의 저장중 품질저하에 영향을 미치는 변색과 영양가의 손실이 전저리와 저장조건을 달리함으로써 억제가 가능한지를 검토하기 위하여 본 연구를 착수하였으며 실험에서 얻은 결과를 요약하면 다음과 같다. 1. 첨가제의 처리는 밀봉직전에 첨가제 용액을 직접 주입하거나 자숙후 첨가제 용액에 침지하는 것이 효과적이었다. 2. 클로로필과 카로티노이드는 산성보다는 알칼리성에서 더 안정했으며, 아미노태질소와 유효성 lysine은 반대현상을 보였다. 3. 자숙굴의 육과 내장에 대한 클로로필의 분배비는 1/55, 카로티노이드의 분배비는 1/68이였으며 5개월 후에는 각각 $1/14\sim1/40$과 $1/4\sim1/20$으로서 카로티노이드가 클로로필에 비하여 훨씬 이행속도가 빨랐다. 4. $Na_{2}EDTA$의 처리는 변색과 영양가 손실의 억제에 상당한 효과가 있었으며, sodium-polyphosphate의 처리는 육의 연화 또는 붕괴를 촉진시키는 역효과를 보였다. 5. 굴통조림 저장중 아미노태질소와 유효성 lysine은 저장초기에 빨리 감소하였으며, 2개월 일 때는 전감소율의 $50\%$에 달하였다. 6. $4^{\circ},\;20^{\circ}C,\;55^{\circ}C$의 각 온도별로 저장한 굴 통조림의 변색과 영양가의 손실은 온도가 다른 요인에 비해 훨씬 큰 영향을 끼쳤으며 온도가 낮을수록 그 손실이 적었다. 7. 관능검사 결과$Na_{2}EDTA$로 처리하여 $4^{\circ}C$에서 저장한 시료가 가장 품질이 우수하였으며, sodium-polyphosphate로 처리하여 $55^{\circ}C$에서 저장한 시료가 품질이 가장 나빴다.

• Strategy21
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• 통권30호
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• pp.236-262
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• 2012

Morgenthau claims that in international relations, there are the economic, political, and military powers that enable a nation to achieve its political and diplomatic goals. This paper explores the possibility of resolving international conflicts with naval power. First, the theoretical and historical perspective, naval power was used as a final resort to force a nation's political or diplomatic objective on an enemy nation when negotiations failed, and this was done through the physical and psychological destruction of the enemy by naval power. But as the use of military power has decreased because of the invention of the nuclear weapon, the existence of a large and capable navy deterrent has become one of the most useful military options among a nation's diplomatic measures. In other words, he focused on the political usefulness of naval power as a deterrent and coercive diplomatic tool for persuading other nations to acquiesce, rather than using naval power and actual military action as a final resort. The reason for this is that compared to army and air force, navy's flexibility, continuity, and the ability to deter are greater. The navy provides excellent accessibility through its wide mobility on the sea, and it has been shown through research that the navy possesses a political usefulness that facilitates the solution of conflicts through presence, naval intervention, and naval blockade. On the other hand, among the factors that could improve the influence of the navy are alliance relations, a reliable and powerful navy, carrots and sticks that it would have to deal with in the case of successful or unsuccessful negotiations, and support from international opinion. On this paper I introduce E.N.Luttwak's naval suasion theory. By the his theory, there are two mode of naval suasion. One is latent naval suasion the other is active suasion. Latent suasion there are deterrent mode and supportive mode. Active naval suasion there are coercive mode and supportive mode. Coercive mode has positive and negative. The limitations of naval suasion have been identified as follows. First, because the objective of the use of naval power is persuading enemy nations, the results are unpredictable. Second, the leaders of all countries possess limited understanding on the complexities of naval power and therefore lack understanding of the usefulness of naval power when choosing options. Third, in case of failure through naval suasion, prestige and reputation of a nation can be damaged. Finally, the following are additional possible research topic. First, a research on the decision making process of choosing naval power as a measure to resolve conflicts is needed. Lastly, research on the size of the navy and types of ships required for efficient naval suasion is needed. Today's world requires cooperative security regime so that middle class navy also requires political use of naval power in solving international conflicts. Therefore, additional research on this topic is needed.