• Title/Summary/Keyword: All-on-Four

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Pharmacological Actions of the Combined Preparations, 'Sahyangsohap-won' and 'Woohwangporyong-hwan' (사향소합원 및 우황포룡환의 약효 연구)

  • Lee, Eun-Bang;Han, Yong-Nam
    • Korean Journal of Pharmacognosy
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    • v.17 no.4
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    • pp.292-301
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    • 1986
  • The combined preparations of the traditional Korean prescriptions, Sahyangsohap-won (A1) and Woohwangporyong-hwan (B1) were evaluated on pharmacological actions in rats and mice, in parallel with the preparations of their modified prescriptions (A2 and B2). The acute toxicities of the four preparations were very low of which $LD_{50}$ values were more than 4g/kg, p.o. and no systematic symptoms were found at the doses. All the preparations showed sedative action by prolongation of sleeping time induced with hexobarbital sodium. The action was more potent in the modified preparations than in the original ones. All the preparations had no anticonvulsant action both in chemoshock seizures induced by pentetrazole and strychnine and in electroshock seizure. In rat fundus preparation, A1 and A2 elicited strong contraction at the concentration of $1{\times}10^{-3}\;g/ml$ in bath, whereas B1 and B2 did neither contraction nor relaxation at the same concentration. The four preparations had no inhibitory effect against acetylcholine induced spasm. In rat intestinal preparation, the four preparations exhibited neither contraction nor relaxation. However, A1 and A2 had antagonistic effect against spasm at the concentration of $1{\times}10^{-3}\;g/ml$. Single administration of each preparation at the dose of 0.24g/kg, p.o. stimulated the secretion of pepsin in rat stomach without inciting the secretion of gastric juice. Their stimulating actions were more marked in B1 and B2 than in A1 and A2, and were more promptly exhibited in the modified preparations (A2 and B2). Accelerating action of bile secretion by single administration of each preparation was found at the dose of 0.24g/kg, p.o. in rats. All the preparations except A2 also stimulated the secretion of bile acid.

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Trends of Upper Jet Streams Characteristics (Intensity, Altitude, Latitude and Longitude) Over the Asia-North Pacific Region Based on Four Reanalysis Datasets (재분석자료들을 활용한 아시아-북태평양 상층제트의 강도(풍속) 및 3차원적 위치 변화 경향)

  • So, Eun-Mi;Suh, Myoung-Seok
    • Atmosphere
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    • v.27 no.1
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    • pp.1-16
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    • 2017
  • In this study, trends of upper jet stream characteristics (intensity, altitude, latitude, and longitude) over the Asia-North Pacific region during the recent 30 (1979~2008) years were analyzed by using four reanalysis datasets (CFSR, ERA-Int., JRA-55, MERRA). We defined the characteristics of upper jet stream as the averages of mass weighted wind speed, mass-flux weighted altitude, latitude and longitude between 400 and 100 hPa. Due to the vertical averaging of jet stream characteristics, our results reveal a weaker spatial variabilities and trends than previous studies. In general, the four reanalysis datasets show similar jet stream properties (intensity, altitude, latitude and longitude) although the magnitude and trends are slightly different among the reanalysis datasets. The altitude of MERRA is slightly higher than that of others for all seasons. The domain averaged intensity shows a weakening trend except for winter and the altitude of jet stream shows an increasing trend for all seasons. Also, the meridional trend of jet core shows a poleward trend for all seasons but it shows a contrasting trend, poleward trend in the continental area but equatorward trend in the Western Pacific region during summer. The zonal trend of jet core is very weak but a relatively strong westward trend in jet core except for spring and winter. The trends of jet stream characteristics found in this study are thermodynamically consistent with the global warming trends observed in the Asia-Pacific region.

The reliability of the nonradiologic measures of thoracic spine rotation in healthy adults

  • Hwang, Donggi;Lee, Ju Hyeong;Moon, Seongyeon;Park, Soon Woo;Woo, Juha;Kim, Cheong
    • Physical Therapy Rehabilitation Science
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    • v.6 no.2
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    • pp.65-70
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    • 2017
  • Objective: The purpose of this study was to examine the intertester reliability and validity of four nonradiologic measurements of thoracic spine rotation in healthy adults. Design: Descriptive laboratory study. Methods: This study was conducted on 20 male and 20 female university students aged between 19 and 26. To measure thoracic rotation, a goniometer, a bubble inclinometer, a dual inclinometer, and a smartphone application-clinometer were used. The measurement was performed twice for each device and the same measurement was performed by two examiners. The measurements were performed in the lumbar locked position. The arm in the direction of rotation was taken back and placed onto the back of the lumbar region. With right and left trunk rotation, the head was rotated together but remained in the center line so that the axial rotation was maintained. Both examiners performed the measuring procedures and directly handled the measuring instrument. All measurement results were recorded by the recorder. Results: The range of motion (ROM) of thoracic rotation in lumbar locked position for all four devices was 47 degrees. The intra-rater reliability estimates ranged from 0.738 to 0.906 (p<0.05). The inter-rater reliability estimates ranged from 0.736 to 0.853 (p<0.05). The goniometer, bubble inclinometer, dual inclinometer, and smartphone clinometer showed high validity (p<0.05). This result indicates that all four devices may be used by the same examiner and by other examiners obtaining follow-up measurement. Conclusions: The use of the goniometer, bubble inclinometer, dual inclinometer, and smartphone clinometer for measurements in the lumbar locked posture are reliable and valid nonradiologic measures of thoracic rotational ROM in healthy adults.

A Review on Marketing Models' Implications to Market Positioning: With a Focus on the Hauser and Shugan Model (마케팅 모형의 포지셔닝 관련 시사점에 대한 고찰: Hauser and Shugan 모형을 중심으로)

  • Won, Jee-Sung
    • Journal of Distribution Science
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    • v.14 no.11
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    • pp.61-73
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    • 2016
  • Purpose - Marketing scholars have developed various types of mathematical models for describing marketing phenomenon, because there is no single model comprehensive enough to incorporate all the relevant marketing phenomena. This study tries to summarize the behavioral foundations and the mathematical derivations of the most widely used marketing models and discusses their strategic implications. This study selected four representative marketing models: multinomial logit(MNL) model, elimination-by-aspects(EBA) model, Hauser and Shugan model and Bass diffusion model. Especially, this study focuses on Hauser and Shugan(1983)'s Defender model and discusses the model's behavioral foundation and its implications. Research design, data, and methodology - Of the four selected model, the multinomial logit model is selected as the basic normative model and the other three models are described as descriptive models in contrast. Starting the discussion from the multinomial logit model, this study explains what important strategic variables are incorporated in each of the four models. The IIA(independence of irrelevant alternatives) axiom and Luce choice model is also discussed in relation to the multinomial logit model. The concept of 'efficient frontier' is discussed in relation to Hauser and Shugan's model. Graphs and tables are used to represent the key implications. No empirical study is included. Results - The analyses of the mathematical marketing models are shown to be very useful in understanding the essence of positioning strategy. The multinomial logit model implies the importance of increasing utility or consumer preference level. The EBA model implies the importance of lowering the inter-brand similarity and dominating the competitors. Hauser and Shugan model implies the importance of considering customer heterogeneity distribution in selecting the target market. Conclusions - It is shown that the concepts of 'efficient frontier' is useful in understanding the effectiveness of positioning strategy. Market positioning can be understood as occupying some place on the efficient frontier. The important strategic implications can be summarized as follows: Always try to increase customer preference by providing what they value, and differentiate from competing alternatives as much as possible. The best positioning strategy is to dominate all the competitors and the worst is to be dominated by the competitors.

Durability assessment of self-compacting concrete with fly ash

  • Deilami, Sahar;Aslani, Farhad;Elchalakani, Mohamed
    • Computers and Concrete
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    • v.19 no.5
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    • pp.489-499
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    • 2017
  • Self-Compacting Concrete (SCC) is a new technology capable to flow without segregation or any addition of energy which leads to efficient construction and cost savings. In this study, the effect of replacing the Ordinary Portland Cement (OPC) with Fly Ash (FA) on the strength, durability of the concrete was investigated experimentally, and carbon footprint and cost were also assessed. Four different replacement FA ratios (0%, 20%, 40% and 60%) were used to create four SCC mixes. Standard test methods were used to determine the workability, strength, and durability of the SCC mixes including resist chloride ion penetration, water permeability, water absorption, and initial surface absorption. The axial cube compressive strength tests were performed on the SCC mixes at 1, 7, 14, 28 and 35 days. Replacing the OPC with FA had a significant positive impact on chloride iron penetration resistance and water absorption but had a considerable negative impact on the compressive strength. The SCC mix with 60% FA had 36.7% and 15.8% enhancement in the resistance to chloride ion penetration and water absorption, respectively. Evaluation of the carbon footprint and the cost of each SCC mixes showed the $CO_2$ emissions mixes 1, 2, 3 and 4 were significantly reduced by increasing the FA content from 0% to 60%. Compared with the control mix, the cost of all mixes increased when the FA content increased, but no significant differences were seen between the estimated costs of all four mixes.

Identification and Characterization of Lactic Acid Bacteria Starters Isolated from the Commercial Drink-Yogurt Products (국내 액상 발효유용 유산균 스타터 미생물의 동정 및 생리적 특성)

  • Jeon, Sang-Rok;Song, Tae-Suk;Kim, Ji-Yoon;Shin, Won-Cheol;Her, Song-Wook;Yoon, Sung-Sik
    • Food Science of Animal Resources
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    • v.27 no.4
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    • pp.509-516
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    • 2007
  • Starters of lactic acid bacteria(LAB) were isolated from the commercial yoghurt products and the four isolates have been studied on their identification and some physiological characteristics. For the purpose of identification, microscopic examination, API test, and 16s rRNA gene sequencing were conducted. Isolate A from a yogurt product of local dairy company A was shown to be Gram-positive rod-shaped bacterium. All strains isolated were turned out to be as Lactobacillus paracasei by using a API 50 CHL kit. In contrast, isolate A was identified as a strain of Lactobacillus helveticus based on the 16S rRNA sequencing data, and L. casei ssp. casei for both B and D and L. paracasei for C. All the isolates survived the simulated gastric juice, pH 2.0 within 3 hours and sharply decreased in viability so that no viable cell was observed after 4.5 hours incubation. In addition, the four isolated strains were almost identical in antibiotic susceptibility to six different kinds of antibiotics including erythromycin ($15\;{\mu}g$), ampicillin ($10\;{\mu}g$), gentamycin ($10\;{\mu}g$), neomycin ($30\;{\mu}g$), but rather resistant to colistin ($10\;{\mu}g$) and streptomycin ($10\;{\mu}g$). It was noteworthy that four isolates were confirmed to produce antibacterial substance against foodborne pathogens of Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli 0157:H7 as test organisms based on the inhibitory zones on an MRS soft agar medium. At presence, the inhibitory factor is unknown so that further studies are required to ascertain the active factor responsible for the inhibitory activities.

Korean New Records of Five Bdelloids including Four Rare Species

  • Song, Min Ok
    • Korean Journal of Environmental Biology
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    • v.33 no.3
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    • pp.283-289
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    • 2015
  • The bdelloids collected from various terrestrial habitats such as mosses, lichens, mushrooms on tree trunks, leaf litter and soil at four different locations in Korea were investigated. Five bdelloids new to Korea were identified: Macrotrachella inermis Donner, 1965, Macrotrachela magna Schulte, 1954, Macrotrachela oblita Donner, 1949, Habrotrocha eremita (Bryce, 1894) and Habrotrocha schultei Donner, 1965. All these rotifers except M. inermis are new to Asia as well. Remarkably, these five Korean new records included four rare species with poorly known distributions. M. magna and H. schultei are recorded outside their type localities for the first time. M. oblita has been reported only from five European countries, and M. inermis has been known from three European countries and Eastern Turkey before the present study. The taxonomy and distribution of each rare bdelloid are discussed here.

CRM Marketing of Shopmasters in Designer Brand Products (디자이너 브랜드 샵마스터의 CRM에 관한 연구)

  • 이승희;이병화
    • Journal of the Korean Society of Clothing and Textiles
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    • v.27 no.2
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    • pp.239-249
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    • 2003
  • The purpose of this research was to investigate influential factors for shopmaster's CRM (Customer Relationship Management) in the designer brand products, and to indicate the future fashion marketing strategies. The questionnaires were distributed to 74 shopmasters of the Designer shop in domestic L. S and H Department stores. Descriptive statistics, factor analysis, and path analysis from Lisrel program were used to analyze the data. The results were as follows; Firstly. for shopmaster's CRM variables, four factors of customer management variables were found and labeled as interest, DB construction, contact opportunity, and materials. Also, four (actors of shopmaster's knowledge regarding apparel materials were found and labeled as professionalism, manner, sense, and persuasion. For service variables, four factors such as precision, variety, rapidity, positiveness, and convenience of shopping were found. Secondly, for the results of hypothesis, all of the independent variables had direct influences on forming the relationship with customers. Therefore, it is concluded that the main elements of Shopmaster's CRM are highly important variables in customer relationship marketing strategy.

A Study of Comparison with the Operating Priority Rules of RMGC on Semi-Automated Container Terminal (반자동화 컨테이너터미널의 RMGC 운영방식 비교 분석)

  • Kim, Chan-Ho;Ha, Tae-Young;Yang, Hong-Suk
    • Journal of the Korean Operations Research and Management Science Society
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    • v.35 no.2
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    • pp.1-17
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    • 2010
  • This paper aims to compare four operating priority rules of RMGC (Rail Mounted Gantry Crane) used in semi-automated container terminal. The four priority rules employed in this paper are FCFS (First-come-first-served), LCFS (Last-come-first-served), TOS (Turn-over-served) and NFS (Nearest-first-served). And to compare the four operating priority rules, this paper analyzed productivity of RMGC and CC (Container Crane), waiting time of YT (Yard Truck) and RT (Road Truck) in container yard, and turnaround time of RT in container terminal of each priority rule by using stevedoring simulation. As a result, NFS was evaluated as the best rule to improve the overall productivity of container terminal in terms of all criteria.

Development of a Group Therapy Program for Social Readjustment of Delinquents Under Probation (보호처분을 받은 비행청소년을 위한 집단치료 프로그램 모형 개발)

  • 정문자;송성자
    • Journal of the Korean Home Economics Association
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    • v.39 no.12
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    • pp.239-251
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    • 2001
  • This study aimed at developing a Social Readjustment Group Therapy Program for delinquents under probation. This program intended to enhance the participants'self-esteem, impose control, daily life habits and relationship with parent. Thirty one male delinquents were chosen from a Probation Center in Seoul, and were divided into one of the four small groups. Group Therapy based on Solution-Focused Brief Therapy Model was given for three hours for ten sessions by four group leaders and four assistants. Results showed meaningful improvement over all of the above target behaviors, especially self-esteem.

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