• Title/Summary/Keyword: All-on-4

검색결과 38,832건 처리시간 0.06초

EFFECTS OF NOVEL DITHIOL MALONATE DERIVATIVES ON LIVER LIPID PEROXIDATION AND ON MICROSOMAL ELECTRON TRANSPORT SYSTEM

  • Park, Keun-Hee;Lee, Jong-Wook
    • Toxicological Research
    • /
    • 제3권2호
    • /
    • pp.97-110
    • /
    • 1987
  • The effects of 5 novel hepatotrophic agents, dithiol malonate derivatives (DMDs; DMD1-DMD5), on the liver microsomal lipid peroxidation induced by carbon tetrachloride $(CCl_4)$ and the correlations with the changes of microsomal electron transport system were investigated. All DMDs were found to inhibit the lipid peroxidation induced by $CCl_4$ in mice and rats as well in vitro liver microsomal system. Therefore, each DMD seemed to have direct mode of action on liver microsomes to inhibit the lipid peroxidation. As an ex vivo study, the induced lipid peroxidation by $CCl_4$ and the changes in electron transport system were determined with liver microsomes obtained from rats chronically treated with DMDs for 7 days. The induced lipid peroxide contents in liver microsomal system were lower in DMD1, DMD2 and DMD3 treated group, but higher in DMD4 and DMD5 group when compared to the control group. Cyt. p.450 contents in the microsomes were decreased by the treatment with DMD1, DMD2 and DMD3, but increased significantly by DMD4 with great extent and by DMD5 with less extent. The cyt. p-450 isozymes induced by treatment of DMD4 and DMD5 were identified as 3-methylcholanthrene (MC) type. The NADPH cyt. -C reductase activities of the microsomes treated with DMD1, DMD2, DMD4 and DMD5 were increased in the range of around 20% to 50%, but decreased with DMD3, All DMDs increased dyt. $-b_5$ content and did not alter NAdH-cyt, $-b_5$ reductase activities in the microsomes. In summary, the 5 novel hepatotrophic agents (DMDs) markedly protected against lipid peroxidation induced by $CCl_4$ in vivo and in vitro possibly through the mechanism of direct action on the liver microsomes. The degree of inhibition produced by DMDs on lipid peroxidation induced by $CCl_4$ seemed to coincide rather with cyt. p-450 contents than with other components of liver microsomal electron transport system including NADPH-cyt, -C reductase.

  • PDF

수종(數種) Composite Resin의 색소침투(色素浸透)에 관(關)한 실험적(實驗的) 연구(硏究) (AN EXPERIMENTAL STUDY ON PENETRATION OF DYE IN COMPOSITE RESIN)

  • 이명종
    • Restorative Dentistry and Endodontics
    • /
    • 제12권1호
    • /
    • pp.155-163
    • /
    • 1986
  • The purpose of this study was to measure penetration of dye stuff (2% Methylene blue, 2% Hematoxylin, 2% crystal violet and 2% safranin-O) on unfilled resin (Lang Dental MFG Co.) Hipol (Boopyung Dental Chemical Co. Macrocomposite resin) Durafill (Kulzer, Co. Microfilled Composite resin) and Heliosit (Vivadent Co. Microfilled Composite resin) The unfilled resin with dough stage was inserted into plastic tuble (5mm in diameter and 4mm in height) with condensation force of 1000 gr, 2000 gr and without condensation force. Hipol mixed on the mixed pad was inserted into the plastic tube by the same method as the unfilled resin. The microfilled resins which were Durafill and Heliosit were polymerized for 60 seconds with the visible light on each surface of the plastic tube which was upper and lower, under condensation force of 1000 gr, 2000 gr and without condensation force. All specimens were stored in the air for 24 hours, then specimens were immersed in the various kind of dye solution for different period of time (1 hour and 24 hours). These dye-treated specimens were polished horizontally until removing 0.5mm of each surface on the emery paper (#1000), and the dye penetration in the polished surface was measured under the digital microscope (Japan Fosuh). Following results were obtained 1. The penetration of dyes was the most excessive in Durafill and was not influenced on the condensation force and the period of immersion time. 2. All dyes were penetrated into Hipol, and Crystal violet was penetrated most excessively in all dyes. 3. The penetration of dye in all resins was not influenced by the period of immersion time and condensation force. 4. There was no evidence of dye penetration in unfilled resin.

  • PDF

The Alignment of Liquid Crystals on the Film Surfaces of Soluble Aromatic Polyimides Bearing t-Butylphenyl and Trimethylsilylphenyl Side Groups

  • Hahm, Suk-Gyu;Jin, Kyeong-Sik;Park, Sam-Dae;Ree, Moon-Hor;Kim, Hyung-Sun;Kwon, Soon-Ki;Kim, Yun-Hi
    • Macromolecular Research
    • /
    • 제17권12호
    • /
    • pp.976-986
    • /
    • 2009
  • With the study goal of firstly elucidating the anisotropic interactions between oriented polymer chain segments and liquid crystal (LC) molecules, and secondly of determining the contributions of the chemical components of the polymer segments to the film surface topography, LC alignment, pretilt, and anchoring energy, we synthesized three dianhydrides, 1,4-bis(4'-t-butylphenyl)pyromellitic dianhydride (BBPD), 1,4-bis(4'-trimethylsilylphenyl)pyromellitic dianhydride(BTPD), and 2,2'-bis(4"-tert-butylphenyl)-4,4',5,5'-biphenyltetracarboxylic dianhydride (BBBPAn), and a series of their organosoluble polyirnides, BBPD-ODA, BBPD-MDA, BBPD-FDA, BTPD-FDA, and BBBPAn-FDA, which contain the diamines 4,4'-oxydianiline (ODA), 4,4'-methylenediamine (MDA), and 4,4'-(hexafluoroisopropylidene)dianiline (FDA). All the polyimides were determined to be positive birefringent polymers, regardless of the chemical components. Although all the rubbed polyimide films exhibited microgrooves which were created by rubbing process, the film surface topography varied depending on the polyimides. In all the rubbed films, the polymer chains were unidirectionally oriented along the rubbing direction. However, the degree of in-plane birefringence in the rubbed film varied depending on the polyimides. The rubbing-aligned polymer chains in the polyimide films effectively induced the alignment of nematic LCs along their orientation directors by anisotropic interactions between the preferentially oriented polymer chain segments and the LCs. The azimuthal and polar anchoring energies of the LCs ranged from $0.45{\times}10^{-4}\;-\;1.37{\times}10^{-4}\;J/m^2$ and from $0.86{\times}10^{-5}\;-\;4.26{\times}10^{-5}\;J/m^2$, respectively, depending on the polyimides. The pretilt angles of the LCs were in the range $0.10-0.62^{\circ}$. In summary, the soluble aromatic polyimides reported here are promising LC alignment layer candidates for the production of advanced LC display devices.

An Efficient FPGA based Real-Time Implementation Shunt Active Power Filter for Current Harmonic Elimination and Reactive Power Compensation

  • Charles, S.;Vivekanandan, C.
    • Journal of Electrical Engineering and Technology
    • /
    • 제10권4호
    • /
    • pp.1655-1666
    • /
    • 2015
  • This paper proposes a new approach of Field Programmable Gate Array (FPGA) controlled digital implementation of shunt active power filter (SAPF) under steady state and dynamic operations. Typical implementations of SAPF uses microprocessor and digital signal processor (DSP) but it limited for complex algorithm structure, absence of feedback loop delays and their cost can be exceed the benefit they bring. In this paper, the hardware resources of an FPGA are configured and implemented in order to overcome conventional microcontroller or digital signal processor implementations. This proposed FPGA digital implementation scheme has very less execution time and boosts the overall performance of the system. The FPGA controller integrates the entire control algorithm of an SAPF, including synchronous reference frame transformation, phase locked loop, low pass filter and inverter current controller etc. All these required algorithms are implemented with a single all-on chip FPGA module which provides freedom to reconfigure for any other applications. The entire algorithm is coded, processed and simulated using Xilinx 12.1 ISE suite to estimate the advantages of the proposed system. The coded algorithm is also defused on a single all-on-chip Xilinx Spartan 3A DSP-XC3SD1800 laboratory prototype and experimental results thus obtained match with simulated counterparts under the dynamic state and steady state operating conditions.

A new description of the fractal dimension of particle aggregates in liquid medium

  • Xing, Jun;Ding, Shiqiang;Liu, Zhengning;Xu, Jirun
    • 한국입자에어로졸학회지
    • /
    • 제11권4호
    • /
    • pp.99-105
    • /
    • 2015
  • The possible existence forms of particle aggregates in liquid medium are classified into four different types according to their morphological characteristics, including the single particles that are separated from each other, the linear aggregates in which all component particles are located in a line, the planar aggregates where all particles are arranged on a plane, and the volumetric aggregates where all particles forms a three-dimensional space. These particle aggregates with different space morphologies have different fractal dimensions and different influence on the rheological phenomena of the solid-liquid system. The effects of various aggregates on the suspension viscosity are analyzed and related with the particle concentration, and then a mathematical model is presented to determine the fractal dimensions of various aggregates by measuring the apparent viscosity of the solid-liquid system. In the model, the viscous fractal dimension is developed as a new concept, the fractal dimensions of different aggregates can be obtained separately and then the relative components of various aggregates experimentally analyzed.

식용 버섯류의 무기물 함량 (Studies on the Mineral Content of Edible Mushrooms)

  • 허윤행;김옥경
    • 한국환경보건학회지
    • /
    • 제17권1호
    • /
    • pp.129-135
    • /
    • 1991
  • To investigate on the trace element content of twelve edible mushrooms and Aloe arborescens, i. e., Lentinus edodes, Ganoderma lucidum (culturing in wood and soil), Tricholoma matsutake, Agaricus bisporus, Cyrophora esculenta, Auricularia auricula-Jude (produced in Korea and China), Sarcodon asparatus, Pleurotus ostreatus, Coriolus versicolor, Smilax rotundifolia and Aloe arborescerts were analyzed by Atomic absorption spectrometer. The obtained results were summerized as follows: 1. Potassium, sodium, magnesium and iron content for the most part samples were in large quantities, especially phosphorus content of those was highest ammount for the all samples. 2. Sodium content was much ammount in the Lentinus edodes (39mg) and Ganoderma lucidurn (20 mg), Culturing in wood and soil, while potassium was very high ammount in the Aloe arborescens and other samples. Mush ammount of magnesium as compared with others was Lentinus edodes (144mg), Ganoderma lucidurn (128mg), Aloe arborescerts (50mg) and pleurotus ostreatus (60mg). Phosphorus content of Ganoderma lucidurn, Lentinus edodes, Gyrophora esculenta, Auricularia polytricha and Agaricus bisporus was much ammount while iron content of all samples equality higher ammount. Sodium content of Aloe arborescens was not analyzed out for almost all, its potassium (82mg), magnesium (50mg) and iron (18rng) content comparatively higher quentity than others minerals and phosphorus volume (4.9mg) as compared with others, was conspicuously lower detect. 4. Cadimium and lead content of harmful metal element were detected on trace quentity for the most part samples 5. Organic acids of samples i.e., Legtinus edodes, Agaricus bisporus, Pleurotus ostreatus and Ganoderma lucidum were Citrate, Malate, Fumalate, Succinate, Oxalate, Acetate, Lactate, and Tartarate and Citrate, Malate and Fumarate contents were higher amount remarkbly than other organic acids. Tartarate content was trace amount.

  • PDF

EFFECT OF FEEDING CLOMIPHENE CITRATE ON CARCASS COMPOSITION OF BROILER

  • Ali, M.A.;Shingari, B.K.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • 제2권1호
    • /
    • pp.17-21
    • /
    • 1989
  • Four seasonal trials were conducted to study the effect of feeding clomiphene citrate on carcass composition of broilers. It was fed at 5, 10, 15 mg levels per kg feed for a period of two weeks, 3-4 weeks ($S_1$), 4-5 weeks ($S_2$) and 5-6 weeks ($S_3$) of age. Total carcasses were analysed for moisture, ether extract and protein. Clomiphene citrate significantly decreased the moisture with concomitant increase in ether extract content of the carcasses at all the ages and seasons. Carcass protein was significantly decreased at all the ages and seasons. The responses in the different level of clomiphene citrate is dose dependent. The carcass moisture decreased with age while protein and ether extract contents increased in all seasons. The females had more ether extract and less moisture contents than male. The carcass ether extract was higher in summer and rainy seasons followed by spring and winter seasons, and the differences were significant. A concomitant significant decrease of carcass moisture was observed. The effect of seasons on carcass protein varied at different ages but there appeared to be a trend towards decreasing carcass protein in summer and rainy seasons than winter and spring seasons.

Effects of Microbial Transglutaminase on Physicochemical, Microbial and Sensorial Properties of Kefir Produced by Using Mixture Cow's and Soymilk

  • Temiz, Hasan;Dagyildiz, Kubra
    • 한국축산식품학회지
    • /
    • 제37권4호
    • /
    • pp.606-616
    • /
    • 2017
  • The objective of this research was to investigate the effects microbial transglutaminase (mTGs) on the physicochemical, microbial and sensory properties of kefir produced by using mix cow and soymilk. Kefir batches were prepared using 0, 0.5, 1 and 1.5 Units m-TGs for per g of milk protein. Adding m-TGs to milk caused an increase in the pH and viscosity and caused a decrease in titratable acidity and syneresis in the kefir samples. Total bacteria, lactobacilli and streptococci counts decreased, while yeast counts increased in all the samples during storage. Alcohols and acids compounds have increased in all the samples except in the control samples, while carbonyl compounds have decreased in all the samples during storage (1-30 d). The differences in the percentage of alcohols, carbonyl compounds and acids in total volatiles on the 1st and the 30th d of storage were observed at 8.47-23.52%, 6.94-25.46% and 59.64-63.69%, respectively. The consumer evaluation of the kefir samples showed that greater levels of acceptability were found for samples which had been added 1.5 U m-TGs for per g of milk protein.

치과공포가 치과이용행태 및 치료요구도에 미치는 영향 (Effect of dental fear on dental use behavior and treatment need degree)

  • 전성희;정명희
    • 한국치위생학회지
    • /
    • 제7권3호
    • /
    • pp.329-342
    • /
    • 2007
  • This study was conducted in order to know whether DFS questionnaire which can measure dental fear is suitable for dental fear measuring method and to know effect of dental fear on dental use behavior and treatment need degree. This survey was conducted from May 1, 2007 to May 31, 2007. A total of 281 surveys eligible among all the collected surveys were used in the analysis. Collected data were analyzed by using SPSS 12.0. The obtained results were as follows: 1. Based on the reliability analysis, we concluded that the questionnaire of dental fear was reliable, and the Cronbach' s alpha coefficients of the all subscales were more than 0.6. 2. Among the dental fear of 3 factors, treatment fear cause stimulation factor was higher than the others. Most of all, following two situations(when preparation was made and when people hear dental instrument operating sound) are the highest in the treatment fear. And women are higher than men in every item. 3. In the Dental treatment need degree caused by dental fear degree, high fear group was $4.76{\pm}1.954(M{\pm}SD)$ which was higher than that of low fear group.(low fear group was $4.07{\pm}2.184(M{\pm}SD)$. In conclusion, dental fear and dental treatment need degree are related each other.

  • PDF

자동차화재 실태 분석 (Analysis of Actual State of Motor Vehicle Fires in Korea)

  • 이의평
    • 한국화재소방학회논문지
    • /
    • 제25권2호
    • /
    • pp.47-59
    • /
    • 2011
  • 화재통계연보와 국가화재정보시스템의 자료를 기초로 자동차화재 실태를 분석한 결과 아래와 같은 내용을 파악할 수 있었다. 자동차화재는 매일 16건 이상 발생하여 0.5명 이상의 사상자와 5천만원 이상의 직접적인 재산손실이 발생하고 있다. 자동차화재의 원인은 기계적 요인이 가장 많고 이어서 전기적 요인과 방화 순이며, 전체화재 중 방화의 비율은 7.39%이지만 차량화재 중 방화화재의 비율은 13.79%이다. 연간 자동차화재 100건당 사망자는 평균 0.9명이며 부상자는 평균 2.4명이다. 전체 자동차화재 중 고속도로에서 발생하는 화재건수가 12.55%를 차지하고 있음에도 고속도로 자동차화재의 사망자는 16.12%, 부상자는 21.05%, 재산피해는 20.65%를 차지하고 있다.