• Journal of mucopolysaccharidosis and rare diseases
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• 제4권1호
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• pp.1-6
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• 2018

Lysosomal storage disorders are a group of rare inherited metabolic disorders with protean manifestations and variable severity ranging from attenuated forms to severe ones. It is necessary to diagnose and manage these disorders timely before irreversible damage occurs. Prior to the era of enzyme replacement therapy and newer therapeutics, only treatment option available was palliative care. Over the past two decades, extensive research in the lysosomal storage disorders has led to substantial expansion of our understanding about them. This mini review focusses on the spectrum, challenges faced in the diagnosis and therapy and remedial actions taken so far in lysosomal storage disorders in resource constrained country like India.

• Journal of Chest Surgery
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• 제19권4호
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• pp.699-706
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• 1986

We have experienced 5 cases of Pectus excavatum corrected by Ravitch method without use of K-wire or metal bar from Jan. 1985 to Apr. 1986. All cases were male. The symmetric depression was in 4 cases, asymmetric one was in one case. The chief complaints were dyspnea on exertion, frequent U.R.I. and inferiority. The flail chest was developed in all cases, but it was insignificant in all cases except one who needed assist ventilation. Mediastinitis was developed in one case one week postoperatively but well managed with drainage. A distance from the posterior surface of sternum to the anterior surface of vertebral body was estimated preoperatively and postoperatively. Postoperative result was evaluated as the change of distance postoperatively. The change was 1.5cm minimally to 3.5cm maximally. Late results were "Excellent" in 3 cases and "Good" in 2 cases.uot; in 2 cases.

• Kyungpook Mathematical Journal
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• 제48권4호
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• pp.529-543
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• 2008

It is shown that every almost linear mapping h : $A{\rightarrow}B$ of a unital PoissonC*-algebra A to a unital Poisson C*-algebra B is a Poisson C*-algebra homomorph when $h(2^nuy)\;=\;h(2^nu)h(y)$ or $h(3^nuy)\;=\;h(3^nu)h(y)$ for all $y\;\in\;A$, all unitary elements $u\;\in\;A$ and n = 0, 1, 2,$\codts$, and that every almost linear almost multiplicative mapping h : $A{\rightarrow}B$ is a Poisson C*-algebra homomorphism when h(2x) = 2h(x) or h(3x) = 3h(x for all $x\;\in\;A$. Here the numbers 2, 3 depend on the functional equations given in the almost linear mappings or in the almost linear almost multiplicative mappings. We prove the Cauchy-Rassias stability of Poisson C*-algebra homomorphisms in unital Poisson C*-algebras, and of homomorphisms in Poisson Banach modules over a unital Poisson C*-algebra.

• Journal of Electrical Engineering and Technology
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• 제8권4호
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• pp.744-751
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• 2013

In this paper, Secant method is proposed to solve multi area economic dispatch (MAED) problem. Generator limits of all generators in each area are calculated at given area power demands plus export (or import) using secant method and the generator limits of all generators are modified as modified generator limits. Central economic dispatch (CED) problem is used to determine the output powers of all generators. Here, Secant method is applied to solve the CED problem. The proposed approach has been tested on two-area (two generators in each area) system and four-area (four generators in each area) system. It is observed from various cases that the proposed approach provides optimally best solution in terms of cost with tie line loss with less computational burden.

• Genomics & Informatics
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• 제20권1호
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• pp.5.1-5.10
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• 2022

Non-syndromic hearing loss (NSHL) is a common hereditary disorder. Both clinical and genetic heterogeneity has created many obstacles to understanding the causes of NSHL. The present study has attempted to ravel the genetic aetiology in NSHL progression and to screen out potential target genes using computational approaches. The reported NSHL target genes (2009-2020) have been studied by analyzing different biochemical and signaling pathways, interpretation of their functional association network, and discovery of important regulatory interactions with three previously established miRNAs in the human inner ear as well as in NSHL such as miR-183, miR-182, and miR-96. This study has identified SMAD4 and SNAI2 as the most putative target genes of NSHL. But pathogenic and deleterious non-synonymous single nucleotide polymorphisms discovered within SMAD4 is anticipated to have an impact on NSHL progression. Additionally, the identified deleterious variants in the functional domains of SMAD4 added a supportive clue for further study. Thus, the identified deleterious variant i.e., rs377767367 (G491V) in SMAD4 needs further clinical validation. The present outcomes would provide insights into the genetics of NSHL progression.

• 한방안이비인후피부과학회지
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• 제36권4호
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• pp.70-87
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• 2023

Objectives : The purpose of this research is to review the efficacy and safety of taping therapy for facial palsy. Methods : Two foreign databases(Pubmed, CNKI) and one domestic database(OASIS) were used to search, and papers retrieved from the starting point of literature provision in each database until June 19, 2023 were included in the study. All studies in which other treatments were performed as a treatment intervention along with taping therapy were included, but cases where taping therapy was a comparative intervention were excluded. Results : 18 studies were selected. 14 studies were two-arm randomized controlled trials(RCT), and 4 studies were case reports. There was improvement in facial palsy in all 4 case reports, and in all 14 RCTs, the treatment effect in the observation group was significantly higher than in the control group. Conclusions : Taping therapy can be an effective and safe treatment method for facial palsy. However, the risk of bias in the selected studies was high, and there were many cases in which multiple interventions other than taping therapy were applied simultaneously. Therefore, well-designed studies with high quality are needed in the future.

• 한국광학회지
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• 제23권4호
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• pp.143-146
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• 2012

본 논문에서는 반도체 광 증폭기(Semiconductor Optical Amplifier)의 교차 진폭 변조 현상을 이용하여 광 컴퓨팅이나 광통신에서 데이터의 패킷 교환, 데이터 리셋 혹은 추가나 제거에 필수적인 전광 데이터 추출을 시뮬레이션하고 실험적으로 구현하였다. 전광 데이터 추출의 실험적 시뮬레이션에는 상용 프로그램인 VPI Tool을 사용하였으며 기본적으로 두 개의 반도체 광 증폭기(SOA)를 사용하여 AND 논리를 구성한 후 이를 이용하여 데이터를 추출하였다. 또한 높은 집적성과 효율로 고속으로 연산할 수 있는 가능성을 확인하였다.

• 대한치과보철학회지
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• 제35권4호
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• pp.719-741
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• 1997

This study was undertaken to compare by Atomic Force Microscope the effects of various finishing and polishing instruments on surface roughness of filling and veneering composite resins. Seven composite resins were studied : Silux Plus (3M Dental Products, U.S.A.), Charisma (Heraeus Kulzer, Germany), Prisma THP (L.D.Caulk, Dentsply, U.S.A.), Photoclearfil (Kuraray, Japan), Cesead (Kuraray, Japan), Thermoresin LC (GC, Japan), Artglass (Heraeus Kulzer, Germany). Samples were placed and polymerized in holes (2mm thick and 8.5mm in diameter) machined in Teflon mold under glass plate, ensuring excess of material and moulded to shape with polyester matrix strip. Except control group (Polyester matrix strip), all experimental groups were finished and polishied under manufacturer's instructions. The finishing and polishing procedure were : carbide bur (E.T carbide set 4159, Komet, Germany), diamond bur (composite resin polishing bur set, GC, Japan), aluminum-oxide disc (Sof-Lex Pop-On, 3M Dental Products, U.S.A.), diamond-particle disc (Dia-Finish, Renfert Germany), white stone bur & rubber point( composite finishing kit, EDENTA, Swiss), respectively. Each specimens were evaluated for the surface roughness with Atomic Force Microscope (AutoProbe CP, Park Scientific Instruments, U.S.A.) under contact mode and constant height mode. The results as follows : 1. Except Thermoresin LC, all experimental composite resin groups showed more rougher than control group after finishing and polishing(p<0.1). 2. A surface as smooth as control group was obtained by $Al_{2}O_{3}$ disc all filling composite resin groups except Charisma and all veneering composite resin groups except Thermoresin LC(p<0.05). 3. In case of Thermoresin LC, there were no statistically significant differences before and after finishing and polishing(p>0.1). 4. Carbide bur, diamond bur showed rough surfaces in all composite resin groups, so these were inappropriate for the final polishing instruments.

• 한방안이비인후피부과학회지
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• 제3권1호
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• pp.41-57
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• 1990

In order to investigate the effects of Hwang Keum Jag Yag Tang (HJT) water extract on the plasma cortisol concentration in the rabbit and on the analgesic effect in the mouse were administered. The results were summarized as follow: 1. Intravenous administration of HJT water extract at the dose of 0.2ml/kg remarkably increased plasma cortisol concentration after two hour. 2. Intravenous administration of HJT water extract at the dose of 0.4ml/kg significantly increased plasma cortisol concentration after one hour. 3. Intravenous administration of HJT water extract at the dose of 0.2ml/kg, all the experimental period, significantly increased plasma sodium concentration. 4. Intravenous administration of HJT water extract at the dose of 0.4m1/kg significantly decreased plasma potassium concentration. 5. Intravenous administration of HJT water extract at the dose of 0.2ml/kg and 0.4ml/kg, all the experimental period, significantly decreased plasma calcium concentration. 6. The analgesic effect of HJT water extract showed inhibitory effect more than at 0.1ml/20g. According to the results, Hwang Keum Jag Yag Tang water extract remarkably increased plasma cortisol concentration and showed analgesic effect.

• 농촌계획
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• 제21권4호
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• pp.115-125
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• 2015

This study is to analyze the preference of experiential activities and behavioral intention on rural tourism, with special focus on parents group of elementary students. The result can be utilized as basic data for demanding aspect of rural experiencing tourism. Two-step questionnaire survey was conducted, during May to July, 2915. Sample group was selected at 4 elementary school in Daegu city. 347 valid responses were analyzed with SPSS. Major results are as follows. Firstly, suggested model for 23 experiential activities in 7 types, were verified as valid by verifying factor analysis. Factor 1 was verified and named as 'Rual Life Experience', Factor 2 was verified and named as 'Health/Healing Experience', Factor 3, as 'Agricultural Product Experience', Factor 4, as 'Eco-Cultural Experience', Factor 5, as 'Leisure/Sports Experience', Factor 6, as 'Traditional Wellbeing Food Experience', and Factor 7, as 'Traditional Culture Experience'. All 7 factors explained 75.39% of total variance. Secondly, mean score of preference by each activity showed high in 'Health-care experience', 'Traditional food experience' and comparatively low in 'Collecting experience', 'Agricultural experience'. Thirdly, all 7 types(factors) of experience showed significant affecting relation to satisfaction, intention to participation and recommendation. Specially, 'Eco-Cultural Experience' and 'Rural Life Experience' showed high affecting relation. This could be the characteristics of parents group of elementary students.