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The Effect of Oral Administered Medium Chain Triglyceride Diet on the Serum Lipids and Enzyme Activities of Rats (MCT를 경구투여(經口投與)한 흰쥐의 혈중지질(血中脂質) 및 효소활성(酵素活性)에 미치는 영향(影響))

  • Cho, Chung-Soon;Jeong, Seung-Tai
    • Journal of the Korean Applied Science and Technology
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    • v.5 no.1
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    • pp.31-40
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    • 1988
  • The purpous of the study was to find an effect of oral administered medium chain triglyceride(MCT) diet on the serum and enzyme activities of Spraque-Dawly rats when they were oral fed with MCT, soybean oil and palm oil. The result was as follow. 1) The body weight gains in MCT diet group was lower than that of the all experimental group. 2) Total cholesterol levels in serum and liver of MCT diet group were very lower than that of the all experimental groups. 3) HDL-cholesterol level of MCT diet group was higher than that of the all experimental group except normal group and VLDL, LDL-cholesterol levels was very higher. 4) TG and PL levels of MCT diet group higher than that of the control group. 5) The activities of GOT with soybean oil diet group and of GPT with MCT diet group were lower than that of the all experimental group. 6) HDL-levels in the serum lipoprotein of MCT diet group was increased and LDL levels was decreased.

An Epidemiological Surrey on Cholera in Pusan City 1970 (1970년 부산에서 유행한 콜레라에 대한 역학적 조사)

  • Kim, Don-Kyoun;Kim, Joon-Yun;Suh, Young-Tae
    • Journal of Preventive Medicine and Public Health
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    • v.3 no.1
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    • pp.31-36
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    • 1970
  • An epidemiological survey on cholera was made toward the 291 cases admitted in Pusan National University Hospital. The results were as follows. 1. The most predominant age groups among all cholera patients were from 30 to 39(21.3%). 2. 74.9% of all cases got under the educational background of primary school and 69.4% of all cases occurred at the low income group. 3. Daily average numbers of patient were 6.2 and maximum numbers wore 15, August 19, 1970. 4. Among the food eaten prior to onset, drinking water was the most predominant with 16.2% and next, food and noodle groups were 14.8% and 10.3% respectively. 5. Regarding incubation period, it was found that 'within 48 hours' was 83.5%. 6. Patients occurred mainly in Suh Ku area with 105(36.1%) of all cases. 7. Carrier rates among family members were 1.78%. 8. Carrier rates among residents of epidemic area were 0.12%.

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Evaluation of Anticancer Activity of Curcumin Analogues Bearing a Heterocyclic Nucleus

  • Ahsan, Mohamed Jawed
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.4
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    • pp.1739-1744
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    • 2016
  • We report herein an in vitro anticancer evaluation of a series of seven curcumin analogues (3a-g). The National Cancer Institute (NCI US) Protocol was followed and all the compounds were evaluated for their anticancer activity on nine different panels (leukemia, non small cell lung cancer, colon cancer, CNS cancer, melanoma, ovarian cancer, renal cancer, prostate cancer and breast cancer) represented by 60 NCI human cancer cell lines. All the compounds showed significant anticancer activity in one dose assay (drug concentration $10{\mu}M$) and hence were evaluated further in five dose assays (0.01, 0.1, 1, 10 and $100{\mu}M$) and three dose related parameters $GI_{50}$, TGI and $LC_{50}$ were calculated for each (3a-g) in micro molar drug concentrations (${\mu}M$). The compound 3d (NSC 757927) showed maximum mean percent growth inhibition (PGI) of 112.2%, while compound 3g (NSC 763374) showed less mean PGI of 40.1% in the one dose assay. The maximum anticancer activity was observed with the SR (leukemia) cell line with a $GI_{50}$ of $0.03{\mu}M$. The calculated average sensitivity of all cell lines of a particular subpanel toward the test agent showed that all the curcumin analogues showed maximum activity on leukemia cell lines with $GI_{50}$ values between 0.23 and $2.67{\mu}M$.

Roll Forming Analysis for All-in-one Cable Tray (일체형 케이블 트레이의 롤포밍 성형해석에 관한 연구)

  • Han, Myung-Chul;Sung, Chang-Min;Kim, Jung-Kwan;Gwon, Yu-Hong
    • Journal of the Korean Society of Manufacturing Process Engineers
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    • v.17 no.4
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    • pp.143-149
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    • 2018
  • A cable tray is a fixture to support and protect electrical and communication cables. In this study, a roll-forming analysis is conducted to produce an all-in-one cable tray. The number of process stands is calculated using an empirical formula. By applying bending methods to the design of the roll flower pattern, the final process stands and forming angles are determined. The shape and stress variations in the cable tray are modeled and observed by roll forming analysis using LS-DYNA Software. The width of the side rail and the maximum stress on all stands does not exceed the reference values. The forming machine and rolls are manufactured based on the results of the roll forming analysis. In addition, all-in-one cable trays satisfy the National Electrical Manufacturers Association standards when they are manufactured according to this design.

A study on easy-to-use drug formulation for emergency medical technicians (응급구조사들이 사용하는 약물의 제형 개발에 관한 연구)

  • Kim, Hoon;Kim, Chul-Tae
    • The Korean Journal of Emergency Medical Services
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    • v.24 no.2
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    • pp.89-97
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    • 2020
  • Purpose: In this study we aimed to manufacture and evaluate an oral disintegrating film containing ibuprofen. Methods: Optimal oral ventilation was manufactured using ibuprofen 3g, polyvinyl alcohol #500 4.2g, HPMC K 100M 1.6g, glycerol 4g, TWEEN #20 0.3g, PEG #20 0.3g, citric acid 0.5g, sucralose 0.1g, ethamol 10mL, and distilled water 30mL. Results: Film mass ranged from 110 to 130mg in all prescriptions, showing general uniformity while the water content ranged from 6 to 12%. Measurement of ibuprofen content in all manufactured film solutions averaged 100.12% (98.0-102.0%). The elution test predicted the time taken from the body and the film agent of all prescriptions was released 100% within 5 minutes to confirm the rapid elution. Conclusion: Based on the results of all test, prescription E was proved to be the most suitable.

A Study on the process of the rancidity of frying oil (튀김과정에서의 변성유생성에 관한 연구)

  • 고영수
    • Journal of the Korean Home Economics Association
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    • v.24 no.4
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    • pp.75-84
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    • 1986
  • The followings are the results of the study on decomposition of oil during the process of frying hot-dogs with soybean oil. First, the oil was heated repeatedly for six days, four hours two session per day. Then the oil was observed when heated under identical condition except for the exclusion of the frying ingredients. And the oil itself was heated constantly for a period of 48 hours. 1. The AV and Carbonyl Value of all frying oils increased with each use (but the oil in which frying ingredients with all other oils) 2. All frying oils showed a tendency to increase initially, then decrease their POV and TBA Number during their heating process. 3. The IV of all oils showed a slight decrease except for oil with frying ingredients added, with showed a substantial decrease. 4. Oil with frying ingredients showed a substantial increase in its oxidized fatty acid level, and others showed a tendency to increase according to the frying time. Decomposition of soybe an oil during the process of frying hot-dogs was studied. Three treatment was performed first, the oil was heated (with hot-dogs) repeatedly four hours in each session, two sessions per day for six days. Second, the oil was heated without hot-dogs under identical condition, Third, the oil was heated constantly for 48 hours.

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Emotional Intelligence Profile and Employee Attitude

  • Seoyeon LEE;Jaeseung MOON
    • East Asian Journal of Business Economics (EAJBE)
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    • v.11 no.2
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    • pp.1-13
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    • 2023
  • Purpose - The purpose of this study is to identify emotional intelligence (EI) profiles according to the sub-factors of the ability EI model, namely, self-emotional appraisal, others' emotional appraisal, regulation of emotion, and use of emotion. In addition, this study aims to reveal whether there is a difference in job satisfaction, affective commitment, and turnover intention depending on the profile. Research design, data, and methodology - For the study, 536 survey responses were analyzed using SPSS 22 and MPlus 8.4. Result - The analysis identified four EI profiles. These were 1) middle-low generalized EI (all sub-factors of EI were slightly lower than the average level), 2) middle-high generalized EI (all sub-factors of EI were slightly higher than the average), 3) low generalized EI (all EI sub-factors were much lower than the average), and 4) high generalized EI (all EI sub-factors were much higher than average). Furthermore, significant differences were found in job satisfaction, affective commitment, and turnover intention according to each profile. Conclusion - This study expands the EI theory by revealing the profile of EI. In addition, this study investigated the impact of EI profile on job satisfaction, affective commitment, and turnover intention.

Morphometric Study on Regeneration of Vascularized Nerve Graft (혈행화 신경이식 후 신경재생에 대한 형태계측학적 연구)

  • Tark, Kwan-Chul;Ahn, Sung-Jun;Kim, Dae-Yong;Lee, Young-Ho
    • Archives of Reconstructive Microsurgery
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    • v.6 no.1
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    • pp.9-28
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    • 1997
  • Adequate vascularization is pivotally essential for a successful nerve graft. Theoretically, the immediate vascularization will inhibit fibroblast infiltration and stimulate nerve cell regeneration. In this study, histomorphological and electrophysiological studies were performed to determine if vascularized grafts are functionally superior. In rat model, a 4cm segment of the sciatic nerve was obtained and placed as a non vascularized graft on one side, and as a vascularized graft connected to the inferior gluteal vessels on the opposite side. To determine the compound action potential of the gastrocnemius muscle, electromyography was done after 2, 3 and 4 months. Histomorphologically, the distribution of myelinated nerve fibers and Schwann cell were evaluated after toluidine blue staining, The following resutls were obtained: 1. The electrophysiological studies showed no difference between the nonvascularized and vascularized grafts. 2. Two and three months after grafting, myelinated nerve fibers were more abundant in the vascularized proximal, middle and distal areas in all nerve fibers of varying diameters. 3. In the post-nonvascularized graft 2-month group, a few myelinated nerve fibers were present in the proximal and middle areas, but none distally. In the post-vascularized graft 2 month group, myelinated nerve fibers ranging $2-8{\mu}m$ were present in all three areas. 4. In the post-nonvascularized graft 3 month group, a few myelinated nerve fibers ranging in $2-6{\mu}m$ were present in all three areas, but in the post-vascularized graft 3 month group, many myelinated nerve fibers ranging in $2-10{\mu}m$ were present in all three areas. 5. In the post-graft 4-month group, more myelinated nerve fibers were present in all three areas of the vascularized grafts. However, nerve fibers of less than $2{\mu}m$ in diameter were more abundant in the non vascularized grafts. 6. Schwann cells were more abundant in the proximal, middle and distal areas of the post-vascularized 2, 3 and 4-month grafts. Based on these findings, the immediate restoration of circulation in vascularized nerve grafts allows for the increased number of surviving Schwann cells, rapid healing of the axon and myelin sheath changes which occur during Wallerian degeneration, and thus is able to stimulate a morphologically optimal regeneration.

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Effects of Zinc Deficiency on Immune Response in Mouse (식이 아연이 Mouse의 면역 반응에 미치는 영향에 관한 연구)

  • 명춘옥
    • Journal of Nutrition and Health
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    • v.21 no.2
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    • pp.113-121
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    • 1988
  • The purpose of this study was to investigate the effects of dietary zinc on immune response in mice. Weanling male mice was placed individually in stainless steel cages and fed a zinc dificient diet and control diet. All mice were given deionized water ad libitum. The introduction of extraneous zinc was minimized in all cage by washing feed jars and water bottles sequentially with 4mM EDTA and conc-nitiric acid followed by deionized water. After 4 and 5 weeks of the diets, mice were immunized with lx 106 Naegleria fowleri intraperitoneally. Mice were weighed once a week. The results from this study are summarized as followed ; 1) Mice fed the zinc dificient diet showed growth retardation. After 3 weeks of diets, mean body weight of zinc deficient mice was 21.4g and that of control was 25.0g. This difference is singnificant statistically (p<0.01). The more time passed, the more remarkable difference was found. 2) The weigth of organs were measured on liver, kidney, spleen, thymus, heart, lung, brain. Difference in weight were observed only in liver and spleen. 3) Proliferative response of spleen cells of zinc deficient mice to con A was lower than that of control mice after one week on immunization(p<0.005). 4) Stimulation index was lower in zinc deficient mice to phytohemagglutinin after two weeks on immunization (p<0.05). 5) Blastogenesis of speen cells of zinc deficient mice to Naegleria fowleric lysate was lower after 10 days on immunization (p<0.05). 6) Immunoglobulin G antribody titers of zinc deficient mice sera by ELISA was lowered to control mice after 5 weeks on immunization (p<0.005).

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Annual Open Heart Surgery: Report of 416 Cases in 1980 (연간 개심술 416례 보고 [1980 년도])

  • 이영균
    • Journal of Chest Surgery
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    • v.14 no.1
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    • pp.17-25
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    • 1981
  • In 1980, 416 cases of open heart surgery were done in this Department with over all operative mortality of 12.3%. 1. There were 288 congenital anomalies consisting of 174 acyanotic and 114 cyanotic varieties, which showed operative mortality of 6.9% and 25.4% respectively. 2. There were 128 cases of acquired lesions, 124 valvular disease and 3 myxoma being the main lesions. 3. There were 128 cases of valve replacement with operative mortality of 7.8%. 4. The most frequently operated anomaly was VSD, 90 pure VSD and 21 cases were associated with one or 2 cardiac anomalies. Over all operative mortality in 111 VSD cases was 8.1% but in 90 pure VSD cases it was 6.7%. 5. Tetralogy of Fallot showed the highest incidence in cyanotic group with 88 cases, consisting of 68 pure and 20 with other cardiac anomalies. Over all mortality in 88 cases was 19.3% but in pure form 16.2%. 6. In 128 valve replacement cases over all mortality was 9.4%. There were 85 mitral, 11 aortic, 2 tricuspid, 21 mitral with aortic, 6 mitral with tricuspid, 3 mitral, aortic, and tricuspid valve replacement cases. For mitral valve replacement operative mortality was 5.9%. 7. Twenty-one cases of babies under 10kg body weight were operated on with over all operative mortality of 28.6%. Sixteen cases of VSD were found with operative mortality of 25%. 8. Among 128 cases of valve replacement 7 were under the age of 15 years and 12 were between 15 and 20 years old. Five pediatric cases underwent mitral valve replacement without mortality, 9 year old boy was the youngest among them. In this Department open heart surgery for infancy and complex anomalies showed still hip operative risk which should be improved in the coming years. For open heart surgery Shiley oxygenators and 2 sets of A-O de-lux 5 head roller pump were utilized exclusively. For valve replacement Ionescu-Shiley bovine pericardial xenografts were mainly used. In pediatric and rural patients Persantin with aspirin regimen was satisfactorily administered for anticoagulation after valve replacement. Routinely Coumadin was administered for one year after valve replacement* In patients who had thrombus on valve sites, chronic atrial fibrillation, and giant left atrium Persantin-Aspirin regimen was used when one year coumadin administration was discontinued.

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