• Journal of Ginseng Research
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• 제16권3호
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• pp.175-182
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• 1992

Intravenous administration of saponin from the root of Panax ginseng (red ginseng) lowered the blood pressure in a dose-dependent manner (10~100 mg/kg B.W) in anesthetized rats. Therefore, experiments were designed to study whether this lowering of blood pressure is associated with the release of endothelium-derived relaxing factor. Rings of thoracic aorta with and without endothelium were suspended for the measurement of isometric tension in organ chamber. All experiments were performed in the presence of indomethacin (10-5 M). Ginseng saponin (10-5~3$\times$10-4 g/ml) relaxed contractions induced by phenylephrine (10-5 M) in the aorta with endothelium but not in that without endothelium. Treatment of aortic rings with NG_monomethyl-L-arginine (L-NMMA 10-4 M for 30 min), a competive inhibitor of nitric oxide synthase and methylene blue (M.B., 3$\times$10-7 M for 30 min), an inhibitor of soluble guanylate cyclase, diminished the relaxation induced by ginseng saponin. In thoracic aortic rings from rats treated with ginseng saponin for 2 weeks intraperitoneally, the relaxation to acetylcholine was increased compared with non-ginseng treated rings. These data suggest that red ginseng saponin evokes hypotension and that vascular relaxations induced by red ginseng saponin are inediatpd by release of endothelium-derived relaxing factor.

• 한국식품영양과학회지
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• 제28권1호
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• pp.94-99
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• 1999

This study was carried out to determine the inhibitory effect of juice of garlic, onion, ginger and red pepper against Staphylococcus aureus, Salmonella enteritidis, Vibrio parahaemolyticus and Enterobacter cloacae which are food born disease organisms. It was found that 1~2.5%(wt/vol.) garlic juice showed strong antimicrobial action against growth of all test bacteria at 1/20$\times$10-6 dilution. Especially 1% garlic juice completly inactivated Vibrio parahaemolyticus but approximately 71.9~88% of reduction at same concentration in other bacteria was occurred. 2.5% onion juice had 28.5% antimicrobial activity on Sal. enteritidis, but 50% reduction was occurred on St.aureus and V. parahaemolyticus at same concentration. Antibacterial activity of ginger juice was similar to that of onion juice. 2.5% ginger juice showed approximately 50% reduction on Sal. enteritidis and V.parahaemolyticus, but less antimicrobial activity was occured on St. aureus and E. cloacae. Red pepper juice showed the least antimicrobial activity on food born disease organism compared to that of other juices. 2.5% red pepper juice showed 11.3%, 18.7% and 8.1% reduction on St. aureus, Sal. enteritidis and V.parahaemolyticus, respectively.

• 생명과학회지
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• 제17권10호
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• pp.1394-1399
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• 2007

홍삼 추출액 제품의 변패원인균을 분리동정하고 생화학적 특성 및 병원성 유무를 판단하였다. 분리된 5가지의 균주는 각각 Bacillus subtilis, Bacillus sp., Paenibacillus sp., Micrococcus sp., Pseudomonas sp.로 동정되었으며, 이 중 Bacillus subtilis와 Paenibacillus sp., Micrococcus sp.는 홍삼 추출액의 원재료로부터 기인한 내생포자를 형성하는 내열성 균주로 추정되었다. 분리된 군주 대부분은 낮은 염도와 중성 pH 조건에서 잘 자라며, 영양요구성이 단순한 호중온성 세균들이었다. 또한 용혈성과 설사유발성을 나타내지 않았으며, 흰쥐 (rat)를 이용한 피부혈관 투과성 항진작용 실험에서도 음성을 나타내어, 수행한 실험 결과 내에서는 분리된 5균주 모두 병원성이 없는 것으로 판단되었다.

• 한국환경농학회:학술대회논문집
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• 한국환경농학회 2011년도 30주년 정기총회 및 국제심포지엄
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• pp.188-195
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• 2011

Red lateritic soils are typically low in total organic carbon (TOC) and available phosphorus (AP) content and continuous fertilization is required to obtain desired crop yield. In this experiment, cattle manure in three forms (air-dried, composted and vermicomposted) were applied to red lateritic soil to study their effect on TOC and AP content of soil and probable mechanism of P-solubilization as affected by these treatments were also studied. Vermicompost was the most effective to solubilize insoluble P in red lateritic soil (Alfisols) as compared to other organic amendments (air-dried cattle manure and compost). The highest SPA in vermicompost-treated soil attributed to the comparatively higher concentration of all the three SPA isozymes in these soils. The maximum P-solubilization in these soils might be attributed to the highest SPA and presence of several organic acids like citric, lactic and oxalic acids in vermicompost-treated soils. Since, vermicompost application also increased TOC, mineralizable N and exchangeable K content of soil, vermicompost could be considered as the most rational organic amendment to improve chemical properties of red lateritic soils.

• Journal of the Korean Wood Science and Technology
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• 제49권6호
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• pp.602-615
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• 2021

Red jabon wood is a potential fast-growing species for veneer, furniture, and many other wood products, but its durability is very low. The purpose of this study was to investigate the effects of castor bean oil and heating on boron leaching, dimensional stability, and resistance to decay fungi in treated jabon wood. Red jabon wood was preserved with boron solutions containing 5% boron (boric acid, borax, or borax-boric acid). Following that, castor bean oil impregnation and heating were used as posttreatments. Furthermore, all the wood samples were tested in terms of leaching, dimensional stability, and resistance against Schizophyllum commune and Fomitopsis palustris fungi. This study discovered that boron compounds, castor bean oil, and heating treatments influenced the leaching, dimensional stability, and resistance of red jabon wood to decay fungi. The double impregnation of boric acid or borax and castor bean oil, followed by heating at 160℃, significantly reduced water absorption and leaching while increasing the dimensional stability and resistance of red jabon wood against the two tested decay fungi.

• 한국식품저장유통학회지
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• 제30권2호
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• pp.224-234
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• 2023

We analyzed the major quality characteristics of red pepper powders from various regions and predicted these characteristics nondestructively using shortwave infrared hyperspectral imaging (HSI) technology. We conducted partial least squares regression analysis on 70% (n=71) of the acquired hyperspectral data of the red pepper powders to examine the major quality characteristics. R_c² values of ≥0.8 were obtained for the ASTA color value (0.9263) and capsaicinoid content (0.8310). The developed quality prediction model was validated using the remaining 30% (n=35) of the hyperspectral data; the highest accuracy was achieved for the ASTA color value (R_p²=0.8488), and similar validity levels were achieved for the capsaicinoid and moisture contents. To increase the accuracy of the quality prediction model, we conducted spectrum preprocessing using SNV, MSC, SG-1, and SG-2, and the model's accuracy was verified. The results indicated that the accuracy of the model was most significantly improved by the MSC method, and the prediction accuracy for the ASTA color value was the highest for all the spectrum preprocessing methods. Our findings suggest that the quality characteristics of red pepper powders, even powders that do not conform to specific variables such as particle size and moisture content, can be predicted via HSI.

• Journal of Ginseng Research
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• 제37권3호
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• pp.371-378
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• 2013

Serum and liver metabolites in rats fed red ginseng (RG) were analyzed by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry. The mass data were analyzed by partial least squares-discriminant analysis (PLS-DA) to discriminate between control and RG groups and identify metabolites contributing to this discrimination. The RG group was clearly separated from the control group on PLS-DA scores plot for serum samples, but not liver samples. The major metabolites contributing to the discrimination included lipid metabolites (lysophosphatidylcholine, acyl-carnitine, and sphingosine), isoleucine, nicotinamide, and corticosterone in the serum; the blood levels of all but isoleucine were reduced by RG administration. Not all metabolites were positively correlated with the health benefits of RG. However, the blood levels of lysophosphatidylcholine, which stimulate various diseases, and long-chain acylcarnitines and corticosterone, which activate the stress response, were reduced by RG, suggesting long-term RG might relieve stress and prevent physiological and biological problems.

• 대한수의학회지
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• 제48권2호
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• pp.175-179
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• 2008

Parallux, a solid-phase fluorescence immunoassay (SPFIA) developed for detection antibiotics residue in milk, was applied for analysis of antibiotics in muscle tissue of olive flounder (Paralichthys olivaceus), rockfish (Sebastes schlegeli), and red sea bream (Pagrus major). Fishes were dipped in neomycin 140 mg/ton water, the recommended therapeutic dose, for 24 h. Muscle samples were obtained on 1st, 2nd, 3rd, 4th and 5th day after drug treatment. The concentration of neomycin in muscle was determined using an internal standard (100 ppb as neomycin). The absorbance ratio of sample to internal standard (S/C) was employed as an index to determine the muscle residues in fishes. To investigate the recovery rate, the standard solutions were added to muscle samples to give final concentrations in muscle of 0.2 and 0.5 mg/ml. The recovery rates of all spiked samples were > 85% of the spiked value. Neomycin was detected in muscles of fishes treated after the 1st day of withdrawal period. On the 2nd day after drug treatment, all muscle samples showed negative reaction (S/C ration ${\leq}$ 1.0). The present study showed that the SPFIA can be applied for predicting residues of neomycin in muscle tissues of farmed fishes.

• Journal of Ginseng Research
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• 제19권1호
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• pp.39-44
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• 1995

Total saponin from Korean red ginseng changed thermodynamic parameters of membranes from dipalmitoylphosphatidylcholine (DPPC) and ghost erythrocytes of human. In liposomes from DPPC, temperature of the main transition (Lb'-La) in liquid-crystalline phase increases by 0.2$^{\circ}C$ in average, but enthalpy does not change. Total saponin at a concentration of smaller than $10^5$% "stabilizes" the timid bilayers. At larger than 0.07 of saponin/DPPC ratio, saponin leads to an exclusion of the bound lipid molecules from the main phase transition into lamella liquid crystalline La-phase. Total saponin influences specifically all erythrocyte membrane transitions in a concentration-dependent manner, i.e. on the structures of all the main membrane skeleton proteins. A high structural specificity of saponin with membrane proteins, could be a base of specificity of physiological response of not only erythrocytes, but also other cells.her cells.

• Journal of Ginseng Research
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• 제19권1호
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• pp.17-21
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• 1995

A study was designed to investigate the effectiveness of Korean Red Ginseng (ERG) as an oral agent for erectile dysfunction (EF), which was compared to that of placebo and trazodone. Patients who were believed to have EF of mild or non-organic etiologies, randomized into 3 groups to receive 600 mg KRG 3 times daily (group A), placebo (group B) and 25mg trazodone once a day after evening (group C). All agents were given orally. Ninety patients, composed of 30 in each group, were included and analyzed only when clinical follow-up could be achieved at the end of the study for at least 3 months. There were no significant differences(p>0.05) between each group in mean age (43.7 years), duration of EF (5.8 years), the state of marriage (married : 80 patients) and duration of marriage (18.2 years). In group A, the parameters such as rigidity and tumescence on erection, early detumescence, libido and patient's satisfaction were significantly more effective than that of other group (p<0.05). But there were no significant differences in the parameters such as the frequency of coitus, premature ejaculation and morning erection between 3 groups (p>0.05). The efficacy achieved with KGR (60%) was significantly higher (p<0.05) than that of placebo (30%) and trazodone (30%). There were no significant changes on level of serum testosterone and type of AVS-penogram in group A. No side effect was demonstrated in all patients.