• 제목/요약/키워드: All India Institute of Medical Sciences

검색결과 175건 처리시간 0.032초

Pulmonary Strongyloidiasis Masquerading as Exacerbation of Chronic Obstructive Pulmonary Disease

  • Pradhan, Gourahari;Behera, Priyadarshini;Panigrahi, Manoj Kumar;Bhuniya, Sourin;Mohapatra, Prasanta Raghab;Turuk, Jyotirmayee;Mohanty, Srujana
    • Tuberculosis and Respiratory Diseases
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    • 제79권4호
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    • pp.307-311
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    • 2016
  • Pulmonary strongyloidiasis is an uncommon presentation of Strongyloides infection, usually seen in immunocompromised hosts. The manifestations are similar to that of acute exacerbation of chronic obstructive pulmonary disease (COPD). Therefore, the diagnosis of pulmonary strongyloidiasis could be challenging in a COPD patient, unless a high index of suspicion is maintained. Here, we present a case of Strongyloides hyperinfection in a COPD patient mimicking acute exacerbation, who was on chronic steroid therapy.

Atlanto-occipital assimilation: embryological basis and its clinical significance

  • Hari Hara Hanusun N;Akanksha Singh;Pooja Poddar;Jessy J P;Neerja Rani;Hitesh Gurjar;Seema Singh
    • Anatomy and Cell Biology
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    • 제57권1호
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    • pp.147-151
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    • 2024
  • Atlanto-occipital assimilation is an osseous embryological anomaly of the craniovertebral junction in which the atlas (C1) is fused to the occiput of skull. Embryologically, this assimilation may happen due to failure of the segmentation and separation of the caudal occipital and the cranial cervical sclerotome. The segmentation clock is maintained by NOTCH and WNT signalling pathways along with Hox genes and retinoic acid. This condition is likely to be a consequence of mutation in above mentioned genes. The knowledge of this assimilation may be crucial for the clinicians as it may lead to various neurovascular symptoms. The present case report involves the analysis of atlanto-occipital assimilation with its clinical significance and embryological basis.

Isolated primary hydatid cyst of the pancreas: Management challenges of a cystic masquerade

  • Pradeep Kumar Kothiya;Vishal Gupta;Radha Sarawagi;Erukkambattu Jayashankar;Jitendra Sharma;Hamza Wani;Karunagaran Balaji;J. Roshny
    • 한국간담췌외과학회지
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    • 제26권4호
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    • pp.401-406
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    • 2022
  • Abdominal hydatid cyst disease mostly involves the liver. Involvement of the pancreas as an isolated primary organ is rare accounting for < 2% of all systemic echinococcosis cases. It mostly involves the head of the pancreas. Symptoms depend on the location, size, and associated complications; therefore, it can have varied presentations including acute pancreatitis. On imaging, it can mimic other common pancreatic cystic lesions like pseudocyst or cystic neoplasm. Accurate preoperative diagnosis is usually difficult and requires a very high index of suspicion even in endemic areas. Herein, a case of primary isolated hydatid cyst of the pancreas that was initially diagnosed and managed as acute pancreatic pseudocyst is reported.

Malignant Schwannoma of the Esophagus: A Rare Case Report

  • Mishra, Biswajit;Madhusudhan, Kumble Seetharama;Kilambi, Ragini;Das, Prasenjit;Pal, Sujoy;Srivastava, Deep Narayan
    • Journal of Chest Surgery
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    • 제49권1호
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    • pp.63-66
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    • 2016
  • Neurogenic tumors are the most prevalent tumors of the mediastinum, and schwannomas are the most common type of neurogenic tumor. Primary neurogenic neoplasm of the esophagus is uncommon and malignant schwannoma of the esophagus is extremely rare. We report a case of a 27-year-old female presenting with dysphagia and palpitations who was found to have a lobulated tumor in the mediastinum that was compressing the esophageal lumen. The tumor was successfully treated surgically without recurrence. The final diagnosis, on histopathological examination of the specimen, was malignant schwannoma.

Extrapulmonary Small Cell Carcinoma - a Case Series of Oropharyngeal and Esophageal Primary Sites Treated with Chemo-Radiotherapy

  • Sahai, Puja;Baghmar, Saphalta;Nath, Devajit;Arora, Saurabh;Bhasker, Suman;Gogia, Ajay;Sikka, Kapil;Kumar, Rakesh;Chander, Subhash
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권16호
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    • pp.7025-7029
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    • 2015
  • Background: The optimal sequence and extent of multimodality therapy remains to be defined for extrapulmonary small cell carcinoma because of its rarity. The purpose of our study was to assess the response to neoadjuvant chemotherapy followed by chemoradiation/radiation in patients with extrapulmonary small cell carcinoma. Materials and Methods: Four consecutively diagnosed patients were included in this study. The primary tumor site was oropharynx in three patients and esophagus in one. The patients with the limited disease were treated with chemotherapy followed by concurrent chemoradiation (n=2) or radiotherapy (n=1). The patient with the extensive disease with the primary site in vallecula was treated with chemotherapy and palliative radiotherapy to the metastatic site. Results: The median follow-up was 22.5 months (range, 8-24 months). Three patients with the limited disease (base of tongue, n=2; esophagus, n=1) were in complete remission. The patient with the extensive disease died of loco-regional tumor progression at 8 months from the time of diagnosis. Conclusions: The combination of chemotherapy and radiotherapy is the preferred therapeutic approach for patients with extrapulmonary small cell carcinoma. Induction chemotherapy followed by concurrent chemoradiation or radiation provides a good loco-regional control in patients with limited disease.

Type-Specific Incidence and Persistence of HPV Infection among Young Women: A Prospective Study in North India

  • Datta, Palika;Bhatla, Neerja;Pandey, R.M.;Dar, Lalit;Patro, A. Rajkumar;Vasisht, Shachi;Kriplani, Alka;Singh, Neeta
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권3호
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    • pp.1019-1024
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    • 2012
  • Background: Infections with human papillomavirus (HPV) are highly prevalent among sexually active young women in India. However, not much is known about the incidence of type-specific human papillomavirus (HPV) infections and their patterns of persistence, especially in the Indian context. Objective: The objective of this study was to evaluate the rate of acquisition and persistence of HPV types in young women. Methods: Women residing in an urban slum in Delhi (n=1300) were followed for 24 months at 6 monthly intervals. Exfoliated cervical cells collected at each visit were tested for the presence of HPV DNA. Genotyping was performed using the reverse line blot assay. Results: The incidence rate for any HPV type was calculated to be 5 per 1000 women-months. Among high risk HPV types, HPV16 had the highest incidence rate followed by HPV59, HPV52 and HPV18, i.e., 3.0, 0.58, 0.41 and 0.35 women per 1000 women-months respectively. The persistence rate was higher for high-risk than low-risk HPV types. Among low-risk types, HPV42, HPV62, HPV84 and HPV89 were found to persist. Whereas almost all high risk types showed persistence, the highest rate was found in women with HPV types 16, 45, 67, 31, 51 and 59. The persistence rate for HPV16 infection was 45 per 1000 women-months. Conclusion: Incident HPV infections and high risk HPV type-specific persistence were found to be high in our study population of young married women. Understanding the patterns of HPV infection may help plan appropriate strategies for prevention programs including vaccination and screening.