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Device modelling and performance analysis of two-dimensional AlSi3 ballistic nanotransistor

  • Chuan, M.W.;Wong, K.L.;Hamzah, A.;Rusli, S.;Alias, N.E.;Lim, C.S.;Tan, M.L.P.
    • Advances in nano research
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    • v.10 no.1
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    • pp.91-99
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    • 2021
  • Silicene is an emerging two-dimensional (2D) semiconductor material which has been envisaged to be compatible with conventional silicon technology. This paper presents a theoretical study of uniformly doped silicene with aluminium (AlSi3) Field-Effect Transistor (FET) along with the benchmark of device performance metrics with other 2D materials. The simulations are carried out by employing nearest neighbour tight-binding approach and top-of-the-barrier ballistic nanotransistor model. Further investigations on the effects of the operating temperature and oxide thickness to the device performance metrics of AlSi3 FET are also discussed. The simulation results demonstrate that the proposed AlSi3 FET can achieve on-to-off current ratio up to the order of seven and subthreshold swing of 67.6 mV/dec within the ballistic performance limit at room temperature. The simulation results of AlSi3 FET are benchmarked with FETs based on other competitive 2D materials such as silicene, graphene, phosphorene and molybdenum disulphide.

Assessing the Root Development and Biomass Allocation of Magnolia champaca under Various Mulching at Montane Rainforest Cameron Highlands, Pahang, Malaysia

  • Wahidullah Rahmani;Frahnaz Azizi;Mohamad, Azani Bin Alias
    • Journal of Forest and Environmental Science
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    • v.39 no.2
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    • pp.96-104
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    • 2023
  • The successful restoration program requires a comprehensive understanding of variables influencing seedling efficiency. Below-ground is hypothesized to have a major impact on seedling performance of species when planted in agriculture, and degraded areas with different types of mulching. This study investigated on Sg. Terla Forest Reserve in Cameron Highlands Pahang, Malaysia. In this study randomized complete block design (RCBD) was used. The excavation method was applied to study the root system development, above, and below ground biomass distributions under different types of mulching: coconut mulching (CM), oil palm mulching (OM), plastic mulching (PM) and control (CK). The root diameter, main root length, lateral root length, root coiling, and root direction toward to sun were recorded. The results in this study indicate that mulching had significant effect on root diameter, main root length, and root distributions among treatments while for lateral root length, root: shoot ratio, dry biomass distributions, and above and below ground biomass did not showed significant effect among treatments. The highest values for root diameter, lateral root length, main root length, root distributions, dry biomass distributions and above and below ground biomass were showed in CM treatments. However 75% of root coiling was observed in seedlings between treatments.

Developing an Integrated Acupuncture Protocol for Treating Medial Tibial Stress Syndrome: A Delphi Consensus Study

  • Pradeep M.K. Nair;Gita Sharma;Deepika Singh;Mamta Jagwani;Anu Alias;Hassan Kodandarama Gurudatta;Radhakrishnan Shubha;Sreedhar Pulipatti;Nagaraja Nagajyothi;Anjali Sharma;Janak Bahadur Basnet;Kalpana Devi;Karuppaiah Muthukrishnan;Kajal Gupta
    • Journal of Acupuncture Research
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    • v.41
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    • pp.160-167
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    • 2024
  • The present study employs the Delphi method to devise a consensus-based protocol for utilizing integrated acupuncture in treating medial tibial stress syndrome (MTSS). Twenty acupuncture experts contributed opinions across six key themes, including diagnosis, acupuncture points, additional Traditional Oriental Medicine modalities, treatment rationale, treatment duration/frequency, and integration of yoga/naturopathic therapies. Consensus, defined as a 70% agreement or higher, was reached on all themes, reflecting a collective acknowledgment of the necessity for a holistic approach to MTSS management. The final protocol includes six diagnostic criteria, six acupuncture points, one additional modality, two Traditional Oriental Medicine therapies, four treatment rationales, and six yoga/naturopathic therapies. The present comprehensive protocol offers valuable guidance for healthcare professionals seeking an integrated approach to MTSS management.

Ectopic Overexpression of COTE1 Promotes Cellular Invasion of Hepatocellular Carcinoma

  • Zhang, Hai;Huang, Chang-Jun;Tian, Yuan;Wang, Yu-Ping;Han, Ze-Guang;Li, Xiang-Cheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.11
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    • pp.5799-5804
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    • 2012
  • Family with sequence similarity 189, member B (FAM189B), alias COTE1, a putative oncogene selected by microarray, for the first time was here found to be significantly up-regulated in hepatocellular carcinoma (HCC) specimens and HCC cell lines. mRNA expression of COTE1 in HCC samples and cell lines was detected by reverse transcription-polymerase chain reaction (RT-PCR) and real-time PCR, while protein expression of COTE1 in HCC tissues was assessed by immunohistochemistry. In addition, invasion of HCC cells was observed after overexpressing or silencing COTE1. In the total of 48 paired HCC specimens, compared with the adjacent non-cancer tissues, the expression of COTE1 was up-regulated in 31 (p<0.01). In HCC cell lines, COTE1 expression was significantly higher than in normal human adult liver (p<0.01). Overexpression of COTE1 enhanced HCC-derived LM6 and MHCC-L cellular invasion in vitro. In contrast, COTE1 knockdown via RNAi markedly suppressed these phenotypes, as documented in LM3 and MHCC-H HCC cells. Mechanistic analyses indicated that COTE1 could physically associate with WW domain oxidoreductase (WWOX), a tumor suppressor. COTE1 may be closely correlated with invasion of hepatocellular carcinoma (HCC) cells and thus may serve as an effective target for gene therapy.

Gelam Honey and Ginger Potentiate the Anti Cancer Effect of 5-FU against HCT 116 Colorectal Cancer Cells

  • Hakim, Luqman;Alias, Ekram;Makpol, Suzana;Ngah, Wan Zurinah Wan;Morad, Nor Azian;Yusof, Yasmin Anum Mohd
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.11
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    • pp.4651-4657
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    • 2014
  • The development of chemopreventive approaches using a concoction of phytochemicals is potentially viable for combating many types of cancer including colon carcinogenesis. This study evaluated the anti-proliferative effects of ginger and Gelam honey and its efficacy in enhancing the anti-cancer effects of 5-FU (5-fluorouracil) against a colorectal cancer cell line, HCT 116. Cell viability was measured via MTS (3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulphenyl)-2H-tetrazolium) assay showing ginger inhibiting the growth of HCT 116 cells more potently ($IC_{50}$ of 3mg/mL) in comparison to Gelam honey ($IC_{50}$ of 75mg/mL). Combined treatment of the two compounds (3mg/mL ginger+75mg/mL Gelam honey) synergistically lowered the $IC_{50}$ of Gelam honey to 22mg/mL. Combination with 35 mg/mL Gelam honey markedly enhanced 5-FU inhibiting effects on the growth of HCT 116 cells. Subsequent analysis on the induction of cellular apoptosis suggested that individual treatment of ginger and Gelam honey produced higher apoptosis than 5-FU alone. In addition, treatment with the combination of two natural compounds increased the apoptotic rate of HCT 116 cells dose-dependently while treatment of either ginger or Gelam honey combined with 5-FU only showed modest changes. Combination index analysis showed the combination effect of both natural compounds to be synergistic in their inhibitory action against HCT 116 colon cancer cells (CI 0.96 < 1). In conclusion, combined treatment of Gelam honey and ginger extract could potentially enhance the chemotherapeutic effect of 5-FU against colorectal cancer.

Relationships between dielectric properties and characteristics of impregnated and activated samples of potassium carbonate-and sodium hydroxide-modified palm kernel shell for microwave- assisted activation

  • Alias, Norulaina;Zaini, Muhammad Abbas Ahmad;Kamaruddin, Mohd Johari
    • Carbon letters
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    • v.24
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    • pp.62-72
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    • 2017
  • The aim of this work was to evaluate the dielectric properties of impregnated and activated palm kernel shells (PKSs) samples using two activating agents, potassium carbonate ($K_2CO_3$) and sodium hydroxide (NaOH), at three impregnation ratios. The materials were characterized by moisture content, carbon content, ash content, thermal profile and functional groups. The dielectric properties were examined using an open-ended coaxial probe method at various microwave frequencies (1-6 GHz) and temperatures (25, 35, and $45^{\circ}C$). The results show that the dielectric properties varied with frequency, temperature, moisture content, carbon content and mass ratio of the ionic solids. PKSK1.75 (PKS impregnated with $K_2CO_3$ at a mass ratio of 1.75) and PKSN1.5 (PKS impregnated with NaOH at a mass ratio of 1.5) exhibited a high loss tangent ($tan{\delta}$) indicating the effectiveness of these materials to be heated by microwaves. $K_2CO_3$ and NaOH can act as a microwave absorber to enhance the efficiency of microwave heating for low loss PKSs. Materials with a high moisture content exhibit a high loss tangent but low penetration depth. The interplay of multiple operating frequencies is suggested to promote better microwave heating by considering the changes in the materials characteristics.

Sea Level Variabilities in the East Asian Marginal Seas by Topex/Poseidon Altimeter Data (Topex/Poseidon 고도계자료를 이용한 동북아시아 연변해역의 해수면 변화 연구)

  • Yoon, Hong-Joo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.5 no.6
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    • pp.1190-1194
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    • 2001
  • The first 7 years of altimeter data from the TOPEX/POSEIDON(T/P) were analyzed to study the surface circulation and its variability in the East Asian Marginal Seas. Long term averaged T/P sea level time series data where compared with in situ sea level measurements from a float-operated type tide gauge around of south Korea and Japan. T/]P data are a large contaminated by 60-day tidal aliasing effect, very near the alias periods of M2 and 52. When this 60-day effect is removed, the data agree well with the tide gauge data with 4.6 cm averaged RMS difference. The T/P derived sea level variability reveals clearly the well-known, strong current-topography such as Kuroshio. The T/P mean sea level of North Pacific(NP) was higher than Yellow Sea(YS) and East Sea(ES). The T/P sea level variability, with strong eddy and meandering, was the largest in eastern part of Japan and this variability was mainly due to the influence of bottom topography in Kuroshio Extension area.

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A Modular Pointer Analysis using Function Summaries (함수 요약을 이용한 모듈단위 포인터분석)

  • Park, Sang-Woon;Kang, Hyun-Goo;Han, Tai-Sook
    • Journal of KIISE:Software and Applications
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    • v.35 no.10
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    • pp.636-652
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    • 2008
  • In this paper, we present a modular pointer analysis algorithm based on the update history. We use the term 'module' to mean a set of mutually recursive procedures and the term 'modular analysis' to mean a program analysis that does not need the source codes of the other modules to analyze a module. Since a modular pointer analysis does not utilize any information on the callers, it is difficult to design a precise analysis that does not lose the information related to the program flow or the calling context. In this paper, we propose a modular and flow- and context-sensitive pointer analysis algorithm based on the update history that can memory states of a procedure independently of the information on the calling context and keep the information on the order of side effects performed. Such a memory representation not only enables the analysis to be formalized as a modular analysis, but also helps the analysis to effectively identify killed side effects and relevant alias contexts.

Performance Modelling of Adaptive VANET with Enhanced Priority Scheme

  • Lim, Joanne Mun-Yee;Chang, YoongChoon;Alias, MohamadYusoff;Loo, Jonathan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.4
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    • pp.1337-1358
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    • 2015
  • In this paper, we present an analytical and simulated study on the performance of adaptive vehicular ad hoc networks (VANET) priority based on Transmission Distance Reliability Range (TDRR) and data type. VANET topology changes rapidly due to its inherent nature of high mobility nodes and unpredictable environments. Therefore, nodes in VANET must be able to adapt to the ever changing environment and optimize parameters to enhance performance. However, there is a lack of adaptability in the current VANET scheme. Existing VANET IEEE802.11p's Enhanced Distributed Channel Access; EDCA assigns priority solely based on data type. In this paper, we propose a new priority scheme which utilizes Markov model to perform TDRR prediction and assign priorities based on the proposed Markov TDRR Prediction with Enhanced Priority VANET Scheme (MarPVS). Subsequently, we performed an analytical study on MarPVS performance modeling. In particular, considering five different priority levels defined in MarPVS, we derived the probability of successful transmission, the number of low priority messages in back off process and concurrent low priority transmission. Finally, the results are used to derive the average transmission delay for data types defined in MarPVS. Numerical results are provided along with simulation results which confirm the accuracy of the proposed analysis. Simulation results demonstrate that the proposed MarPVS results in lower transmission latency and higher packet success rate in comparison with the default IEEE802.11p scheme and greedy scheduler scheme.

Data Reductions of Gravity Recovery and Climate Experiment (GRACE) Gravity Solutions and Their Applications (Gravity Recovery and Climate Experiment (GRACE) 중력자료 해석을 위한 자료 처리 및 응용)

  • Seo, Ki-Weon
    • Journal of the Korean earth science society
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    • v.32 no.6
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    • pp.586-594
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    • 2011
  • Gravity Recovery and Climate Experiment (GRACE), launched in April, 2002, makes it possible to monitor Earth's mass redistribution with its time-varying gravity observation. GRACE provides monthly gravity solutions as coefficients of spherical harmonics, and thus ones need to convert the gravity spectrum to gravity grids (or mass grids) via the spherical harmonics. GRACE gravity solutions, however, include spatial alias error as well as noise, which requires to suppress in order to enhance signal to noise ratio. In this study, we present the GRACE data processing procedures and introduce some applications of time-varying gravity, which are studies of terrestrial water storage changes, Antarctic and Greenland ice melting, and sea level rise. Satellite missions such as GRACE will continue up to early 2020, and they are expected to be an essential resource to understand the global climate changes.