• The Journal of the Korean life insurance medical association
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• v.23
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• pp.84-104
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• 2004

• Korean Journal of Biological Psychiatry
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• v.4 no.1
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• pp.43-47
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• 1997

The author attempted to examine the allelic association between the A1 allele of Dopamine $D_2$ receptor and alcoholism in Koreans. The allelic distribution of Taq I polymorphism of the $D_2$ dopamine receptor gene with alcoholism was examined in 67 Korean alcoholics and compared with 100 Korean controls. In alcoholics, the numbers of alcoholics with A1A1, A1A2 and A2A2 were 11(16.4%), 30(44.8%) and 26(38.8%) respectively and in controls with A1A1, A1A2 and A2A2 were 17(17.0%), 42(42.0%) and 41(41.0%), respectively. The prevalence of the A1 allele in alcoholics was 61.2% and 59.0% in controls. And the frequency of the A1 allele in alcoholics and controls were 0.39 and 0.38, respectively. There was not significant difference in the frequency of the A1 allele between alcoholics and controls. This data suggest that the A1 allele is not associated with alcoholism in Koreans. The author conclude that our data do not support an allelic association between the A1 allele at Dopamine $D_2$ receptor and alcoholism. Further systemized studies will be necessary to determine whether the role of allele of Dopamine $D_2$receptor is major effect gene or modifying effect gene in the pathogenesis of alcoholism.

• Korean Journal of Social Welfare
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• v.56 no.4
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• pp.317-343
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• 2004

The purpose of this study is to explore further understanding of variables, besides father's alcoholism, which relates to psychosocial adjustment among ADAF(adult daughters of alcoholic fathers). This study examines the relationship between father's alcoholism, family functioning, parental attachment and the psychosocial adjustment among the ADAF. From a larger sample of 463 female college students, 160 ADAF and a matched group of non-ADAF were identified to participate in the study. This survey was conducted in Seoul and Gyungi-do area. Participants completed self-report questionnaires, "The Korean Version of Children of Alcoholics Screening Test", "Inventory of Parent and Peer Attachment", "Satisfaction With Life Scale", "Self-esteem", "Beck Depression Inventory" and "Family Environment Scale". Path analyses was used to test the research question. Findings indicated that father's alcoholism had no direct effect on both the psychosocial adjustment of the ADAF and the family functioning. But father's alcoholism was significantly related to parental attachment. Family functioning was significant predictor of attachment to parents as well as psychosocial adjustment. Finally family functioning is important cause for parental attachment and psychosocial adjustment, specifically self-esteem and life satisfaction outcomes only. Therefore parental attachment was function as a mediator in the relationship between family functioning and psychosocial adjustment. In conclusion, this study showed that father's alcoholism did not predict outcome. We need to reconsider the assumption that direct link exists between adult adjustment difficulties and the presence of father's alcoholism. Implications for clinical and theoretical work with ADAF are discussed.

• Investigative Magnetic Resonance Imaging
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• v.4 no.2
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• pp.94-99
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• 2000

Purpose : With the use of localized, water-suppressed in vivo $^1H$ magnetic resonance spectroscopy (MRS), we evaluated the proton metabolic alterations in patients with chronic alcoholism and healthy normal controls. Material and Methods : Patients with chronic alcoholism (N = 10) and normal control subjects (N = 10) underwent MRS examinations using a stimulated echo acquisition mode (STEAM) pulse sequence with $2{\times}2{\times}2{\;}\textrm{cm}^3$ volume of interest (VOI) in the left cerebellum and basal ganglia. Proton metabolite ratios relative to creative (Cr) were obtained using a Marquart algorithm. Results : The specific feature in patients with chronic alcoholism was a significant decrease of N-acetylaspartate (NAA)/Cr ratio in the left cerebellum, compared with normal controls. No clear correlation of other metabolite ratios such as choline (Cho)/Cr and inositols (Ins)/Cr was established. Conclusion : Our preliminary study suggests that the reduction of NAA/Cr ratio may indicate neuronal loss in patients with chronic alcoholism. Thus, in vivo 1H MRS may be a useful modality in the clinical evaluation of patients with chronic alcoholism based on the proton metabolite ratios.

• Journal of Physiology & Pathology in Korean Medicine
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• v.19 no.5
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• pp.1292-1295
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• 2005

Effects of the Seokchangpo-Wonji-Tang on recovery from disorder of stomach, liver and mental-faculty in alcoholism were studied using male Sprague-Dawley rats. The rats were assigned into 4 groups; normal, control and Seokchangpo-Wonji-Tang(SWT) group. Control group administered ethanol(25 v/v %) at a dose 3g/kg, while SWT group administered 50mg/kg of SWT 30min before treating same dose of ethanol as control group for 10 days, orally. The gastric ulceration and also GOT and GPT activities in rats were checked, and all groups were subjected to trials of straight channel on the 1st day and to those of multiple T-maze during the following 3 days. The gastric ulceration, GOT and GPT activities were increased in control group, but decreased in SWT group significantly. The time required in normal group for the straight channel of the 2nd and 3rd trials was significantly shorter than that of the 1 st, while the control group showed no significance. In the time required for the multiple T-maze trials, the control group showed no significance. But in the straight or T-maze trials, the SWT group showed significant decrease in the time required against the control group.

• Korean Journal of Psychosomatic Medicine
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• v.7 no.1
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• pp.42-50
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• 1999

Alexithymia refers to a specific disturbance in psychic functioning characterized by difficulties in the capacity to verbalize affect and to elabolate fantasies. Although it was initially described in the context of psychosomatic illness, alexithymic charateristics may be observed in patients with a wide range of medical and psychiatric disorders. This study was designed to investigate alexithymic characteristics in the patients with alcoholism using Scored Archetypal 9 Test(SAT9) and Toronto Alexithymia Scale-20 Korea version(TAS-20K). Twenty patients with alcoholism and twenty-four normal controls completed these tests. The results were as follows. 1) Patient group with alcoholism were significantly more alexithymic than normal control group in both SAT9 and TAS-20K. 2) No significant difference in the alexithymic measures was found between genders of both group. 3) No significant correlation was found between alexithymic measures and age or education level in both group. 4) Measures between SAT9 and TAS-20K showed significant correlation in the patient group.

• Journal of the Korea Society of Computer and Information
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• v.20 no.2
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• pp.157-167
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• 2015

There is literature addressing to cultural aspects of alcohol and alcoholism. However, scholars have paid little attention to study what will happen to alcohol consumption behavior and alcoholism if there is a national government cultural intervention, so that the alcohol drinking culture would change in association with the change of internal institution in a society. This work attempted to study this research question. For this purpose, I selected Mongolia as a research case and examined survey data, statistical data, and data from research-based resources, referring to the last 70 years profile of Mongolian alcohol per capital consumption and alcoholism as well as studying Mongolian historical sources for measuring Mongolian traditional alcohol drinking customs. The data I gathered and observed during this research proved that there is a huge difference between the current drinking culture among younger generation and Mongolian traditional cultural context that was respected and strictly followed by their ancestors. Findings suggest that there has been a parallel increase between the change of alcohol drinking culture and alcohol consumption in connection with the modernization.

• The Journal of Internal Korean Medicine
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• v.22 no.2
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• pp.239-243
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• 2001

Alcoholism is a chronic behavior disorder that disturbs the health, social, and economical functions by intaking alcohol repeatedly. Alcoholism includes some habituation, dependency, and addiction. It may be clinically silent or severe enough to lead to the rapid development of hepatic, renal and gastrointestinal failure. Alcoholism can also cause death. In this case, we administrated saenggangunbitang and sungjoocheonggantang to a patient suffering from alcohoism and its withdrawal symptoms. After administration of saenggangunbitang-sungjoocheonggantang medication, clinical symptoms, including liver function with diabetes mellitus and splenomegaly improved. saenggangunbitang-sungjoocheonggantang showed desirable effect on alcoholism symptoms.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.5 no.4
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• pp.63-70
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• 2015

There is an increasing trend to alcoholics patients due to social factors of the aftereffect of the recession in Korea. Accordingly, study of the impact on society as well as alcoholism impact on individuals is becoming active. To solve the problem of addiction, we needed an integrated management system because the evils of alcoholism and addiction caused by a variety of social, economic and cultural factors. However, alcoholism research investment is less than the health problems like drugs, gambling, internet and we also did not provide proper treatment services for alcohol addiction. In this study, we will develop a customized smart phone application then the patient can acts for the individual circumstances by providing the aggregated information relates to treatment.

• Proceedings of the KIEE Conference
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• 2004.07d
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• pp.2690-2692
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• 2004

Medications or cognitive-behavior methods have been mainly used as a treatment of alcoholism. lately the virtualy technology has been applied to the kink of alcoholic disorders. A virtual environment makes him having ability to over come the drink. In this study, we were implemented by making panorama images and 3D object modules using 3D Studio MAX. VRML, JAVA Applet. And the BAR stimulator that composed with a position sensor head mount display, and audio system, is suggested. To illustrate the physiological difference between a person who has a alcoholism and and without a liquor bottle, heart rate was measured during experiment, and also measured a Person's HR after the virtual reality training. we demonstrated the subjective effectiveness of virtual reality psychotherapy through the clinical experiment.