• Korean Journal of Occupational Health Nursing
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• v.20 no.2
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• pp.119-129
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• 2011

Purpose: This study firstly examined the pattern and prevalence of drinking. Secondly, we investigated the association between various psychosocial work environment and problem drinking among Korean male workers in different age groups. Methods: The study sample was a weighted population of 3,289 (3,289 survey samples) men aged 20 to 64 years who responded to the 2006 Korean Working Condition Survey. Social support from colleague and supervisor, work autonomy, psychological wellbeing at work, and intellectual and emotional work demand were assessed. Results: After considering sociodemographic factors, smoking, occupational characteristics and other psychosocial work environment factors, problem drinking was associated with "intellectual work demand" for the 20~34 year old group. Social support from colleague and supervisor was significantly associated with problem drinking in the 35~49 year old group. For the 50~64 year old group, problem drinking was associated with 'work autonomy'. Conclusion: The present study clarified that certain psychosocial work environmental factors relate to problem drinking, and the association varies among different age groups.

• Pediatric Infection and Vaccine
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• v.6 no.1
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• pp.116-122
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• 1999

Purpose : Despite of development of neonatal intensive care, infections, especially catheter-related infection, have been a major problem in newborns on intensive care. Catheter-related infection is closely related to skin colonization so that skin disinfection is crucial to protect newborns from the infection. Cotton balls of seventy percent alcohol made by hospital frequently open to air so that composition of alcohol may be easily evaporated. We hypothesized that 10% povidone would have better disinfection compared to 70% alcohol and normal saline. Methods : The effect of skin disinfection was evaluated in newborn infants who were admitted to the neonatal intensive care unit(NICU) of Hanyang University Kuri Hospital by a skin swab culture before and after disinfectant exposure. Before skin disinfective preparation, the peripheral intravenous catheter insertion sites were swabbed for culture with sterile cotton moistened with normal saline. Cotton balls of 70% alcohol(Alcohol group, n=20) or 10% povidone and 70% alcohol(povidone group, n=20) were randomly selected. Normal saline swabs were used for controls(n=10). After swabbing, the skin swab culture was done on same sites with same procedure. Results : Before skin disinfection, culture-positivity was shown in 9 of 20 leases of alcohol and povidone groups, respectively and in 8 of 10 cases of the controls. After skin disinfection, culture-positivity was still shown in 3 of 9 cases of the Alcohol group, in 2 of 9 of the Povidone group, and in 6 of 8 cases of the controls. Disinfective effect was significantly different among the 3 groups(p=0.0387). The povidone group had significantly better disinfection than the controls(p=0.0156), but the alcohol group was not significantly different from the controls. Conclusion : The cotton balls of povidone had similar effect of disinfection compared to those of alcohol, but better disinfection than the controls. A disinfective effect of the cotton balls of alcohol was not, however, significantly different from the controls. We suggest that purity of alcohol, quality control of cotton balls of alcohol, and disinfection method should be reevaluated.

• Journal of the East Asian Society of Dietary Life
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• v.14 no.3
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• pp.207-216
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• 2004

This study was performed in oder to investigate to dietary behavior, perceived stress and their correlations of University students. The number of subjects was 549 and the results of this study are as followed: Only 13.9% of students-20% of male students, 10% of female students-exercise regularly. Regular exercise and health condition had no statistical relationship in this study. 83.9% of subjects had experience of alcohol drinking (19.4% of male students, 7.3% of female students). Many students replied that they drink alcohol 1∼2 times per a week. 24.4% of students-only 2.6% of female students-were smoking and great number of smokers were drinking also. The BMI of 46.7% of subjects were in normal range. 48.2% were in under weighted and 5.1% were in over weighted or obesity. The stress factor of University students were analyzed into 12. Inner stress factors like as identity, coursework, friendship, health problem were more potent in female students than male. Among the health related habits, disease itself had a great effect on many stress factors but regular exercise had a little.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.4
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• pp.347-357
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• 2013

Drug abuse has become a major social problem of the modern world and majority of these abusive drugs or their metabolites are excreted through the kidneys and, thus, the renal complications of these drugs are very common. Morphine, heroin, cocaine, nicotine and alcohol are the most commonly abused drugs, and their use is associated with various types of renal toxicity. The renal complications include a wide range of glomerular, interstitial and vascular diseases leading to acute or chronic renal failure. The present review discusses the renal toxicity profile and possible mechanisms of commonly abused drugs including morphine, heroin, cocaine, nicotine, caffeine and alcohol.

• Journal of the Korean Home Economics Association
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• v.36 no.10
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• pp.103-118
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• 1998

Although there is a little concern about wife beating, the problem is in very serious level. Especially many community workers in urban poor areas reported that they often wittnessed wife abuse cases and most battered women have no place to ask help. However, there is not many systematic analysis on wife abuse in those areas. The purpose of this study are (1) to more accurately estimate the incidence of wife abuse in poor families; (2) to examine the interrelationships of socio economic status, stress and alcohol consumption of wife abuse. The results show that almost 1 out of 3 husbands in urban poor areas carried out 1 or more physical violence acts against their wives during the last year and that social stress has statistically significant relationship with wife abuse in the urban poor families.

• International Journal of Advanced Culture Technology
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• v.7 no.3
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• pp.103-110
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• 2019

The purpose of this study was to investigate the relationship between psychosocial factors, such as self-esteem, stress coping, and social support, and motivation for change in alcohol dependent inpatients. This study included 179 inpatients in the 7clinics for alcoholic in Chonbuk. For the analysis of the study questions, this study utilized the structural equation modeling. The results show that self-esteem was related to motivation for change with mediating role of problem-focused stress coping strategy in alcohol dependent inpatients. The study also reveal that self-esteem and social support was directly associated with the motivation for change. Based on the findings, the importance of programs to promote self-esteem and the involvement of family and acquaintances in the treatment process has been suggested.

• Research in Community and Public Health Nursing
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• v.15 no.3
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• pp.471-482
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• 2004

Purpose: This study intended to identify personality factors and related problematic behaviors of adolescents who drink alcohol in order to provide basic data for developing nursing programs. Methods: The data were collected from October to December 2002 from 1.080 high school students in Seoul. The Revised Cloninger's Tri-dimensional Personality Questionnaire (TPQ) was used to measure their personalities. The alcohol expectancy was measured using the tool revised by Cho (1999) and stress levels were measure using a stress tool revised Cho (1998). The data were analyzed with SPSS Windows using Chi square test. independent t-test. and logistic regression analysis. Results: 1. The percentage of fathers who drank was 79.8%. mothers. 54.3%. and friends. 54.3%. The alcohol expectancy averaged 6.36 while the stress levels were 132.79. 2. It was found that there are significant differences (p<.001) in problematic drinking behaviors according to the following variables: second year high school students among all grade variables, more monthly pocket money for the amount of money variables, the group of students who smoked in the case of the variable related to smoking, spending more time using the Internet for the Internet use variable, and having friends who drink 65.6% for the friend variable. The alcohol expectancy scale of those students who showed problematic drinking behaviors was higher than that of those who did not. There are four family-related stress subscales, and there was a significant difference among them (p<.05). Among the personal characteristics, the group who displayed problematic drinking behaviors seeks new experiences and reward dependence more than the group who did not exhibit those behaviors, and there were significant differences between the two groups (p<.001). 3. When the socio-demographic and drinking-related factors were controlled, the tendency of seeking new experiences increased the risk of problematic behaviors 1.07 times (p<.05). Compared to the non smoking group, the smoking group was found to have a 5.06 time (p<.001) greater risk of displaying problematic drinking behaviors. In comparison with the non drinking group, the drinking group was also found to have a 5.31 time (p<.001) greater risk of exhibiting problematic drinking behaviors. The group with high alcohol expectancy scores was significantly different from the group with the no alcohol expectancy, showing a 1.26 time (p<.00l) greater risk of problematic drinking behaviors. Conclusions: Based on these results, the problematic drinking behaviors were connected with alcohol expectancies, friends and personality types. Therefore, we should develop an alcoholic prevention program for adolescence considering the above results.

• Korean Journal of Social Welfare
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• v.55
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• pp.83-102
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• 2003

The purpose of this study is to investigate the drinking behaviors of adult mentally retarded persons(N=140) over the age of 18. It was also investigated whether gender, age, and pattern of employment create different result of drinking behaviors, whether there is correlation between variables associated with drinking behaviors for mentally retarded persons. 58.2 percent of respondent reported that they had consumed alcohol beverages sometimes prior to their having been interviewed. Average age of respondents who had consumed alcohol was 26.357 years and average age of first-use of alcohol was 22 years. 39.2 percent of respondent reported that they drink alcohol once a month. Beer(54.2 percent) was the most frequently consumed alcohol beverages. Average alcohol consumption per occasion was 1.494 cup, and 10.9 percent of respondent answered more than 5 cups per occasion. Regarding problems associated with drinking, 16 percent of respondent of AUDIT and 51.4 percent of Family CAGE answered that their children have drinking-related problems. Men(64.2 percent) drink more than women(43.6 percent) and experience more alcohol problem. Regarding drinking behaviors associated with the pattern of employment, supervised employment group(78.6 percent) was known as the most prevalent group of experiencing drinking. For the amount of drinking, gender(p<.05) and pattern of employment(p<.05) had shown the significant differences. There were significant positive correlation between the frequency of drinking and the amount of drinking, and AUDIT and Family CAGE.

• Journal of the Korean Applied Science and Technology
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• v.36 no.2
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• pp.572-580
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• 2019

Recently, it has been reported that benzyl alcohol (BzOH) as an additive in cosmetics, food, and medicine lead to toxicity and allergy problem. Then, to circumvent this hurdle, we carried out the synthesis of benzyl alcohol galactoside (BzO-gal). Previously, it was confirmed that BzO-gal was synthesized by transgalactosylation reaction using Escherichia coli (E. coli) ${\beta}$-galactosidase (${\beta}-gal$). Meanwhile, in this study, two peaks of BzO-gal as sodium adduct ion (m/z=293.1004) and protonated ion (m/z=271.1180) were detected in the reaction mixture by liquid chromatography/electrospray ionization mass spectrometry (LC/ESI-MS). In addition, the amount of ${\beta}-gal$ and BzOH concentration, temperature, pH, and lactose concentration, respectively, were optimized (${\beta}-gal$, 0.75 U/mL; BzOH, 185 mM; temperature, $40^{\circ}C$, pH, 7.5; lactose, 350 g/l). Under these optimal conditions, 185 mM BzOH was converted into about 131 mM BzO-gal, in which the conversion yield was about 72%. In the future, BzO-gal will be applicable as a substitute for BzOH as a less toxic preservative for the cosmetic, pharmaceutical, and food industries, and we are planning to investigate the characteristics of BzO-gal as a preservative.

• Nutrition Research and Practice
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• v.14 no.4
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• pp.299-308
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• 2020

BACKGROUND/OBJECTIVES: Heavy alcohol consumption causes the development of alcoholic liver disease (ALD), a neglected but important public health problem. Many studies have pointed out that probiotics could improve gut health, which is also considered to be a cause of ALD. Therefore, this study screened the probiotics, Lactobacillus casei GKC1 (GKC1), L. fermentum GKF3 (GKF3), Bifidobacterium lactis GKK2 (GKK2), L. rhamnosus GKLC1 (GKLC1), L. paracasei GKS6 (GKS6), and L. plantarum GKM3 (GKM3), for their potential benefits in alleviating ALD for applications to disease prevention. SUBJECTS/METHODS: C57BL/6N mice were divided into 8 groups (n = 6 in each): normal control, positive control (alcohol-diet fed), and treatments of feeding probiotics GKC1, GKF3, GKK2, GKLC1, GKS6, and GKM3 under an oral dose 0.82 g/kg B.W. per day by oral gavage. The experiment was conducted for 8 weeks, and the concentrations of alanine aminotransferase (ALT), aspartate aminotransferase, triglyceride (TG), and total cholesterol (TC) in mice were measured. The glutathione (GSH), catalase (CAT), and histology were analyzed after sacrifice. RESULTS: The results showed a decrease in the serum ALT, liver TG, and liver TC levels in the GKS6, GKM3, and GKLC1 groups compared to the positive control. In addition, the decreasing GSH and CAT levels were inhibited in the GKS6 and GKM3 groups. The histopathological results showed that all probiotics could reduce the accumulation of liver fat. Furthermore, there was a significant difference in GKLC1 with lower stomach damage compared to the alcohol-fed mice without any addition of probiotics. CONCLUSIONS: GKLC1, GKS6, and GKM3 can be used as supplements for alleviating the development of ALD.