• Microbiology and Biotechnology Letters
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• v.34 no.3
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• pp.216-220
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• 2006

Thermophillic fungus Thermoascus aurantiacus showed excellent growth and produced high amount of alcohol oxidase and catalase in a pectin medium. Besides, the strain produced enzymes which related with pectin or alcohol decomposition. We detected extracellular pectin esterase (EC 3.1.1.11) activity and, both intracellular and extracellular pectinase (EC 4.2.2.10) activity, as pectinolytic enzymes produced by T. aurantiacus. The production of methanol decomposition enzymes, such as alcohol oxidase (AOD, EC 1.1.3.13), alcohol dehydrogenase (ADH, EC 1.1.1.1), formaldehyde dehydrogenase (FADH, EC 1.2.1.1) and formate dehydrogenase (FDH, EC 1.2.1.2) follows by pectin esterase reaction which is converted to methanol. We concluded that T. aurantiacus has pectinolytic and alcohol - oxidative enzymological mechanism which produced carbon dioxide as a final material, started from pectin.

• Journal of the Korean Society of Food Culture
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• v.26 no.2
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• pp.101-112
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• 2011

The objective of this study was to examine alcohol consumption rates and the perception of drinking cultures among college students in the Wonju area. An examination of factors such as frequency of drinking, average quantity consumed, and frequency of heavy drinking suggested that the drinking rates were relatively high. Over 70% of subjects drank at least once a week, 66.2% typically drank more than 5 servings at a time, and 19.2% of males and 13.0% of females were heavy drinkers. It was revealed from an AUDIT (Alcohol Use Disorder Identification Test) assessment that 71.3% of the subjects tested had various levels of alcohol-related problems. These problems were more severe in subjects that were male, selfboarding, or overweight. Alcohol related knowledge was not high because the subjects didn't know or incorrectly recognized some contents such as blood alcohol concentration, the energy content of alcohol, and the empty caloric characteristics of alcohol. Generally male, self-boarding, and overweight persons were not critical of the undesirable characteristics associated with drinking culture. Two opinions that were generally considered to be permissible were: 'Men should be able to drink' and 'Drinking is essential for a smooth human relationship'.

• Food Science and Biotechnology
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• v.17 no.6
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• pp.1207-1213
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• 2008

The possible protective effects of highly zinc-containing yeast Saccharomyces cerevisiae, FF-10 strain, isolated from tropical fruit rambutan on acute alcoholic liver injury in rats were evaluated. Zinc concentration in this strain was 30.6mg%. The activities of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and $\gamma$-glutamyl transpeptidase ($\gamma$-GTP) were highly increased when alcohol was treated, relative to the normal rats. Also, a highly significant increase in the blood alcohol and acetaldehyde levels by alcohol treatment was observed. Administration of FF-10 strain markedly prevented alcohol-induced elevation of the activities of serum ALT, AST, and $\gamma$-GTP, and the levels of blood alcohol and acetaldehyde, and these reduced levels reached to that of normal rats. As compared with alcohol treated control rats, the FF-10 strain supplementation showed highly decreased the triglyceride concentration in serum. Alcohol treatment induced the marked accumulation of small lipid droplets, hepatocytes necrosis, and inflammation, but FF-10 strain administration attenuated to alcohol-induced accumulation of small lipid droplets and hepatocyte necrosis in the liver. Therefore, the current finding suggests that zinc-enriched yeast FF-10 strain isolated from tropical fruit rambutan may have protective effect against alcohol-induced hepatotoxicity.

• Journal of Korean Public Health Nursing
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• v.23 no.1
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• pp.17-26
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• 2009

Purpose: In this study, the effects of an alcohol education program for elderly persons with drinking problems and the effects of knowledge of the behavior associated with alcohol use by elderly individuals with drinking problems were evaluated. Method: A single-group repeated study was conducted to evaluate 19 elderly individuals with drinking problems who used the G-city Elderly Welfare Center, with more than eight points in AUDIT results. The changes in drinking knowledge and alcohol behavior following an alcohol education program were evaluated. The effectiveness of the program was analyzed by a Wilcoxon signed rank test. and the relationship between drinking knowledge and changes in alcohol behavior was measured by Spearman's rank correlation coefficient. Results: The results indicated that drinking knowledge after conducting education increased significantly(Z=-3.826, p<.001), and that this increased knowledge resulted in significant changes in alcohol behavior(Z=-3.830, p<.001). There was a significantly positive relationship between drinking knowledge and changes in alcohol behavior(r=.464, p=0.013). Conclusion: Alcohol education programs effectively educate the elderly with drinking problems regarding alcohol, which influences their alcohol behavior.

• Korean Journal of Biological Psychiatry
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• v.10 no.2
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• pp.159-167
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• 2003

Objective:Under the hypothesis that 5-HTTLPR polymorphism plays some role in the susceptibility or vulnerability of some subgroup of alcohol dependence, associations of 5-HTTLPR polymorphism with alcohol dependence were examined. Method:This association analysis included 109 Korean alcohol dependent and 113 Korean control subjects. DNA of all subjects were genotyped for the biallelic functional polymorphism in the 5-HTTLPR. Considering the likelihood of heterogeneity in the alcohol dependence phenotype, alcohol dependent subjects were subgrouped by onset age, family history of alcohol dependence and severity of withdrawal symptoms. Results:There were no significant differences in the frequencies of either the 5-HTTLPR genotype or the short vs. long allele in alcohol dependent and control subjects. The frequency of the S allele and S-carrier (LS or SS genotype) was significantly increased in the early onset alcohol dependent subjects and the familial alcohol dependent subjects compared with that in the control subjects. Conclusion:The results suggest that the 5-HTT 'S' promoter polymorphism is associated with an increased susceptibility or vulnerability to develop early onset alcohol dependence and familial alcohol dependence, which characterize Cloninger's type 2 alcohol dependence.

• Korean Journal of Occupational Health Nursing
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• v.9 no.2
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• pp.132-142
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• 2000

This paper tried to understand the effects of alcohol-reducing program on drinkings behaviour of workers on works under 5 employees. For these, this paper understood a change of drinkings custom and degree of alcohol-reducing strategy practice by enforcement of alcohol reducing program over 7 times during 3 months Reaults from analyses are as follows 1) A health problems related to drinkings were a chronic fatigue and indigestion, 15.5% was over 5 items among items related to liver disease. 2) The subjector of investigation all was involved over 2 items among items that a drinking custom must be collecred. 3) The change of drinkings custom between before and after on enforcement of alcohol reducing program showed a effective difference. 4) For a degree of the alcohol-reducing strategy practice, "reducing drinkings days" was 82.9%. "bearing drinkings impulse" 70.7%, "exchanging drinkings custom" 56.1%, "avoiding drinkings friends" 51.2%, Yet, "avoiding drinking place" and "preparing leisure activity to exchange drinkings" showed a low practice ratio. 5) For correlation between drinkings drinkings behaviour and degree of alcohol-reducing strategy practice, the more drinkings times before program paticipatance the higher alcohol-reducing strategy practice, alcohol dependency and drinkings times, alcohol-reducing strategy and drinkings times, befere drinking custom had an effective negative corelation, after drinkings custom and alcohol-reducing strategy a strong effective positive corelation. 6) workers writing drinkings paper decreased drinkings times. Implications from results are as follows The alcohol-reducing program is necessary to works under 5 employees, and needs to he operated continously. Especially, in works under 5 emplyees, the alcohol-reducing programt needs to be operated by firm or government.

• Journal of the Korean Dietetic Association
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• v.7 no.3
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• pp.267-273
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• 2001

The purpose of this study was to investigate the relationship between alcohol consumption and nutritional status of university male freshman in Chungnam area. The total of 111 subjects took part in the study and, they were observed general characteristics, alcohol consumption status, and nutrient intake using questionnaires. The mean age, height, weight, and BMI of the subjects were 19.3 years, 174.3㎝, 65.2㎏, and 21.5㎏/$m^2$ respectively. The mean alcohol consumption, and energy intake from alcohol were 7.8g/day, 55.3kcal/day. A significant number of subjects(48.2%) answered their frequency of alcohol consumption was once 2 weeks. Only 4.6% of subjects answered never drink. In almost subjects, alcohol consumption have been stared since they were adolescents, and major type of alcoholic beverage was 'soju'. The mean energy intake was 1985.6kcal and, energy ratio from carbohydrate, protein, fat was 58 : 15 : 27. There were significantly positive correlation among alcohol consumption and, body weight(p<0.05), intake of food, (p<0.05), energy(p<0.001), animal fat(p<0.05), fiber(p<0.05), vitamin $B_2$(p<0.05) and niacin(p<0.05). The alcohol consumption period showed a significantly positive correlation with alcohol consumption per one time(p<0.05). In summary, high consumption of alcohol in subjects was observed. Also, increase of alcohol consumption was related to weight gain and nutritional imbalance. Therefore, it is need that nutrition education for prevention of high alcohol consumption in university freshman and adolescents.

• Korean Journal of Health Education and Promotion
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• v.33 no.3
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• pp.49-60
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• 2016

Objectives: This study sought to explore the relationships between drinking problems and alcohol's harm to others with the moderating effects of alcohol expectancies on these relationships after controlling for demographic characteristics. Methods: Participants for this study were 1,859 men and women. We performed hierarchical regression analyses with sets of predictors (1) demographic characteristics, (2) drinking problems and alcohol expectancies, and (3) interaction terms between drinking problems and alcohol expectancies. Results: After controlling for demographic characteristics, drinking problems and alcohol expectancies had the significant effects on alcohol's harm to others in both men and women. However, the interactions between drinking problems and negative alcohol expectancy showed the significant impacts on alcohol's harm to others among men. When men had higher levels of negative alcohol expectancy, drinking problems showed stronger effects on alcohol's harm to others. Conclusions: As a result, findings from the study highlight the importance of more sophisticated public policy to prevent and to intervene drinking problems and to support those around drinkers and drinkers themselves.

• Preventive Nutrition and Food Science
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• v.13 no.3
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• pp.212-218
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• 2008

We extracted red ginseng with various alcohol concentrations and evaluated total carbohydrate, uronic acid, polyphenols compounds and ginsenoside contents, and yields of alcohol extract. The water extraction (0% alcohol extraction) showed a high level of total carbohydrate content. 10% and 20% alcohol extraction showed the highest uronic acid contents (7,978.8 and $7,872.7\;{\mu}g/mL$ of extract, respectively). The efficiency order of the red ginseng extract (RGE) preparations in liberating polyphenols was: $0{\sim}50%$ alcohol${\geq}\;60%$ alcohol> $70{\sim}90%$ alcohol. Solid contents in RGE were decreased with increased alcohol concentration; the same tendency as with the results of total carbohydrate content. Total ginsenoside contents in $20{\sim}50%$ alcohol extracts showed similar levels ($442,962.9{\sim}47,930.8\;{\mu}g/mL$ of extract). Water extraction showed the lowest ginsenoside content ($14,509.4\;{\mu}g/mL$ of extract). The ginsenoside contents at above 60% alcohol were decreased with increased alcohol concentration. Generally, ginsenoside (Rg2, Rg1, Rf, Re, Rd, Rb2, Rc and Rb1) contents were increased with increased alcohol concentrations. However, Rg3 content was decreased with increases in alcohol concentration.

• Korean Journal of Social Welfare
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• v.47
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• pp.71-106
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• 2001

The purposes of this study were to provide information on the prevalence and change of Korean adolescent alcohol use and to identify related factors to adolescent alcohol use. This study collected data from a total of 4,373 adolescents nationally. Followings are the major findings of this study. First, 75.7 percent of respondents reported that they tried alcohol in their life time. More male respondents tried alcohol in their lifetime than female respondents, but there was no big difference. Findings on alcohol consumption by grade showed that as adolescents get older, they are more likely to try alcohol. Second, this study also found that whereas the drinking rates of male adolescents and higher graders were steady, the rates of female adolescents and lower graders were increased since 1997. Third, this study compared its findings with adolescent alcohol use in the United States. Little differences existed in measures of adolescent alcohol use in the two countries, but the differences in the rates of the past-month alcohol use and heavy drinking was greater in Korean adolescents than in American adolescents. Finally, this study found that peer related factors such as friend's alcohol use was the strongest factor related to respondents' alcohol use. Family-related factors and respondents' levels of psychosocial resources (cognitive control, coping skills, social support) were also significantly related to their alcohol use. This study suggest that future studies consider cultural aspects and regional differences in order to understand adolescent alcohol use in more depth.