• 제목/요약/키워드: Ajuga multiflora Bunge

검색결과 4건 처리시간 0.017초

조개나물 추출물의 세포독성과 항균효과 (Studies on the Cytotoxicity and Antimicrobial Effects of the Extract of Ajuga multiflora Bunge)

  • 류명환;엄용대;변종호;조훈;양은영;강길웅;신민교;백승화
    • 생약학회지
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    • 제31권1호
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    • pp.72-76
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    • 2000
  • This study was carried out to evaluate cytotoxic effects of Ajuga multiflora Bunge extracts on murine leukemia tumor $(P388D_1)$ cell lines. Disruptions in cell organelles were determined by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazoliumbromide (MTT) assay. The comparison of $IC_{50}$ values of Ajuga multiflora Bunge extracts in L1210 and $P388D_1$ cell lines showed that their susceptibility to these extracts decreased in the following order: Adriamycin>methanol extract>chloroform extract>ethyl acetate extract>hexane extract>water extract by the MTT assay. In order to develop an antimicrobial agent, dried Ajuga multiflora Bunge was extracted with several solvents, and then antimicrobial activity was investigated. The minimal inhibitory concentration (MIC) of the extract against microorganisms were also examined. Antimicrobial activities of amocla and ketoconazole as references were compared to those of extracts of $H_2O$, n-hexane, chloroform, ethyl acetate and methanol. The antimicrobial activity of all extracts from the sample had growth inhibition activity against gram-negative bacteria, gram-positive bacteria and fungi $(MIC>200\;{\mu}g/ml)$. These results suggest that the methanol soluble extract of Ajuga multiflora Bunge may be a valuable choice for the studies on the treatment of murine leukemia tumor cell lines.

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이리도이드 배당체(配糖體)(VI) -조개나물의 이리도이드 배당체- (Iridoid Glycoside(VI) -Studies on the Iridoid Glycoside of Ajuga multiflora Bunge-)

  • 정보섭;유완근
    • 생약학회지
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    • 제16권3호
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    • pp.160-164
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    • 1985
  • Ajuga multiflora Bunge is a perennial herb in the family of Labiatae. The iridoid glycoside was isolated from the ethylacetate fraction and the n-butanol fraction of the plant. The structure of the substance was identified as 8-O-acetylharpagide by UV, IR, NMR spectra and several chemical reactions.

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경상북도 경주시 금곡산에 분포하는 관속식물상 (Flora Distributed in Mt. Geumgok, Gyeongju-si, Gyeongsangbuk-do)

  • 유주한
    • 한국자원식물학회지
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    • 제26권2호
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    • pp.248-270
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    • 2013
  • 본 연구는 경상북도 경주시에 위치한 금곡산의 관속식물상을 조사 및 분석함으로서 식물생태계의 보전을 위한 기초 자료 수집에 목적이 있다. 금곡산의 관속식물은 91과 298속 397종 4아종 46변종 6품종 등 총 453분류군으로 요약되었다. 산림청 지정 희귀식물은 변산바람꽃, 솜양지꽃, 노랑무늬붓꽃 등 3분류군으로 나타났다. 한국특산식물은 서어나무, 변산바람꽃, 고광나무, 해변싸리, 노랑갈퀴, 병꽃나무 등 6분류군으로 확인되었다. 식물구계학적 특정식물은 잣나무, 왕버들, 꿩의바람꽃, 홀아비꽃대, 대극, 대팻집나무, 조개나물, 빗살서덜취, 노랑제비꽃, 물박달나무, 좀목형, 승마 등 36분류군으로 나타났다. 귀화식물은 닭의덩굴, 다닥냉이, 아까시나무, 토끼풀, 애기땅빈대, 둥근잎나팔꽃, 큰개불알풀, 울산도깨비바늘, 지느러미엉겅퀴, 큰도꼬마리, 큰이삭풀, 큰김의털 등 36분류군이 확인되었다. 생태계교란야생동식물은 돼지풀, 미국쑥부쟁이 등 2분류 군이었다. 도시화지수(UI)는 11.2%, 귀화율(NI)은 7.9%, 교란율(DI)은 18.2%로 분석되었다.