• Title/Summary/Keyword: Air trapping

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A Case of Venlafaxine-Induced Interstitial Lung Disease

  • Oh, Serim;Cha, Seung-Ick;Kim, Hyera;Kim, Minjung;Choi, Sun Ha;Seo, Hyewon;Park, Tae-In
    • Tuberculosis and Respiratory Diseases
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    • v.77 no.2
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    • pp.81-84
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    • 2014
  • A patient treated with venlafaxine for major depression developed an interstitial lung disease (ILD) with the characteristic clinical, radiological and pathological features of chronic hypersensitivity pneumonitis. A high resolution computed tomography scan demonstrated ground glass opacity, mosaic perfusion with air-trapping and traction bronchiectasis in both lungs. The pathological findings were consistent with a nonspecific interstitial pneumonia pattern. Clinical and radiological improvements were noted after the discontinuation of venlafaxine and the administration of a corticosteroid. This report provides further evidence that the anti-depressant venlafaxine can cause ILD.

High-resolution computed tomography findings of lung parenchyme changes in very low birth weight infants treated with oxygen (산소 치료를 받은 극소저출생 체중아에서 폐 실질변화에 관한 고해상컴퓨터 단층촬영술 소견에 관한 연구)

  • Jin, Young Man;Chung, David Chanwook;Chang, Young Pyo;Lee, Yung Suk;Lee, En Sun
    • Clinical and Experimental Pediatrics
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    • v.50 no.3
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    • pp.255-261
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    • 2007
  • Purpose : The objective of this study is to observe high-resolution computed tomography (HRCT) findings of lung parenchyme in very low birth weight (VLBW) infants between the corrected age of 38-42 weeks who were treated with oxygen after birth, and to compare them to the clinical severity of bronchopulmonary dysplasia (BPD). Methods : The lungs of fourty-four VLBW infants with gestational ages of less than 32 weeks and birth weights of less than 1,500 g who were treated with oxygen after birth were examined using HRCT taken when the corrected age was between 38-42 weeks. Common findings among the infants and the frequency of their occurrences were noted. Total CT scores obtained by the summation of air trapping and actelectasis scores and the ratio of bronchus-to-pulmonary artery diameter were used to quantitatively evaluate HRCT findings and correlate them with the clinical severity of BPD as defined by Jobe-Bancalari diagnostic criteria. Results : 1) The most common findings in HRCT images of the lungs were air trapping (56%), atelectasis (70.5%), linear opacity (77%), and distortion of the bronchopulmonary bundle (65.9%). These findings were more commonly observed in infants with BPD in a mixed pattern than those without (P<0.05). However, abnormal findings were also found in HRCT images of some infants without BPD. In infants with BPD, air trapping, atelectasis and total CT scores were higher than those without BPD. Also infants with BPD had a lower bronchus-to-pulmonary artery diameter than those without BPD (P<0.05). 2) The total CT scores (r=0.799, P<0.0001) and the ratio of bronchus-to-pulmonary artery diameter (r=0.576, P<0.0001) showed a linear correlation with the clinical severity of BPD. Conclusion : HRCT findings in VLBW infants between the corrected age of 38-42 weeks who had been treated with oxygen after birth are useful in revealing pathologic changes in the lung parenchyme and show a good correlation with the clinical severity of BPD.

Clinical Significance of Airway Resistance Curve by the Body Plethysmograph (Body Plethysmograph를 이용한 Airway Resistance Curve의 임상적 의의)

  • Cheon, Seon-Hee
    • Tuberculosis and Respiratory Diseases
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    • v.42 no.2
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    • pp.218-225
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    • 1995
  • Background: Airway resistance(Raw) is measured with the body plethysmograph by displaying the relationship between airflow and alveolar pressure($V/P_A$). If the resistance curve on $V/P_A$ tracing is curved or looped, the estimation of Raw is difficult. This study was designed to examine wheather there is any correlation between the shape of resistance curve and the clinical status and the pulmonary function of patients. Methods: The 146 pulmonary disease patients with increased Raw were included in this study. The shapes of resistance curves on $V/P_A$ tracing with body plethysmograph during quiet breathing were analyzed and compared with pulmonary function. Results: The results were as follows ; 1) The shapes of resistance curves were summarized in 5 categories; type 1: linear, type 2: ovoid, type 3: sigmoid, type 4: scoop, type 5: paisley. The type 3 except 1 case, type 4 and type 5 were found to have loop mainly in expiratory phase. 2) Although the shapes of resistance curves were not typical for specific disease, the resistance curves of acute disease tended to belong to type 1 or 2 and those of chronic airflow obstruction tended to belong to type 3, 4 or 5. But resistance curves of bronchial asthma and destructive lung with tuberculosis showed all types in proportion to degree of airflow obstruction or destruction of parenchyme. 3) In the cases of resistance curves going to type 5 rather than type 1 and those with looping, airflow obstuction tended to be severe and airway resistance and residual volume tended to increase. Conclusions: Analysis of resistance curve on $V/P_A$ tracing measuring airway resistance is helpful for judging degree of airflow obstruction and air trapping. Although the shape of resistance curve is not typical for specific disease, there is a close association between looping and airway obstruction.

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Forecasting the Pepper Gray Mold Rot to Predict the Initial Infection by Botrytis cinerea in Greenhouse Conditions

  • Park, Seon-Hee;Lee, Joon-Taek;Chung, Sung-Ok;Kim, Hee-Kyu
    • The Plant Pathology Journal
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    • v.15 no.4
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    • pp.158-161
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    • 1999
  • We determined threshold environmental factros to initiate infection of pepper plants by Botrytis cinerea, a fungal pathogen of pepper gray mold, in two greenhouse conditions. A new efficient spore-trapping method was developed to estimate population density of airborne conidia in the greenhouses, and spore release was measured using a Kerssies' selective medium. At a given day, spores were released greater during daytime (mostly from 7:30 am to 10:30 am and at 4:30 pm) than nighttime. Diurnal and nocturnal temperatures in the greenhouse-1 were about $25^{\circ}$ and $17^{\circ}$,and relative humidity was 100% for prolonged 24 h due to rain on December 17, 1997. Population density of air-borne conidia was 3.0$\times$103 conidia/ $0.5\textrm{m}^3$ after two days, and the initial infection occurred in ten days. During the same period of time in the greenhouse-2, diurnal temperature was about $25^{\circ}$ and nocturnal temperature was below $15^{\circ}$, and population density of air-borne conidia was 104 conidia/ $0.5\textrm{m}^3$. Under these conditions, the initial infection started in three days. This indicates that the early infection occurs under which diurnal temperature is approximately $25^{\circ}$, nocturnal temperature is maintained below $15^{\circ}$, and population density of air-borne conidia is 104 conidia/ $0.5\textrm{m}^3$ at saturated relative humidity condition.

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Effect of Particle Size and Unburned Carbon Content of Fly Ash from Hadong Power Plant on Compressive Strength of Geopolymers (하동화력발전소 비산재의 입도크기와 미연탄소 함량이 지오폴리머의 압축강도에 미치는 영향)

  • Kang, Nam-Hee;Chon, Chul-Min;Jou, Hyeong-Tae;Lee, Sujeong
    • Korean Journal of Materials Research
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    • v.23 no.9
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    • pp.510-516
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    • 2013
  • Fly ash is one of the aluminosilicate sources used for the synthesis of geopolymers. The particle size distribution of fly ash and the content of unburned carbon residue are known to affect the compressive strength of geopolymers. In this study, the effects of particle size and unburned carbon content of fly ash on the compressive strength of geopolymers have been studied over a compositional range in geopolymer gels. Unburned carbon was effectively separated in the $-46{\mu}m$ fraction using an air classifier and the fixed carbon content declined from 3.04 wt% to 0.06 wt%. The mean particle size ($d_{50}$) decreased from $22.17{\mu}m$ to $10.79{\mu}m$. Size separation of fly ash by air classification resulted in reduced particle size and carbon residue content with a collateral increase in reactivity with alkali activators. Geopolymers produced from carbon-free ash, which was separated by air classification, developed up to 50 % higher compressive strength compared to geopolymers synthesized from raw ash. It was presumed that porous carbon particles hinder geopolymerization by trapping vitreous spheres in the pores of carbon particles and allowing them to remain intact in spite of alkaline attack. The microstructure of the geopolymers did not vary considerably with compressive strength, but the highest connectivity of the geopolymer gel network was achieved when the Si/Al ratio of the geopolymer gel was 5.0.

Bronchogenic cysts treated with the transcervical approach (경부절게를 통한 기관지원성낭종 치료)

  • Song, Jong Hoon;Hong, Ki Hwan;Hong, Yong Tae;Kim, Eun Ji
    • Korean Journal of Head & Neck Oncology
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    • v.33 no.2
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    • pp.75-79
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    • 2017
  • Bronchogenic cysts are congenital malformations of the bronchial tree, a type of bronchopulmonary foregut malformation. The presentation of the bronchogenic cyst is variable, making pre-operative diagnosis difficult. They aremostly asymptomatic orarefound incidentally when the chest is imaged. They can present as lower neck massesor mediastinal masses that may enlarge. They cause mass effect due to local compression and may result in tracheo-bronchial obstruction leading to air trapping and respiratory distress. The treatment is somewhat controversial, and in general,these lesions are treated using the transcervical or transbronchial approach. When these cysts arelocalized in the upper mediastinum, it may be possible to removethemusing the transcervical approach. In our three cases, the patientscomplained of mild dysphagia, foreign body sensation, and dyspnea. We report three cases of a large bronchogenic cyst in the lower neck and the upper mediastinum treated using the transcervical approach.

Study on Effects of Foam-Filter for Reduction of Air-Trapping in Large-Size Sand Gravity Casting (대형 중력주물품의 기공발생 저감을 위한 다공성 필터 (Foam-Filter) 적용효과 분석)

  • Yu, Jae Hyun;Lee, Ho Rim;Joo, Jeong A;Hwang, Yun Je;Shin, Bo Sung;Park, Sang Hu
    • Journal of the Korean Society for Precision Engineering
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    • v.33 no.6
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    • pp.469-475
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    • 2016
  • In this work, casting processes, such as filling and solidification, were simulated in order to accurately predict volume shrinkage defects in large-sized sand gravity casting. Turbulent flow of melted materials and a difference of solidification speed can cause volume shrinkage defects. In order to solve this problem and to understand the phenomenon, a porous filter application was studied. Two different porosities of 10 and 20 p.p.i filters were introduced into the gating system, and in view of the results so far achieved, the defect was dramatically reduced by 22%, compared to that without the use of the filter.

Studies on the Correlation between Coated Paper and Physical Properties of Latices (라덱스의 물성이 도공지 품질에 미치는 상관성에 대한 연구)

  • 박동국;조교동;고문찬;윤재한;이용규
    • Journal of Korea Technical Association of The Pulp and Paper Industry
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    • v.34 no.1
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    • pp.22-29
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    • 2002
  • The coated paper was greatly affected by the basic physical properties of the binder as well as the amount of the coating formula. High glass transition temperature (Tg) of the styrene-butadiene (SB) latex, selected as the binder in our study, gave the high stiffness to the coated paper, but lowered the binding force and print gloss. The average particle size of the SB latex also greatly affected to the coated paper so that the smaller particle size improved the rheological property of the coating formula and increased the binding force and print gloss. Another property of the SBR latex, gel content, was important because when its value was small, the latex was easily deformed at the high temperature and increased air permeability to the coated paper. Therefore, the lower gel content consequently resulted in the higher blistering resistance, especially in the web paper. The larger portion of the SB latex in the coated formula improved the binding force and print gloss, but decreased the ink set-off and ink-trapping to the coated paper. The heavier coating improved optical properties such as opacity, paper gloss and paper smoothness, to the coated paper.

Postinfectious bronchiolitis obliterans in children: lessons from bronchiolitis obliterans after lung transplantation and hematopoietic stem cell transplantation

  • Yu, Jinho
    • Clinical and Experimental Pediatrics
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    • v.58 no.12
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    • pp.459-465
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    • 2015
  • Postinfectious bronchiolitis obliterans (PIBO) is an irreversible obstructive lung disease characterized by subepithelial inflammation and fibrotic narrowing of the bronchioles after lower respiratory tract infection during childhood, especially early childhood. Although diagnosis of PIBO should be confirmed by histopathology, it is generally based on history and clinical findings. Irreversible airway obstruction is demonstrated by decreased forced expiratory volume in 1 second with an absent bronchodilator response, and by mosaic perfusion, air trapping, and/or bronchiectasis on computed tomography images. However, lung function tests using spirometry are not feasible in young children, and most cases of PIBO develop during early childhood. Further studies focused on obtaining serial measurements of lung function in infants and toddlers with a risk of bronchiolitis obliterans (BO) after lower respiratory tract infection are therefore needed. Although an optimal treatment for PIBO has not been established, corticosteroids have been used to target the inflammatory component. Other treatment modalities for BO after lung transplantation or hematopoietic stem cell transplantation have been studied in clinical trials, and the results can be extrapolated for the treatment of PIBO. Lung transplantation remains the final option for children with PIBO who have progressed to end-stage lung disease.

Solution-processible corrugated structure and scattering layer for enhanced light extraction from organic light-emitting diodes

  • Hyun, Woo Jin;Im, Sang Hyuk;Park, O Ok;Chin, Byung Doo
    • Journal of Information Display
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    • v.13 no.4
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    • pp.151-157
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    • 2012
  • A simple method of fabricating out-coupling structures was demonstrated via solution-processing to enhance light extraction from organic light-emitting diodes (OLEDs). Scattering layers were easily obtained by spin-coating an $SiO_2$ sol solution that contained $TiO_2$ particles. By introducing the scattering layer and the solution-processible corrugated structure as internal and external extraction layers, the OLEDs showed increased external quantum efficiency without a change in the electroluminescence spectrum compared to conventional devices. Using these solution-processible out-coupling structures, nearly all-solution-processed OLEDs with enhanced light extraction could be fabricated. The light extraction enhancement is attributed to the suppression by the out-coupling structures of the light-trapping that arose at the interface of the glass substrate and the air.