• Journal of Pharmaceutical Investigation
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• v.32 no.1
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• pp.21-26
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• 2002

The primary culture of human nasal epithelial cell monolayer was performed on a Transwell. The effect of various factors on the tight junction formation was observed in order to develop an in vitro experimental system for nasal transport studies. Human nasal epithelial cells, collected from human normal inferior turbinates, were plated onto diverse inserts. After 4 days, media of the apical surface was removed for air-liquid interface (ALI) culture. Morphological characteristics was observed by transmission electron microscopy (TEM). A polyester membrane of $0.4\;{\mu}m$ pore size was determined as the most effective insert based on the change in the transepithelial electric resistance (TEER) value as well as the $^{14}C-mannitol$ transport study. The ALI method was effective in developing the tight junction as observed in the further increase in the TEER value and reduction in the permeability coefficient $(P_{app})$ of $^{14}C-mannitol$ transport. Results of the transport study of a model drug, budesonide, showed that the primary culture system developed in this study could be further developed and applied for in vitro nasal transport studies.

• The Korean Journal of Air & Space Law and Policy
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• v.25 no.2
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• pp.3-42
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• 2010

This study shows that the Warsaw Convention in Article 1 is not an international transport, origin, destination and all the Contracting Parties is not a purely domestic shipping does not apply to this Treaty. Therefore, in this case, liability and damages for the governing law is selected according to international law should be. In addition, in the case of international shipping and passenger air carrier of this treaty to govern the relationship, not all of which aim is the unification of certain rules. Product liability is the most important thing of all. As for the aircraft manufacturer's responsibility according to international law also does not select the applicable law is not. The Warsaw Convention Article 17 apply for the passenger's personal damages Article 2 Section 2 leads to the most prestigious type of damages, and subjective and objective with regard to the scope of international law are being committed. In this regard, Governing Law-related aircraft accidents leading to serious accidents in China of an aircraft crash in Nagoya, Japan, the airport can be. China Airlines accident of the aircraft are operated for the unification of the rules for international air transport on the Warsaw Convention as amended by Article 17, Article 18 of damages by the tort claims and claims based on damages caused by, or this cause of aircraft accidents air bus maker by the Corporation for damages in tort claims for damages claimed on the basis of solidarity is the case. In the case of these grand scale claim responsibility for the airline, air transport agreements to determine the applicable law of the contract is very complex. There for the contracts based on individual circumstances or origin, and by considering because each must be determined.

• Journal of the Korea Safety Management & Science
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• v.10 no.4
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• pp.173-179
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• 2008

The portion of air logistics is getting growing in the global logistics and customer need the rapidity and accuracy for freight delivery. But, the process of air logistics is so complicated because there are too many stakeholders involved in the process. So we suggest the way to make simple the process for improving ability of handling air freights. First, we analyze the AS-IS process and problems by studying previous documents and researching the field. Also we offer how to adopt the ways that are solutions concerning AS-IS process. Second, we suggest integrated information system that will make it simple the air logistics process and mitigate the intensive work load of air cargo. Also we show the reliance about our suggestion by simulation comparing TO-BE process to AS-IS process. We result in that this study will contribute to improve air logistics process by making simple the process.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.22 no.4
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• pp.99-109
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• 2014

Airline and medical industry in Korea have rapidly grown since 21st century. However, air ambulance service using an aircraft has not as popular as in Japan, Europe or United States. Central government has decided to start emergency helicopter service since 2011 to transport emergency patients transported in the past by fire fighter helicopter. Unfortunately, 32 OECD countries out of 33 have operated emergency aircraft system except Korea. There are more than 25 emergency helicopters in Japan, which can operate within five minutes. Such system could save a lot of social direct or in-direct cost by saving valuable lives of Japan citizens. This paper has tried to research the perception of overseas Russian medical tourists on using Air ambulance for their medical tourism to Korea. Researching air ambulance, this paper expects to find ways to enhance both medical tourism industry and airline, business jet industry. According to research results, it was proven that tangibility of medical tourism service has a positive effect on the human factor of air ambulance. The human factor has also a significant impact on the passenger comfortableness of air ambulance. Such comfortableness increases the overall satisfaction of medical tourism.

• Computers and Concrete
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• v.8 no.2
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• pp.177-192
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• 2011

This research paper aims at computer based modeling of carbonation induced corrosion under extreme conditions and its experimental verification by incorporating enhanced electrochemical and mass balance equations based on thermo-hygro physics with strong coupling of mass transport and equilibrium in micro-pore structure of carbonated concrete for which the previous research data is limited. In this paper the carbonation induced electrochemical corrosion model is developed and coupled with carbon dioxide transport computational model by the use of a concrete durability computer based model DuCOM developed by our research group at concrete laboratory in the University of Tokyo and its reliability is checked in the light of experiment results of carbonation induced corrosion mass loss obtained in this research. The comparison of model analysis and experiment results shows a fair agreement. The carbonation induced corrosion model computation reasonably predicts the quantitative behavior of corrosion rate for normal air dry relative humidity conditions. The computational model developed also shows fair qualitative corrosion rate simulation and analysis for various pH levels and coupled environmental actions of chloride and carbonation. Detailed verification of the model for the quantitative carbonation induced corrosion rate computation under varying relative conditions, different pH levels and combined effects of carbonation and chloride attack remain as scope for future research.

• 한국신재생에너지학회:학술대회논문집
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• 2011.05a
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• pp.174.1-174.1
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• 2011

Biogas production and utilisation is an emerging alternative energy technology. Biogas is produced from the biological breakdown of organic matter through anaerobic digestion. Biogas can be utilized for various energy services such as heating, electricity generation and vehicle fuel. Especially, to be utilized as vehicle fuel, raw biogas needs to be upgraded, that is, mainly the removal of carbon dioxide to increase the methane content, up to more than 95% in some cases, similar to the composition of fossil-based natural gas. Biogas fuelled vehicles can reduce $CO_2$ emission by between 75% and 200% compared with fossil fuels. Biomethane development is largely driven by national initiative and predominately by concerns for national air pollution and waste management. Recently, biogas projects for vehicle fuels by some companies are ongoing and Korea government also announced investment to develop biogas as a transport fuel. Therefore, the aim of this study is to examine the feasibility of biomethane as a transport fuel in Korea. In this study, we investigated quality characteristics, quality standard and upgrading technology to use vehicle fuel of transport sector in Korea.

• 한국태양에너지학회:학술대회논문집
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• 2008.11a
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• pp.220-225
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• 2008

Cylindrical stainless-steel/sodium heat pipe for a high-temperature solar thermal application was manufactured and tested for transient and steady-state operations. Two layers of stainless-steel screen mesh wick was inserted as a capillary structure. The outer diameter of the heat pipe was 12.7 mm and the total length was 250 mm. The effective heat transport length, the thermal load, and the operating temperature were varied as thermal transport conditions of the heat pipe. The thermal load was supplied by an electric furnace up to 1kW and the cooling was performed by forced convection of air The effective thermal conductivity and the thermal resistance were investigated as a function of heat flux, heat transport length, and vapor temperature. Typical range of the total effective thermal conductivity was as low as 43,500 W/m K for heat flux of 176.4 kW/$m^2$ and of operating temperature of 1000 K.

• Journal of Korean Society for Atmospheric Environment
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• v.15 no.6
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• pp.713-725
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• 1999

Air pollutants($SO_2$, NOx, $O_3$ and aerosol number) were measured using an aircraft to investigate the characteristical features of long-range transport of sulfur compounds over the Yellow Sea for the periods of 26~27 April and 7~10 November in 1998. The mean $SO_2$ concentrations of April 26th~27th and November 7th~10th flight were 0.6~1.8 ppb and 0.5~8.3 ppb, respectively, and the sulfur transport was largely limited to the atmospheric boundary layer. Especially, $SO_2$ increased up to 8.3 ppb altogether with the increase of particle number concentraton especially on November 8, 1998. In addition, $O_3$ was remarkably decreased against the increase of $SO_2$and particle number concentrations. This enhanced $SO_2$ concentration occurred in the low level westerlies in association with the anticyclonic flow over Southern China and the cyclonic circulation over Manchuria. Aerosol analyses at Taean site also showed that sulfate concentration increased 2~3 times higher than those of another sampling days, which could suggest possible interactions between aerosol particels and tropospheric ozone. A rigorous evaluation will be possible after the more intensive measurements and quantitative analyses with detailed chemistry model including the postulated heterogeneous mechanism.

• Journal of Pharmaceutical Investigation
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• v.40 no.6
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• pp.321-332
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• 2010

Growing interest in the nasal route as a drug delivery system calls for a reliable in vitro model which is crucial for efficiently evaluating drug transport through the nasal cells. Various in vitro cell culture systems has thus been developed to displace the ex vivo excised nasal tissue and in vivo animal models. Due to species difference, results from animal studies are not sufficient for estimating the drug absorption kinetics in humans. However, the difficulty in obtaining reliable human tissue source limits the use of primary culture of human nasal epithelial cells. This shortage of human nasal tissue has therefore prompted studies on the "passage" culture of nasal epithelial cells. A serially passaged primary human nasal epithelial cell monolayer system developed by the air-liquid interface (ALI) culture is known to promote the differentiation of cilia and mucin gene and maintain high TEER values. Recent studies on the in vitro nasal cell culture systems for drug transport studies are reviewed in this article.

• Proceedings of the SAREK Conference
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• 2006.06a
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• pp.333-338
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• 2006

This study is a research on Dual Bore heat pipe to investigate the ability of heat transport ability, heat resistance and difference of heat transport ability according to the type of heat pipes. As the result of this research, we got several conclusions. Each pipe of Dual Bore in one section has a similar heat transfer capability. In the range between $-20^{\circ}C$ and $60^{\circ}C$ the heat transfer capability is double than single bore which was analyzed by menas of GAP program. Heat resistance is below $0.05^{\circ}C$/W at every point, and it tells aluminum-ammonia heat pipes are proper for satellite.