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Feasibility of Three-Dimensional Balanced Steady-State Free Precession Cine Magnetic Resonance Imaging Combined with an Image Denoising Technique to Evaluate Cardiac Function in Children with Repaired Tetralogy of Fallot

  • YaFeng Peng;XinYu Su;LiWei Hu;Qian Wang;RongZhen Ouyang;AiMin Sun;Chen Guo;XiaoFen Yao;Yong Zhang;LiJia Wang;YuMin Zhong
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1525-1536
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    • 2021
  • Objective: To investigate the feasibility of cine three-dimensional (3D) balanced steady-state free precession (b-SSFP) imaging combined with a non-local means (NLM) algorithm for image denoising in evaluating cardiac function in children with repaired tetralogy of Fallot (rTOF). Materials and Methods: Thirty-five patients with rTOF (mean age, 12 years; range, 7-18 years) were enrolled to undergo cardiac cine image acquisition, including two-dimensional (2D) b-SSFP, 3D b-SSFP, and 3D b-SSFP combined with NLM. End-diastolic volume (EDV), end-systolic volume (ESV), stroke volume (SV), and ejection fraction (EF) of the two ventricles were measured and indexed by body surface index. Acquisition time and image quality were recorded and compared among the three imaging sequences. Results: 3D b-SSFP with denoising vs. 2D b-SSFP had high correlation coefficients for EDV, ESV, SV, and EF of the left (0.959-0.991; p < 0.001) as well as right (0.755-0.965; p < 0.001) ventricular metrics. The image acquisition time ± standard deviation (SD) was 25.1 ± 2.4 seconds for 3D b-SSFP compared with 277.6 ± 0.7 seconds for 2D b-SSFP, indicating a significantly shorter time with the 3D than the 2D sequence (p < 0.001). Image quality score was better with 3D b-SSFP combined with denoising than with 3D b-SSFP (mean ± SD, 3.8 ± 0.6 vs. 3.5 ± 0.6; p = 0.005). Signal-to-noise ratios for blood and myocardium as well as contrast between blood and myocardium were higher for 3D b-SSFP combined with denoising than for 3D b-SSFP (p < 0.05 for all but septal myocardium). Conclusion: The 3D b-SSFP sequence can significantly reduce acquisition time compared to the 2D b-SSFP sequence for cine imaging in the evaluation of ventricular function in children with rTOF, and its quality can be further improved by combining it with an NLM denoising method.

Deep Learning Algorithm for Simultaneous Noise Reduction and Edge Sharpening in Low-Dose CT Images: A Pilot Study Using Lumbar Spine CT

  • Hyunjung Yeoh;Sung Hwan Hong;Chulkyun Ahn;Ja-Young Choi;Hee-Dong Chae;Hye Jin Yoo;Jong Hyo Kim
    • Korean Journal of Radiology
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    • v.22 no.11
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    • pp.1850-1857
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    • 2021
  • Objective: The purpose of this study was to assess whether a deep learning (DL) algorithm could enable simultaneous noise reduction and edge sharpening in low-dose lumbar spine CT. Materials and Methods: This retrospective study included 52 patients (26 male and 26 female; median age, 60.5 years) who had undergone CT-guided lumbar bone biopsy between October 2015 and April 2020. Initial 100-mAs survey images and 50-mAs intraprocedural images were reconstructed by filtered back projection. Denoising was performed using a vendor-agnostic DL model (ClariCT.AITM, ClariPI) for the 50-mAS images, and the 50-mAs, denoised 50-mAs, and 100-mAs CT images were compared. Noise, signal-to-noise ratio (SNR), and edge rise distance (ERD) for image sharpness were measured. The data were summarized as the mean ± standard deviation for these parameters. Two musculoskeletal radiologists assessed the visibility of the normal anatomical structures. Results: Noise was lower in the denoised 50-mAs images (36.38 ± 7.03 Hounsfield unit [HU]) than the 50-mAs (93.33 ± 25.36 HU) and 100-mAs (63.33 ± 16.09 HU) images (p < 0.001). The SNRs for the images in descending order were as follows: denoised 50-mAs (1.46 ± 0.54), 100-mAs (0.99 ± 0.34), and 50-mAs (0.58 ± 0.18) images (p < 0.001). The denoised 50-mAs images had better edge sharpness than the 100-mAs images at the vertebral body (ERD; 0.94 ± 0.2 mm vs. 1.05 ± 0.24 mm, p = 0.036) and the psoas (ERD; 0.42 ± 0.09 mm vs. 0.50 ± 0.12 mm, p = 0.002). The denoised 50-mAs images significantly improved the visualization of the normal anatomical structures (p < 0.001). Conclusion: DL-based reconstruction may enable simultaneous noise reduction and improvement in image quality with the preservation of edge sharpness on low-dose lumbar spine CT. Investigations on further radiation dose reduction and the clinical applicability of this technique are warranted.

A Study on the Drug Classification Using Machine Learning Techniques (머신러닝 기법을 이용한 약물 분류 방법 연구)

  • Anmol Kumar Singh;Ayush Kumar;Adya Singh;Akashika Anshum;Pradeep Kumar Mallick
    • Advanced Industrial SCIence
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    • v.3 no.2
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    • pp.8-16
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    • 2024
  • This paper shows the system of drug classification, the goal of this is to foretell the apt drug for the patients based on their demographic and physiological traits. The dataset consists of various attributes like Age, Sex, BP (Blood Pressure), Cholesterol Level, and Na_to_K (Sodium to Potassium ratio), with the objective to determine the kind of drug being given. The models used in this paper are K-Nearest Neighbors (KNN), Logistic Regression and Random Forest. Further to fine-tune hyper parameters using 5-fold cross-validation, GridSearchCV was used and each model was trained and tested on the dataset. To assess the performance of each model both with and without hyper parameter tuning evaluation metrics like accuracy, confusion matrices, and classification reports were used and the accuracy of the models without GridSearchCV was 0.7, 0.875, 0.975 and with GridSearchCV was 0.75, 1.0, 0.975. According to GridSearchCV Logistic Regression is the most suitable model for drug classification among the three-model used followed by the K-Nearest Neighbors. Also, Na_to_K is an essential feature in predicting the outcome.

A Simulation Study of the Inset-fed 2-patch Microstrip Array Antenna for X-band Applications (X-band 대역용 2-패치 마이크로스트립 인셋 급전 어레이 안테나 시뮬레이션 연구)

  • Nkundwanayo Seth;Gyoo-Soo Chae
    • Advanced Industrial SCIence
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    • v.3 no.2
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    • pp.31-37
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    • 2024
  • This paper presents a single and 2-patch microstrip array antenna operated on a frequency of 10.3GHz(x-band). It outlines the process of designing a microstrip patch array antenna using CST MWS. Initially, a single microstrip antenna was designed, followed by optimization using CST MWS to attain optimal return losses and gain. Subsequently, the design was expanded to create a 2×1 microstrip inset-fed array antenna for the X-band applications. The construction material is Roger RO4350B, with specific dimensions (h=0.79mm, 𝜖r = 3.54). The achieved results include an S11 of -18dB at the resonant frequency (10.3GHz), a gain of 9.82dBi, a bandwidth of 0.165GHz, and a 3-dB beamwidth of 30°, 121° in Az(𝜑=0) and El(𝜑=90) plane, respectively. The future plan involves the fabrication of this array antenna and further expansion to a 4×4 array of microstrip antennas. It is then incorporated on the X-band applications for practical uses.

A School-tailored High School Integrated Science Q&A Chatbot with Sentence-BERT: Development and One-Year Usage Analysis (인공지능 문장 분류 모델 Sentence-BERT 기반 학교 맞춤형 고등학교 통합과학 질문-답변 챗봇 -개발 및 1년간 사용 분석-)

  • Gyeongmo Min;Junehee Yoo
    • Journal of The Korean Association For Science Education
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    • v.44 no.3
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    • pp.231-248
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    • 2024
  • This study developed a chatbot for first-year high school students, employing open-source software and the Korean Sentence-BERT model for AI-powered document classification. The chatbot utilizes the Sentence-BERT model to find the six most similar Q&A pairs to a student's query and presents them in a carousel format. The initial dataset, built from online resources, was refined and expanded based on student feedback and usability throughout over the operational period. By the end of the 2023 academic year, the chatbot integrated a total of 30,819 datasets and recorded 3,457 student interactions. Analysis revealed students' inclination to use the chatbot when prompted by teachers during classes and primarily during self-study sessions after school, with an average of 2.1 to 2.2 inquiries per session, mostly via mobile phones. Text mining identified student input terms encompassing not only science-related queries but also aspects of school life such as assessment scope. Topic modeling using BERTopic, based on Sentence-BERT, categorized 88% of student questions into 35 topics, shedding light on common student interests. A year-end survey confirmed the efficacy of the carousel format and the chatbot's role in addressing curiosities beyond integrated science learning objectives. This study underscores the importance of developing chatbots tailored for student use in public education and highlights their educational potential through long-term usage analysis.

Integrated Data Safe Zone Prototype for Efficient Processing and Utilization of Pseudonymous Information in the Transportation Sector (교통분야 가명정보의 효율적 처리 및 활용을 위한 통합데이터안심구역 프로토타입)

  • Hyoungkun Lee;Keedong Yoo
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.23 no.3
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    • pp.48-66
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    • 2024
  • According to the three amended Laws of the Data Economy and the Data Industry Act of Korea, systems for pseudonymous data integration and Data Safe Zones have been operated separately by selected agencies, eventually causing a burden of use in SMEs, startups, and general users because of complicated and ineffective procedures. An over-stringent pseudonymization policy to prevent data breaches has also compromised data quality. Such trials should be improved to ensure the convenience of use and data quality. This paper proposes a prototype system of the Integrated Data Safe Zone based on redesigned and optimized pseudonymization workflows. Conventional workflows of pseudonymization were redesigned by applying the amended guidelines and selectively revising existing guidelines for business process redesign. The proposed prototype has been shown quantitatively to outperform the conventional one: 6-fold increase in time efficiency, 1.28-fold in cost reduction, and 1.3-fold improvement in data quality.

Real-World Application of Artificial Intelligence for Detecting Pathologic Gastric Atypia and Neoplastic Lesions

  • Young Hoon Chang;Cheol Min Shin;Hae Dong Lee;Jinbae Park;Jiwoon Jeon;Soo-Jeong Cho;Seung Joo Kang;Jae-Yong Chung;Yu Kyung Jun;Yonghoon Choi;Hyuk Yoon;Young Soo Park;Nayoung Kim;Dong Ho Lee
    • Journal of Gastric Cancer
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    • v.24 no.3
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    • pp.327-340
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    • 2024
  • Purpose: Results of initial endoscopic biopsy of gastric lesions often differ from those of the final pathological diagnosis. We evaluated whether an artificial intelligence-based gastric lesion detection and diagnostic system, ENdoscopy as AI-powered Device Computer Aided Diagnosis for Gastroscopy (ENAD CAD-G), could reduce this discrepancy. Materials and Methods: We retrospectively collected 24,948 endoscopic images of early gastric cancers (EGCs), dysplasia, and benign lesions from 9,892 patients who underwent esophagogastroduodenoscopy between 2011 and 2021. The diagnostic performance of ENAD CAD-G was evaluated using the following real-world datasets: patients referred from community clinics with initial biopsy results of atypia (n=154), participants who underwent endoscopic resection for neoplasms (Internal video set, n=140), and participants who underwent endoscopy for screening or suspicion of gastric neoplasm referred from community clinics (External video set, n=296). Results: ENAD CAD-G classified the referred gastric lesions of atypia into EGC (accuracy, 82.47%; 95% confidence interval [CI], 76.46%-88.47%), dysplasia (88.31%; 83.24%-93.39%), and benign lesions (83.12%; 77.20%-89.03%). In the Internal video set, ENAD CAD-G identified dysplasia and EGC with diagnostic accuracies of 88.57% (95% CI, 83.30%-93.84%) and 91.43% (86.79%-96.07%), respectively, compared with an accuracy of 60.71% (52.62%-68.80%) for the initial biopsy results (P<0.001). In the External video set, ENAD CAD-G classified EGC, dysplasia, and benign lesions with diagnostic accuracies of 87.50% (83.73%-91.27%), 90.54% (87.21%-93.87%), and 88.85% (85.27%-92.44%), respectively. Conclusions: ENAD CAD-G is superior to initial biopsy for the detection and diagnosis of gastric lesions that require endoscopic resection. ENAD CAD-G can assist community endoscopists in identifying gastric lesions that require endoscopic resection.

A Study on Serum Lipid Levels in Elderly People in Wando Area - Based on Age, BMI, WHR - (완도지역 성인 및 노인의 혈청지질 수준에 관한 연구(I) - 연령, 신체 계측치를 중심으로 -)

  • Cha, Bok-Kyeong
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.35 no.1
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    • pp.68-77
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    • 2006
  • This study was peformed to document the association between nutrient intakes, body mass index (BMI), waist/hip ratio (WHR), and a major risk factor for chronic diseases. A three-day dietary intake survey, using a 24 hour recall method, was obtained from 187 subjects aged 46 to 84 (mean age 65.3) living in Wando island area. The average daily mean energy intakes were 1869.0 kcal for male and 1943.9 kcal for female, respectively. Daily intakes of protein for male and female were 28.0 and 30.4 g, and those of fat were 31.5 and 28.51 g, respectively Carbohydrate dependency was decreased with age. Protein dependency was increased with age. The mean intakes of energy, protein, Vit. A, Vit. D, Vit. E, Ca, Zn did not meet Korean RDA for elderly. The level of serum triglyceride was higher in males than in females and showed the tendency to increase with age in both sexes, whereas HDL-cholesterol tended to decrease with age in both sexes. The levels of serum total-cholesterol and LDL-cholesterol were significantly higher in males than in females, particularly in the age of $46\~59$ (p<0.05). The level of atherogenic index (AI) was significantly higher in females than in males, particularly in the age of 80 and over (p<0.05) Based on these results, it is evident that people in island area did not consume enough nutrient. Specially, dietary intake of protein was not adequate. This study implies that triglyceride, total-cholesterol, LDL-cholesterol, AI were increased with increasing age, BMI and WHR.

Effect of Bulnesia sarmienti Single and Complex Extracts on Serum Lipid and Body Fat in Rats Fed High-fat Diet (고지방식이를 섭취한 흰쥐에서 Bulnesia sarmienti 단일추출물과 복합추출물이 혈청지질 및 체지방에 미치는 영향)

  • Park, Chang-Ho;Kim, Dae-Ik;Jung, Hee-Kyoung;Lee, Gee-Dong;Kim, Kil-Soo;Hong, Joo-Heon
    • Korean Journal of Food Science and Technology
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    • v.40 no.4
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    • pp.449-454
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    • 2008
  • This research examined whether feeding single extracts or complex extracts of Bulnesia sarmienti, together with a high fat diet, could improve serum lipid levels and reduce fat mass in rats. Test groups were fed the extracts, combined with a high fat diet, for eight weeks, and subdivided into seven groups: normal, control, and five treatment groups (BS: B. sarmienti extracts; BS-S: B. sarmienti and Salvia miltiorrhiza Bunge extracts; BS-M: B. sarmienti and Morus alba Linne extracts; BS-SM1: B. sarmienti, Salvia miltiorrhiza Bunge and Morus alba Linne extracts; and BS-SM2: BS-SM1 extracts at a 2-fold concentration). After feeding the test substance for 8 weeks, no significant differences were found for food intake, water intake, change in body weight, or food efficiency ratios (FER) among the groups. However, serum LDL-cholesterol had increased by 14.1% in the BS-S group. When compared with the control group, total cholesterol levels in the BS, BS-S, BS-M, BS-SM1, and BS-SM2 groups were reduced by 36.0, 14.5, 40.4, 17.5, and 22.5%, respectively, with the greatest change shown in the BS-M group. In terms of triglycerides, levels in BS, BS-S, BS-M, BS-SM1, and BS-SM2 had decreased by 41.9, 8.5, 62.3, 17.7, and 14.5%, respectively. Compared to the control group, the BS group showed a significant decrease in fat mass. In conclusion, the BS and BS-M groups showed significant effects with respect to improved serum lipid profiles and body fat mass when they were fed a high fat diet in combination with the respective extracts.

Removal of Pesticides during Washing and Cooking of Rice (쌀의 세척 및 취반에 따른 잔류농약의 제거)

  • Hwang, Lae-Hwong;Kim, Ae-Kyung;Jung, Bo-Kyung;Lee, Jae-Kyoo;Shin, Jae-Min;Park, Young-Hye;Park, Hye-Won;Kim, Min-Jeong;Park, Kyung-Ai;Yun, Eun-Sun;Kim, Moo-Sang
    • Journal of Food Hygiene and Safety
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    • v.28 no.1
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    • pp.31-35
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    • 2013
  • In this study, the pesticide residues of polished rice and brown rice were measured after washing and cooking process. The initial concentrations of isoprothiolane and fthalide were $7.134{\pm}0.03mg/kg$ and $2.024{\pm}0.04mg/kg$ for polished rice, and $17.941{\pm}1.41mg/kg$ and $6.413{\pm}0.19mg/kg$ for brown rice, respectively. After first washing process, the removal rates of isoprothiolane were 23.0% (polished rice) and 18.5% (brown rice). Also, the case of fthalide, the removal rates were 14.0% and 9.7%, respectively. The removal dose was increased, but the removal rate was decreased in proportion to the number of washing process, After the cooking process, the removal rates of isoprothiolane and fthalide were 66.0% and 79.0% (polished rice), and 88.7% and 92.9% (brown rice), respectively. The removal rate of isoprothiolane was higher in the washing process, and the case of fthalide was higher in the cooking process. The optimum washing process for the pesticides removal was five times and the cooking process was the most effective to use the new water after soaking the rice in water during 30 minutes.