• Asian-Australasian Journal of Animal Sciences
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• v.33 no.11
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• pp.1770-1778
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• 2020

Objective: This study was conducted to reveal potential metabolic differences of dairy cows fed corn stover (CS) and rice straw (RS) instead of alfalfa hay (AH) as main forage source. Methods: Thirty multiparous mid-late lactation Holstein dairy cows were selected and randomly assigned to three diets, AH, CS, or RS (n = 10). After 13 weeks of the feeding trial, coccygeal arterial and superficial epigastric venous plasma samples were collected before morning feeding for gas chromatography time-of-flight/mass spectrometry analyses. Results: In the artery, 8 and 13 metabolites were detected as differential metabolites between AH and CS, and between AH and RS, respectively. The relative abundance of phenylpropanoate (log₂fold change [FC]) = 1.30, 1.09), panthenol (log₂FC = 2.36, 2.20), threitol (log₂FC = 1.00, 1.07), and 3,7,12-trihydroxycoprostane (log₂FC = 0.79, 0.78) were greater in both CS and RS than in AH, and tyrosine (log₂FC = -0.32), phenylalanine (log₂FC = -0.30), and pyruvic acid (log₂FC = -0.30) were lower in RS than in AH. In the vein, 1 and 7 metabolites were detected as differential metabolites between AH and CS, and between AH and RS, respectively. By comparing AH and RS, we found that metabolic pathways of phenylalanine, tyrosine, and tryptophan biosynthesis and phenylalanine metabolism were enriched by integrative artery and vein analysis. Furthermore, AH and RS, arterial phenylpropanoate and 4-hydroxyproline were positively, and phenylalanine was negatively correlated with milk urea nitrogen. Finally, in AH and CS, arterial panthenol was negatively correlated with feed efficiency. Conclusion: Arterial metabolic profiles changed more than those in the veins from animals on three forage diets, differing in amino acids. We found that phenylalanine, tyrosine, and tryptophan biosynthesis and phenylalanine metabolism were restricted when cows were fed low-quality cereal straw diets.

• Restorative Dentistry and Endodontics
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• v.39 no.1
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• pp.17-23
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• 2014

Objectives: This study evaluated the efficacy of Endosolv-R and Xylene in softening epoxy resin based sealer after 1 to 2 min exposure. Materials and Methods: Sixty Teflon molds ($6mm{\times}1.5mm$ in inner diameter and depth) were equally divided into 3 groups of 20 each. AH 26 (Dentsply/De Trey), AH Plus (Dentsply/De Trey), Adseal (Meta-Biomed) were manipulated and placed in the molds allotted to each group and allowed to set at $37^{\circ}C$ in 100% humidity for 2 wk. Each group was further divided into 2 subgroups according to the solvents used, i.e. Xylene (Lobachemie) and Endosolv-R (Septodont). Specimens in each subgroup were exposed to respective solvents for 1 and 2 min and the corresponding Vicker's microhardness (HV) was assessed. Data was analysed by Mauchly's test and two-way analysis of variance (ANOVA) with repeated measures, and one-way ANOVA. Results: Initial hardness was significantly different among the three sealers with AH Plus having the greatest and Adseal having the least. After 2 min, Xylene softened AH Plus and Adseal sealer to 11% and 25% of their initial microhardness, respectively (p < 0.001), whereas AH 26 was least affected, maintaining 89.4% of its initial microhardness. After 2 min, Endosolv-R softened AH 26, AH Plus and Adseal to 12.7, 5.6 and 8.1% of their initial microhardness, respectively (p < 0.001). Conclusions: Endosolv-R was a significantly more effective short term softener for all the tested sealers after 2 min whereas Xylene was an effective short term softener against AH plus and Adseal but less effective against AH 26.

• Journal of Digital Convergence
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• v.17 no.1
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• pp.443-447
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• 2019

Aryl hydrocarbon receptor (AhR) is the master regulator of xenobiotics metabolizing enzymes (XMEs). AhR is activated by aryl hydrocarbons upon binding then goes into the cell nucleus and acts as a transcription factor. Despite the role of AhR in human physiology has been investigated for a long while, it is yet to be understood mainly due to the lack of appropriate chemical agents. Furthermore, it has been reported that AhR is related to a wide range of pathogenesis. In addition, recent studies suggest that the study on the development of AhR antagonist may provide a valid therapeutic agent. Some known antagonists in current use are partially agonistic whereas a pure antagonist is still absent. In this study, two phenyl-ring structures of phenyldiazenylphenylpicolinamide has been modified into various structures and evaluated its impact on the AhR antagonistic activity to elucidate the structure-activity relationship.

• Journal of the Korean Society for Railway
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• v.12 no.6
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• pp.873-877
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• 2009

In order to use railway system standby power, produced 160Ah NiMH battery that would be able to substitute the lead acid battery or NiCd battery form which contain the toxic material in environment, using parallel connected 80Ah NiMH battery. And in order to develop proper electrode in the 160Ah NiMH battery, tested high rate discharge performance of the ternary electrolyte. 160Ah NiMH battery evaluated the various test in order to use railway system standby power.

• Proceedings of the KSR Conference
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• 2006.11b
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• pp.636-645
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• 2006

In order to use railway system standby power, produced 160Ah NiMH battery that would be able to substitute the lead acid battery or NiCd battery form which contain the toxic material in environment, using parallel connected 80Ah NiMH battery. And in order to develop proper electrode in the 160Ah NiMH battery, tested high rate discharge performance of the ternary electrolyte. 160Ah NiMH battery evaluated the various test in order to use railway system standby power.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.11a
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• pp.228-231
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• 2022

'코로나19'의 여파로 인해 많은 분야에서 비대면 회의 및 상거래가 활성화되면서 기존 홈쇼핑에서의 방송 시스템 방식이 아닌 간단하게 구성할 수 있는 라이브 커머스의 중요성이 대두되었다. 시스템적으로 간편함을 갖춘 동시에 누구나 쉽게 접근을 할 수 있는 시스템을 구성하여 제안하고자 한다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2022.11a
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• pp.222-224
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• 2022

지난 2021년, 국내 최초로 온라인 소비가 오프라인 소비를 뛰어넘을 정도로 언택트 경제가 급부상하였다. 덕분에 언택트 시장의 주도권을 가진 라이브 커머스는 무서운 속도로 성장하고 있고, 이는 적어도 2023년까지 이어질 것으로 예상된다. 중소기업은 물론 대기업, 심지어 개인까지 라이브 커머스 시장에 탑승한 현재, 라이브 커머스 시장의 경쟁력은 점차 사라지고 있다. 이로 인해 공급자들은 차별성을 두기 위해 여전히 다양한 방법을 찾아 시도하고 있다. 본 논문에서는 계속해서 수요되는 라이브 커머스 시장에서 경쟁력을 갖출 수 있는 방법으로 LED Wall의 활용을 제안한다.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• fall
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• pp.238-241
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• 2021

코로나가 지속됨에 따라 많은 사람들이 언택트 생활 방식에 적응하고 있다. 기존 홈쇼핑과는 달리 실시간으로 상호 소통이 가능한 라이브 커머스가 등장하면서 쇼핑문화는 점차 발전하는 추세이다. 본 논문에서는 성장하는 라이브 커머스 시장에 맞춰 간편함을 갖춘 동시에 더 나은 품질의 방송을 제공하고자 4차 산업혁명의 산물인 '드론'을 접목하며 새로운 차원의 라이브 커머스 시스템을 구현하고자 한다.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.44 no.4
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• pp.447-453
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• 2018

Acetyl hexapeptide 8 (AH8) is a synthetic peptide for anti-wrinkle cosmetics ingredient. It was developed as a mimetic of botox, patternd after N -terminal end of the protein synatosomal-associated protein 25 (SNAP25), a substrate of botulinum toxin. While AH8 has good efficacy and safety profiles, the permeation through the skin is poor. Therefore, we tried to enhance the transdermal delivery of AH8 by using of hyaluonic acid (HA), a linear polysaccharide of N-acetyl glucosamine and glucuronic acid. To investigate the effect of HA on AH8 penetration, we analyzed paraffin sections of $Micropig^{(R)}$ skin. Fluorescence labeled AH8 was applied to micropig skin with or without HA. The absorption of AH8 was limited to the stratum corneum (SC) without HA. On the other hand, AH8 penetrated to the dermis with HA. Especially, low molecular weight HA (5 kDa) was most efficient compared to 500 kDa HA and 2000 kDa HA. Experiments using fourier-transform infrared (FTIR) spectroscopy revealed that lower molecular weight HA had a tendency to increase the fluidity of the SC lipids more, which means enhancing the skin penetration. Therefore, HA could be expected to enhance the anti-wrinkle effect of AH8.

• Journal of Intelligence and Information Systems
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• v.13 no.3
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• pp.63-82
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• 2007

In this paper, we propose an adaptive hybrid genetic algorithm (ahGA) approach for effectively solving multistage-based scheduling problems in flexible manufacturing system (FMS) environment. The proposed ahGA uses a neighborhood search technique for local search and an adaptive scheme for regulation of GA parameters in order to improve the solution of FMS scheduling problem and to enhance the performance of genetic search process, respectively. In numerical experiment, we present two types of multistage-based scheduling problems to compare the performances of the proposed ahGA with conventional competing algorithms. Experimental results show that the proposed ahGA outperforms the conventional algorithms.