• 제목/요약/키워드: Aging state

검색결과 505건 처리시간 0.026초

조선왕조실록 밀랍본 복원기술연구(제1보) - 재현밀랍지의 열화거동평가 - (The Study of Restoration Technique of Wax-treated Volume for the Annals of the Joseon Dynasty(I) - Evaluation of degradation behavior of reproduced waxy paper -)

  • 정선화;정소영;서진호;이혜윤
    • 펄프종이기술
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    • 제39권1호
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    • pp.56-63
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    • 2007
  • The purpose of this research was to identify causes of damage of wax-treated volume of "The Annals of the Joseon Dynasty". As one of the efficient restoration methods, analyses of damaged state of reproduced wax-treated paper through tests of degradation of wax-treated paper under an artificial setting were performed, and in particular, differences between lightness and acidity were observed. On the whole, it was confirmed that yellow wax-treated papers were more stable than white wax-treated papers against artificial aging treatment, which is thought to be because the white wax-treated paper was more affected by a variety of substances interacting with paper than yellow wax-treated paper under artificially aged conditions, which were added in the course of refinement and processing operation such as decolorization and deodorization.

Design of Smart Farm with Automatic Transportation Function

  • Hur, Hwa-ra;Park, Seok-Gyu;Park, Myeong-Chul
    • 한국컴퓨터정보학회논문지
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    • 제24권8호
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    • pp.37-43
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    • 2019
  • The existing smart farm technology has been systematized for the mass production rather than the consumer. There are many problems such as economical aspect to apply to actual rural environment due to aging. The purpose of this study is to apply smart farm technology based on the applicability of population aged in rural areas. Due to the heat wave, the crops in general greenhouse cultivation facilities suffered from damage such as sunlight damage. To minimize such damage, adjust the temperature and humidity environment or install a light-shielding film. However, the workers in the rural areas are aging and the elderly who are farming alone have a lot of difficulties in doing so. In the case of people with weak physical strength, there is a danger that they may lead to safety accidents when carrying heavy loads. In this paper, we propose 'Smart Palm capable of automatic transportation function', applying small smart vehicles that follow workers to existing smart farms to improve and prevent these problems. It is a smart farm that performs the control functions of the existing smart greenhouse environment, installs the rail for each trough, and has a vehicle that follows the worker. The smart app can directly control the greenhouse and the vehicle remotely manually.

Post-Harvest Strategies to Improve Tenderness of Underutilized Mature Beef: A Review

  • Tuell, Jacob R.;Nondorf, Mariah J.;Kim, Yuan H. Brad
    • 한국축산식품학회지
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    • 제42권5호
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    • pp.723-743
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    • 2022
  • Beef muscles from mature cows and bulls, especially those originating from the extremities of the carcass, are considered as underutilized due to unsatisfactory palatability. However, beef from culled animals comprises a substantial proportion of the total slaughter in the US and globally. Modern consumers typically favor cuts suitable for fast, dry-heat cookery, thereby creating challenges for the industry to market inherently tough muscles. In general, cull cow beef would be categorized as having a lower extent of postmortem proteolysis compared to youthful carcasses, coupled with a high amount of background toughness. The extent of cross-linking and resulting insolubility of intramuscular connective tissues typically serves as the limiting factor for tenderness development of mature beef. Thus, numerous post-harvest strategies have been developed to improve the quality and palatability attributes, often aimed at overcoming deficiencies in tenderness through enhancing the degradation of myofibrillar and stromal proteins or physically disrupting the tissue structure. The aim of this review is to highlight existing and recent innovations in the field that have been demonstrated as effective to enhance the tenderness and palatability traits of mature beef during the chilling and postmortem aging processes, as well as the use of physical interventions and enhancement.

DEVELOPMENT OF POLYETHOXYLATED RETINAMIDE AS AN ANTl-AGINC AGENT

  • Song, Young-Sook;Chung, Bong-Yul;Chang, Min-Youl;Park, Mun-Eok;Lee, Sung-Jun;Cho, Wan-Goo;Kang, Seh-Hoon
    • 대한화장품학회:학술대회논문집
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    • 대한화장품학회 1999년도 IFSCC . ASCS 학술대회 발표 논문
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    • pp.145-154
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    • 1999
  • A novel retinol derivative, polyethoxylated retinamide (Medimin A) was synthesized, as an anti-aging agent. Collagen synthesis, skin permeation, stability, and toxicity of Medimin A were evaluated and compared with those of retinol and retinyl palmitate. In vitro collagen synthesis was evaluated by quantitative assay of [$^3H$]-proline incorporation into collagenase sensitive protein in fibroblast cultures. For in vitro skin permeation experiments, Franz diffusion cells (effective diffusion area: $1, 766{\;}\textrm{cm}^2$) and the excised skin of female hairless mouse aged 8 weeks were used The stabilities of retlnoids were evaluated at two different temperature ($25{\;}^{\circ}C$ and $40{\;}^{\circ}C$) and under UV in solubilized state and in OW emulsion. To estimate the safety, acute oral toxicity, acute dermal toxicity, primary skin irritation, acute eye irritation and human patch test were performed The effect of Medimin A on collagen synthesis was similar to that of retinol. The skin permeability of Medimin A was higher than those of retinol and retinyl palmitate. The Medimin A was more stable than retinol and retinyl palmitate. Medimin A was nontoxic in various toxicological tests. These results suggest that Medimin A would be a good anti-aging agent for enhancing bioavailability and stability.

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The information system concept for thermal monitoring of a spent nuclear fuel storage container

  • Svitlana Alyokhina
    • Nuclear Engineering and Technology
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    • 제55권10호
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    • pp.3898-3906
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    • 2023
  • The paper notes that the most common way of handling spent nuclear fuel (SNF) of power reactors is its temporary long-term dry storage. At the same time, the operation of the dry spent fuel storage facilities almost never use the modern capabilities of information systems in safety control and collecting information for the next studies under implementation of aging management programs. The author proposes a structure of an information system that can be implemented in a dry spent fuel storage facility with ventilated storage containers. To control the thermal component of spent fuel storage safety, a database structure has been developed, which contains 5 tables. An algorithm for monitoring the thermal state of spent fuel was created for the proposed information system, which is based on the comparison of measured and forecast values of the safety criterion, in which the level of heating the ventilation air temperature was chosen. Predictive values of the safety criterion are obtained on the basis of previously published studies. The proposed algorithm is an implementation of the information function of the system. The proposed information system can be used for effective thermal monitoring and collecting information for the next studies under the implementation of aging management programs for spent fuel storage equipment, permanent control of spent fuel storage safety, staff training, etc.

Quercetin-induced apoptosis ameliorates vascular smooth muscle cell senescence through AMP-activated protein kinase signaling pathway

  • Kim, Seul Gi;Sung, Jin Young;Kim, Jae-Ryong;Choi, Hyoung Chul
    • The Korean Journal of Physiology and Pharmacology
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    • 제24권1호
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    • pp.69-79
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    • 2020
  • Aging is one of the risk factors for the development of cardiovascular diseases. During the progression of cellular senescence, cells enter a state of irreversible growth arrest and display resistance to apoptosis. As a flavonoid, quercetin induces apoptosis in various cells. Accordingly, we investigated the relationship between quercetin-induced apoptosis and the inhibition of cellular senescence, and determined the mechanism of oxidative stress-induced vascular smooth muscle cell (VSMC) senescence. In cultured VSMCs, hydrogen peroxide (H2O2) dose-dependently induced senescence, which was associated with increased numbers of senescence-associated β-galactosidase-positive cells, decreased expression of SMP30, and activation of p53-p21 and p16 pathways. Along with senescence, expression of the anti-apoptotic protein Bcl-2 was observed to increase and the levels of proteins related to the apoptosis pathway were observed to decrease. Quercetin induced apoptosis through the activation of AMP-activated protein kinase. This action led to the alleviation of oxidative stress-induced VSMC senescence. Furthermore, the inhibition of AMPK activation with compound C and siRNA inhibited apoptosis and aggravated VSMC senescence by reversing p53-p21 and p16 pathways. These results suggest that senescent VSMCs are resistant to apoptosis and quercetin-induced apoptosis attenuated the oxidative stress-induced senescence through activation of AMPK. Therefore, induction of apoptosis by polyphenols such as quercetin may be worthy of attention for its anti-aging effects.

DEVELOPMENT OF POLYETHOXYLATED RETINAMIDE AS AN ANTI-AGING AGENT

  • Song, Young-Sook;Chung, Bong-Yul;Chang, Min-Youl;Park, Mun-Eok;Lee, Sung-Jun;Cho, Wan-Goo;Kang, Seh-Hoon
    • 대한화장품학회지
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    • 제25권4호
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    • pp.145-154
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    • 1999
  • A novel retinol derivative, polyethoxylated retinamide(Medimin A) was synthesized, as an anti-aging agent. Collagen synthesis, skin permeation, stability, and toxicity of Medimin A were evaluated and compared with those of retinol and retinyl palmitate. In vitro collagen synthesis was evaluated by quantitative assay of $[^3H]-proline$ incorporation into collagenase sensitive protein in fibroblast cultures. For in vitro skin permeation experiments, Franz diffusion cells(effective diffusion area: 1,766 $cm^2$) and the excised skin of female hairless mouse aged 8 weeks were used, The stabilities of retinoids were evaluated at two different temperature($25^{\circ}C\;and\;40^{\circ}C$) and under UV in solubilized state and in O/W emulsion. To estimate the safety, acute oral toxicity, acute dermal toxicity, primary skin irritation, acute eye irritation and human patch test were performed. The effect of Medimin A on collagen synthesis was similar to that of retinol. The skin permeability of Medimin A was higher than those of retinol and retinyl palmitate. The Medimin A was more stable than retinol and retinyl palmitate. Medimin A was nontoxic in various toxicological tests. These results suggest that Medimin A would be a good anti-aging agent for enhancing bioavailability and stability.

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베이비부머의 은퇴주택 계획을 위한 주거생활상과 주거생활지원서비스 조사연구 - 재미 한인 베이비부머를 중심으로 - (Baby Boomers' Residential Life Images and Supportive Service Needs at Post-retirement Homes - With a Focus on Korean-American Immigrants -)

  • 김미희;김석경
    • 한국실내디자인학회논문집
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    • 제22권5호
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    • pp.3-10
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    • 2013
  • The principle of aging-in-place should be fundamental in designing post-retirement homes to support baby boomers' healthy aging in their current living conditions. This study investigated Korean-American baby boomers' opinions about their life images in their post-retirement homes and the needs for supportive services therein. A questionnaire survey was conducted, and a total of 247 responses were used for statistical analyses. As the most important life image for their post-retirement homes, baby boomers emphasized the living environments offering various recreational activities. They indicated the post-retirement homes close to their children or family members as the next important life image. These opinions differed depending on their socioeconomic characteristics. In particular, baby boomers with higher-income preferred housing environments offering diverse recreational activities while those with lower-income preferred the housing close to more employment opportunities. In terms of supportive services available in the post-retirement homes, they wanted 'healthcare assistance services' and 'diverse recreational programs.' Gender, educational attainment, and annual income affected their preferences in these services, though. Based on the findings, this study concluded that post-retirement housing environments should create spaces to accommodate various recreational activities and include places for them to work in near-home environments. In the community, various need-based customized recreational activities and educational programs should be planned considering different socioeconomic characteristics of baby boomers. All these considerations will provide supportive residential environments for their successful aging in place.

노후 건강 및 복지증진을 위한 평생교육 프로그램개발에 관한 연구: 대학 내 노년학센터(가칭)의 설치운영을 중심으로 (A Study on the Development of Lifelong Educational Programs for the Promotion of Health and Welfare in Later Life: Centering around the Establishment and Management of Aging Center in University)

  • 김형수;이원재
    • 보건교육건강증진학회지
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    • 제20권1호
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    • pp.203-218
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    • 2003
  • In aging Korean society, many elderly people have difficulty in the areas of health, economic insecurity, role-loss(both work & spouse), loneliness, and family conflicts. Above all, retirement from work is one of the most important stressful life events having influences an elderly's persons economic & social activities, mental state, health status, and Lifelong educational programs could help the aged cope with these situations in later life. Health and social welfare are commonly recognized as an important value of life. They also have an effect on each other. Most people agree that the promotion of health and social welfare is to take a short-cut toward achieving well-being. Thus we need to develop a substantially integrated program of lifelong education, before and after retirement, for the promotion of health and welfare. Universities have the advantage of practicing lifelong educational programs because they have more material, intellectual, and human resources than any other educational facilities. As a result, the purposed of this study is to suggest life-long educational programs for promoting both health conditions and the level of social welfare by utilizing an aging center affiliated with a university. Specifically, the developmental courses of pre-retirement, learning in retirement, elder-hostels, and the connection between pre and post-retirement educational programs are proposed in this study.

An improved regularized particle filter for remaining useful life prediction in nuclear plant electric gate valves

  • Xu, Ren-yi;Wang, Hang;Peng, Min-jun;Liu, Yong-kuo
    • Nuclear Engineering and Technology
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    • 제54권6호
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    • pp.2107-2119
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    • 2022
  • Accurate remaining useful life (RUL) prediction for critical components of nuclear power equipment is an important way to realize aging management of nuclear power equipment. The electric gate valve is one of the most safety-critical and widely distributed mechanical equipment in nuclear power installations. However, the electric gate valve's extended service in nuclear installations causes aging and degradation induced by crack propagation and leakages. Hence, it is necessary to develop a robust RUL prediction method to evaluate its operating state. Although the particle filter(PF) algorithm and its variants can deal with this nonlinear problem effectively, they suffer from severe particle degeneracy and depletion, which leads to its sub-optimal performance. In this study, we combined the whale algorithm with regularized particle filtering(RPF) to rationalize the particle distribution before resampling, so as to solve the problem of particle degradation, and for valve RUL prediction. The valve's crack propagation is studied using the RPF approach, which takes the Paris Law as a condition function. The crack growth is observed and updated using the root-mean-square (RMS) signal collected from the acoustic emission sensor. At the same time, the proposed method is compared with other optimization algorithms, such as particle swarm optimization algorithm, and verified by the realistic valve aging experimental data. The conclusion shows that the proposed method can effectively predict and analyze the typical valve degradation patterns.