• 대한용접접합학회:학술대회논문집
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• 대한용접접합학회 2002년도 Proceedings of the International Welding/Joining Conference-Korea
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• pp.59-64
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• 2002

Effects of the aging treatments on the microstructure and strength of heat affected zone(HAZ) in the welds of a age-hardened Al-Mg-Si alloy, 5N01-T5, were investigated. The base metal aging treatments before MIG welding were conducted at 423K to 473K for 28.8ks Post weld heat treatment(PWHT) to recover the HAZ strength was performed at 448K for 28.8ks. Microstructure observations, hardness measurements and tensile tests were conducted to study properties of the MIG weld joints. The position of the softest region in HAZ where the hardness insufficiently recovered after natural aging and PWHT was at a distance of approximately 15mm from the center of the fusion zone. Hardness of the softest regions after natural aging and PWHT decreased with increase in the base metal aging temperature. TEM observation clarified that strengthening ${\beta}$"(Mg$_2$Si) precipitates and coarse ${\beta}$′ precipitates affected the hardnes of HAZ. Incomplete recover of hardness in HAZ after PWHT was caused by the precipitating of non-hardening ${\beta}$′ phase during the weld thermal cycle. In order to examine the effects of weldheat input and welding speed, the laser weld joints were also investigated and compared with the MIG weld ones. Laser welding had the narrower width of the softened regions in HAZ compared with MIG welding. The hardness of the softest regions of the laser welds after PWHT was higher than that of the MIG welds. Quantitative relations between hardness of the softest region and base metal aging temperature were obtained for both welding processes. Accordingly, the equations to estimate the strength of the weld joints after PWHT with varying base metal temperatures were proposed for MIG welding and laser welding.

• Nutrition Research and Practice
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• 제16권1호
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• pp.1-13
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• 2022

BACKGROUND/OBJECTIVES: Bitter taste receptors are taste signaling pathway mediators, and are also expressed and function in extra-gustatory organs. Skin aging affects the quality of life and may lead to medical issues. The purpose of this study was to better understand the anti-skin aging effects of bitter taste receptors in D-galactose (D-gal)-induced aged human keratinocytes, HaCaT cells. MATERIALS/METHODS: Expressions of bitter taste receptors in HaCaT cells and mouse skin tissues were examined by polymerase chain reaction assay. Bitter taste receptor was overexpressed in HaCaT cells, and D-gal was treated to induce aging. We examined the effects of bitter taste receptors on aging by using β-galactosidase assay, wound healing assay, and Western blot assay. RESULTS: TAS2R16 and TAS2R10 were expressed in HaCaT cells and were upregulated by D-gal treatment. TAS2R16 exerted protective effects against skin aging by regulating p53 and p21, antioxidant enzymes, the SIRT1/mechanistic target of rapamycin pathway, cell migration, and epithelial-mesenchymal transition markers. TAS2R10 was further examined to confirm a role of TAS2R16 in cellular senescence and wound healing in D-gal-induced aged HaCaT cells. CONCLUSIONS: Our results suggest a novel potential preventive role of these receptors on skin aging by regulating cellular senescence and wound healing in human keratinocyte, HaCaT.

• 한국엔터테인먼트산업학회논문지
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• 제14권8호
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• pp.277-285
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• 2020

본 연구의 목적은 치매에 대한 인식과 태도가 노화불안에 미치는 영향을 파악하여 노화불안을 줄이고 효과적인 치매예방 및 관리방안 마련을 위한 기초자료를 제공하고자 한다. 연구대상은 충북 J시에 거주하는 시민 509명을 대상으로 하였으며 치매 인식과 태도가 노화불안에 미치는 영향을 살펴보기 위해 다중회귀분석을 실시하였다. 본 연구결과 노화불안에 영향을 미치는 요인은 치매 인식이 유의미한 영향을 미치는 것으로 나타났다. 이는 치매 인식이 낮을수록 노화불안이 높아진다는 것을 의미한다. 그러나 치매 태도는 노화불안에 유의미한 영향을 미치지 않는 것으로 나타났다. 이러한 연구결과를 근거로 정책제언을 하면 첫째, 치매 인식 증진을 위한 체계적인 교육과 교육 프로그램의 개발이 필요하다. 둘째, 치매 인식개선을 위한 홍보 강화가 필요하다. 셋째, 치매 인식 향상을 위한 지역사회 네트워크 구축이 필요하다.

• 운동영양학회지
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• 제24권3호
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• pp.32-38
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• 2020

[Purpose] Sarcopenia is considered one of the major causes of disability in the elderly population and is highly associated with aging. Exercise is an essential strategy for improving muscle health while aging and involves multiple metabolic and transcriptional adaptations. Although the beneficial effects of exercise modalities on skeletal muscle structure and function in aging are well recognized, the exact cellular and molecular mechanisms underlying the influence of exercise have not been fully elucidated. [Methods] We summarize the biochemical pathways involved in the progression and pathogenesis of sarcopenia and describe the beneficial effects of exercise training on the relevant signaling pathways associated with sarcopenia. [Results] This study briefly introduces current knowledge on the signaling pathways involved in the development of sarcopenia, effects of aerobic exercise on mitochondria-related parameters and mitochondrial function, and role of resistance exercise in the regulation of muscle protein synthesis against sarcopenia. [Conclusion] This review suggested that the beneficial effects of exercise are still under-explored, and accelerated research will help develop better modalities for the prevention, management, and treatment of sarcopenia.

• 성인간호학회지
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• 제27권5호
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• pp.594-603
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• 2015

Purpose: The purpose of this study was to examine the effects of health promotion program on healthy aging preparation for late middle aged women. Methods: The research design was a non-equivalent control group quasi-experimental study. Participants were recruited from K and Y cities in Gyeong-nam Province from October, 2013 to January, 2014. They were 26 for the experimental group and 31 for the control group. The experimental group participated in a health promotion program for healthy aging preparation. The program consisted of education, exercise, and small group discussion over 8 weeks. Data were analyzed by Chi-square, t-test and ANCOVA, using the PASW 18.0 program. Results: There were significant improvements in aging anxiety and general self-efficacy, health promoting behaviors in the experimental group compared to those of the control group. However, there was no significant differences in attitude toward older adults between the two groups. Conclusion: The health promotion program on healthy aging preparation for late middle aged women was found to be effective in enhancing aging anxiety and self-efficacy, and health promoting behavior. Thus, the developed program is recommended for use in clinical practice as an effective nursing intervention for late middle aged women in order to keep up with their health in later life.

• 한국압력기기공학회 논문집
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• 제7권4호
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• pp.57-62
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• 2011

As NPPs' operating times increase, the integrity of nuclear components is continually degraded due to aging effects of systems, structures and components. In addition, for the case of continued operation beyond design life, additional aging effects occurred during the extended operating period lead to more degradation of the integrity of nuclear components. Therefore, it is very important to mange and evaluate the aging to secure the safety of NPPs. Wolsong unit 1 is approaching to its design life of 30 years in 2012. The license renewal documents for continued operation of Wolsong unit 1 Is under reviewing now. In this paper, regulatory technologies for continued operation of Wolsong unit 1 developed by KINS will be introduced. That technologies include the safety review guidelines, regulatory guides for aging management program and regulatory program for audit calculation.

• 한국축산식품학회지
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• 제40권5호
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• pp.844-851
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• 2020

The objective of this study was to compare effects of two different aging methods on physical, chemical, and microbial traits of pork loin: Dry and wet-aged meat was hung in the cooler at 8±1℃ and 85±2.1% humidity for 14 days, while wet-aged meat was immersed in a 3.5% salt solution of brine in vacuum pouches. On day 7, pH and moisture content were higher in dry-aged loins than in wet-aged, while drip loss and total plate counts (p<0.05) were lower on day 14. As aging continued, the pH and drip loss of dry-aged loins decreased, while their total plate counts and water holding capacity (WHC) increased (p<0.05). After 7 and 14 days of aging, redness in dry-aged loins was higher than that in wet -aged muscles (p<0.05). On day 14 of aging, hardness, chewiness, and adhesiveness were lower in dry-aged pork loin as compared to those in wet-aged samples (p<0.05). Consequently, the results suggested that dry and wet aging methods differently affects meat quality traits of pork loin.

• 한국식품영양과학회지
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• 제20권2호
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• pp.187-196
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• 1991

Aging is the progressive accumulation of changes with time associated with responsible for the ever-increasing susceptibility to disease and death which accompanies advancing age. Lipid peroxides easily produced in the membrane system by the chain reaction of free radicals which occurred from various environmental factors. The amount of lipid peroxides produced in biological system increased with aging process, and lipid peroxidation damages involved in aging process and pathological disorders. Although lipid peroxides have such deleterious effects on the organisms, there are numerous substances and mechanisms which prevent the reaction of peroxide formation and protect the subject from its toxicity. This review provides an overview of how does lipid peroxidation of unsaturated lipids take place by free radical, and what is the intervention of lipid peroxides in pathogenesis of some human diseases, and also how does food restriction influences the aging process and various pathological disorders. The major focus of this paper is to review the evidence indicating that food restriction retards the aging process, and possible mechanisms of its actions. Therefore, it discussed the effects of age and food restriction on life-span, membrane yield, lipid peroxidation, fatty acid composition and peroxidizability, cholesterol and triglyceride levels, prostaglasndin and thromboxane synthesis, which may be concerned with blood flow, membrane fluidity, homeostasis and glomerular filtration rate in living body.

• Geomechanics and Engineering
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• 제28권1호
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• pp.1-10
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• 2022

In Korea, accidents related to the collapse of deteriorated aging reservoirs occur every year. The grouting method is generally applied to reinforce an aging reservoir. However, when using this method, different reinforcing effects appear depending on the ground conditions. Thus, new construction methods and materials capable of providing consistent reinforcing effects are required. In this study, the direct shear test (DST), model test, and simulation analysis were performed to evaluate the impact of surface stabilizers, generally used to reinforce roads, rivers, and slopes of roads, applied using surface curtain walls on aging reservoirs. The DST results indicate that when the surface stabilizer was mixed with in-situ soil, the increase in cohesion was the highest at a mixing ratio of 9%. No changes in the friction angle were evident; therefore, 9% was determined to be the optimal mixing ratio. In addition, the model test and simulation analysis showed that when 9% of the surface stabilizer was mixed and applied to the aging reservoir, the seepage quantity of water and the saturated area were reduced by approximately 42% and 73%, respectively. Moreover, the comprehensive analysis of results showed that the grouting method could be completely replaced by surface stabilizers applied through surface curtain walls because the technique could secure stability by decreasing the seepage in the aging reservoir.

• International Journal of Advanced Culture Technology
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• 제6권3호
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• pp.59-68
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• 2018

This study was a cross-sectional descriptive study of the effects of emotional happiness on aging preparation for 45-60 year olds. Participants of this study were 312 volunteers and data was collected online, the collection period was from May 15, 2018 to May 31, 2018. The tools used in the research were the emotional happiness developed by Watson et al (1988) et al., the aging preparation developed by JH Lee (2009). Analysis was done using t-test, ANOVA, Pearson correlation, and regression by SPSS 18.0. As a result of the analysis, 84.0% of participants felt physically healthy and 89.8% felt mental health. The spouses of participants were physically 83.4% healthy and mentally 82.7% healthy. The correlation between emotional happiness, health cognition and aging preparation showed that physical health had a correlation with mental health (r = .482, p <0.01) and emotional happiness (r = .369, p <0.01), economic aging preparation (r = .411, p <0.01), social aging preparation (r = .119, p <0.01). Mental health was correlated with emotional happiness (r = .491, p <0.01), economic aging preparation (r = .411, p <0.01) and social aging preparation. Difference between emotional happiness and retirement preparation according to presence or absence of disease, emotional happiness (t = -4.503, p <0.01) and economic aging preparation (t = -4.960, p <0.01) were statistically significant. Emotional happiness affects the preparation of old age, emotional happiness affects to physical aging preparation under statistical significance (F=25.191, p<0.01), economic aging preparation (F=1131.783, p<0.01), and social aging preparation (F=147.672, p<0.01) which were sub components of aging preparation. Emotional happiness showed a 7.5% effect on the preparation of physical aging, 78.4% on economic aging preparation and 32.3% on social aging preparation. Based on the above results, it can be concluded that physical health and mental health are related to emotional happiness, economic aging preparation, and social aging preparation. And also these results can be inferred that the illness causes emotional less feeling of happiness and economic difficulty. Based on the results of this study, emotional well - being influences the retirement preparation significantly at statistical significance. Therefore, if the concept of emotional happiness is introduced to the old-age preparation program, it will be more client centered program.