• Title/Summary/Keyword: Aging Resistance

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Desorption Characteristics and Bioavailability of Zn to Earthworm in Mine Tailings (광미내 Zn의 탈착 특성과 지렁이에 대한 생이용성)

  • Oh, Sang-Hwa;Shin, Won-Sik
    • Journal of Soil and Groundwater Environment
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    • v.16 no.4
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    • pp.38-52
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    • 2011
  • Sorption and sequential desorption experiments were conducted for Zn using a natural soil (NS) in background status by aging (1, 30 and 100 days). The sorption isotherm showed that Zn had high sorption capacity but low sorption affinity in NS. Sequential desorption was biphasic with appreciable amount of sorbed Zn residing in the desorption-resistant fraction after several desorption steps. The biphasic desorption behavior of Zn was characterized by a biphasic desorption model that includes a linear term to represent labile or easily-desorbing fraction and a Langmuirian-type term to represent desorption-resistant fraction. The biphasic desorption model indicated that the size of the maximum capacity of desorption-resistant fraction ($q^{irr}_{max}$) increased with aging in NS. Desorption kinetics and desorption-resistance of Zn in the soils collected from mine tailings (MA, MB and MC collected from surface, subsurface soils and mine waste, respectively) were investigated and compared to the bioavailability to earthworm (Eisenia fetida). Desorption kinetic data of Zn were fitted to several desorption kinetic models. The ratio ($q_{e,d}/q_0$) of remaining Zn at desorption equilibrium ($q_{e,d}$) to initial sorbed concentration ($q_0$) was in the range of 0.53~0.90 in the mine tailings which was higher than that in NS, except MA. The sequential desorption from the mine tailings with 0.01M Na$NO_3$ and 0.01M $CaCl_2$ showed that appreciable amounts of Zn are resistant to desorption due to aging or sequestration. The SM&T (Standard Measurements and Testing Programme of European Union) analysis showed that the sum of oxidizable (Step III) and residual (Step IV) fractions of Zn was linearly related with its desorption-resistance ($q^{irr}_{max}$) determined by the sequential desorption with 0.01M Na$NO_3$ ($R^2$= 0.9998) and 0.01M $CaCl_2$ ($R^2$= 0.8580). The earthworm uptake of Zn and the desorbed amount of Zn ($q_{desorbed}$ = $q_0-q_{e,d}$) in MB soil were also linearly related ($R^2$ = 0.899). Our results implicate that the ecological risk assessment of heavy metals would be possible considering the relation between desorption behaviors and bioavailability to earthworm.

Effect of Age on Glucose Metabolism of Skeletal Muscle in Rats (흰쥐에서 연령이 골격근의 당 대사에 미치는 영향)

  • Jang, Eung-Chan;Youn, Woon-Ki;Lee, Suck-Kang
    • Journal of Yeungnam Medical Science
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    • v.18 no.1
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    • pp.94-100
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    • 2001
  • Background: It is doubtful that aging causes deteriorated glucose metabolism and insulin resistance of skeletal muscle. Some researchers had different results about it. So we have studied the mechanism responsible for the abnormal glucose tolerance associated with aging in rapidly growing and matured rats. Materials and Methods: Animals were used S.D. rats. Growing rats were 7 weeks old (BW: 160-190 gm) and matured rats were 28 weeks old (BW: 420-525 gm). Results: Fasting blood glucose and plasma insulin levels were significantly elevated in matured rat compared with growing rats. And during oral glucose tolerance test the glucose level was also significantly elevated in matured rats. These results confirmed an insulin resistant state of aging. Insulin levels at 30 minutes of oral glucose tolerance test was significantly elevated in growing rat. But at 120 minutes it was maintained at higher level in matured rats than in growing rats. It suggested the possibility of increased insulin secretion by initial stimulation of beta-cells in growing rats, and increased secretion and decreased catabolic rate of insulin in matured rats. Glucose uptake rate of soleus muscle in matured rats was lower than that of growing rats, but the difference was not statistically significant. The dose(insulin)-responsive(glucose uptake) curve of soleus muscle was only slightly deviated to the right side. Conclusion: Glucose metabolism of rat skeletal muscle was worsened by aging. The data of glucose uptake experiments suggested the possibility of insulin resistance of skeletal muscle in matured rats. but the mechanism of insulin resistance of skeletal muscle need further studies.

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Low Cycle Fatigue Behavior of 429EM Stainless Steel at Elevated Temperature (429EM 스테인리스강의 고온 저주기 피로 거동)

  • Lee, Keum-Oh;Yoon, Sam-Son;Hong, Seong-Gu;Kim, Bong-Soo;Lee, Soon-Bok
    • Transactions of the Korean Society of Mechanical Engineers A
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    • v.28 no.4
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    • pp.427-434
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    • 2004
  • Ferritic stainless steel is recently used in high temperature structures because of its good properties of thermal fatigue resistance, corrosion resistance, and low price. Tensile and low-cycle fatigue (LCF) tests on 429EM stainless steel used in exhaust manifold were performed at several temperatures from room temperature to 80$0^{\circ}C$. Elastic Modulus, yield strength, and ultimate tensile strength monotonically decreased when temperature increased. Cyclic hardening occurred considerably during the most part of the fatigue life. Dynamic strain aging was observed in 200~50$0^{\circ}C$, which affects the cyclic hardening behavior. Among the fatigue parameters such as plastic strain amplitude, stress amplitude, and plastic strain energy density (PSED), PSED was a proper fatigue parameter since it maintained at a constant value during LCF deformation even though cyclic hardening occurs considerably. A phenomenological life prediction model using PSED was proposed considering the influence of temperature on fatigue life.

The effect of fibroblast growth factor receptor inhibition on resistance exercise training-induced adaptation of bone and muscle quality in mice

  • Cho, Suhan;Lee, Hojun;Lee, Ho-Young;Kim, Sung Joon;Song, Wook
    • The Korean Journal of Physiology and Pharmacology
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    • v.26 no.3
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    • pp.207-218
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    • 2022
  • Aging in mammals, including humans, is accompanied by loss of bone and muscular function and mass, characterized by osteoporosis and sarcopenia. Although resistance exercise training (RET) is considered an effective intervention, its effect is blunted in some elderly individuals. Fibroblast growth factor (FGF) and its receptor, FGFR, can modulate bone and muscle quality during aging and physical performance. To elucidate this possibility, the FGFR inhibitor NVP-BGJ398 was administrated to C57BL/6n mice for 8 weeks with or without RET. Treatment with NVPBGJ398 decreased grip strength, muscular endurance, running capacity and bone quality in the mice. FGFR inhibition elevated bone resorption and relevant gene expression, indicating altered bone formation and resorption. RET attenuated tibial bone resorption, accompanied by changes in the expression of relevant genes. However, RET did not overcome the detrimental effect of NVP-BGJ398 on muscular function. Taken together, these findings provide evidence that FGFR signaling may have a potential role in the maintenance of physical performance and quality of bone and muscles.

An experimental study on hydrothermal degradation of cubic-containing translucent zirconia

  • Kengtanyakich, Santiphab;Peampring, Chaimongkon
    • The Journal of Advanced Prosthodontics
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    • v.12 no.5
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    • pp.265-272
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    • 2020
  • PURPOSE. The aims of this study were to investigate mechanical properties and hydrothermal degradation behaviour of the cubic-containing translucent yttrium oxide stabilized tetragonal zirconia polycrystal (Y-TZP). MATERIALS AND METHODS. Four groups of Y-TZP (T, ST, XT, and P), containing different amount of cubic crystal, were examined. Specimens were aged by autoclaving at 122℃ under 2 bar pressure for 8 h. Phase transformation was analyzed using X-ray diffraction (XRD) to measure phase transformation (t→m). Kruskal-Wallis test was used to determine the difference. Surface hardness, biaxial flexural strength, and fracture toughness in values among the experimental groups and verified with Wilcoxon matched pairs test for hardness values and Mann Whitney U for flexural strength and fracture toughness. RESULTS. XRD analysis showed no monoclinic phase in XT and P after aging. Only Group T showed statistically significant decreases in hardness after aging. Hydrothermal aging showed a significant decrease in flexural strength and fracture toughness in group T and ST, while group XT and P showed no effect of aging on fractural strength and fracture toughness with P<.05. CONCLUSION. Hydrothermal aging caused reduction in mechanical properties such as surface hardness, biaxial flexural strength, and fracture toughness of Y-TZP zirconia. However, cubic-containing zirconia (more than 30% by volume of cubic crystal) was assumed to have high resistance to hydrothermal degradation. Clinical significance: Cubic-containing zirconia could withstand the intraoral aging condition. It could be suggested to use as a material for fabrication of esthetic dental restoration.

The Effects of Physical Aging of PSF/AS4 Laminate on Fatigue (PSF/AS4 복합재료의 가속노화가 피로강도에 미치는 영향)

  • Kim, Hyung-Won
    • Composites Research
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    • v.19 no.4
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    • pp.1-6
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    • 2006
  • The effects of aging on fatigue of PSF/AS4 laminates tvas studied using the new energy release rate analysis. The analysis by the variational mechanics has been useful in providing fracture mechanics interpretation of matrix microcracking in cross-ply laminates. This paper describes the changes of the critical energy release rate ${\Delta}Gmc$(microcracking toughness) about the variation of the aging period during fatigue loading. The master plot by modified Pans-law gives a characterization of a material system's resistance to microcrack formation. PSF/AS4 $[0/902]_s$ laminates were aged at four different temperatures based on the glass transition temperature for 60 days. At all temperatures, the toughness decreased with aging time. The decrease of the toughness at higher temperature was faster than at lower temperature. To assess the effects of aging on fatigue, the unaged laminates were compared with the laminates which were aged for 60 days at $170^{\circ}C$ near $180^{\circ}C\;T_g$. The slope of dD/dN versus A 6u, of the aged laminates was lower than that of the unaged laminates. There was a significant shift of the aged data to formation of microcracks at the lower values of ${\Delta}G_m$.

A Study on the Physical Characteristics of the Low-voltage Circuit Breaker Based on the Accelerated Degradation Test (가속 열화 시험에 따른 저압용 차단기의 물리적 특성에 관한 연구)

  • Sin dong, Kang;Jae-Ho, Kim
    • Journal of the Korean Society of Safety
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    • v.37 no.6
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    • pp.1-8
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    • 2022
  • This study analyzed the characteristics of insulation resistance and operating time based on an accelerated degradation test of a low-voltage circuit breaker. The experimental sample used a molded case circuit breaker (MCCB) and an earth leakage circuit breaker (ELCB). After measuring the insulation resistance of the circuit breakers, the leakage current was affected by an external rather than an internal structure. Furthermore, the insulation resistance of the circuit breakers with accelerated degradation was measured using a Megger insulation tester. In the accelerated degradation test, aging times of five, ten, 15, and 20 years were applied according to a temperature derived using the Arrhenius equation. Circuit breakers with an equivalent life of ten, 15, and 20 years had increased insulation resistance compared to those with less degradation time. In particular, the circuit breaker with an equivalent life of ten years had the highest insulation resistance. Component analysis of the circuit breaker manufactured through an accelerated degradation test confirmed that the timing of the increase in insulation resistance and the time of additive loss were the same. Finally, after analyzing the operating time of the circuit breakers with degradation, it was confirmed that the MCCB did not change, but the ELCB breaker failed.

Causes of age-related sarcopenia and frailty: the role of exercise and nutrition for prevention (노화 관련 근감소증과 노쇠함의 원인과 예방을 위한 운동과 영양의 역할)

  • Byun, Yong-Hyun;Park, Woo-Young
    • Journal of the Korean Applied Science and Technology
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    • v.37 no.3
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    • pp.625-634
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    • 2020
  • The purpose of this study is not only to define and cause of sarcopenia and frailty due to aging, but also to explore prevention and delay through regular exercise and right nutrition. Sarcopenia and frailty are known to cause frailty, cachexia, osteoporosis, metabolic syndrome and early death due to decreased muscle mass and muscle function caused by aging. The two disease were related to nervous system damage and lack of protein synthesis within the muscles due to the increase in the amount of oxidative stress, and inadequate nutrition and lack of physical activity. It also emphasizes the role and importance of right nutrition and physical activity (such as aerobic exercise, resistance movement, etc) to prevent and improve such syndromes. Conclusions, it is in proposing the supply of high-quality protein, including regular exercise, as the most beneficial way to prevent and overcome aging-related sarcopenia and frailty.

Investigation into the Thermal Stability of Fluoropolymer Coating for Heat-Resistant Application (내열성 불소수지 코팅막의 열 안정성에 관한 연구)

  • Cho, Hey-Jin;Ryu, Ju-Hwan;Byun, Doo-Jin;Choi, Kil-Yeong
    • Polymer(Korea)
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    • v.29 no.1
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    • pp.96-101
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    • 2005
  • Fluoropolymer of PTFE and PFA etc. is a heat resistance polymeric material that it is known as that maximum continuous use temperature reaches for 260 $^{\circ}C$. It was observed that these polymers had the enough thermal stability so enough that it was kept by thermal aging of 280 $^{\circ}C$/7 weeks too in this study. However, such thermal stability means that bulk material property is kept such as mechanical strength, melting point and initial pyrolysis temperature etc. If these polymers are evaluate by coating property such as surface contact angle, surface morphology, surface scratch, thing that heat resistance is not enough was confirmed in this study. Thermal aging of flouropolymer coating was achieved by gear aging oven that the exchange rate of air was controlled, and the analysis results were indicating serious damage of surface morphology and adhesive strength on metal substrate.

Effects of Vulcanization Type end Temperature on Physical Properties of Natural Rubber Compounds (가황형태 및 온도가 천연고무 컴파운드의 물리적 특성에 미치는 영향)

  • Rhee, John-M.;Yoon, Chan-Ho;Huh, Yang-Il;Han, Seung-Cheol;Nah, Chang-Woon
    • Elastomers and Composites
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    • v.35 no.3
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    • pp.173-179
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    • 2000
  • Cure characteristics. tensile properties, and dynamic properties were investigated on the carbon black-filled natural rubber compounds, in which three typical vulcanization types conventional vulcanization(Conv), semi-efficient(Semi-EV), and efficient(EV) vulcanizations were used. The effects of vulcanization temperature on both the mechanical property and aging resistance of rubber compounds were also investigated. The Conv cure system showed a slightly slower rate of vulcanization than those of Semi-EV and EV ones. On the other hand, it showed a higher value in the maximum torque of cure curve. Higher tensile moduli were observed in Conv system than those in Semi-EV and EV ones, while lower elongation at break were obtained in Conv one. The tensile strength at break were found to be about the same for three cute systems. Hardness, modulus, and tensile strength decreased with increasing the vulcanization temperature, and the degree of changes in the properties was found to be smaller for EV and Semi-EV systems than that in Conv one. The EV system was found to be superior in thermal-aging resistance to Conv one.

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