• Title/Summary/Keyword: Aging

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Aging and Skin Aging (노화와 피부노화에 대한 고찰)

  • Nam Hae-jeong;Kim Yoon-bum
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.17 no.1
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    • pp.16-33
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    • 2004
  • In Oriental medicine, aging is just a natural process like change of seasons. Ancient Oriental people accepted it as a natural thing to be growing older and to die at last. The science of aging has advanced dramatically. In the last 2 decades, advances in genetics and molecular biology have led to extraordinary new understandings in how cells age, how apoptosis programs cells to die, and how neuroendocrinology plays a role in the lifespan of organisms. Today, the matter of primary concern about aging is a cellular and mitochondrial damage of human body induced by reactive oxygen species(ROS). The skin aging can be divided into two areas, intrinsic(chronologic)-aging and photo-aging. There are lots of photo damage about skin aging. The skin is increasingly exposed to ultraviolet(UV) irradiation in life. Therefore, the risk of photo-oxidative damage of the skin induced by reactive oxygen species(ROS) has increased substantially. Nowadays, many people believe that they can stop or at least delay the process of aging. There are lots of treatments that promise to slow the process of aging and the associated ailments. Many of these treatments, for example, exercise, Vit E, Vit C therapy, hormone therapy, restrict diet, are gradually being subjected to clinical trials. But in spite of all efforts, researches and investigations, there is no single method or treatment which is revealed to be truly effective for delaying progress of aging. Every methods insisted on effect for delaying aging process, has its dark side. All we can do is just keeping ourself healthy until the time of death.

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Effects of Dry- and Wet-ageing on Flavor Compounds and Eating Quality of Low Fat Hanwoo Beef Muscles

  • Ha, Yoonkyung;Hwang, Inho;Van Ba, Hoa;Ryu, Sangdon;Kim, Younghoon;Kang, Sun Moon;Kim, Jinhyoung;Kim, Yunseok;Cho, Soohyun
    • Food Science of Animal Resources
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    • v.39 no.4
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    • pp.655-667
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    • 2019
  • The present study aimed at investigating the effects of dry- and wet-aging methods on flavor compounds and sensory properties of low fat Hanwoo beef muscles. All the beef samples were obtained from 2-grade carcasses of Hanwoo cows. The beef samples used in the dry- and wet-aging methods were prepared in the forms of quarter beef (bone-in) and cuts (boneless), respectively. The dry-aging was carried out at $2^{\circ}C-4^{\circ}C$ and humidity of 65%-85%, while the wet-aging was done at $1^{\circ}C$ for 0, 20, 40, and 60 d. At each aging time, three muscles: longissmus thoracis (LT), glutaeusmedus (GM) and semimembranosus (SM) were taken from the corresponding quarters and cuts, and used for the flavor compounds and sensory analyses. Results showed that both aging methods significantly increased the concentrations of flavor compounds and total amount of all classes of the flavor compounds as the aging time increased (p<0.05). In the dry-aging method, the GM and SM muscles presented significantly higher total amounts of pyrazines and sulfur-containing compounds compared to the LT muscle (p<0.05). Both the aging methods improved the eating quality attributes, indicating by increased scores of sensorial attributes with increased aging time for all the muscles studied (p<0.05). However, compared to the wet-aging, the dry-aging method resulted in significantly higher scores of tenderness and flavor for the GM and SM muscles after 40 to 60 d. Thus, postmortem aging, especially the dry-aging method could be used to improve eating quality attributes (tenderness and flavor) of low fat beef muscles such as GM and SM.

Analysis on Spatial Pattern Changes of Aging Phenomenon and Relation between Aging Population and Regional Characteristics (고령화 현상의 공간적 패턴 변화와 지역특성과의 관계 분석)

  • Lee, Jimin
    • Journal of Korean Society of Rural Planning
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    • v.22 no.4
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    • pp.139-146
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    • 2016
  • Aging phenomenon is an important issue in Korea national policy. This aging phenomenon depends on the social and environmental characteristics of regions. Also aging phenomenon and regional characteristics have spatial dependency. The purpose of this study is to discover the spatial changes in aging population rate and to find local factors of regional aging phenomenon considering spatial autocorrelation. For spatial analysis of ageing phenomenon, local Moran's I and Geographically Weighted Regression (GWR) were applied. As the results, the most significant changes of aging phenomenon appeared between 2000 and 2005, and most of hot-spot regions (aged regions) were distributed in Jullanam-do and Jullabuk-do. The results of GWR (R-square: 0.681) shows that total fertility rate, the number of doctor per 1,000 people and forest area rate have positive relation with aging population rate, but the number of private academy per 1,000 people has negative relation.

A Study on the Dynamics of the Local Government Finance in Accordance with the Aging Population (고령화에 따른 지방재정의 동태성 분석)

  • Choi, Nam-Hee
    • Korean System Dynamics Review
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    • v.13 no.4
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    • pp.5-31
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    • 2012
  • This paper aims at investigating the dynamics between aging population and local finance. In recent years, the aging rate has been accelerating the pace. The trend implies that Korea is moving towards the aging society, presumably, with unprecedented speed in the world. Aging society's biggest problems are centered around the explosive growth of the financial needs. In particular, these problems are apt to appear more seriously in local governments, as most of them are confronted with high level of aging population and poor financial bases. Firstly, it analyzes how the population structure in the local government impacts local finance, income and expenditure. Based upon in-depth literature reviews, this study examines variables related to aging population and local fiance. Secondly, it focuses on a series of positive and negative feedback loops which would reveal the essence of the mutual interaction structure between aging population and local governments' fiscal behaviors.

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Analyses on Electrical-Mechanical Characteristics of Environment-friendly Transformer Insulating Material by Accelerated Thermal Aging (가속 열 열화에 따른 환경친화형 변압기 절연물의 전기적-기계적 특성 분석)

  • Shim, Myeong-Seop;An, Jung-Sik;Choi, Sun-Ho;Jeong, Jung-Il;Lee, Tae-Ho;Huh, Chang-Su
    • The Transactions of The Korean Institute of Electrical Engineers
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    • v.59 no.10
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    • pp.1832-1838
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    • 2010
  • Aging of transformer insulating material in natural ester insulating oil is compared to that in conventional transformer oil. Aging of insulating paper and insulating oil have been studied by performing accelerated thermal aging test. Sealed aging test vessels containing cooper, laminated core, Kraft paper and insulating oil(natural oil or mineral oil) were aged at $140^{\circ}C$ for 500, 1000, 1500 and 2000 hours. Insulating oils after aging are investigated with total acid number, breakdown voltage and viscosity. Also, degradation of insulating paper after aging is determined using breakdown voltage and mechanical strength. Accelerated aging studies demonstrate a slower aging rate for natural ester insulating oil compared to the rate for conventional mineral oil.

Non-Coding RNAs in Caenorhabditis elegans Aging

  • Kim, Sieun S.;Lee, Seung-Jae V.
    • Molecules and Cells
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    • v.42 no.5
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    • pp.379-385
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    • 2019
  • Non-coding RNAs (ncRNAs) comprise various RNA species, including small ncRNAs and long ncRNAs (lncRNAs). ncRNAs regulate various cellular processes, including transcription and translation of target messenger RNAs. Recent studies also indicate that ncRNAs affect organismal aging and conversely aging influences ncRNA levels. In this review, we discuss our current understanding of the roles of ncRNAs in aging and longevity, focusing on recent advances using the roundworm Caenorhabditis elegans. Expression of various ncRNAs, including microRNA (miRNA), tRNA-derived small RNA (tsRNA), ribosomal RNA (rRNA), PIWI-interacting RNA (piRNA), circular RNA (circRNA), and lncRNA, is altered during aging in C. elegans. Genetic modulation of specific ncRNAs affects longevity and aging rates by modulating established aging-regulating protein factors. Because many aging-regulating mechanisms in C. elegans are evolutionarily conserved, these studies will provide key information regarding how ncRNAs modulate aging and lifespan in complex organisms, including mammals.

The Effects of Emotional Happiness on Aging Preparation

  • Jung, Hae-ok;Kim, Jung-ae
    • International Journal of Advanced Culture Technology
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    • v.6 no.3
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    • pp.59-68
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    • 2018
  • This study was a cross-sectional descriptive study of the effects of emotional happiness on aging preparation for 45-60 year olds. Participants of this study were 312 volunteers and data was collected online, the collection period was from May 15, 2018 to May 31, 2018. The tools used in the research were the emotional happiness developed by Watson et al (1988) et al., the aging preparation developed by JH Lee (2009). Analysis was done using t-test, ANOVA, Pearson correlation, and regression by SPSS 18.0. As a result of the analysis, 84.0% of participants felt physically healthy and 89.8% felt mental health. The spouses of participants were physically 83.4% healthy and mentally 82.7% healthy. The correlation between emotional happiness, health cognition and aging preparation showed that physical health had a correlation with mental health (r = .482, p <0.01) and emotional happiness (r = .369, p <0.01), economic aging preparation (r = .411, p <0.01), social aging preparation (r = .119, p <0.01). Mental health was correlated with emotional happiness (r = .491, p <0.01), economic aging preparation (r = .411, p <0.01) and social aging preparation. Difference between emotional happiness and retirement preparation according to presence or absence of disease, emotional happiness (t = -4.503, p <0.01) and economic aging preparation (t = -4.960, p <0.01) were statistically significant. Emotional happiness affects the preparation of old age, emotional happiness affects to physical aging preparation under statistical significance (F=25.191, p<0.01), economic aging preparation (F=1131.783, p<0.01), and social aging preparation (F=147.672, p<0.01) which were sub components of aging preparation. Emotional happiness showed a 7.5% effect on the preparation of physical aging, 78.4% on economic aging preparation and 32.3% on social aging preparation. Based on the above results, it can be concluded that physical health and mental health are related to emotional happiness, economic aging preparation, and social aging preparation. And also these results can be inferred that the illness causes emotional less feeling of happiness and economic difficulty. Based on the results of this study, emotional well - being influences the retirement preparation significantly at statistical significance. Therefore, if the concept of emotional happiness is introduced to the old-age preparation program, it will be more client centered program.

Multi-phase Accelerating Test Method of Thermal Aging Considering Heat Generation of Electric Equipment (전기기기의 발열을 고려한 다단계 가속열노화 방법)

  • Lim, Byung-Ju;Park, Chang-Dae;Chung, Kyung-Yul
    • The KSFM Journal of Fluid Machinery
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    • v.16 no.5
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    • pp.18-23
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    • 2013
  • Thermal aging test is performed to qualify the life time of equipment in thermally aged condition. Due to long life time more than 10 years like as in power plant, the equipment is subjected to the accelerated thermal aging condition which is able to shorten the long aging test period by increasing aging temperature. Normally, conservatism of thermal aging test causes to impose unbalanced and excessive thermal load on components of the equipment, and deformation and damage problems of the components. Additionally, temperature rise of each component through heat generation of the electric equipment leads to long-term problem of the test period. Multi-phase accelerating aging test is to perform thermal aging test in multiple aging conditions after dividing into groups with various components of equipment. The groups might be classified considering various factors such as activation energy, temperature rise, glass transition temperature and melting temperature. In this study, we verify that the multi-phase accelerating aging test method can reduce and equalize the thermal over load of the components and shorten aging test time.

The Association Between Expectations Regarding Aging and Health-Promoting Behaviors Among Korean Older Adults (노화에 대한 기대수준이 노인의 건강증진행위에 미치는 영향)

  • Kim, Su-Hyun
    • Journal of Korean Academy of Nursing
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    • v.37 no.6
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    • pp.932-940
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    • 2007
  • Purpose: This study was performed to measure expectations regarding aging among community-residing older adults, identify sociodemographic characteristics associated with the level of expectations regarding aging, and examine whether expectations regarding aging were associated with health-promoting behaviors. Methods: Data was collected by using questionnaires of a short version of the Expectations Regarding Aging Survey (ERA-18) and Health Promoting Lifestyle Profile II (HPLP II) from 99 older adults who resided in the community of Kyunggi, Daegu, and Kyungpook province. Results: More than 75% of the participants reported that it was an expected part of aging to have more aches and pains, to become depressed, and to become more forgetful. The mean score of expectations regarding aging was $23.15{\pm}17.80$ (possible range 0-100). The old-old, women, those with less education, less monthly allowance and poor health status had lower expectations regarding aging than other elderly. After controlling for sociodemographic characteristics and perceived health, expectations regarding aging were independently associated with health-promoting behaviors in older adults. Conclusion: The findings demonstrate that older Korean adults have low expectations regarding aging, and expectations regarding aging influence health-promoting behaviors.

Comparison of Meat Quality Characteristics of Wet- and Dry-aging Pork Belly and Shoulder Blade

  • Hwang, Young-Hwa;Sabikun, Nahar;Ismail, Ishamri;Joo, Seon-Tea
    • Food Science of Animal Resources
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    • v.38 no.5
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    • pp.950-958
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    • 2018
  • The physicochemical characteristics and oxidative stability of wet-aged and dry-aged pork cuts were investigated at different aging periods (1, 7, 14 and 21 d). Samples were assigned into four groups in terms of shoulder blade-wet aging (SW), shoulder blade-dry aging (SD), belly-wet aging (BW), and belly-dry aging (BD). SD showed significantly higher pH at 21 d of aging than the other samples. Wet-aged cuts had significantly higher released water (RW) %, lightness ($L^*$) and shear force compared to the dry-aged meats. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) analysis showed greater degradation of proteins for dry-aged cuts than the wet-aged cuts. At the end of aging, wet-aged cuts showed significantly lower thiobarbituric acid-reactive substances (TBARS) value than the dry-aged samples, indicating higher oxidative stability for wet-aged pork cuts. However, dry-aging led to higher degradation of proteins resulting in increased water-holding capacity (WHC) and decreased shear force value.