• The Plant Pathology Journal
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• v.27 no.1
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• pp.14-19
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• 2011

Early blight of potato, caused by Alternaria solani, is a ubiquitous disease in many countries around the world. Our previous screening of several Iranian potato cultivars found that significant variation in resistance phenotypes exists between two cultivars: resistant 'Diamond' and susceptible 'Granula'. Our previous analysis of five different pathogen isolates also identified varying degrees of aggressiveness regardless of the host cultivar. Here, a bioassay was used to study the role of liquid culture exudates produced in vitro on pathogenicity and elicitation of disease symptomology in seedlings as well as detached leaves. Responses of host genotypes to the exudates of the two A. solani isolates were significantly different. Detached leaves of the resistant cultivar 'Diamond' elicited fewer symptoms to each isolate when compared to the susceptible cultivar 'Granula'. Interestingly, the phytotoxicity effect of the culture filtrate from the more aggressive isolate A was higher than from isolate N suggesting an increased concentration or strength of the toxins produced. Our results are significant because they indicate a correlation between symptoms elicited by A. solani phytotoxins and their aggressiveness on the host.

• Molecules and Cells
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• v.42 no.7
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• pp.530-545
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• 2019

Tumor cells can vary epigenetically during ionizing irradiation (IR) treatment. These epigenetic variegations can influence IR response and shape tumor aggressiveness. However, epigenetic disturbance of histones after IR, implicating in IR responsiveness, has been elusive. Here, we investigate whether altered histone modification after IR can influence radiation responsiveness. The oncogenic CXCL12 mRNA and protein were more highly expressed in residual cancer cells from a hepatoma heterotopic murine tumor microenvironment and coculture of human hepatoma Huh7 and normal IMR90 cells after radiation. H3K4 methylation was also enriched and H3K9 methylation was decreased at its promoter region. Accordingly, invasiveness and the subpopulation of aggressive $CD133^+/CD24^-$ cells increased after IR. Histone demethylase inhibitor IOX1 attenuated CXCL12 expression and the malignant subpopulation, suggesting that responses to IR can be partially mediated via histone modifications. Taken together, radiation-induced histone alterations at the CXCL12 promoter in hepatoma cells are linked to CXCL12 upregulation and increased aggressiveness in the tumor microenvironment.

• The Journal of Asian Finance, Economics and Business
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• v.10 no.1
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• pp.223-232
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• 2023

This study desires to examine the impact of five dimensions of entrepreneurial (EO) orientation (innovation, competitive aggressiveness, proactiveness, risk-taking, autonomy) on the operation of women-owned SMEs; the author conducted a case study in Vietnam. How will each dimension of EO affect women-owned SMEs' performance? This study aims to seek the answer to these questions. A survey research design and a theoretical framework have been developed for all factors in the current context. A simple random sampling technique was applied in 300 SMEs in some provinces of Vietnam through a survey questionnaire, and a total of 258 valid responses were assessed as appropriate. The obtained data was analyzed by using SPSS 20.0. Cronbach's α test and factor analysis have been carried out to test the reliability of data and validate the hypothesis. Research results show that innovation, competitive aggressiveness, proactiveness, and autonomy positively affect business performance, while risk-taking negatively affects business performance. The results suggest that female business owners should know how to improve each dimension of the entrepreneurial in line with its context. Research results are important implications for Government administrative agencies for businesses to consult and introduce effective support policies. It is recommended that similar studies be replicated to confirm this result.

• The Journal of Small Business Innovation
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• v.19 no.3
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• pp.17-42
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• 2016

Financial Accounting Standards Board (FASB) Interpretation No. 48 (FIN 48), Accounting for Uncertainty in Income Taxes: An interpretation of FASB Statement No. 109, requires firms to evaluate uncertain tax positions and disclose information on their liabilities for these positions, unrecognized tax benefits (UTBs). We analyze the FIN 48 disclosures for calendar-year-end Korean companies listed on NYSE and NASDAQ and examine the Korean firms' tax aggressiveness utilizing the UTBs. The results suggest that stock exchange and firm size do not play a role in the Korean firms' tax aggressiveness, contrary to the matched U.S. firms and that the Korean firm in the miscellaneous retail industry is more tax aggressive than the firms in the communications, depository institutions and business services. In addition, we find evidence that the Korean firms are less tax aggressive than the matched U.S. firms. We also examine the Korean firms' tax avoidance tendencies using other measures of avoidance, leading to mixed results. Finally, we examine the association between the UTBs and other measures of tax avoidance and find a significant and negative association between the UTBs and the long-run cash effective tax rate.

• Journal of Convergence for Information Technology
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• v.9 no.6
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• pp.153-163
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• 2019

The purpose of this study is to research the effect of life satisfaction on young people at an early age and the impact of media on behavioral aggressiveness during this process. To this end, a group of primary schools located in Jiangnan and Jiangbei in the Seoul area and the Nanjing Road in the city were selected and 290 early youths from grades 4-6 of elementary school were chosen as specimens of structural equations. The results indicate that firstly, the personal causes of early youth have a positive (+) effect on the self-esteem life satisfaction and negative (-) impact on liquidity aggressiveness. Secondly, depression has a negative impact on life satisfaction, while action aggressiveness has no effect. Thirdly, the mobility aggression of early youth has a negative impact on life satisfaction (-), and there is a partial media relationship between self-esteem and life satisfaction. However, there is no media relationship between depression and life satisfaction. Based on the above research results, the project of improving youth early life satisfaction and reducing mobile aggression was proposed.

• The Journal of Korean Physical Therapy
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• v.3 no.1
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• pp.59-73
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• 1991

The purpose of this study was to phychosomatic health status of physical therapy college mans. 130college mans analysis sex, habitation, religion, blood type, drinking, somoking by the todai health index questionaire. THI was modified front cornell medical index. Physical therapy college man showed complain score (E) Nervousness. (J) Mental irritability. (H) Impulsiveness. (F) Aggressiveness. (G) Irregular life (I), (L) Multiple subjective symtom(I), Live scale(L), (K) Depression. (C) Digestive, (A), (B) Respiratory(A), Eye and Skin(B). (D) Mouth and Anus.

• Proceedings of the Korean Society of Toxicology Conference
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• 2003.10b
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• pp.141-141
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• 2003

Ras expression has been suggested as a marker for tumor aggressiveness of breast cancer, including the degrees of invasion and tumor recurrence. We previously showed that p38 MAPK is a key signaling molecule differentially regulated by H-ras and N-ras, leading to H-ras-specific cell invasive and migrative phenotypes in human breast epithelial cells (Cancer Res.: 63, 5454-5461, 2003).(omitted)

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.170.2-170.2
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• 2003

Ras expression has been suggested as a marker for tumor aggressiveness of breast cancer, including the degrees of invasion and tumor recurrence. We previously showed that p38 MAPK is a key signaling molecule differentially regulated by H-ras and N-ras, leading to H-ras-specific cell invasive and migrative phenotypes in human breast epithelial cells (Cancer Res: 63, 5454-5461, 2003). In this study, we further investigated the role of p38 MARK pathway in the induction of metastatic potential in MCF10A cells as a "gain of function" study. (omitted)

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.20 no.1
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• pp.17-22
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• 2009

Objectives : A higher level of aggression has been reported for children with attention-deficit/hyperactivity disorder (ADHD) than for non-ADHD children. Aggression was shown to have a negative effect on the social functioning of children with ADHD. The ability to recognize facial emotion expression has also been related to aggression. In this study, we examined whether impulsivity and dysfunctional recognition of facial emotion expression could explain the aggressiveness of children with ADHD. Methods : 67 children with ADHD participated in this study. We measured the ability to recognize facial emotion expression by using the Emotion Recognition Test (ERT) and we measured aggression by the T score of the aggression subscale of the Child Behavior Checklist (CBCL). Impulsivity was measured by the ADHD diagnostic system (ADS). Results : The teacher rated level of aggression was related to the score of recognizing negative affect. After controlling for the effect of impulsivity, this relationship is not significant. Only the score of the visual commission errors ex plained the level of aggression of children with ADHD. Conclusion : Impulsivity seems to have a major role in explaining the aggression of children with ADHD. The clinical implication of this study is that effective intervention for controlling impulsivity may be expected to reduce the aggression of children with ADHD.

• Journal of the Korean Society of Earth Science Education
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• v.6 no.3
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• pp.196-206
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• 2013

The purpose of this study was to analyze perfectism, interpersonal characteristic between the gifted & talented students and the general. The subject of this study were 112 the gifted students and 120 the general. They answered the questions about perfectism and interpersonal characteristic. To compare the gifted and general students' tendency, collected data was classified by their gender and grade. And correlation analysis was done in oder to analyze the relation between the gifted students' perfectism and interpersonal characteristic. The important results of this study were as follows. First, the grade gap of perfectism was not meaningful in both groups. Otherwise, the gender gap of perfectism was meaningful in both groups. Female's perfectism was higher than male's. And the gifted students' perfectism was higher than the general students'. Second, Differently, the gender gap of interpersonal characteristic was meaningful in the same group. Female had higher positive social-relationship, expression tendency than male. But female had lower competition-aggressiveness propensity than male. In the general group, the 6th grade students showed more positive role, social-relationship than 5th grade. And male showed more competition-aggressiveness propensity than female. Comparing the gifted and the general, the gifted had more dominant-superior, exhibitionistic-narcissistic propensity. It could be a reason of the gifted students' social problem. Third, among self-oriented perfectism and dominant-superior, independent-responsible propensity had meaningful correlation. Also socially-prescribed perfectism had influenced on dominant-superior, sociability-friendliness, exhibitionistic-narcissistic propensity.