• Bulletin of the Korean Chemical Society
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• v.34 no.11
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• pp.3451-3455
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• 2013

Single-crystalline silicon nanowires (SiNWs) were fabricated by using an electroless metal-assisted etching of bulk silicon wafers with silver nanoparticles obtained by wet electroless deposition. The etching of SiNWs is based on sequential treatment in aqueous solutions of silver nitrate followed by hydrofluoric acid and hydrogen peroxide. SEM observation shows that well-aligned nanowire arrays perpendicular to the surface of the Si substrate were produced. Free-standing SiNWs were then obtained using ultrasono-method in toluene. Alkyl-derivatized SiNWs were prepared to prevent the aggregation of SiNWs and obtained from the reaction of SiNWs and dodecene via hydrosilylation. Optical characterizations of SiNWs were achieved by FT-IR spectroscopy and indicated that the surface of SiNWs is terminated with hydrogen for fresh SiNWs and with dodecyl group for dodecyl-derivatized SiNWs, respectively. The main structures of dodecyl-derivatized SiNWs are wires and rods and their thicknesses of rods and wire are typically 150-250 and 10-20 nm, respectively. The morphology and chemical state of dodecyl-derivatized SiNWs are characterized by scanning electron microscopy, transmission electron microscopy, and X-ray photoelectron spectroscopy.

• International Journal of Advanced Culture Technology
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• v.6 no.4
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• pp.109-115
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• 2018

Garlic is a medicinal plant used throughout the world for its anti-inflammatory, antioxidant, and antiplatelet activities. Chitosan is a natural polysaccharide obtained from chitin, and derivatives of chitosan have been shown to inhibit platelet aggregation and adhesion. We hypothesized that fermented preparations of these products may possess stronger antiplatelet effects than the non-fermented forms owing to the increased bioavailability of the bioactive compounds produced during fermentation. Therefore, we compared these compounds via in vitro and ex vivo platelet aggregation assays by using standard light transmission aggregometry and ex vivo granule secretions from rat platelets. We found that fermented preparations exerted more potent and significant inhibition of platelet aggregation both in vitro and ex vivo. Likewise, ATP release from dense granules of platelets was also significantly inhibited in fermented preparation-treated rat platelets compared to that in non-fermented preparation-treated ones. We concluded that fermented preparations exerted more potent effects on platelet function both in vitro and ex vivo, possibly as a result of the increased bioavailability of active compounds produced during fermentation. We therefore suggest that fermented products may be potent therapeutics against platelet-related CVDs and can be used as antiplatelet and antithrombotic agents.

• Korean Journal of Veterinary Research
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• v.36 no.4
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• pp.873-886
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• 1996

For better understanding the interrelationship of hemorrhage and aggregation mechanism, cyclopiazonic acid(CPA) known as promoting the aggregation of platelet, aflatoxin $B_1(AFB_1)$ inhibiting platelet aggregation were used as toxic mycotoxins in these studies. In order to investigate the potential role of prostaglandin metabolism on the platelet aggregation, a variety of prostaglandin metabolites such as $PGF_{2{\alpha}}$, $PGE_2$ and $TXB_2$ were measured in homogenized rabbit platelets by TLC and LSC. And the role of $Ca^{{+}{+}}$ on the platelet aggregation was investigated by flow cytometer. Finally, the morphological effects of mycotoxins on platelet were determined by transmission electron microscope. The results and conclusions obtained from these studies are: 1) CPA induced no changes but $AFB_1$ increased $PGE_2$ and $TXB_2$. 2) CPA promoted ADP, collagen, thrombin, A.A., and PAF-induced $Ca^{{+}{+}}$ release. $AFB_1$, however, decreased $Ca^{{+}{+}}$ level except collagen-induced $Ca^{{+}{+}}$ release. When the calcium blocker, verapamil, was used, CPA decreased thrombin-induced $Ca^{{+}{+}}$ release and increased collagen, ADP, PAF and A.A.-induced $Ca^{{+}{+}}$ release. $AFB_1$ in contrast decreased the all factors induced $Ca^{{+}{+}}$ release. 3) $AFB_1$ did not induce any ultrastructural changes except large vacuole formation in a few platelets. And CPA also did not induce any changes except moderate shape change, indicator of platelet activation. In conclusion, CPA promoted platelet aggregation by the increases of $Ca^{{+}{+}}$ release but had no changes in A.A. metabolites. Antiaggregating effects of $AFB_1$ may be due to decreases of $Ca^{{+}{+}}$ release and increases of $PGE_2$ and $PGF_{2{\alpha}}$ formation. These data provide the basis for the future study of mobilization and function of $Ca^{{+}{+}}$ in platelet aggregation.

• Journal of the Korea Society of Computer and Information
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• v.22 no.3
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• pp.115-122
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• 2017

In this paper, we propose an adaptive data aggregation and compression scheme for wireless sensor networks with energy-harvesting nodes, which increases the amount of data arrived at the sink node by efficient use of the harvested energy. In energy-harvesting wireless sensor networks, sensor nodes can have more than necessary energy because they harvest energy from environments continuously. In the proposed scheme, when a node judges that there is surplus energy by estimating its residual energy, the node compresses and transmits the aggregated data so far. Conversely, if the residual energy is estimated to be depleted, the node turns off its transceiver and collects only its own sensory data to reduce its energy consumption. As a result, this scheme increases the amount of data collected at the sink node by preventing the blackout of relay nodes and facilitating data transmission. Through simulation, we show that the proposed scheme suppresses the occurrence of blackout nodes and collect the largest amount of data at the sink node compared to previous schemes.

• Journal of Physiology & Pathology in Korean Medicine
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• v.30 no.1
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• pp.33-39
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• 2016

Alzheimer's disease(AD), one of the most common forms of dementia, is characterized pathologically by the presence of intracellular neurofibrillary tangles and deposition of β-amyloid(Aβ) peptides of 40-42 residues. Aβ has been believed to be neurotoxic and now is also considered to have a role on the mechanism of memory dysfunction. Only a few acetylcholinesterase(AChE) inhibitors have been developed for treatment of AD, although the numbers of patients are rapidly increasing within aging society. Here, we show that ethanol extract of Rosae Rugosae Flos(RR) or its butanol fraction reduce the enzyme activity of AChE and BACE1(β-site APP cleaving enzyme 1). Furthermore, We found that RR inhibits Aβ aggregation and removes Aβ aggregates by Transmission electron microscopy(TEM). In addition, RR reduces the free radical of 2, 2-diphenyl-1-picrylhydrazyl(DPPH). We suggest that Rosae Rugosae Flos may be useful as a herbal medicine to treat AD.

• Journal of Communications and Networks
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• v.14 no.4
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• pp.443-450
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• 2012

As for cluster-based wireless sensor networks (WSNs), cluster lifetime is one of the most important subjects in recent researches. Besides reducing the energy consumptions of the clusters, it is necessary to make the clusters achieve equal lifetimes so that the whole network can survive longer. In this paper, we focus on the cluster lifetimes in multi-hop WSNs with cooperative multi-input single-output scheme. With a simplified model of multi-hop WSNs, we change the transmission schemes, the sizes and transmission distances of clusters to investigate their effects on the cluster lifetimes. Furthermore, linear and uniform data aggregations are considered in our model. As a result, we analyze the cluster lifetimes in different situations and discuss the requirements on the sizes and transmission distances of clusters for equal lifetimes.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.48 no.10
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• pp.43-52
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• 2011

In this paper, we propose the architecture of the policy-based emergency bio data transmission for the smart healthcare service. the medical staff can quickly and accurately monitor the emergency bio data of the remote patient through the proposed architecture. The proposed system consists of three parts: IEEE 11073-based agents and managers performing the aggregation function and transmission function of the bio data; the emergency management server performing the converting function between IEEE 11073 and HL7 and auto-diagnosis function of the policy-based; HL7 medical system based on HL7. Finally, by implementing the proposed system, we shows that the aggregation of the bio data and management of the emergency bio data in the smart healthcare service are possible.

• The Journal of the Korea institute of electronic communication sciences
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• v.9 no.6
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• pp.695-701
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• 2014

Blackhole attacks having a unauthorized change of routing data will cause critical effects for transmission performance. The transmission performance will be improved to the a certain level by using or having IDS(Intrusion Detection System)/IPS(Intrusion Prevention System) as countermeasures to blackhole attacks. In this papar, the effects of IDS to ene-to-end performance of packet aggregation transmission are analyzed on MANET(Mobile Ad-hoc Network) with IDS under blackhole attacks. MANET simulator based on NS-2 is used to analyze performance parameters as MOS, connection ratio, delay and packet loss rate as standard performance parameters, an another performance factor which is suggested in this paper. VoIP(Voice over Internet Protocol) traffics, one of voice services, is used for performance analysis. A suggestion for IDS implementation on MANET with packet aggregations under blackhole is shown as one of results.

• Journal of Broadcast Engineering
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• v.20 no.2
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• pp.300-309
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• 2015

In IEEE 802.11n WLANs(Wireless Local Area Networks), to support high throughput, MAC(Media Access Control) layer adopts A-MSDU(Aggregate-MAC Service Data Unit) and A-MPDU(Aggregate-MAC Protocol Data Unit). Generally, as the A-MPDU uses a selective retransmission capability, A-MPDU provides higher throughput than A-MSDU. However, although A-MPDU uses the selective re-transmission capability, if the size of MPDU within A-MPDU is smaller than the size of minimum MPDU starting spacing, A-MPDU can reduce throughput because of the overhead of retransmission owing to the addition of delimiter, that is a dummy MPDU. Therefore, to overcome the above problem, two-level Aggregation method, where the small MPDU within A-MPDU is replaced by not delimiter but A-MSDU, has been introduced. In the two-level Aggregation method, the existing re-transmission scheme retransmits only A-MPDU, but if the size of retransmission data is smaller than the size of the minimum MPDU starting spacing, the proposed retransmission scheme retransmits the aggregated retransmission data and MSDUs. Therefore, we know that the proposed retransmission scheme have better throughput that the existing retransmission scheme.

• Proceedings of the Korea Information Processing Society Conference
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• 2007.05a
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• pp.1294-1296
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• 2007

The IEEE 802.11 DCF forces neighboring nodes of an active transmitter to switch into inactive state. This conservative nature brings frame latency at transmitter neighborhood. This work exploits the IEEE 802.11n Frame Aggregation scheme to allow simultaneous transmissions from nodes that are neighbors to each-other. This is accomplished by the synchronization of control and data transmissions in slots of fixed length. Proposed scheme reduces the frame latency and improves aggregated network throughput.