• Korean Journal of Veterinary Research
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• v.18 no.2
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• pp.87-95
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• 1978

Election microscopic investigation were conducted on the mature mouse (B.W. about 25g) liver which was treated with Ginseng water extract during three, six and nine days respectivelly after carbon tetracholride injection into abdominal cavity. The results obtained were as follows: The liver cells of control group treated with carbon tetrachloride alone were restored slowly. The liver cells of experimental group treated with Ginseng water extract after carbon tetrachloride injection, however, were shown the appearance of well-developed ${\gamma}-ER$ and Golgi complex, marked aggregation of glycogen particles, and a number of large lipid droplets which are attached markedly with glycogen particles as compared to the control group. As these findings, it could be suggested that Ginseng gives an activation to restore the damaged liver cells.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.3
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• pp.1119-1143
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• 2014

Lightweight trust mechanism with lightweight cryptographic primitives has emerged as an important mechanism in resource constraint wireless sensor based mobile devices. In this work, outlier detection in lightweight Mobile Ad-hoc NETworks (MANETs) is extended to create the space of reliable trust cycle with anomaly detection mechanism and minimum energy losses [1]. Further, system is tested against outliers through detection ratios and anomaly scores before incorporating virtual programmable nodes to increase the efficiency. Security in proposed system is verified through ProVerif automated toolkit and mathematical analysis shows that it is strong against bad mouthing and on-off attacks. Performance of proposed technique is analyzed over different MANET routing protocols with variations in number of nodes and it is observed that system provide good amount of throughput with maximum of 20% increase in delay on increase of maximum of 100 nodes. System is reflecting good amount of scalability, optimization of resources and security. Lightweight modeling and policy analysis with lightweight cryptographic primitives shows that the intruders can be detection in few milliseconds without any conflicts in access rights.

• Toxicological Research
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• v.29 no.2
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• pp.129-135
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• 2013

Salmonella is one of the major pathogenic bacteria that cause food poisoning. This study investigated whether heat-killed as well as live Lactobacillus protects host animal against Salmonella infection. Live and heat-killed Lactobacillusacidophilus was administered orally to Sprague-Dawley rats for 2 weeks before the rats were inoculated with Salmonella. Rise in body temperature was moderate in the group that was treated with heat-killed bacteria as compared to the Salmonella control group. The mean amount of feed intake and water consumption of each rat in the heat-killed bacteria group were nearly normal. The number of fecal Salmonellae was comparable between the live and the heat-killed L. acidophilus groups. This finding shows that L. acidophilus facilitates the excretion of Salmonella. Moreover, the levels of pro inflammatory cytokines, including tumor necrosis factor (TNF)-alpha and interleukin (IL)-1 beta, in the heat-killed L. acidophilus group were significantly lower when compared to the levels in the Salmonella control group. These results indicate that nonviable lactic acid bacteria also could play an important role in preventing infections by enteric pathogens such as Salmonella.

• Korean Journal of Materials Research
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• v.18 no.9
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• pp.503-506
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• 2008

The effect of silver nanoparticles (NPs) incorporation on the electronic properties of poly (3, 4-ethylenedioxythiphene) : poly(styrenesulfonate) (PEDOT : PSS) films was investigated. The surface of silver NPs was stabilized with trisodium citrate to control the size of silver NPs and prevent their aggregation. We obtained ca. 5 nm sized silver NPs and dispersed NPs in PEDOT : PSS solution. Sheet resistance, surface morphology, bonding state, and work function values of the PEDOT : PSS films were modified by silver NPs incorporation as well as annealing temperature. Sodium in silver NPs solution could lead to a decrease of work function of PEDOT : PSS; however, large content of silver NPs have an effect on the increase in work function, resulting from charge localization on the silver NPs and a decrease in the number of charge-trapping-related defects by chemical bond formation.

• Korean Journal of Pharmacognosy
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• v.37 no.2 s.145
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• pp.97-102
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• 2006

Garlic(Allium sativum Linn) is widely used as a common condiment for a variety of foods and beverages. It has been well known that fresh garlic and garlic supplement of commercial preparations have various therapeutic properties including antimicrobial activity, antiplatelet aggregation, antihypertension, and cholesterol-lowering effects, which contribute to its increasing uses for an alternative medicine. Allicin(diallyl thiosulfinate), the major bioactive components of garlic, is formed by alliinase cleavage of the naturally occurring alliin upon crushing or mincing of garlic, and is the progenitor of a number of other products, such as diallyl disulfide. CYP3A4, heme-containing monooxygenase, is a key enzyme responsible for drug metabolism. Therefor, in the present study, we isolated and examined the compounds with CYP3A4-inhibiting activities from garlic. Among EtOAc extracts of garlic, we found that N-p-coumaroyltyramine and N-feruloyltyramine showed remarkable CYP3A4-inhibiting activities, compared to diallyl disulfide. Structures of the isolated active compounds were established by chemical and spectroscopic means.

• Journal of Microbiology and Biotechnology
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• v.26 no.10
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• pp.1808-1816
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• 2016

As a scaffolding subunit of the PIK3C3/VPS34 complex, Beclin 1 recruits a variety of proteins to class III phosphatidylinositol-3-kinase (VPS34), resulting in the formation of a distinct PIK3C3/VPS34 complex with a specific function. Therefore, the investigation of a number of Beclin 1 domains required for the protein-protein interactions will provide important clues to understand the PIK3C3/VPS34 complex, of which Beclin1-VPS34 interaction is the core unit. In the present study, we have designed a bacterial overexpression system for the Beclin 1 domain corresponding to VPS34 binding (Vps34-BD) and set up the denaturing purification protocol due to the massive aggregation of Vps34-BD in Escherichia coli. The expression and purification conditions determined in this study successfully provided soluble and functional Vps34-BD.

• Ocean and Polar Research
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• v.26 no.1
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• pp.77-86
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• 2004

The paper is to estimate the economic value of ecotourism in Anmyeondo tidal wetlands using a double-bounded dichotomous choice (DBDC) model of the Contingent Valuation Method (CVM). For the reliability and the validity of CVM a survey was conducted for 511 visitors by personal interview method in Anmyeondo during August 2000, and respondents were asked for maximum Willingness-To-Pay (WTP) to buy a ticket fer the tidal flat's ecotourism. Overall, respondents answered that they would be willing to pay 55,879 won for a ticket under the study. All equations and results estimated are statistically significant at the 1% or 5% level. For the aggregation of WTP estimates, the sample values are extended to the total annual number of visitors in Anmyeondo area during 1998. A conservative estimate, which considers the calibration factor (0.5) recommended by NOAA (1994) and a positive response rate (83.17%), is 73 billion won.

• Journal of Communications and Networks
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• v.3 no.4
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• pp.324-333
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• 2001

The Differentiated Services (Diffserv) framework has been proposed by the IETF as a simple service structure that can provide different Quality of Service (QoS) to different classes of packets in IP networks. IP packets are classified into one of a limited number of service classes, and are marked in the packet header for easy classification and differentiated treatments when transferred within a Diffserv domain. The Diffserv framework defines simple and efficient QoS differentiation mechanisms for the Internet. However, the original Diffserv concept does not provide a complete QoS management framework. Since traffic flows in IP networks are unidirectional from one network point to the other and routing paths and traffic demand get dynamically altered, it is important to monitor end-to-end traffic status, as well as traffic status in a single node. This paper suggests a distributed QoS monitoring method that collects the statistical data of each service class in every Diffserv router and calculates edge-to-edge QoS of the aggregated IP flows by combining routing topology and traffic status. A format modeling of edge-to-edge Diffserv flows and algorithms for aggregating edge-to-edge QoS is presented. Also an SNMP-based QoS management prototype system for Diffserv networks is presented, which validates our QoS management framework and demonstrates useful service management functionality.

• Elastomers and Composites
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• v.52 no.1
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• pp.27-34
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• 2017

In this experiment, blends of ethylene vinyl acetate rubber (EVM) with a vinyl acetate (VA) content greater than 40 wt% and ethylene propylene rubber (EPM) were prepared by mechanical mixing; a number of parameters of the blends, including oil resistance, morphological and dynamic mechanical properties and flame retardancy, were subsequently measured. In the $100^{\circ}C$ oil resistance test, both the ammonium polyphosphate/dipentaerythritol/expandable graphite (APP/DPER/EG) and aluminum hydroxide (ATH) flame retardant systems showed an increase in volume change with increasing EPM content. For the ATH system, the dispersion shape was coarse and aggregation was observed. The results of a dynamic mechanical test showed slightly higher E' and E'' for the APP/DPER/EG flame retardant system when compared to the single ATH system. For both the APP/DPER/EG and ATH systems, the limited oxygen index (LOI) tests performed at increasing content of EPM showed a LOI value higher than 30, indicating excellent flame resistance.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.8 no.7
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• pp.2302-2324
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• 2014

Cluster-based wireless sensor network (WSN) can significantly reduce the energy consumption by data aggregation and has been widely used in WSN applications. However, due to the intrinsic many-to-one traffic pattern in WSN, the network lifetime is generally deteriorated by the unbalanced energy consumption in a cluster-based WSN. Therefore, energy efficiency and network lifetime improvement are two crucial and challenging issues in cluster-based WSNs. In this paper, we propose a Non-Uniform Node Distribution (NUND) scheme to improve the energy efficiency and network lifetime in cluster-based WSNs. Specifically, we first propose an analytic model to analyze the energy consumption and the network lifetime of the cluster-based WSNs. Based on the analysis results, we propose a node distribution algorithm to maximize the network lifetime with a fixed number of sensor nodes in cluster-based WSNs. Extensive simulations demonstrate that the theoretical analysis results determined by the proposed analytic model are consistent with the simulation results, and the NUND can significantly improve the energy efficiency and network lifetime.