• 제목/요약/키워드: Aggregated risk assessment

검색결과 5건 처리시간 0.019초

카드뮴과 납의 다경로 노출량 추정 및 통합 위해성 평가 (Estimation of Multi-Route Exposure and Aggregated Risk Assessment for Cadmium and Lead)

  • 유창우;권훈정
    • 한국식품위생안전성학회지
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    • 제35권6호
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    • pp.587-601
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    • 2020
  • 국내외적으로 유해물질의 통합 노출에 대한 관심은 높아지고 있다. 이러한 흐름에 따라 다양한 경로를 통해 노출될 수 있는 중금속에 대한 통합 노출 연구가 필요하다. 카드뮴과 납은 각각 신장 독성과 인지 장애 등 다양한 독성을 나타낼 수 있으며 또한 발암 물질로 알려져있다. 따라서 본 연구에서는 카드뮴과 납의 노출량 추정 및 통합 위해성 평가를 진행하였다. 2016, 2017년의 7기 국민건강영양조사에 참여한 10,733명의 식품, 물, 흡연과 간접흡연, 호흡, 화장품, 여성용 위생용품을 통한 중금속 노출 추정량을 계산하였다. 결과적으로 카드뮴과 납 모두 식품을 통한 노출이 제일 높게 나타났다. 이외에도 흡연은 카드뮴의 주요한 노출원이었으며, 납은 화장품을 통해 높은 농도로 노출되었다. 통합 위해평가에서도 식품이 가장 큰 영향을 미쳤다. 지역적 특성의 차이는 노출 추정량의 차이를 보이지 못하였으나, 연령 별, 성별 간 노출 추정량은 큰 차이를 보였다. 특히, 월경 중인 성인 여성의 경우 카드뮴, 월경 중이지 않은 여성은 납의 노출 추정량이 더 높으며 신체 대사를 고려하였을 때, 그 위험성이 더 클 수 있음을 암시하였다. 결론적으로 노출량 추정 및 통합 위해평가 모두 식품이 주요 노출원이었다. 다만, 잠재적 위험을 방지하기 위해 다른 경로에 대한 노출량 추정 및 위해평가가 요구된다.

Development of a nanoparticle multi-generator for assessment of inhalation hazard

  • Lee, Sung-Bae;Han, Jeong-Hee;Kim, Tae-Hyun;Cha, Hyo-Geun;Lim, Cheal-Hong
    • 분석과학
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    • 제34권2호
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    • pp.87-98
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    • 2021
  • In this study, we developed the nanoparticle multi-generator by 3D printer fusion deposition modeling (FDM) method that can reliably generate and deliver nanoparticles at a constant concentration for inhalation risk assessment. A white ABS filament was used as the test material, and SMPS was used for concentration analysis such as particle size and particle distribution. In the case of particle size, the particle size was divided by 100 nm or less and 100 to 1,000 nm, and the number of particles concentration, mass concentration, median diameter of particles, geometric average particle diameter, etc were measured. The occurrence conditions were the extruder temperature, the extruding speed of the nozzle, and the air flow rate, and experiments were conducted according to the change of conditions including the manufacturer's standard conditions. In addition, the utility of inhalation risk assessment was reviewed through a stability maintenance experiment for 6 h. As a result of the experiment, the size of the nanoparticles increased as the discharger temperature increased, as the discharge speed of the nozzle increased, and as the air flow rate decreased. Also, a constant pattern was shown according to the conditions. Even when particles were generated for a long time (6 h), the concentration was kept constant without significant deviation. The distribution of the particles was approximately 80 % for particles of 60 nm to 260 nm, 1.7 % for 1 ㎛ or larger, 0.908 mg/㎥ for the mass concentration, 111 nm for MMAD and 2.10 for GSD. Most of the ABS particles were circular with a size of less than 10 nm, and these circular particles were aggregated to form a cluster of grape with a size of several tens to several hundred nm.

Hurricane vulnerability model for mid/high-rise residential buildings

  • Pita, Gonzalo L.;Pinelli, Jean-Paul;Gurley, Kurt;Weekes, Johann;Cocke, Steve;Hamid, Shahid
    • Wind and Structures
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    • 제23권5호
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    • pp.449-464
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    • 2016
  • Catastrophe models appraise the natural risk of the built-infrastructure simulating the interaction of its exposure and vulnerability with a hazard. Because of unique configurations and reduced number, mid/high-rise buildings present singular challenges to the assessment of their damage vulnerability. This paper presents a novel approach to estimate the vulnerability of mid/high-rise buildings (MHB) which is used in the Florida Public Hurricane Loss Model, a catastrophe model developed for the state of Florida. The MHB vulnerability approach considers the wind pressure hazard exerted over the building's height as well as accompanying rain. The approach assesses separately the damages caused by wind, debris impact, and water intrusion on building models discretized into typical apartment units. Hurricane-induced water intrusion is predicted combining the estimates of impinging rain with breach and pre-existing building defect size estimates. Damage is aggregated apartment-by-apartment and story-by-story, and accounts for vertical water propagation. The approach enables the vulnerability modeling of regular and complex building geometries in the Florida exposure and elsewhere.

Urban Quality of Life Assessment Using Satellite Image and Socioeconomic Data in GIS

  • Jun, Byong-Woon
    • 대한원격탐사학회지
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    • 제22권5호
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    • pp.325-335
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    • 2006
  • This paper evaluates and maps the quality of life in the Atlanta, Georgia metropolitan area in 2000. Three environmental variables from Landsat TM data, four socioeconomic variables from census data, and a hazard-related variable from toxic release inventory (TRI) database were integrated into a geographic information system (GIS) environment for the quality of life assessment. To solve the incompatibility problem in areal units among different data, the four socioeconomic variables aggregated by zonal units were spatially disaggregated into individual pixels. Principal components analysis (PCA) was employed to integrate and transform environmental, socioeconomic, and hazard-related variables into a resultant quality of life score for each pixel. Results indicate that the highest quality of life score was found around Sandy Springs, Roswell, Alphretta, and the northern parts of Fulton County along Georgia 400 whereas the lowest quality of life score was clustered around Smyma of Cobb County, the inner city of Atlanta, and Hartsfield-Jackson International Airport. The results also reveals that normalized difference vegetation index (NDVI) and relative risk from TRI facilities are two versatile indicators of environmental and socioeconomic quality of an urban area in the United States.

A probabilistic framework for drought forecasting using hidden Markov models aggregated with the RCP8.5 projection

  • Chen, Si;Kwon, Hyun-Han;Kim, Tae-Woong
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2016년도 학술발표회
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    • pp.197-197
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    • 2016
  • Forecasting future drought events in a region plays a major role in water management and risk assessment of drought occurrences. The creeping characteristics of drought make it possible to mitigate drought's effects with accurate forecasting models. Drought forecasts are inevitably plagued by uncertainties, making it necessary to derive forecasts in a probabilistic framework. In this study, a new probabilistic scheme is proposed to forecast droughts, in which a discrete-time finite state-space hidden Markov model (HMM) is used aggregated with the Representative Concentration Pathway 8.5 (RCP) precipitation projection (HMM-RCP). The 3-month standardized precipitation index (SPI) is employed to assess the drought severity over the selected five stations in South Kore. A reversible jump Markov chain Monte Carlo algorithm is used for inference on the model parameters which includes several hidden states and the state specific parameters. We perform an RCP precipitation projection transformed SPI (RCP-SPI) weight-corrected post-processing for the HMM-based drought forecasting to derive a probabilistic forecast that considers uncertainties. Results showed that the HMM-RCP forecast mean values, as measured by forecasting skill scores, are much more accurate than those from conventional models and a climatology reference model at various lead times over the study sites. In addition, the probabilistic forecast verification technique, which includes the ranked probability skill score and the relative operating characteristic, is performed on the proposed model to check the performance. It is found that the HMM-RCP provides a probabilistic forecast with satisfactory evaluation for different drought severity categories, even with a long lead time. The overall results indicate that the proposed HMM-RCP shows a powerful skill for probabilistic drought forecasting.

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