• Fashion & Textile Research Journal
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• 제20권6호
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• pp.733-743
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• 2018

This study aimed to investigate whether women's wear brands' sizing systems for pants item are reflecting body size and shape of their target age customers. This study classified 17 women's wear brands into three target age groups (20-30s, 30-40s, and 40-50s) and surveyed their body sizing systems of pants item. Distribution of waist circumference and hip circumference of brands' sizing systems were compared with size distribution of women in the 7th Size Korea data. The sizing systems of brands targeting 20-30s covered 28.3% and those of brands targeting 40-50s covered 27.3%, while those of brands targeting 30-40s covers 46.6%. Regarding the body types, 80% of 20-30s target brands reflected normal type which is the average body type. However, all 40-50s target brands reflected normal type while 57.8% of women aged 40-50s had large waist shape. The 30-40s target brands reflected body types the best among target age groups since the body shape distribution of the brands was similar to that of 30-40 year old woman in Size Korea. For each age group, 6 sizes with 25.2~27.8% coverage rates were proposed. The 70-91, 73-91, 73-94 sizes were overlapped between the 20-30s and the 30-40s groups. The 76-91, 76-94, 79-94 sizes were overlapped between the 30-40s and 40-50s groups. Pants size has been found to increase in waist circumference compared to hip circumference as age increased.

• Journal of the Korean Society of Clothing and Textiles
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• 제42권6호
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• pp.1056-1068
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• 2018

This study investigates whether women's wear brands' sizing systems reflect the body size and shape of their target age customers. This study classified 17 women's wear brands into three target age groups (20-30s, 30-40s, and 40-50s) and surveyed their body sizing systems for jacket items. The distribution of bust circumference and hip circumference of brands' sizing systems were compared with the size distribution of women in the 7th SizeKorea data. The brands targeting 20-30s fully produced five sizes which are the highest coverage rate, but the brands targeting 30-40s produced three sizes, and the brands targeting 40-50s produced one size. Regarding the body types, 60.0% of 20-30s target brands and 42.9% of 30-40s target brands reflected N type which is the average body type of each age group. However, the rest of the brands, including all 40-50s target brands, reflected A type which covered small portions of women. For each age group, 6 sizes with 24.0-29.0% coverage rates were proposed. With regard to the 88-94 size, three age groups overlapped: the 82-91 size was overlapped between the 20-30s and the 30-40s groups along with the 85-91 and 88-91 sizes that overlapped between the 30-40s and 40-50s groups.

• The Korean Journal of Physiology and Pharmacology
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• 제22권2호
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• pp.193-201
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• 2018

Connective tissue growth factor (CTGF) is a novel fibrotic mediator, which is considered to mediate fibrosis through extracellular matrix (ECM) synthesis in diabetic cardiovascular complications. Statins have significant immunomodulatory effects and reduce vascular injury. We therefore examined whether fluvastatin has anti-fibrotic effects in vascular smooth muscle cells (VSMCs) and elucidated its putative transduction signals. We show that advanced glycation end products (AGEs) stimulated CTGF mRNA and protein expression in a time-dependent manner. AGE-induced CTGF expression was mediated via ERK1/2, JNK, and Egr-1 pathways, but not p38; consequently, cell proliferation and migration and ECM accumulation were regulated by CTGF signaling pathway. AGE-stimulated VSMC proliferation, migration, and ECM accumulation were blocked by fluvastatin. However, the inhibitory effect of fluvastatin was restored by administration of CTGF recombinant protein. AGE-induced VSMC proliferation was dependent on cell cycle arrest, thereby increasing G1/G0 phase. Fluvastatin repressed cell cycle regulatory genes cyclin D1 and Cdk4 and augmented cyclin-dependent kinase inhibitors p27 and p21 in AGE-induced VSMCs. Taken together, fluvastatin suppressed AGE-induced VSMC proliferation, migration, and ECM accumulation by targeting CTGF signaling mechanism. These findings might be evidence for CTGF as a potential therapeutic target in diabetic vasculature complication.

• Journal of Fashion Business
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• 제6권1호
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• pp.128-136
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• 2002

This study was initiated to study suitability of the apparel sizing systems that utilized in women's ready-to-wear market. To achieve this, the researchers surveyed 383 women from the ages of 18 through 59. The result of this study are followed. 1) The targeted age of the apparel brand does not always correspond with the purchaser's age. The subjects tend to prefer the brands targeting younger women than their age. The women who prefer the brand targeting younger women than their age were less satisfied with the jacket size available in Korean apparel market. They also took into consideration their body size. 2) The subjects who prefer the brands aimed for younger women were dissatisfied with fit at waist and hips. 3) The result of this study also shows that the more sizes are needed for short and tall women. The subjects pointed out that hips of the pants gave worst fit. 4) KS standard size designation system which listed body measurements bust-hips stature was not well known to the consumers.

• The Journal of the Convergence on Culture Technology
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• 제5권2호
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• pp.189-194
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• 2019

In this research, it is the research which carried out the fact-finding for the preparation of old age targeting middle and middle age. After requesting a questionnaire survey for middle-aged and elderly people, it was carried out by the method of collection. A total of 350 copies were distributed, and there were a lot of questions that were poor in response or lacking. Except for the 39 copies, a total of 311 copies of SPSS 22.0 were tried and frequency analysis, t-test and oneway ANOVA were performed. Targeting middle-aged and elderly people, we grasped the difference in regional characteristics and differences in life of old-aged people. The purpose of this study is as follows. First of all, the difference of life in old age according to the socio-demographic characteristics of middle and middle age, second middle and middle age, socio-demographic, economic, life in old age, living in physical age, or social old age It is the provision of basic materials for the preparation of old age by grasping the difference of life.

• The Research Journal of the Costume Culture
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• 제25권3호
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• pp.285-300
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• 2017

This study analyzes the images of models in womenswear advertisements targeting women in their fifties. The goals of this study are: 1) to investigate beauty ideals for middle-aged women by analyzing models' look age, chronological age, wrinkles, gray hair, hair length, body type, and race; and 2) to explore how ageing is dealt with in advertisements by analyzing the range of bodies shown in advertisements, the color mode of photographs, and the clarity of models' figures in relation to models' look ages. A total of 155 printed advertisements from January 2012 to January 2017 from the brands Daks Ladies, Lebeige, Luciano Choi, PAT, and Zishen were selected for analysis. Womenswear brands targeting middle-aged women reinforce cultural ideals of female beauty that emphasize youth and slenderness. They do this by using thin and slender models, who most often appear to be in their twenties and thirties, and have hair longer than their shoulders. Brands with higher price ranges show a preference for Caucasian models, which reveals that a Caucasian identity is associated with sophistication. In addition, the bodies of models who appear to be in their forties and fifties were concealed by framing photographs mostly above the knees. Older models' features were also obscured via the use of black and white photography, strong lighting and contrast, and digital editing that blurred the boundaries between figures and their backgrounds. These decisions for how to represent models could result in negative self-esteem and a denial of the symptoms of ageing among middle-aged women.

• Fashion & Textile Research Journal
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• 제21권6호
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• pp.821-829
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• 2019

This study investigated the location of grading lines and grading amount for a jacket item by the target age groups (20-30, 30-40, and 40-50) for 17 women's wear brands. This study then utilized 7th SizeKorea data to analyze the increase rate of body size and to suggest the grading deviation distribution ratio of the jackets using regression analysis. The increase in neck girth of the jackets targeting aged 30-40s did not reflect the human body change rate. The shoulder length increased by 4.6%-8.1% with the bust girth increase; however, the brands produced longer shoulder length reflecting 20-35% of the bust girth increase. The armhole girth was 54.9% - 59.7% of bust circumstance increase rate. However, the 20-30 target age group brands distributed 80% of bust girth to armhole girth and the 30-40 and the 40-50 target age group brands distributed 50% of the bust girth to armhole. In particular, the 20-30 target age group brands were found to produce a large margin around the armhole. When it came to length items, the brands targeting 20-30s and the 40-50s reflected deviation distribution rate of length from underarm to waist and length from waist to hip in comparison with the overall jacket length deviation. The 30-40 target age group brands, 8 out of 20 brands distributed the jacket length deviation in the length from the back of neck to the underarm; consequently, only 22% percent should be distributed in this part.

• Journal of the Korean Home Economics Association
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• 제31권3호
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• pp.175-186
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• 1993

The present study was designed to find out the construction conditions of tight skirt for sale in relation to its brand, target age and length. The 15 tight skirts each from 3 brand groups(designer character, national and minor brand) of 2 target age groups(youth and middle age) and the 15 tight skirts each from 3 skirt length groups(mini, natural line and maxi) of only the minor brand-a total of the 120 tight skirts on the market-were measured. The data were analyzed with use of SAS package. The statistics were based on frequency, percentage, average, standard deviation, one-way ANOVA, two-way ANOVA, Pearson's correlation and linear regression analysis. The main results were as follows. 1. There were significant differences in the construction conditions of tight skirt according to its brand and target age. There was a significant difference particurarly in the difference between hip girth and hem girth according to brand target age. The difference between hip girth and hem girth of designer's character brand skirt was larger than that of national brand & minor brand skirt, and that of skirt targeting the youth was larger than that of skirt targeting the middle aged. 2. There were significant difference particurarly in the differences in the construction conditions of tight skirt according to its length. There was a significant difference particurarly in the difference between hip girth and he girth according to skirt length, and that of maxi skirt was larger than that of mini & natural line skirt. There was a good correlation between skirt length and slit length and between skirt length and skirt length above the slit. The longer the skirt length was, the longer the slit length and the skirt length above the slit were.

• Neonatal Medicine
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• 제28권3호
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• pp.116-123
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• 2021

Purpose: The aim of this study was to estimate the effect of targeting risk factors for the control of central line-associated bloodstream infection (CLABSI) among high-risk infants in a tertiary neonatal intensive care unit (NICU). Methods: Infants admitted to the NICU and diagnosed with CLABSI from January to December 2013 were eligible for inclusion to the study. The CLABSI group (n=47) was matched in a 1:2 ratio to the control group (n=94) based on gestational age, birth weight, and Score for Neonatal Acute Physiology-II. Risk factors for CLABSI were identified using the Cox proportional hazard model, and analysis of the effect of these risk factors targeting infection control was performed. Results: The risk factors associated with CLABSI were prolonged central line dwell days (adjusted hazard ratio [HR], 1.028; 95% confidence interval [CI], 1.011 to 1.045; P=0.001), use of a silicone catheter (adjusted HR, 5.895; 95% CI, 1.893 to 18.355; P=0.002), surgical treatment (adjusted HR, 3.793; 95% CI, 1.467 to 9.805; P=0.006), and less probiotic supplementation (adjusted HR, 0.254; 95% CI, 0.068 to 0.949; P=0.042). By targeting these risk factors with a quality improvement initiative, the mean CLABSI incidence rate per 1,000 catheter-days decreased from 6.6 to 3.1 (P=0.004). Conclusion: Targeting risk factors for infection control significantly reduced the rate of CLABSI among high-risk infants in the NICU.

• Molecules and Cells
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• 제42권12호
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• pp.821-827
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• 2019

Aging is the most important single risk factor for many chronic diseases such as cancer, metabolic syndrome, and neurodegenerative disorders. Targeting aging itself might, therefore, be a better strategy than targeting each chronic disease individually for enhancing human health. Although much should be achieved for completely understanding the biological basis of aging, cellular senescence is now believed to mainly contribute to organismal aging via two independent, yet not mutually exclusive mechanisms: on the one hand, senescence of stem cells leads to exhaustion of stem cells and thus decreases tissue regeneration. On the other hand, senescent cells secrete many proinflammatory cytokines, chemokines, growth factors, and proteases, collectively termed as the senescence-associated secretory phenotype (SASP), which causes chronic inflammation and tissue dysfunction. Much effort has been recently made to therapeutically target detrimental effects of cellular senescence including selectively eliminating senescent cells (senolytics) and modulating a proinflammatory senescent secretome (senostatics). Here, we discuss current progress and limitations in understanding molecular mechanisms of senolytics and senostatics and therapeutic strategies for applying them. Furthermore, we propose how these novel interventions for aging treatment could be improved, based on lessons learned from cancer treatment.