• Title/Summary/Keyword: Age correlation

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Determination of Phthalate Metabolites in Korean Children's Urine by High Performance Liquid Chromatography with Triple Quadrupole Tandem Mass Spectrometry (LC/MS/MS를 이용한 어린이 소변 중 프탈레이트 대사산물 분석)

  • Kho, Young-Lim;Jeong, Jee-Yeon;Choi, Kyung-Ho;Kim, Pan-Gyi
    • Journal of Environmental Health Sciences
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    • v.34 no.4
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    • pp.271-278
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    • 2008
  • Dialkylated phthalates have been commonly used as plasticizers and a variety of applications. Phthalate diesters have been shown to be developmental and reproductive toxicants. It is very difficult to exactly estimate the dose of dialkylated phthalates taken up by the general population because of environmental contamination. Urinary metabolites of phthalates enabled to estimate internal exposure. The objective of this study was quantitative determination of phthalate metabolites by LC/MS/MS with on-line cleanup method to analyze phthalate metabolites in Korean children's urine. We employed LC/MS/MS with on-line enrichment and column-switching techniques for this biological monitoring. Metabolites determined were 4 primary metabolites; MEHP, MnBP, MiBP, MEP and 2 secondary metabolites of DEHP; 5-OH-MEHP), 5-oxo-MEHP. We analyzed children's urine from 30 boys and 30 girls. The method detection limit of phthalate metabolites were 0.03 ng/mL for MEP, 1.05 ng/mL for MBP, 0.22 ng/mL for MEHP, 0.15 ng/mL for 5-OHMEHP and 0.16 ng/mL for 5-oxo-MEHP, respectively. Switching Column LC/MS/MS was proven to be a useful tool to determine metabolites of phthalate diesters in human urine. The correlation among phthalate metabolites was very high and statistically significant, except MEP. The children's age (months) was negatively correlated to the concentration of phthalate metabolites. The geometric mean concentration of phthalate metabolites (mg/g creatinine) in children's urine were 25.5 for MEP, 130.3 for MnBP, 56.8 for MiBP, 19.5 for MEHP, 85.6 for 5-OH-MEHP and 83.1 for 5-oxo-MEHP, respectively. Levels of estimated daily intake of parent phthalate compounds (${\mu}g$/kg bw/day) were 0.8 for DEP, 5.0 for DnBP, 1.9 for DiBP and $8.9{\sim}14.2$ for DEHP, respectively. Estimated daily intake for DEP and DiBP were lower than those of other studies but the value for DEHP was higher than that of other study.

The influences of spousal support and work-family spillover on work-life balance in dual-earner couples with children: Testing actor and partner effects (맞벌이부부의 배우자 지지, 직장 지지 및 일-가족 전이가 일-생활 균형에 미치는 자기효과와 상대방효과)

  • Jeong, Seo-Leen;Jang, Yoon-Ok
    • Journal of Family Resource Management and Policy Review
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    • v.21 no.3
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    • pp.97-119
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    • 2017
  • The purpose of this study was to find out the actor effect and the partner effect in relation to spousal support, job support, work-family spillover, and work-life balance in dual-earner couples. The subjects of this study were 176 dual-earner couple, whose youngest children are under the age of 16 and who work over 15 hours each week. The research tool was a questionnaires. Factor analysis, Cronbach's ${\alpha}$, correlation analysis, and APIM were performed for the data analysis. The main results of this study as follows. First, for both wives and husbands, perceived spousal support had a positive actor effect on work-life balance. However, perceived husband's spouse support for wife's support had positive partner effect on the wife's work-life balance, the wife's perceived spousal support for her husband' did not have a partner actor effect on the husband's work-life balance. Second, for both wives and husbands, job support had a positive actor effect on work-life balance. In addition, the wife's job support had a positive partner effect on the husband's work-life balance, however, the husband's job support did not have a partner actor effect on the wife's work-life balance. Third, for both wives and husbands, work-family conflict had a negative actor effect on work-life balance. In addition, the wife's work-family conflict had a negative partner effect on the husband's work-life balance, however, the husband's work-family conflict did not have a partner actor effect on the wife's work-life balance. Fourth, for both wives and husbands, work-family enrichment had a positive actor effect on work-life balance. In addition, the husband's work-family enrichment had a positive partner effect on the wife's work-life balance, however, the wife's work-family enrichment did not have a partner actor effect on the husband's work-life balance.

Evaluation of Patients with Rheumatoid Arthritis by Tc-99m MIBI Imaging (류마티스 관절염환자에서 Tc-99m MIBI 영상의 유용성 평가)

  • Cho, Ihn-Ho;Chun, Kyung-Ah;Hong, Young-Hoon;Lee, Choong-Ki;Ha, Jeung-Hee
    • The Korean Journal of Nuclear Medicine
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    • v.38 no.6
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    • pp.506-510
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    • 2004
  • Purpose: We investigated whether Tc-99m MIBI imaging is useful to predict the response of drug treatment in patients with rheumatoid arthritis. Materials and Methods: 24 patients (15 women and 9 men, age $49{\pm}12$ year) rheumatoid arthritis and treated with disease modifying antirheumatic drugs (DMARDs) were included in this study. Erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) were measured, and Tc-99m MIBI scan was obtained before drug treatment. Quantitative analysis of uptake in diseased joints was performed and expressed as joint-to background ratio (J/B) and percent retention (%R) of Tc-99m MIBI. Clinical symptoms were evaluated and graded from 0 (no) to 3 (severe) regarding to presence of tenderness and swelling. Results: J/B of the diseased joints were significantly correlated with ESR and CRP (p<0.05). A highly significant correlation was found between the improvement of clinical symptoms and %R of Tc-99m MIBI (p<0.05). Conclusion: The results demonstrate that Tc-99m MIBI scan may be used to predict the therapeutic response in patients with rheumatoid arthritis.

The Effects of Stress Management and Family Cohesion on Middle-aged Women's Happiness Utilizing the SPSS Program - Focusing on middle-aged women living in Cities K and Y - (SPSS 프로그램을 이용한 중년여성의 스트레스 대처, 가족응집력이 행복감에 미치는 영향 - K시와 Y시에 거주하는 중년여성을 중심으로 -)

  • Shin, So-Jeong;Ko, Jae-Ug
    • The Journal of Korea Institute of Information, Electronics, and Communication Technology
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    • v.11 no.2
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    • pp.137-143
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    • 2018
  • This research aims to analyze the effects of stress management and family cohesion on middle-aged women. Research subjects were 322 middle-aged women living in cities K and Y ranging between 40-60 years of age. A frequency analysis, reliability analysis, and hierarchical regression analysis were carried out utilizing the SPSS 18.0 statistics program. Firstly, results showed that the most frequently shown subjects were between 40-49 years old (59.3%), married (82.7%, 267), high school graduates or less (63.2%, 204), and practiced religion (77.6%, 250). Secondly, stress management, family cohesion, and happiness were the most frequent answers in this order. Thirdly, stress management, family cohesion, and happiness all showed to have a positive correlation. Fourthly, family cohesion had no effect on happiness. Meanwhile, stress management had the biggest effect on happiness with an explanation rate of 28.2%. The implications of this research are expected to be used as base line data for future social welfare programs for the improvement of middle-aged women's happiness.

Pruritus in Burn Survivors (화상환자의 소양증 특성 조사)

  • Kim, Kyung Ja;Won, Mi Hwa
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.1
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    • pp.45-53
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    • 2016
  • This study examined pruritus to provide the data based on burn patient pruritus. A self-report questionnaire survey was conducted among ninety five burn survivors, who were over 18 years of age with admission periods longer than two weeks. The results indicated that the average burn range was $18.95{\pm}17.10%$, severity was $48.83{\pm}23.96$, and distress was $46.42{\pm}25.80$. A significant difference in pruritus consequences was observed according to frequency. The patients consistently experienced pruritus, even if it happened less often, difficulty in falling asleep (F=4.817, p=.004), poor mood (F= 5.955, p=.015)), and loss of concentration (F=6.483, p<.000). A significant difference in the pruritus consequences according to duration was observed, lasting for 30 minutes for all groups, more than the population and less than 30 minutes, difficulty in falling asleep (F=7.452, p<.000), poor mood (F=3.655, p<.015), and loss of concentration (F=12.564, p<.000). The frequency, duration (r=.29, p=.004), severity (r=.45, p<.000), distress (r=.44, p<.000), and consequences of pruritus in burn patients (r=.29, p=.004) showed a positive correlation. The results of this study could be used as a base material for the care of burn patients experiencing pruritus.

The Differences in Preference for Vegetables among Primary School to University Students in Gyeongbuk Area (경북지역 초.중.고.대학생의 채소류 기호도와 섭취빈도 비교)

  • Lee, Yun Kyeong;Kim, Youngnam
    • Korean Journal of Community Nutrition
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    • v.19 no.5
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    • pp.415-424
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    • 2014
  • Objectives: Vegetables are the most left over side dishes in school lunch programs. This study intended to analyze the differences in preference for vegetables among the students of different age groups in order to determine potential ways of increasing vegetable consumption in this study group. Methods: A total of 308 primary to university students in Gyeongbuk area were recruited and a questionnaire-based survey was conducted. The preference score (7-Likert scale: very much dislike (1)~so-so (4)~like very much (7)) and intake frequency (5-Likert scale) of 48 kinds of vegetables in 4 vegetable groups, such as vegetable (fruit-, root-, leaf-, and stalk-vegetable), seaweeds, mushrooms, and kimchi were investigated, and data were analyzed by SPSS WIN (ver 12.0). Results: The preference scores of vegetables except for seaweeds were significantly different among school groups, university was the highest, followed by high school. Primary and middle school students showed the lowest preference score, especially for leaf- and stalk- vegetables. The preference score for seaweeds was the highest of 5.28, followed by kimchi of 4.99. With regard to kimchis, the preference score was the highest in university', followed by high school, middle school, and primary school' was the lowest. The number of vegetables with < 4.0 preference score was the highest in primary school of 16, 15 in middle school, 11 in high school, and 7, the lowest in university. The vegetable with preference score of < 4.0 in all 4 school groups were mallow, chard, bud, radish leaf, mugwort, butterbur and sweet potato stalk. With regard to the intake frequency of vegetables, kimchis, an indispensable part of the Korean diet, was the highest of 2 times/day, followed by cooked vegetables of 1.5 times/day. The correlation coefficients between preference scores and intake frequencies were statistically significant in all groups of vegetables. As for the coefficient of variation (CV) of preference score, primary school' was the highest and university' was the lowest. The number of vegetables with high CV and high inexperience were highest in primary school students. Conclusions: Providing more opportunities for consuming a variety of vegetables, such as leaf- and stalk-vegetable, it may be possible to increase vegetable consumption, especially for the primary school students.

Trace Element Analysis and Source Assessment of Parking Lot Dust in Large Shopping Mall (대형유통업소주차장의 축적먼지 중 미량원소성분 분석과 오염원 평가)

  • Song, Hee-Bong;Ahn, Jeong-Eem;Jung, Yeoun-Wook;Yoon, Ho-Suk;Keum, Jong-Lok;Do, Hwa-Seok;Kim, Sun-Suk;Kim, Jong-Woo
    • Journal of Korean Society of Environmental Engineers
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    • v.34 no.3
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    • pp.168-176
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    • 2012
  • A total of 48 dust samples were collected from large shopping mall parking lots in Daegu metropolitan city in March 2011. Samples were sieved through a 100 ${\mu}m$ mesh and the concentration of 14 elements have been determined using by ICP after acid extraction. Results showed that Ca, Fe, K, Mg, Mn, Na and V were affected by natural sources while Cd, Cr, Cu, Ni, Pb and Zn were affected by anthropogenic sources. The measured values were remarkably higher in components from natural sources than in components from anthropogenic sources. Anthropogenic trace element concentrations of ground roof dust were higher than those of ground and underground indoor dust. A large percentage of trace elements came from natural sources rather than anthropogenic sources. The percentage composition of chemicals of ground roof dust were higher than those of ground and underground indoor dust. This study showed that investigated parking lots were rarely contaminated with hazardous heavy metals. The heavy metal pollution of ground roof were higher than those of ground and underground indoors. The correlation analysis among trace elements suggest that components in ground roof were more highly correlated than those in ground and underground indoor. Also anthropogenic trace element levels were well correlated with parking lot age and parking density.

The Relationships among Gait Parameters and Senior Fitness Variables in Korean Elderly People (노인 체력 측정 결과와 보행 특성의 관계)

  • Joo, Ji-Yong;Hwang, Yeon-hee;Kim, Young-Kwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.1
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    • pp.208-215
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    • 2020
  • This study investigated the relationship among gait variables and physical fitness variables for Korean elderly people. Two hundred elderly people aged 65 to 85, (100 men and 100 women) participated in this study. They performed senior fitness test consisting of 6 tests, 3 additional physical tests (vertical jump, one leg stand, and grip force), body composition measures, and gait test. The gait test used shoes having an inertia measurement device in the outer-soles. The results indicated that the stride length, 6-min walking, lean body mass, and dumbbell curls were significantly affected by age (the above 75 group vs. the below 75 group). Among 33 measured parameters, the principal component analysis (PCA) revealed five PCs such as gait characteristics, physical features, gait variability, and fitness levels. In addition, the correlation analysis showed that the preferred walking speed was significantly, positively associated with stride length and single support time, whereas it was negatively associated with double support time and gait variability.(Ed note: please confirm my modification) In conclusion, sarcopenia should be avoided in elderly people, and resistance exercise is highly recommended to help elderly people maintain their gait ability.

The Relationships between Emotional Labour, Depressive Symptoms and Presenteeism among Counselors in Call Centers (콜센터 상담원들의 감정노동 및 우울과 프리젠티즘과의 관련성)

  • Baek, Jong-Tae;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.4086-4097
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    • 2015
  • This study examined the level of an emotional labour, depressive symptoms, and presenteeism of counselors working in a call center depending on socio-demographic characteristics, health-related factors, and job-related factors. Especially, the main purpose of a survey was to investigate the relevance to an emotional labour, the level of depressive symptoms and presenteeism. The research subjects were 304 counselors working at two call centers in Daejeon, and the survey was conducted from April 1, 2014 to May 31, 2014, using a structured self-administered questionnaire. As a result, the emotional labour, depressive symptoms and presenteeism experienced by the research subjects had a deep relation to many variables like socio-demographic characteristics, health-related factors and job-related factors. Especially, presenteeism showed a meaningful positive correlation with depressive symptoms and emotional labour factors. According to the result of a hierarchical multiple regression analysis, the meaningful variables related to presenteeism were age, the amount of a physical burden, the level of depressive symptoms, the surface action of an emotional labour. Therefore, to lower down the counselors' presenteeism, the development and implement of a mental healthcare program to control not only depressive symptoms and the level of an emotional labour is urgently needed.

The Study on Risk Factor of Metabolic Diseases in Pancreatic Steatosis (췌장지방증에서 대사성질환의 위험 요인에 관한 연구)

  • Cho, Jin-Young;Ye, Soo-Young;Kim, Dong-Hyun
    • Journal of radiological science and technology
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    • v.39 no.1
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    • pp.81-88
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    • 2016
  • The body of the fat tissue increased in obese represented by risk factors such as cardiovascular diseases, diabetes, metabolic disease and dyslipidemia. Such metabolic diseases and the like of the cardiovascular and cerebrovascular disease, hypertension, dyslipidemia, increase in the adipose tissue of the pancreas is known to be a risk factor of these diseases. Study on the diagnosis and treatment of pancreatic cancer was conducted actively, case studies on pancreatic steatosis is not much. In this study, divided into a control group diagnosed with pancreatic steatosis as a result of ultrasonography to evaluation the physical characteristics and serologic tests and blood pressure and arterial stiffness. The control group and the test pancreas steatosis age and waist circumference, body mass index, total cholesterol, HDL cholesterol, LDL cholesterol, and systolic and diastolic blood pressure, fasting blood glucose, arterial elasticity is higher in pancreatic steatosis. And the lower ankle brachial stenosis and HDL-cholesterol were lower than the normal control group, so the pancreatic steatosis harmful to blood vessels.(P <0.05). The difference between the control group and it was confirmed that the pancreatic jibanggun statistically significant. In conclusion, pancreatic steatosis at abdominal ultrasound can predict the risk of metabolic diseases, and there was a correlation with cardiovascular disease.