• Nutrition Research and Practice
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• 제11권2호
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• pp.114-120
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• 2017

BACKGROUND/OBJECTIVES: A pivotal role of oxidative stress has been emphasized in the pathogenesis as well as in the disease progression of Parkinson's disease (PD). We aimed at investigating serum levels of antioxidant vitamins and elucidating whether they could be associated with the pathogenesis and progression of PD. MATERIALS/METHODS: Serum levels of retinol, ${\alpha}$- and ${\gamma}$-tocopherols, ${\alpha}$- and ${\beta}$-carotenes, lutein, lycopene, zeaxanthin and ${\beta}$-cryptoxanthin were measured and compared between 104 patients with idiopathic PD and 52 healthy controls matched for age and gender. In order to examine the relationship between antioxidant vitamins and the disease progression, multiple group comparisons were performed among the early PD (Hoehn and Yahr stage I and II, N = 47), advanced PD (stage III and IV, N = 57) and control groups. Separate correlation analyses were performed between the measured antioxidant vitamins and clinical variables, such as Hoehn and Yahr stage and Unified Parkinson's Disease Rating Scale (UPDRS) motor score. RESULTS: Compared to controls, PD patients had lower levels of ${\alpha}$- and ${\beta}$-carotenes and lycopene. ${\alpha}$-carotene, ${\beta}$-carotene and lycopene levels were significantly reduced in advanced PD patients relative to early PD patients and were negatively correlated with Hoehn and Yahr stage and UPDRS motor score in PD patients. No significant differences were found in serum levels of retinol, ${\alpha}$- and ${\gamma}$-tocopherols, and other carotenoids between PD patients and controls. No significant correlations were found between these vitamin levels and clinical variables in PD patients. CONCLUSTIONS: We found that serum levels of some carotenoids, ${\alpha}$-carotene, ${\beta}$-carotene and lycopene, were lower in PD patients, and that these carotenoids inversely correlated with clinical variables representing disease progression. Our findings suggest that decreases in serum ${\alpha}$-carotene, ${\beta}$-carotene and lycopene may be associated with the pathogenesis as well as progression of PD.

• 한국치위생학회지
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• 제15권1호
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• pp.81-89
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• 2015

Objectives: The purpose of the study is to investigate the effect of values on major satisfaction in dental hygiene students. Methods: The subjects were 214 dental hygiene students in Seoul and Gyeonggi-do who filled out the self-reported questionnaire after receiving informed consents from January 20 to February 15, 2014. Except incomplete answers, 187 data were analyzed using PASW Statistics 18.0 for Scheffe post hoc test, Pearson correlation coefficient, hierarchical regression analysis, independent sample t-test, and one-way ANOVA. The questionnaire consisted of general characteristics of the subjects and values. General characteristics consisted of gender, age, grade, school record, major choice motivation, and the influencing person to choose the major. The instrument for values was modified from Shin based on MILOV(Multi-Item Measures Of Values) and two professors of dental hygiene verified the validity of the instrument. Instrument for values consisted of 7 questions of values for self-respect, 6 questions of relation oriented values, 5 questions of emotion oriented values, and 5 questions of values for others measured by Likert 5 scale. Cronbach's alpha was 0.769 in the study. The instrument for major satisfaction was modified from Na based on Program Evaluation Survey of Illinois University and two professors of dental hygiene verified the validity of the instrument. Major satisfaction consisted of 7 questions of general satisfaction, 5 questions of consciousness satisfaction, 5 questions of curriculum satisfaction and 3 questions of relation satisfaction measured by Likert 5 scale and Cronbach's alpha was 0.887 in the study. Results: Values of self-respect, relationship orientation and grade had significant influence on general satisfaction, while values of self-respect, relationship orientation and gender had significant influence on consciousness satisfaction. Values of relationship orientation, grade and school record had significant influence on curriculum satisfaction. Grade showed significant influence on relationship satisfaction. Conclusions: Values of self-respect and relationship orientation are the most important factors in dental hygiene students. The guidance for professional career and major satisfaction can be accomplished through the values of self-respect and relationship orientation.

• 지질공학
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• 제26권2호
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• pp.207-221
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• 2016

최근 국내 필댐 및 저수지의 노후화가 급속도로 진행되고 있으며, 이에 따른 제체의 손상이나 붕괴사고가 잇따르고 있다. 그러나 필댐의 핵심적인 차수기능을 담당하는 코어층에 대한 열화와 잠재 위해성 분류에 대한 연구는 거의 미진한 실정이다. 본 연구에서는 노후화가 진행 중인 13개 기존 코어형 필댐에 대해(준공 후 경과년수 9-52년, 댐 높이 22-67 m), 무수보링에 의한 코어층 시추 지반조사와 표준관입시험, 2D 및 3D 전기비저항탐사, 물성·역학시험을 수행하여 공학적 기반의 잠재적 위해성 유형을 국내 최초로 분류, 제시하였다. 중심코어층에 대한 무수보링 시추 지반조사 결과, 코어재 잠재 위해성 유형을 국부적 포화대, 신속한 공내수 유입, 조립질 혼재 코어재, 상대적 저 강성의 네 종류로 분류하였다. 코어형 필댐의 잠재 위해성 유형 중국부적 포화대 유형은 코어존 내 유로의 성장 및 발달에 의한 내적침식의 가능성이 존재하므로 가장 위험한 위해성으로 분류 되었으며, 코어재의 열화 등급에 따라 적절한 차수능 회복을 위한 보수보강이 필요한 것으로 판단되었다. 그 외 세 가지 위해성 유형은 즉각적인 조치보다는 지속적인 모니터링과 정기 검사의 강화가 필요할 것으로 검토되었다. 본 연구대상 댐의 분석 결과, 준공 후 경과년수와 댐 코어재의 열화 양상과는 상관성이 크게 없는 것으로 나타났다. 본 연구 결과는 코어형 필댐의 노후화에 따른 댐의 안전관리와 성능개선에 있어 유용한 자료로 활용 가능할 것으로 판단된다.

• 감성과학
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• 제8권4호
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• pp.415-422
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• 2005

본 연구에서는 행동활성화체계(Behavioral Activation System : BAS)와 행동억제 체계(Behavioral Inhibition System : BIS)의 성향이 청년층과 노인층의 뇌파 특성에 차이를 보이는지를 조사하였다. 실험은 19명의 청년층과 31명의 노인층을 대상으로 하여 이루어졌고, 안정 상태의 양측 전전두엽 뇌파를 측정하였다. 분석은 비선형 지수 중 하나인 1/f스케일링 지수를 사용하였다. 그 결과, BAS 성향에서 1/f스케일 지수가 유의한 차이를 보였다. 즉, 좌측 전전두엽(Fpl)에서는 청년층의 1/f스케일 지수가 노인층의 1/f스케일 지수보다 통계적으로 유의하게 높은 값을 보였고, 우측 전전두엽(Fp2)에서도 청년층이 노인층에 비해 높은 1/f스케일 지수를 나타내는 경향을 보였다. 1/f 스케일 지수가 클수록 복잡도는 감소하고, 반면 확률분포에 관련된 정보의 양은 증가하는 것으로 해석 가능하다. 본 연구를 통해, 주관적 평가 결과로서 행동 활성화체계가 강한 성향을 가진 경우, 노인층은 청년층에 비해 양측 전전두엽의 복잡도가 높은 상태임을 알 수 있다 본 연구의 결과는 BAS성향과 연령 사이의 연관성에 대한 가능성을 시사한다.

• Clinics in Shoulder and Elbow
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• 제2권2호
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• pp.126-132
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• 1999

Purpose : To evaluate the functional and radiographic outcome of the modified Bosworth method in the surgical treatment of acute type V acromioclavicular joint dislocation. Materials and Methods: From June 1995 to May 1998, 20 patients were operated on for acute and complete acromioclavicular dislocation(Rockwood type V). The operative technique includes fixation of the coracoclavicular joint with Bosworth screw or 6.5mm cancellous screw and imbrication of trapezius and deltoid muscles. The average age was 34 years(range, 19 to 51 years). These 20 patients with an average follow-up of 18months, were evaluated clinically using the UCLA scoring system. Additional radiographical assessment was performed with stress radiographs. Results: Excellent or good clinical results were obtained in 95%(19 cases). And the average coracoclavicular interval ratio was decreased from 3.31(2.2-6.0) to 1.13(1-1.4) in stress radiographs. There were 4 cases of hetero­topic calcification postoperatively but there was no correlation with clinical result. Posttraumatic A-C joint arthritis was developed in one case. In that case, the distal clavicular resection was done under the arthroscopic technique. Conclusion: The severe displacement observed with type V injuries is incompatible with normal shoulder function if the shoulder is left in its displaced position. In type V injuries, significant damage to the deltoid and trapezius musculature and overlying fascia occurs, therefore open reduction and good fixation must be obtained with imbrication of trapezius and deltoid muscles. In our type V acute complete acromioclavicular dislocation, the modified Bosworth technique provides excellent results with a low complication rate.

• 대한두경부종양학회지
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• 제10권2호
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• pp.200-205
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• 1994

Proliferating cell nuclear antgen(PCNA) plays an important role in DNA synthesis in nucleoli and is highly conserved non-histone nuclear protein composed of 261 amino acid. and is considered to correlated with the cells proliferative state, because it is synthesized particulary during the proliferative period of late Gland S-phase. Therefore, PCNA index meaningfully increases in the active or proliferative kinetic cells. By the use of recently developed monoclonal antibodies against PCNA, the immunohistochemical staining methods can make possible. These staining methods are the useful and productive one for ascertaining the cell's proliferating abillity. Moreover, immunohistochemical staining method with a antiPCNA antibody has particulrar advantages as follows. By means of these methods, we can stain the tissue that was already fixed in formalin or paraffin wax. We can see with naked eye that which cell is, where is differentiated through a microscope. Lastly, it maintains the whole tissue architecture and makes a search for the correlation. As we have seen above, the immunohistochemical staining methods for PCNA have been studied as an impotant factor that can find the cell proliferative kinetics in malignancy and biologic behavior of tumors. To investigate of the proliferative activity in thyroid nodule, Authors evaluated cell proliferative activity by immunostaing for PNCA in 45 pathologically confirmed solitary thyroid nodule. The results were as follows. 1) The benign nodules were 25 cases(Adenomatous Goiter: 20 cases, Follicular adenoma: 5 cases) and malignant nodules were 20 cases(Papillary Ca : 14 cases, Follicular Ca : 4 cases, Anaplastic Ca : 2 cases). 2) The Most prevalent age groups were 4th decade(11 cases), and the next group was 5th decade. 3) The average PCNA labelling indices were as follows. Adenomatous goiter(I6.9%), Follicular adenoma(37.6%), papillary Ca(26.3%), Follicular Ca(8.8%) and Anaplastic Ca(86.7%). There were no significant differences in benign(20.4) and malignant nodules (28.8%) except anaplastic Ca(p=0.3226). 4) When the average tumor size 2cm in papillary Ca, the PCNA indices were 26.0% (below 2cm) : 26.6% (above 2cm) (p=0.9642). The PCNA incidies were 23.9% (with lymphatic spread) : 28.7% (without lymphatic spread) (p=0.7056). There were no signlficant differences in the above cases. In conclusion, there were no significant differences in cell proliferative activity by staining for PCNA between benign and malignat nodules except anaplastic Ca.

• 가정과삶의질연구
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• 제33권3호
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• pp.15-29
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• 2015

The purpose of this study was to explore ethnic socialization enacted by Japanese marriage migrant women currently raising 7- to 18-year-old children in Korea. To accomplish this goal, we examined the following research questions: (1) What is the level of ethnic socialization enacted by Japanese marriage migrant mothers? (2) Does the level of ethnic socialization vary by demographic and ethnocultural factors? (3) To what extent do demographic and ethnocultural factors influence the enactment of ethnic socialization by Japanese marriage migrant mothers? The sample consisted of 243 Japanese marriage migrant women currently raising 7- to 18-year-old children in Korea. For data analysis, T-test, correlation, ANOVA, and hierarchical regression analyses were used. Also, we performed separate analyses for two subtypes of ethnic socialization in particular, namely cultural socialization and preparation for bias. Ethnocultural factors examined in this study were the level of discrimination experience, Japanese ethnic identity, and husbands' ethnic orientation in childrearing. The main results of this study were as follows. First, results showed that Japanese marriage migrant women enacted moderate levels of cultural socialization and preparation for bias. Second, Japanese marriage migrant women's cultural socialization and preparation for bias were both positively related to the levels of women's discrimination experience and Japanese ethnic identity. Also, the younger the age of the firstborn child, the more preparation for bias these women performed. In addition, women whose Korean husbands wanted to raise their children more biculturally performed more cultural socialization compared to those with Korean husbands who wanted to raise their children as Korean. Third, hierarchical regression analyses revealed that women's discrimination experience and ethnic identity positively predicted both types of ethnic socialization. Also, Korean husband's bicultural orientation towards childrearing predicted a higher level of cultural socialization by Japanese marriage migrant women. Results of this study provide basic information about ethnic socialization among multicultural families in Korea, which can be useful for promoting positive self-identity among multicultural children. Furthermore, the results suggest that husbands' support and cooperation in ethnic socialization can be crucial for marriage migrant women to socialize their children utilizing their cultural and experiential resources.

• 대한가정학회지
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• 제43권5호
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• pp.183-198
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• 2005

The purpose of this study was to discuss the relationship between Korean people's normative sense of the traditional filial piety and their affiliation with relatives. For this purpose, the researcher reviewed ethics books during the Chosun dynasty such as Naehoon Women's Ethics), Dongmongsonsup (Children's Cardinal Moral Principles) ,Kyokmongyokyol (Juvenile's Learning) and Gyuenyoso (Instructions for Daughters of Marriageable Age), Based on this review a questionnaire was designed. For the survey,566 returned questionnaires from married people between their 20's and 70's living in Seoul and Wonju Si were sampled The collected data were analyzed using the SAS program for means and SDs of each area in order to examine the overall tendency, and were subject to one-way ANOVA to determine the relationship between their normative sense of the traditional filial piety and their affiliations with relatives depending on their demographic variables, In addition to this correlation analysis, the data underwent regression analysis to determine the significant factors affecting the subjects' sense of filial piety and their affiliation with relatives. The results of this study can be summarized as follows ; First, the subjects were found to have a normal or higher sense of filial piety in overall terms, which suggests that the Korean morality of filial piety may be positive. In particular, the subjects' sense of filial piety was higher for living parents than for dead ones. Namely, they wanted to give more respect, honor and support to their parents than give a cordial funeral or memorial service to deceased parents. Second, older Koreans were more aware of filial piety, and men were more conscious of filial piety than women. Buddhists or atheists tended to be more faithful to their parents. Generally, those with lower academic background and living with larger families had a higher normative sense of filial piety. On the other hand, those in their 60's and 70's were most affiliated with their relatives, while youth and middle-aged people were less affiliated with their relatives. Men were more affiliated with their relatives than women, and first sons or daughters were more affiliated with their relatives. Besides, those living with larger families were more affiliated with their relatives. Third, the subjects' normative sense of filial piety, particularly for deceased parents, was highly correlated with their affiliation with relatives, and such a normative sense of filial piety was most conspicuous in their funeral rites.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제39권6호
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• pp.274-282
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• 2013

Objectives: The posterior maxillary region often provides a limited bone volume for dental implants. Maxillary sinus elevation via inserting a bone graft through a window opened in the lateral sinus wall has become the most common surgical procedure for increasing the alveolar bone height in place of dental implants in the posterior maxillary region. The purpose of this article is to assess the change of bone volume and the clinical effects of dental implant placement in sites with maxillary sinus floor elevation and autogenous bone graft through the lateral window approach. Materials and Methods: In this article, the analysis data were collected from 64 dental implants that were placed in 24 patients with 29 lacks of the bone volume posterior maxillary region from June 2004 to April 2011, at the Department of Oral and Maxillofacial Surgery, Inha University Hospital. Panoramic views were taken before the surgery, after the surgery, 6 months after the surgery, and at the time of the final follow-up. The influence of the factors on the grafted bone material resorption rate was evaluated according to the patient characteristics (age and gender), graft material, implant installation stage, implant size, implant placement region, local infection, surgical complication, and residual alveolar bone height. Results: The bone graft resorption rate of male patients at the final follow-up was significantly higher than the rate of female patients. The single autogenous bone-grafted site was significantly more resorbed than the autogenous bone combined with the Bio-Oss grafted site. The implant installation stage and residual alveolar height showed a significant correlation with the resorption rate of maxillary sinus bone graft material. The success rate and survival rate of the implant were 92.2% and 100%, respectively. Conclusion: Maxillary sinus elevation procedure with autogenous bone graft or autogenous bone in combination with Bio-Oss is a predictable treatment method for implant rehabilitation.

• 대한소아치과학회지
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• 제34권1호
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• pp.130-139
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• 2007

다운증후군 환자의 치아우식증과 구강내 여러 요인들과의 연관성을 평가하고자 9-18세의 다운증후군 환자 25명과 정상인 63명을 대상으로 치아우식경험지수, 치태지수를 조사하고 효소면역분석법을 이용하여 타액의 면역항체 IgA와 뮤탄스 연쇄상구균-특이 IgA농도를 측정하고, Dentocult 키트를 이용하여 뮤탄스 연쇄상구균과 유산간균의 수, 타액의 완충능을 측정하여 두 군의 각 값들을 독립 t-test와 카이제곱 검정을 시행하였다. 다운증후군 환자에서 유치우식경험은 정상인에 비해 유의하게 낮았으나(p<0.001), 영구치우식경험은 유의한 차이를 보이지 않았다. 치태지수와 타액의 IgA의 농도는 두 군간에 차이를 보이지 않았으며, 뮤탄스 연쇄상구균 특이-IgA 농도와 타액 완충능은 다운증후군환자에서 낮았다(p<0.05). 뮤탄스 연쇄상구균 수와 유산간균 수는 두 군간에 유의한 차이는 없었다. 9-11세 군에서 뮤탄스 연쇄상구균의 수는 다운증후군 환자에서 정상인보다 낮았으며(p<0.001), 뮤탄스 연쇄상구균 특이-IgA는 다운증후군 환자에서 유의하게 낮았다(p<0.05). 유치의 치아우식경험치면지수는 완충능, 뮤탄스 연쇄상구균의 수와 유의한 상관관계를 보였다.