• Title/Summary/Keyword: Age correlation

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Effects of Vitamin E Supplementation on Renal Glycosylation Products in Diabetic KK Mice (당뇨 KK마우스에서 비타민 E 보강식이가 신장 당화단백질 생성에 미치는 영향)

  • 안현숙;박성연;김해리
    • Journal of Nutrition and Health
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    • v.31 no.6
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    • pp.1024-1030
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    • 1998
  • We investigated the effects of vitamin E supplementation on protein glycosylation in early and end stage product, and light microscopic studies were done on the renal glomeruli of KK-mice of various ages and various duration of diabetes. Weaned KK-mice were fed high fat diets containing 20% corn oil(wt/wt), and sacrificed at 4,6, and 9 months of age. The high vitamin E diet was a high fit diet supplemented with an excess amount of d1-$\alpha$-tocopheryl acetate (2080IU/kg diet). We measured Hemoglobin $A_{IC}$ (Hb $A_{IC}$) as a glycosylation early product, and renal collagen-linked fluorescence as a glycosylation end product. In the diabetic group, levels of Hb $A_{IC}$ were increased within 2 months after onset of diabetes and remained at a constant level for the duration of experiment. 5 months after onset of diabetes, renal collagen linked fluorescence(CLF) was markedly increased. A quantative, morphologically demonstratable, progressive thickening of the basement membrane and calcification occured in the diabetic KK-mice. There is a statiscally positive correlation between CLF and histologic grade of diabetic nephropathy. Hepatic vitamin E levels correlated with those of Hb $A_{IC}$, renal CLF, and renal calcification. Treatment with vitamin I did not modify the level of blood glucose. However, we observered a significant lowering of CLF and Hb $A_{IC}$ in diabetic mice. Supplementation of vitamin E was found to delay the progression of diabetic nephropathy. (forean J Nutrition 31(6) : 1024-1030, 1998)0, 1998)

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A Study on the Correlation between Spatial Distance and Cognitive Intensity of High-rise Buildings - Focusing on High-rise Buildings of More than 30 Stories in Seoul - (초고층 랜드마크의 공간적 거리 및 인지강도와의 상관성 분석 - 서울시 30층 이상 고층건물을 대상으로 -)

  • Byeon, Jae-Sang;Im, Seung-Bin;Joo, Shin-Ha
    • Journal of the Korean Institute of Landscape Architecture
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    • v.35 no.4
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    • pp.90-104
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    • 2007
  • Landmarks like high-rise building are one of the important elements for the enhancement of city identity and provides the hierarchy of city streets, playing a central and symbolic role in cities. Research on physical attribute of landmarks, such as height, distance, location and shape, which are suitable for a city scale, can help a city create a distinct image and maintain comprehensible structure. To achieve this purpose, it is necessary to understand the spatial and cognitive characteristics of a landmark for the establishment and management of it. The results of this study can be summarized as follows: 1. The level of representativeness of a landmark increases in proportion to the degree of cognitive intensity on it. The relation between representativeness and cognitive intensity can be explained as the log-function as follows: Log(the number of people who respond "It has representativeness")=$-1.2579+1.5908{\times}$(cognitive intensity); 2. There are a few differences based on the attributes of respondents: while gender has no distinct influence, residential period and age show statistically meaningful influence on cognitive intensity of a vertical landmark Cognitive intensity of an individual landmarks especially, differs according to the class of main users. Because of frequent changes in occupation or employment, respondents consider the distance from a residential area more important than the distance from a working area in evaluating cognitive intensity of landmarks; 3. landmark can be classified into two kinds: a district landmark and an urban landmark A district landmark is closely connected with physical attributes of the landmark itself, such as distance, size and height. An urban landmark is mainly related to cognitive attributes such as the image and identity of a city as a whole. As a result, the landmark analysis data in this research provides spatial order and identity in a city. It is difficult to establish and reinforce the image of a city as a single element ike a landmark. However, withy steady follow-up research, this study could be seen as a systematic and logical model to improve urban landscape and image.

Relationship between Psychosocial Factors, Job Stress Contents, Fatigue Symptoms and Quality of Nursing Services among General Hospital Nurses (종합병원 간호사들의 사회심리적 요인, 직무스트레스 및 피로와 간호서비스의 질과의 관련성)

  • Lee, Myung-Jun;Yoon, Seok-Han;Cho, Young-Chae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.17 no.8
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    • pp.569-581
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    • 2016
  • The purpose of this study was to define the quality of nursing services in relation to a nurse's psychosocial factors (type A behavior pattern, self-esteem, locus of control, and anxiety), job stress, and fatigue. This study targeted 503 nurses currently working at one of six general hospitals in Daejeon city, the data were collected by a self-administered questionnaire, which was surveyed from April 1 to June 30, 2014. According to multivariate logistic regression analysis, the high self-esteem, locus of control, and strong support by supervisor and co-workers decrease the risk of a low career quality. In contrast, high situational fatigue and overall fatigue increase the risk of a low career quality. According to the results of hierarchical multiple regression analysis, the quality of nursing services increased with age, the subjective health condition was satisfying, aptitude corresponded to the jobs, self-esteem was high, anxiety was low, support by co-workers was strong, and the overall fatigue was low. Above results suggest that the quality of nursing services of nurses who work at a general hospital has a strong correlation with the psychosocial factors, job stress, and fatigue.

Influence of Anaerobic Exercise on Fatigue Material and Basic Fitness of Career Wrestlers (무산소성 운동이 경력별 레슬링 선수의 피로물질 및 기초체력에 미치는 영향)

  • Lee, Kyung-Yul;Shin, Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.5514-5521
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    • 2013
  • This study is an experiment to look into recovering process after maximum anaerobic exercise of career wrestlers and their basic fitness. First, group time results in anaerobic power test did not show meaningful differences between groups in PP, MP, LP field. Second, blood glucose showed meaningful difference in 5-year wrestlers group according to time-wise result (p<.001). Third, time-wise results in blood lactic acid concentration showed meaningful difference all in 5-year, 10-year and 15-year career wrestlers group (p<.001). Fourth, side step and general reaction did not show meaningful differences in all the 3 groups. In conclusion, increase or decrease was seen from and also significant differences were seen from the change of anaerobic power, glucose, lactic acid, concentration, basic physical strength reaction which have influence over athletic performance of players after anaerobic exercise. It was found that 5-year career players group was good at variables of power test and glucose. Reason why recovery capability in connection with degree of fatigue was poor in 15-year career players group seemed to have correlation between career and age.

An Evaluation of Habitual Head Posture in Phoria (사위에서 습관적인 머리위치의 평가)

  • Ha, Eun-Mi;Son, Jeong-Sik;Yu, Dong-Sik
    • Journal of Korean Ophthalmic Optics Society
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    • v.18 no.3
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    • pp.341-346
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    • 2013
  • Purpose: The purpose of this study was to evaluate whether a relationship exists between head posture and phoria, and usefulness in examining habitual head posture. Methods: Twenty two subjects (20 males and 2 females, mean age $23.6{\pm}2.7$ years) with abnormal phoria from participants randomized were enrolled in this study. For all subjects, testing included case history, cover test, refraction, phoria and vergence test. Habitual head posture (head posture, head tilt and face turn) was measured by Impression IST, and observed by examiners. Results: The abnormal head posture was revealed in some subjects with abnormal phoria. Spearman' correlation ($\rho$=0.524, p=0.045) showed significant correction between face turn and phoria at distance in 15 subjects with prism prescription. No significant relationship between head posture and phoria was found in subjects with abnormal phoria. The objective measurement and subjective observation of head posture showed insignificant correction but there was a distinct difference. The former was detail and the latter was discriminate. Conclusions: Presence of abnormal head posture was found in phoric subjects. The results indicate the need to observe habitual head posture at all major positions of gaze in phoria.

Efficacy of levetiracetam in refractory childhood epilepsy (난치성 소아 간질에서 levetiracetam의 효과)

  • Lee, Keon-Su;Kang, Joon-Won
    • Clinical and Experimental Pediatrics
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    • v.53 no.4
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    • pp.571-578
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    • 2010
  • Purpose : To evaluate the efficacy and safety of levetiracetam adjunctive therapy for reducing the rate of seizure frequency in children with intractable pediatric epilepsy. Methods : We reviewed the medical records of 86 patients with intractable pediatric epilepsy who visited our hospital between March 1989 and February 2009. Levetiracetam was included in the previous anticonvulsant regimen for at least 6 months and the reduction in the rate of seizure frequency was determined in follow-up examinations. We analyzed demographic data, seizure types, antiepileptic drug history, levetiracetam dose, adverse effects of levetiracetam therapy, treatment outcome, electroencephalogram findings, etc. Results : More than 50% reduction in the seizure frequency was observed in 62 of the 86 (72.1%) patients; 44 patients (51.1%) became seizure free, while the seizure frequency increased in 5.8% patients. The associations between seizure reduction rate and age, associated diseases, seizure types, and seizure frequency before treatment were not significant. However, the duration of disease, dose of levetiracetam, duration and frequency of anticonvulsant administration before levetiracetam therapy were significantly correlated. Electroencephalogram findings and the cause of epilepsy showed partial correlation. Forty (46%) patients showed adverse symptoms; the symptoms in the order of their frequency were somnolence, hyperactivity, irritability, aggressiveness, tiredness, etc. Conclusion : The findings of our study provide the evidence that levetiracetam adjunctive therapy is efficacious and well tolerated in various refractory childhood epilepsy cases.

Astudy on the dietary intake and health of aged person I -Based on elderly person in Seoul- (노인의 식이섭취실태와 건강상태에 관한 연구 I -서울지역을 중심으로-)

  • Lee, Hyun-Ok;Yum, Cho-Ae;Jang, Myung-Sook
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.15 no.4
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    • pp.72-80
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    • 1986
  • The purpose of this study was to investigate the dietary-intake and that of health by mean of questionarie and interview for male and female old persons living in Seoul area. The contents of study included general aspects, physical status and health, nutrient intake, and food intake frequency. The results from the above survey are summarized as follows ; 1. The age group in the range of 60 to 79 years old was 71%, and the average number of family was 4.9. The educational level was 56% of elderly persons were elementary or middle school graduates . 42.8% of elderly persons had an average monthly income of \490,000 to 300,000. 2. The aged average height, weight, and physical index were 164.9cm, 55.8kg and 20.4 in male, 152.7cm, 46.0kg and 20.3 in female which were lower than the Korean average standard. (male; 167.0cm, 61.0kg, female; 156.0cm, 55.0kg) In the degree of health self-consciousness, percentage distribution of poor and very poor was 29% in male, 59% in female. Among the condition of disease, neuralgia was 23.8%, hypertension was 17.2%, diabetes was 5.4%. 3. Average daily calorie intake was $63.9{\sim}70.4%$ for male and $76.4{\sim}83.9%$ for female which were lower than the Recommended Dietary Allowances for Koreans. Protein intake was $42.9{\sim}57.3g$ (which was $72.8{\sim}82.6%$ RDA) for elderly person, the proportion of animal protein to total protein intake were $24.3{\sim}28.2%$($12.9{\sim}16.2g$). Iron, Vitamin $B_1$, $B_2$ Niacin intake exceeded the RDA, but the intake of Calcium, Vitamin C were far less than that of RDA. 4. In the correlations between nutritional intakes and environmental factors and health, economic living situations and educational level as the factors which might influence the condition of nutritional intake was significant(P<0.01). 5. Food intake frequency of meats, fishes, eggs, for average of $1{\sim}2$ days per week were $44.8{\sim}50.5%$, that of milk and milk products for scarecely week were 42.9.% Correlation of food intake frequency was divided three levels-good, fair, poor. Food intake frequency as the factors which might influence the condition of nutritional intake was significant(P<0.01). The results of the survey reveal that many of elderly show evidence of general nutrient intake deficiency, it requires first of all importance of nutrition to improve nutritional level through to promotion of elderly health.

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A Clinical Study of Facial Paralysis (안명신경 손상 환자의 임상적 고찰)

  • Huh, Choon-Bok;Suh, Tae-Soo
    • Journal of Korean Physical Therapy Science
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    • v.5 no.3
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    • pp.643-650
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    • 1998
  • Facial nerve is subject to injury at any point in the course from the cerebral cortex to the motor end plate in the face, so many etiologic varieties of facial paralysis may be encountered, including trauma, viral infection and the idiopathic. Authors have studied 39 cases of facial paralysis which had experienced of treatment in our department from March, 1996 to March, 1997 at Dong San Medical Center. The results obtained are as follows : 1) The highest age incidence showed 10 cases(24.6%) in 3rd decade 2) Among the total of 39 cases, male were 21 cases(53.8%) and female were 18cases(46.2%). 3) At the involved side, left side were 19 cases(48.7%) and right side were 18 cases(46.2%). 4) The causes of facial paralysis were; idiopathic (Bell's palsy) in 19 cases(48.7%) infectious in 6 cases(15.4%) neoplastic in 6 cases(15.4%) traumatic in 5 cases(12.9%) metabolic in 2 cases(5.1%) congenital in 1 cases(2.6%) 5) In time interval between onset of symptom and treated initial date, 26 cases(66.7%) in below 10 days and 8 cases(20.5%) in 11-20 days 6) Correlation of recovery rate according to the treated duration did not differ significantly 7)Result after treatment were satisfactory

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Spatial Distribution Patterns of Twitter Data with Topic Modeling (토픽 모델링을 이용한 트위터 데이터의 공간 분포 패턴 분석)

  • Woo, Hyun Jee;Kim, Young Hoon
    • Journal of the Korean association of regional geographers
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    • v.23 no.2
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    • pp.376-387
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    • 2017
  • This paper attempts to analyze the geographical characters of Twitter data and presents analysis potentials for social network analysis in geography. First, this paper suggests a methodology for a topic modeling-based approach in order to identify the geographical characteristics of tweets, including an analysis flow of Twitter data sets, tweet data collection and conversion, textural pre-processing and structural analysis, topic discovery, and interpretation of tweets' topics. GPS coordinates referencing tweets(geotweets) were extracted among sampled Twitter data sets because it contains the tweet place where it was created. This paper identifies a correlated relationship between some specific topics and local places in Jeju. This correlation is closely associated with some place names and local sites in Jeju Island. We assume it is the intention of tweeters to record their tweet places and to share and retweet with other tweeters in some cases. A surface density map shows the hotspots of tweets, detecting around some specific places and sites such as Jeju airport, sightseeing sites, and local places in Jeju Island. The hotspots show similar patterns of the floating population of Jeju, especially the thirty-year age group. In addition, a topic modeling algorithm is applied for the geographical topic discovery and comparison of the spatial patterns of tweets. Finally, this empirical analysis presents that Twitter data, as social network data, provide geographical significance, with topic modeling approach being useful in analyzing the textural features reflecting the geographical characteristics in large data sets of tweets.

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The Effect of Self-help Group Program on Adaptation and Quality of Life of Mastectomy Patients (자조집단 프로그램이 유방절제술 환자의 적응과 삶의 질에 미치는 효과)

  • Park, Young-Shin;Lim, Nan-Young
    • The Korean Journal of Rehabilitation Nursing
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    • v.2 no.1
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    • pp.61-71
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    • 1999
  • This quasi-experimental study was intended to test the effect of self-help group program, which is one of the way to enhance adaptation and quality of life to mastectomy patients. Data was collected from July 14, 1998 to Oct. 31, 1998 at two Medical Center in Seoul. The subjects for this study were the patients who had undergone mastectomy and were follow-up ; 14 in experimental group and 14 in control group matched with age and treatment. The instruments for this study were adaptation in Lee(1994)'s physical symptom questionnaire, Zung's Self-rating Depression Scale(SDS, 1965), and Self-rating Anxiety Scale(SAS, 1970), quality of life in Spranger(1996)'s and No(1988)'s Quality of Life Questionnaire. The self-help group program for mastectomy patients was developed based on literature review and pilot study by the investigator. The subjects of experimental group were participated in 6 weeks self-help group program and were received arm and shoulder exercise, informational support, and interpersonal support by group members. The control group were received no intervention, Both group answered questionnaires prior to intervention and 6 weeks later. The data analyzed by frequency, $X^2$-test, Mann-Whitney U test. Wilcoxon Signed Rank test, Pearson's Correlation Coefficient and Stepwise Multiple Regression using SPSS WIN. The results are as follows ; Hypothesis 1. "The experimental group with the self-help group program will have a higher score on adaptation state than control group." was not supported. But the post test score of anxiety and depression in experimental group were declined and the depression score was reduced relatively. Hypothesis 2. "The experimental group with the self-help group program will have a higher score on quality of life than control group." was not supported. But the posttest score of quality of life in experimental group was reduced relatively. Hypothesis 3. "The higher adaptation state of mastectomy patients, the higher quality, of life." was supported(r=,80, p<.001). Additionally, the lower physical symptom, depression and anxiety, the higher quality of life And depression, which was the main predictor of quality of life, accounted for 59.5%, depression and anxiety accounted for 65.5% of the variance in quality of life. In conclusion, when the self-help group program was intervened to mastectomy patients, it was tended to increase quality of life and to reduce depression and anxiety. So self-help group program can be considered useful nursing inter vention effect on adaptation and quality of life of mastectomy patients. With discussion, I suggest repeated further re search on self-help group with appropriate sample size and longitudinal study. Also during adjuvant therapy, it is needed to develop convenient method to be supported from peer group and family, such as computer mediated support group.

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