• Journal of Interdisciplinary Genomics
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• 제4권2호
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• pp.35-38
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• 2022

Background: Prader-Willi syndrome (PWS) is a complex genetic disease associated with growth impairment, severe obesity and metabolic dysfunctions. High proportion of PWS patients are born small for gestational age (SGA) than normal children, which also increase the risk of growth impairment and metabolic dysfunction in PWS. We aimed to compare growth outcome and metabolic profiles between SGA and appropriate for gestational age (AGA) PWS patients. Methods: Data of 55 PWS children and adults aged more than 2 years old (32 male and 23 female, age 2-18.8 years) from single center were studied. Only patients who were treated with GH were included. The clinical characteristics and laboratory findings were reviewed retrospectively. Results: Among 55 subjects, 39 had 15q11-13 deletion and 16 had uniparental disomy (UPD). Twenty (36.3%) were born SGA. All patients received GH treatment, and 11 (20%) discontinued GH treatment. Mean age at GH treatment initiation was 2.5 (range 0.3-12.4) years, and mean duration of treatment was 6.3 (range 1.0-11.3) years. Current height-SDS (-0.36 vs -0.16) and BMI-SDS (1.44 vs 1.33) did not differ between AGA and SGA group. Two patients in SGA group, but none in AGA group had diabetes mellitus. Mean glucose level was also higher in SGA group (100.1 vs 114.4 mg/dL). Conclusion: Our report gives an overview of growth profile and metabolic dysfunctions recorded in GH treated PWS patients. Growth profile did not differ between AGA and SGA group. Glucose level was higher in SGA group, so more careful monitoring and prevention for DM will be required in SGA group.

• Clinical and Experimental Pediatrics
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• 제49권7호
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• pp.703-709
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• 2006

Since the advent of growth hormone(GH), children with a wide variety of growth disorders have received GH treatment. In GH deficiency(GHD), Turner syndrome, chronic renal failure, children born small for gestational age, Prader-Willi syndrome, and idiopathic short stature, the therapeutic effects and safety profile of GH are reviewed. GH therapy has been clearly shown to improve height velocity and final adult height in a variety of pediatric conditions in which growth is compromised irrespective of GHD. Early initiation and individualization of GH treatment has the potential to normalize childhood growth. The supra-physiological doses of GH have been shown to increase height velocity during childhood and final height in non-GHD conditions. Adverse events during GH therapy are uncommon and often not drug related. However continued surveillance into adult life is crucial, especially in children receiving supra-physiological doses or whose underlying condition increases their risk of adverse effects.

• 대한한방소아과학회지
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• 제24권3호
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• pp.121-137
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• 2010

Objectives: The purpose of this study is investigate about chief complaints of pediatric outpatients in the oriental medicine hospital and search for a latest of patients and their symptom. Methods: The study was composed of 3024 new patients aged between 0 and 20 who had been visited pediatrics in Kyung Hee oriental medicine hospital from 2009 March to 2010 February. Results: In age distribution, 1 year old child have most visited, and the number of the patients have fallen sharply as age have increased. The most visited month is August, and the least is November. In systemic division of chief complaints, in order of respiratory part, growth part, restorative herb medicine part, digestive part, neurologic & psychologic part, dermatologic part visited in patients number, and in single chief complaints, in order of growth, restorative herb medicine, anorexia, rhinosinusitis, cold, atopic dermatitis, seizure & epilepsy have visited. As for age and systemic division, between 1 and 6 years old, the patients of respiratory division have most visited, more than 7 years old, growth division. As for age and single chief complaints, in 0 year old, seizure & epilepsy have most visited, between 4 and 6 years old, rhinosinusitis, more than 7 years old, growth. Growth and respiratory division have increased the most in August, restorative herb medicine and digestive division have increased the most in September. In single chief complaints, patients of growth have most visited in most of time, but in September and November patients of restorative herb medicine have visited the most. Conclusions: The most visited division was respiratory part, and the most visited chief complaints was growth. More data of patients should be accumulated for further study, and we expect more specific study would be done about many kinds of disease in basis of this study.

• 한국수산과학회지
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• 제41권4호
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• pp.261-266
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• 2008

The ocypodid crab, Macrophthalmus japonicus, commonly occurs in tidal flats in areas around Korea. We examined the age and growth of M. japonicus collected from the tidal flats of Haui Island in Jeollanamdo, Korea, from January to December 2006. According to variation in the monthly fatness index, the population spawned from June to August. To estimate parameters of growth, frequencies of monthly carapace lengths were analyzed using FiSAT II. The allometry of females differed from that of males. VBGE(von Bertalanffy growth equation) and seasonal VBGE were determined using monthly average carapace lengths for males and females, and an equation for estimating seasonal growth was calculated using regression coefficients.

• 대한치과교정학회지
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• 제22권3호
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• pp.491-507
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• 1992

경북대학교 치과대학에서 두개 안면골 성장에 관한 누년적 연구의 일환으로 남자 26명 여자 21명을 대상으로 평균 연령 8.5세에서 16.5세까지 격년 간격으로 활용한 두부X선 규격사진 235매를 분석하여 이 기간동안 나타난 안면각 부의 성장 변화를 분석하여 다음과 같은 결론을 얻었다. 1. 이 기간동안 두개저에 대하여 하악골이 상악골보다 전방 성장량이 많았다. 2. 하악골은 두개저에 대해 전상방으로 닫히는 방향으로 회전되었다. 3. 전체 하악골 길이(Ar-Gn)에서 뚜렷한 사춘기 급성장을 보였으며 그 시기는 남자 12-14세 여자 10-12세로 신장에서 급성장 시기와 일치하였다. 4. 전체 두개저 길이 (Ba-Na)에서도 사춘기 급성장을 보였고 그 시기는 남자 10-12세 여자는 8-10세로 신장 및 하악골 길이에 비해 2년 정도 빠른 시기에 나타났다. 5. 전${\cdot}$후방 안면 높이(AFH, PFH) 모두에서 최대 성장 시기는 남녀 모두 신장에서 최대 성장 시기와 일치하였다. 6. 남녀별로 각 연령에서 각 계측치의 평균치를 이용하여 전반적 평균 성장 변화도 및 진단용 profilogram을 작성하였다.

• 한국수산과학회지
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• 제51권5호
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• pp.556-565
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• 2018

The age and growth of butter clams Saxidomus purpuratus were estimated using transmitted light on the shells of 364 samples from January 2017 to December 2017 in Jinhae Bay. Based on monthly variation in the marginal index (MI) of the shell, it is assumed that rings are formed once a year during the period from July to August in this species. The relationship between shell length (SL; mm) and shell height (SH; mm) was expressed by the equation SH=0.8053SL-2.9636 ($R^2=0.94$) and between SL and shell width (SW; mm) by the equation SW=0.5648SL-3.7105 ($R^2=0.90$). The relationship between SL and total weight (TW; g) was expressed by the following equation: $TW=0.00009SL^{3.2141}$ ($R^2=0.96$). von Bertalanffy's growth parameters were estimated using the regression wizard in the SigmaPlot computer program (Systat Software, Inc., v. 10.0). The maximum shell length ($SL_{\infty}$) was 126.16 mm, growth rate was 0.2030/year, theoretical age at shell length 0 ($t_0$) was -0.52 years, and asymptotic total weight ($TW_{\infty}$) was 509.17 g. Growth curves for SL and TW fitted to the von Bertalanffy's equation were expressed as follows: $SL_t=126.16(1-e^{-0.2030(t+0.52)})$, $TW_t=509.17(1-e^{-0.2030(t+0.52)})^{3.2141}$.

• 대한예방한의학회지
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• 제14권3호
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• pp.107-115
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• 2010

Objectives : The purpose of this study is to investigate the efficacy of growth exercise program based on Korean medicine. Methods : We recruited fifty two elementary students in a rural area, and measured height, weight, BMI, WHR, and bone age. Questionnaire on sleep, exercise, symptoms based on Korean medicine was performed. Students exercised TaeGuk(太極) Health Gigong(氣功), a growth exercise program 11 times in 6 weeks. Results : Height, weight, BMI and WHR of the subject students were lower than those in the Korean CDC(Center for Disease Control and Prevention) growth chart. There was significantly negative correlation between time of sleep and bone age(p=0.028), but no correlation between time of exercise and bone age(p=0.668). According to diagnosis based on Korean medicine, many students were in weakness of spleen and lung, and bone age according to deficiency of organ showed no significant difference(p=0.774). Satisfaction, impact on time of exercise after program, ideal time for program and impact on reparticipation of program were strong in the questionnaire after growth exercise program(TaeGuk(太極) Health Gigong(氣功)). Conclusions : Korean medicine promotion of health has a salutary effect on elementary school students in rural area by collecting growth and health data and educating easy exercise based on Taichi.

• Asian-Australasian Journal of Animal Sciences
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• 제25권2호
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• pp.151-162
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• 2012

Analysis for back fat thickness (BFAT) and daily body weight gains from birth to the end of a performance test were conducted to find an optimal method for estimation of weaning age effects and to ascertain impacts of weaning age on the growth performance of purebred Berkshire pigs from a closed population in Korea. Individual body weights were measured at birth (B), at weaning (W: mean, 22.9 d), at the beginning of the performance test (P: mean, 72.7 d), and at the end of the performance test (T: mean, 152.4 d). Further, the average daily gains in body weight (ADG) of 3,713 pigs were analyzed for the following periods: B to W (DGBW), W to P (DGWP), P to T (DGPT), B to P (DGBP), B to T (DGBT), and W to T (DGWT). Weaning ages ranged from 17 to 34 d, and were treated as fixed (WF), random with (WC) and random without (WU) consideration of an empirical relationship between weaning ages in the models. WF and WC produced the lowest AIC (Akaike Information Criterion) and least fractions of error variance components in multi-traits analysis, respectively. The fractions of variances due to diverse weaning age and the weaning age correlations among ADGs of different stages (when no overlapping allowed) by WC ranged from 0.09 to 0.35 and from -0.03 to 0.44, respectively. The maximum weaning age effects and optimal back fat thicknesses were attained at weaning ages of 27 to 32 d. With the exception of DGBW, the effects of weaning age on the ADGs increased (ranging from 1.50 g/d to 7.14 g/d) with increased weaning age. In addition, BFAT was reduced by 0.106 mm per increased day in weaning age. In conclusion, WC produced reasonable weaning age correlations, and improved the fitness of the model. Weaning age was one of crucial factors (comparable with heritability) influencing growth performance in Berkshire pigs. Further, these studies suggest that increasing weaning age up to 32 d can be an effective management strategy to improve growth performance. However, additional investigations of the costs and losses related to extension of the suckling period and on the extended range of weaning age are necessary to determine the productivity and safety of this practice in a commercial herd and production system.

• 한국수산과학회지
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• 제54권1호
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• pp.53-63
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• 2021

Age structure and growth of white croaker Pennahia argentata were estimated an analysis of otoliths. Fish specimens were collected from the Southern Sea of Korea from January to December 2018. A thin section method was used for age determination because otoliths of white croaker are oval in shape and large in size. Otoliths were cut vertically into 0.4-0.5 mm thick sections with an electric saw (Micracut 125). Monthly changes in the marginal index indicated that rings (opaque zone) were formed once a year in August. The estimated von Bertalanffy growth equation estimated by a non-linear regression were L∞=34.71 (1-e0.38(t+0.80)). In the present study, the oldest female was 8 years old and the male was 7 years old.

• 수산해양기술연구
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• 제47권3호
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• pp.203-213
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• 2011

The age and growth of flathead grey mullet, Mugil cephalus, were studied using samples collected from the coastal water of Yeosu from September 2009 to August 2010. Spawning season estimated from the gonadosometic index (GSI) was from November to January. A method for increasing the readability of the otolith was described and criteria for the interpretation of otolith was provided. The annual ring was formed in September once a year. Annual ring in otolith for flathead grey mullet is validated for fish aged 1-8 using the marginal increment analysis. Using the sectioned otolith, between reader precision was 84%. Also, Within-reader agreement for sectioned otolith age readings was higher (reader 1=84%, reader 2=87%). The relationship between fork length and total weight was TW=$0.022FL^{2.818}$. The estimated von Bertalanffy growth parameters for the flathead grey mullet were $L_{\infty}$=67.97cm K=0.164/year and $t_o$=-0.81year.