• Journal of the Korean Society for Marine Environment & Energy
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• v.12 no.2
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• pp.91-95
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• 2009

To understand the effect of attachment substrate on the growth of benthic microalgae, we experimentally investigated the growth of benthic microalgae Nitzschia sp. (Jinhae Bay strain) with additions of glass beads in different sizes. The glass beads used in this study are 0.09-0.15 mm (G1), 0.25-0.50 mm (G2), 0.75-1.00 mm (G3) and 1.25-1.65 mm (G4). No addition of glass beads used as controls. Highest specific growth rate (0.37/day) and maximum cell density ($9,232{\pm}840$ cells/mL) of Nitzschia sp. showed at the smallest glass beads (G1), and the specific growth rate and maximum cell density were decreasing with increasing size of glass beads (specific growth rate and maximum cell density of G4 was 0.24/day and $6,397{\pm}524$ cells/mL, respectively). Moreover, specific growth rate of the control experiment (0.23/day) was significantly lower than their of G1 to G3 experiment. The results indicated that the attachment substrate for benthic microalgae as Nitzschia sp. is important factor which affecting the growth rate as well as cell density. Therefore, the physiological experiment of benthic microalgae seems to be necessary to preliminary experiment, which is addition or not of the attachment suitable substrate and the grain size for the target species of benthic microalgae.

• Journal of Life Science
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• v.30 no.7
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• pp.634-639
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• 2020

Starfish are a potential source of marine materials, but their unique odor can limit application. Our previous work suggested that brittle star Ophioplocus japonicus extract could be more effective as a cosmetic material by reducing its odor through a roasting process. However, the biological properties of heat-treated Ophioplocus japonicus extract (HOJE) remain poorly understood. We here examined the anti-inflammatory potential of HOJE in lipopolysaccharide (LPS)-induced RAW 264.7 cells. HOJE significantly inhibits LPS-stimulated nitric oxide (NO) production without affecting cell viability in a dose-dependent manner and suppresses LPS-induced expression of inducible nitric oxide synthases (iNOS) and pro-inflammatory cytokines such as interleukin-6 and -1β. Furthermore, treatment of pyrrolidine dithiocarbamate to inhibit nuclear factor kappa B (NF-κB) signaling accelerated the inhibitory effect of HOJE on NO production, and the translocation of NF-κB p65 from the cytosol to the nucleus was attenuated by HOJE. These results show that HOJE ameliorates inflammation partly through NF-κB signaling which consequently suggests that it has anti-inflammatory potential.

• Korean Journal of Food Science and Technology
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• v.21 no.1
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• pp.120-126
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• 1989

Streptococcus diacetylactis and Leuconostoc cremoris were isolated from commercial culture and the effects of culture conditions on the diacetyl production by these strains and their mixture(1:1) were investigated. Optimum temperatures and culture times for the diacetyl production by Str. diacetylactis, Leu, cremoris and their mixture were 60hr at $22^{\circ}C$(diacetyl content, 2.24ppm), 48hr at $22^{\circ}C$(2.29ppm) and 48hr at $22^{\circ}C$ (2.21ppm), respectively Optimum initial pH for the diacetyl production by Str. diacetylactis, Leu. cremoris and the mixture were all 4.8(4.32, 6.66, 7.30ppm, respectively) and optimum sodium citrate concentrations(%, w/v) were 0.30(2.58ppm), 0.1(2.54ppm) and 0.1(2.52ppm), respectively. The diacetyl contents were gradually increased according as inoculation rates(%, w/v) were increased. The amounts of diacetyl produced under optimum conditions at 24hr incubation by Str. diacetylactis, Leu. cremoris and the mixture were 4.40, 6.59 and 7.25ppm, respectively. The most effective factor affecting diacetyl production under optimum condition was pH.

• Journal of the Korean Geotechnical Society
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• v.34 no.7
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• pp.5-15
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• 2018

The unconfined compressive strength (UCS) test through coring is widely used to determine the reinforcement effect of the ground with grouting. However, the UCS test through coring can disturb the ground, is expensive and takes a lot of time to prepare the specimen. In this study, the factors affecting UCS of microfine cement grouted sand are evaluated and an empirical equation of UCS of microfine grouted sand is suggested. It is observed that UCS increases linearly until 28 days, however, the increasing rate of strength decreases sharply after that 28 days. The W/C ratio is dominant factor influencing UCS and UCS increases exponentially with the decrease of water/cement (W/C) ratio. Also, UCS increases linearly with increasing the relative density ranging from 30% to 70% and with decreasing median particle size. However, in case of W/C ratio=1 and K6 ($D_{50}=0.47mm$), UCS is lower than that of K4 ($D_{50}=1.08mm$) and K5 ($D_{50}=0.80mm$) due to filtration effect. Based on the experimental results, the empirical equation of UCS of microfine cement grouted sand can be expressed as the function of median particle size ($D_{50}$), porosity (n) and W/C ratio.

• Imaging Science in Dentistry
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• v.38 no.3
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• pp.125-132
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• 2008

Purpose : To investigate the effects of irradiation on transforming growth factor ${\beta}_1$ (TGF-${\beta}_1$) mRNA expression and calcific nodule formation in MC3T3-E1 osteoblastic cell line. Materials and Methods : Cells were cultured in alpha-minimum essential medium ($\alpha$-MEM) supplemented with 10% fetal bovine serum and antibiotics. When the cells reached the level of 70-80% confluence, culture media were changed with $\alpha$-MEM supplemented with 10% FBS, 5 mM $\beta$-glycerol phosphate, and $50\;{\mu}g/mL$ ascorbic acid. Thereafter the cells were irradiated with a single dose of 2, 4, 6, 8 Gy at a dose rate of 1.5 Gy/min. The expression pattern of TGF-${\beta}_1$ mRNA, calcium content and calcific nodule formation were examined on day 3, 7, 14, 21, 28, respectively, after the irradiation. Results : The amount of TGF-${\beta}_1$ mRNA expression decreased significantly on day 7 after irradiation of 4, 6, 8 Gy. It also decreased on day 14 after irradiation of 6, 8 Gy. and decreased on day 21 after irradiation of 8 Gy. The amount of calcium deposition decreased significantly on day 7 after irradiation of 4, 8 Gy (P < 0.01) and showed a decreased tendency on day 14, 21 after irradiation of 4, 6, 8 Gy. The number of calcific nodules was decreased on day 7 after irradiation of 4, 8 Gy. Conclusion: Irradiation with a single dose of 4, 6, 8 Gy influences negatively the bone formation at the molecular level by affecting the TGF-${\beta}_1$ mRNA expression that was associated with proliferation and the production of extracellular matrix in MC3T3-E1 osteoblastic cell line.

• Journal of Periodontal and Implant Science
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• v.31 no.4
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• pp.811-822
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• 2001

최근 임플란트를 원하고, 필요로 하는 환자가 증가하면서 술전의 정확한 진단이 보다 중요해졌고 다양한 진단방법이 소개되고 이용되어져 왔다. 그 중 보편적으로 가장 널리 사용되어지는 방법이 방사선 촬영법이고 그 중에서도 파노라마방사선사진이다. 하지만 파노라마방사선사진의 용이함과 간편성에도 불구하고 그 방법 자체가 가지고 있는 한계점 때문에 CT/MPR(Computer Tomography/Multiplanar Reformatting)이 일부 환자에서는 반드시 필요하다는 주장이 대다수이다. 본 연구의 목적은 하악 구치부에 임플란트 시술을 받은 환자를 대상으로 파노라마방사선사진의 확대율을 알아보고 파노라마방사선사진과 CT/MPR에서 치조정-하악관간 거리가 실제 어느 정도 차이를 보이는지, 그리고 CT/MPR에 대한 파노라마방사선사진의 확대율에 환자의 하악골의 경사도와 하악관의 해부학적 위치가 어떤 영향을 미치는지를 알아보는 것이다. 본 연구는 서울대학 치과병원 치주과를 내원하여 하악구치부에 Dental Implant 시술을 받은 15명의 환자, 32개 부위를 대상으로, 임플란트 시술을 위한 술전 파노라마방사선사진과 CT/MPR, 술후의 파노라마방사선사진, CT/MPR상을 자료로, 임플란트가 식립될 위치에서 치조정에서 하악관의 길이, 하악골의 협설폭경, 하악골의 설측면에서 하악관의 수평길이, 임플란트 매식체의 설측에서 하악관까지의 수평거리를 계측하였고 이 해부학적 계측치들이 CT/MPR에 대한 파노라마방사선사진의 확대율과 어떤 상관관계에 있는지 Pearson's correlation coefficient test를 이용해 살펴보았다. 1. CT/MPR에 대한 파노라마방사선사진의 확대율은 CT/MPR상에서 하악골 단면의 협설폭경(Pearson test에서의 상관관계 분석시, 상관계수 r=-0.604), 임플란트 매식체의 설측에서 하악관까지의 수평거리(r=-0.515), 하악골의 설측면에서 하악관까지의 수평거리(r=-0.640)와 뚜렷한 음적 선형관계가 있었다. 2. CT/MPR에 대한 파노라마방사선사진의 확대율은 CT/MPR상에서 하악골의 장축의 각도와는 뚜렷한 양적 선형관계(Pearson test에서의 상관관계 분석시, 상관계수 r=-0.446)가 있었다. 3. 여러 요소중 CT/MPR에 대한 파노라마방사선사진의 확대율과 가장 유의성있는 연관성을 보이는 것은 CT/MPR상에서 하악골의 설측면에서 하악관까지의 수평거리였다(r=-0.640) 4. CT/MPR에 대한 파노라마방사선사진의 확대율은 일반적으로 생각되어지는 파노라마방사선사진의 확대율 125%보다 큰, 약 135%로 나왔다. 이상의 결과로 볼 때, 하악골의 설측면에서 하악관까지의 수평거리가 CT/MPR에 대한 파노라마방사선사진의 확대율에 가장 영향을 미치는 요소로 추정되며 확대율은 125%보다 높은 것으로 나타났다.

• Journal of The Korean Association For Science Education
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• v.22 no.5
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• pp.1010-1029
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• 2002

The purpose of this research was to survey middle school students' preference for science and its causal factors, so as to analyze the causal relationships between them. Preference for science and its causal factors were defined theoretically, and a theoretical model was constructed to measure them and analyze the causal relationship by structural equation modeling. According to the theoretical model and a pilot test, a questionnaire was developed with three parts; the background information of a respondent, the preference for science, and the causal factors of preference. The questionnaire was administered to one class per grade of randomly selected 8 middle schools from 4 areas across the country, and 819 students' data were collected. Preference for science was defined as a state of mind. It revealed to what extent, and how, one likes science. It consisted of 3 categories - 'emotional response', 'behavioral volition', 'valuational comprehension', and each category was divided into two subcategories. Causal factors affecting the preference for science consisted of three categories - personal, educational and social factors, and each was divided into 2 or 3 subcategories. Middle school students' preference for science was middling as a total. Curiosity about contents of science and valuation of science were high, comparatively, but behavioral volition about science was especially low. Students' responses to the causal factors were relatively high in every educational factor and sociocultural valuation of social factors, but relatively low in socioeconomic rewards of social factors, and especially low in personal factors. The causal relationship about the preference for science was investigated by multiple regression analysis and path analysis, using the structural equation model. Multiple regression analysis about the preference for science and its causal factors revealed important factors. The important factors were personal ability, the personal traits, rewards in school science, and contents of school science in order of magnitude of standardized regression coefficient ${\beta}$. Stepwise regression analysis with each of the subcategories of the preference for science as dependent variables showed what factors were important in each subcategory. According to the result of structural equation modeling, personal factors affected 'emotional response' and 'behavioral volition' directly, and social factors affected 'valuational comprehension' directly. Educational factors affected all categories of the preference for science by influencing not only 'emotional response' and 'valuational comprehension' directly, but also 'behavioral volition' indirectly. The way to promote middle school students' preference for science was suggested, based on the analysis result.

• Journal of The Korean Association For Science Education
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• v.36 no.4
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• pp.527-538
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• 2016

The purpose of this study is to select the factors of 'Group scientific creativity' and to find out how 'Group scientific creativity' turns out in the creative problem-solving process of students. To select the factors that affect 'Group scientific creativity', this research extracted 27 influencing factors on the group creativity from the prior study and organized them according to opinions of education experts. To select factors that affect 'Group scientific creativity' in the creative problem-solving process of students, this research analyzed the group problem-solving process that has been done on 72 gifted students for two days. Main results of the study is as follows: First, nine elements such as scientific thinking, scientific knowledge, scientific information-processing capacity, motivation, challenge, age and gender, existence of diversity, creativity educational experience, and the group cohesiveness were selected as human factors. Four elements such as scientific communication skills, scientific inquiry process, autonomy, and leadership were selected as the combining factors. Also, three elements such as the learning environment, teacher types, and compensation were selected as the Environmental factors. Second, it was possible to find that the group scientific creativity influence factors affecting the creative process by analyzing the gifted students in creative-problem solving process. Based on these results, this study described additional points on the factors improving 'Group scientific-creativity.'

• Journal of Dental Rehabilitation and Applied Science
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• v.29 no.3
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• pp.259-271
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• 2013

The purpose of this study was to make the stress distribution produced by simulated different load under two types of internal connection implant system (stepped and tapered type) by means of 3D finite element analysis, The finite element model was designed with the parallel placement of the one fixtures ($4.0mm{\times}11.5mm$) with reverse buttress thread on the mandibular 1st molar. Two models were loaded with 200 N magnitude in the vertical direction on the central position of the crown, the 1.5 mm and 3 mm buccal offset point from the central position of the fixture. The oblique load was applied at the angle of $30^{\circ}$ on the crown surface. Von Mises stress value was recorded and compared in the fixture-bone interface in the bucco-lingual dimension. The results were as follows; 1. The loading conditions of two internal connection implant systems (stepped and tapered type) were the main factor affecting the equivalent bone strain, followed by the type of internal connections. 2. The stepped model had more mechanical stability with the reduced max. stress compared to $11^{\circ}$ tapered models under the distributed oblique loading. 3. The more the contact of implant-abutment interface to the inner wall of implant fixture, the less stress concentration was reduced.

• The Journal of Korean Academic Society of Nursing Education
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• v.8 no.1
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• pp.51-60
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• 2002

The purpose of this study was to identify the relationship between self-esteem, self- efficacy and clinical practice performance, academic achievement, decision making of major field in clinical practice . The study subjects consisted with 244 students from G. junior nursing college that will adapt a new majoring program of clinical nursing practice funded by Ministry of human and resources development. Data were analyzed using descriptive statistics, and t-test, Pearson correlation, and multiple regression. The results of this study were summarized as follows: 1. The students were relatively performed well in clinical practice setting (total M :3.78). The item of student's personal relationship between patients, patient's family, and professional staff showed high score (M=3.96). However students did not feel comfortable to communicate with patients, patient's family and professional staffs in clinical setting(mean=3.56). 2. Students who had experiences of temporal absence from school showed significant difference in the variable of academic achievement and decision making of major field in clinical practice Students who entered to nursing school with self-motive revealed statistically significant difference in the variable of clinical practice performance, academic achievement, self-esteem, self-efficacy, and decision making of major field in clinical practice. 3. There was a significant correlation between self-esteem and clinical practice performance, (r=.512, p<.000). And the relation between self-esteem and decision making of major field in clinical practice was significantly correlated(r=.377, p<.000). Self-efficacy and clinical practice performance(r=.567, p<.000), and decision making of major field in clinical practice (r=.441, p<.000) showed significant correlations. Also relation between academic achievement and self-esteem reveled a significant correlation(r=.129, p<.05) but correlation between self-efficacy and academic achievement was not significant. 4. Correlation between clinical practice performance and decision making of major field in clinical practice also identified a significant relation(r=.498, p<.000). 5. Self-esteem and self-efficacy variables predicted clinical practice performance and explained 37.7% of clinical practice performance. 6. Aptitude and personal interests(m=4.07) reveled important factor affecting to select majoring area in clinical practice, and advice from parents reflected low percentage on selecting places(m=2.42). In conclusion, the variables of self-esteem and self-efficacy showed significant correlations with the variables of student's clinical practice performance, academic achievement, and decision making of major field in clinical practice. Thus it is recommended that student's affective domain of self-esteem and self-efficacy should be developed by nursing intervention before clinical nursing education.