• 제목/요약/키워드: Affecting

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Interactive Effect of Bisphenol A (BPA) Exposure with -22G/C Polymorphism in LOX Gene on the Risk of Osteosarcoma

  • Jia, Jie;Tian, Qing;Liu, Yong;Shao, Zeng-Wu;Yang, Shu-Hua
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권6호
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    • pp.3805-3808
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    • 2013
  • Background: Osteosarcomas have many established risk factors, both genetic and environmental, but by themselves these explain only part of the total cancer incidence. Bisphenol A (BPA) is an environmental estrogen associated with risk of several kinds of tumour. The lysyl oxidase gene (LOX) may also contribute to risk of tumours including osteosarcomas. Here, we investigated possible interactions of BPA and a LOX polymorphism on the risk of osteosarcoma. Method: The present hospital-based case-control study included 106 cancer patients and 112 controls from a Chinese population. Internal burden of BPA exposure was assessed using high-performance liquid chromatography-mass spectrometry (HPLC-MS) method. Genotypes were determined using PCR-RFLP methods. Results: Compared with those in low BPA exposure group, subjects with BPA more than or equal to median value had significant increased risk of osteosarcoma among subjects who carried GC or CC genotypes. A significant interaction with BPA level and the -22G/C polymorphism was observed for osteosarcoma overall, osteosarcoma affecting knee and osteosarcoma affecting hip, as $P_{forinteraction}$ = 0.036 for osteosarcoma overall; $P_{forinteraction}$ = 0.024 for osteosarcoma affecting knee; and $P_{forinteraction}$ = 0.017 for osteosarcoma affecting hip. Conclusions: The results suggest that BPA exposure interacts with the -22G/C polymorphism of the LOX gene to increase the risk of osteosarcoma.

중학교 과학 교과서에 기술된 끓는점 측정 방법 분석 및 개선점 제안 (Analysis and Improvement for Method of Boiling Point Measurement described in Middle School Science Textbooks)

  • 노을;장낙한
    • 과학교육연구지
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    • 제39권3호
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    • pp.446-456
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    • 2015
  • 2009 개정 7학년 과학 1 교과서에 제시된 끓는점 실험을 할 때 측정에 영향을 미치는 요인을 분석하였으며, 실험을 통해 교과서에 제시된 실험 방법의 오류를 확인한 후 이를 개선하기 위한 방안을 제안하였다. 2009 개정 7학년 과학 1 교과서 9종에 제시된 끓는점 측정 실험을 분석하여 끓는점에 영향을 미치는 요인을 찾아보았더니 온도계의 종류, 가열 도구, 마개 밀폐 여부, 온도계의 위치, 가열 용기의 모양, 물질과 가열용기의 부피비와 같은 6종류의 요인을 확인하였다. 물질의 끓는점을 측정하는 실험을 수행할 때, 둥근바닥 플라스크의 10%만 물질로 채운 후 MBL 온도 센서를 가지 부근에 위치하게 하고, 마개를 막아 핫플레이트로 가열하는 것이 가장 효과적인 결과를 나타내는 것을 확인하였다. 이를 토대로 2009 개정 7학년 과학 1 교과서 9종과 비교하였더니 대부분의 교과서에서 수정되어야 할 점이 많은 오류가 있음을 발견하였다. 따라서 끓는점 측정에 대한 학생들의 학습 이해도를 높이고 오개념을 방지하기 위해 과학 1 교과서에 제시되어 있는 실험들이 보다 정확하게 개선되어야 할 것이다.

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공급사슬관리시스템의 활용에 영향을 미치는 요인에 관한 연구 (The Factors Affecting on The Implementation of Supply Chain Management System)

  • 홍현기
    • 디지털융복합연구
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    • 제13권10호
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    • pp.255-261
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    • 2015
  • 본 연구에서는 경영전략의 하나로 활용되고 있는 공급사슬관리(Supply Chain Management : SCM)시스템의 활용에 영향을 미치는 요인들을 분석하였다. 요인들을 도출하기 위하여 기존의 연구들을 바탕으로 SCM시스템을 구축하여 활용하고 있는 생산기업으로 부터 수집된 데이터로 실증분석을 하였다. 설문지 내용은 Likert 5점 척도로 구성하였고, 인터넷 설문을 실시하였다. 연구 모델을 구조방정식을 통해서 분석한 결과 공급사슬관리시스템의 활용에 영향을 미치는 요인들은 기업의 IT-활용능력과 기업의 공급사슬관계로 함축되었다. 이들 요인들의 관계는 구조방정식(Structural Equation Model : SEM) 기법을 통해 상호연관관계를 분석하였다. 본 연구는 한국의 제조기업 들에게 공급사슬관리시스템 구축 및 활용 있어서 고려해야할 요인들에 대한 이해를 증진시키고, 효율적인 공급사슬관리시스템을 구축할 수 있는 방향을 제시해 줄 것이다.

성인 남성의 금연 준비단계에 영향을 미치는 요인 (Factors Affecting Preparation Stage to Quit Smoking in Men)

  • 연정운;김형수;이건세;장성훈;최희정;함은미;명준표
    • 대한간호학회지
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    • 제42권3호
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    • pp.377-384
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    • 2012
  • Purpose: This study was done to investigate factors affecting preparation stage to quit smoking in men. Methods: Based on data from the Community Health Survey conducted in Chungbuk Province in 2008, we estimated rates and odds ratio (OR) of smoking cessation intention for 2,639 men who were current smokers. Multivariate logistic regression analyses were used to identify factors affecting preparation stage to quit smoking. Results: Among current male smokers, the rate of smoking cessation intention was 17.1%. The OR of factors affecting smoking cessation was as follows: Compared to men with middle school education, the OR for rate of smoking cessation intention in men with high school education was 1.47 (p=.018), and for college or higher, 1.55 (p=.017). Compared to being single, the OR for cohabitation after marriage was 1.61 (p=.011) and living alone after marriage, 2.23 (p=.005). The OR for attempt to quit smoking, exposure to secondhand smoke and participation in smoking education were 6.80 (p<.001), 1.32 (p=.020) and 1.69 (p=.005), respectively. Conclusion: Results of this study show that it is necessary to decrease exposure to secondhand smoke and to increase participation in smoking cessation education targeting current smokers to move them from precontemplation or contemplation stage to preparation stage.

An Empirical Study of Knowledge Sharing Behavior of the SNS: A Case Study of "Sina Weibo"

  • Lu, Jinku;Kim, Jongki
    • Asia pacific journal of information systems
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    • 제26권3호
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    • pp.367-384
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    • 2016
  • Social networking services (SNS) have become a significant platform for Internet users to obtain knowledge and information. Users can share messages mutually via this platform. This kind of sharing enables users to exchange and gain useful information. However, in recent years, the crisis of stickiness has appeared in SNS, calling attention to the social network industry. Relevant professionals explain that the interest of users in sharing knowledge on SNS websites and applications may gradually decrease, eventually leading to users giving it because the platforms utilize simple and uninteresting methods to attract active participation from users. However, factors affecting the knowledge sharing on SNS websites and applications should be identified clearly through studies. Sina Weibo is one of the largest SNS platforms in the world, and studies on the factors affecting knowledge sharing of users could be valuable in addressing this issue. This paper establishes the theoretical analysis model of knowledge sharing in SNS sites and applications, analyzes the factors affecting knowledge sharing on these sites, and proposes the corresponding strategies to address the issues. Using questionnaire surveys on Sina Weibo users, this article will discuss the factors affecting knowledge sharing, and analyze these factors on SNS as well as improve the stickiness of users to achieve the aim of SNS platforms enabling the expansion of the range of users. The study will discuss theoretical foundations and the hypotheses that arise. The method of study will also be discussed. The study concludes with theoretical implications, practical implications, limitations, and future research opportunities. The results of this study could aid researchers in understanding the underlying reasons for social network activities as well as for SNS developers in improving SNS services.

ANALYSIS OF SPATIAL FACTORS AFFECTING DENGUE EPIDEMICS USING GIS IN THAILAND

  • Nakhapakorn Kanchana;Tripatht Nitin;Nualchawee Kaew;Kusanagt Michiro;Pakpien Preeda
    • 대한원격탐사학회:학술대회논문집
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    • 대한원격탐사학회 2005년도 Proceedings of ISRS 2005
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    • pp.774-777
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    • 2005
  • Dengue Fever(DF) and Dengue haemorrhagic fever(DHF) has become a major international public health concern. Dengue Fever(DF) and Dengue haemorrhagic Fever (DHF) is also still the major health problem of Thailand, although many campaigns against it have been conducted throughout the country. GIS and Remotely Sensed data are used to evaluate the relationships between socio-spatial, environmental factors/indicators and the incidences of viral diseases. The aim of the study is to identify the spatial risk factors in Dengue and Dengue Haemorrhagic Fever in Sukhothai province, Thailand using statistical, spatial and GIS Modelling. Preliminary results demonstrated that physical factors derived from remotely sensed data could indicate variation in physical risk factors affecting DF and DHF. The present study emphasizes the potential of remotely sensed data and GIS in spatial factors affecting Dengue Risk Zone analysis. The relationship between land cover and the cases of incidence of DF and DHF by information value method revaluated that highest information value is obtained for Built-up area. A negative relationship was observed for the forest area. The relations between climate data and cases of incidence have shown high correlation with rainfall factors in rainy season but poor correlation with temperature and relative humidity. The present study explores the potential of remotely sensed data and GIS in spatial analysis of factors affecting Dengue epidemic, strong spatial analysis tools of GIS. The capabilities of GIS for analyst spatial factors influencing risk zone has made it possible to apply spatial statistical analysis in Disease risk zone.

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뇌혈관질환 노인을 돌보는 가족원의 우울과 삶의 질에 영향을 미치는 요인에 관한 연구 (A Study of Depression and Quality of Life in Family Care Givers of the Stroke Elderly Patient)

  • 노국희
    • 한국보건간호학회지
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    • 제14권1호
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    • pp.41-60
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    • 2000
  • This study was designed and undertaken to identify the related factors of family caregivers' depression & quality of life with stroke elderly patient. The data was collected from August 16th to September 5th. 1999. The subjects in this study were 70 caregivers and 70 patients with stroke who were hospitalized in 2 oriental medicine hospitals and 3 hospitals located in Junla-buk do. The data was analized using percentage. means. t-test. ANOVA and pearson's correlation coefficients, step-wise multiple regression done with the SAS program. The results of this study are as follows; 1. The score for family caregivers' depression was 45.2 when total score was 80. The family caregivers who got more than 50 scores belongs to highly depression group amount to $29\%$. 2. The score for family caregivers' quality of life was 37.04 when total score was 56. 3. In the significant relationship between family caregivers' depression and general characteristics of the family caregivers ; age. sex, income. In the significant relationship between family caregivers' quality of life and general characteristics of family caregivers: age, education, income. In the significant relationship between family caregivers' depression and quality of life and general characteristics of stroke elderly patient ; sex. 4. The depression degree showed significant differences in the variables of family caregiver's physical health(r=-0.307, p=0.011), stress(r=0.463. p=0.011). social support (r=-0.241. p=0.046) and elderly stroke patient's ADL(r=-0.313, p=0.009). The quality of life degree showed significant differences in the variables of family caregivers' depression(r=-0.564, p=0.001), stress(r=-0.322, p=0.008), social support (r=0.353. p=0.003). 5. The most important variable affecting family caregiver's depression was caregivers' physical symptom which accounted for $32.0\%$ of the total variance in which multiple regression analysis. Total variance affecting the family caregivers' depression was $49\%$. The most important variable affecting family caregivers' quality of life was caregivers' depression which accounted for $48\%$ of the total variance in which multiple regression analysis. Total variance affecting the family caregivers' quality of life was $61\%$.

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일부지역 대학생의 성 경험 영향요인 (Affecting Factors Sexual Experience Among College Students)

  • 정애화;정유진;김민영
    • 한국산학기술학회논문지
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    • 제16권1호
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    • pp.555-563
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    • 2015
  • 본 연구는 대학생의 성 경험 영향요인을 확인하고, 변인간의 관계를 규명하여 대학생의 성 교육 프로그램 개발의 기초 자료를 제공하고자 한다. 본 연구는 2013년 5월 20일부터 6월 20일 동안 경산시에 위치한 일개 대학교 548명의 대학생을 대상으로 실시하였다. 대상자에서 성 경험에 대한 차이가 있는 것은 연령, 주거형태, 출신고등학교, 이성교제경험, 부모의 성 태도로 나타났으며, 대상자의 성별에 따라 유의하게 나타났다. 성 경험이 있는 대상자의 성 경험 시기는 '고등학교', 성관계 상대에서는 '당시 교제상대', 피임에 대해서도 '할 때도 있고 하지 않을 때도 있다', 성 관계 장소에 대해서 '본인 또는 상대 집'이라고 많이 응답하였다. 성 지식, 성 태도, 성 주체성을 분석한 결과에서는 성 태도와 성 주체성이 상관관계를 나타났다. 성 경험에 영향을 미치는 요인에서는 나이, 부모의 성 태도, 성 지식, 성 태도가 영향요인으로 유의하게 나타났다. 본 연구결과를 통하여 성 교육 프로그램 적용시기와 성 교육 프로그램 개발과정에 고려해야 할 영향 요인을 나타내므로 이를 바탕으로 성 교육 프로그램을 개발 및 적용한다면 대학생의 성 교육 프로그램의 효율성과 접근성을 향상시킬 수 있을 것이다.

한국 여성근로자의 직업관련 건강상태와 영향요인 (Health Status and Affecting Factors related to Job among Korean Women Employees)

  • 홍은영;김상돌
    • 한국산학기술학회논문지
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    • 제13권9호
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    • pp.4107-4118
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    • 2012
  • 본 연구는 한국 여성근로자의 직업관련 건강상태와 영향요인을 파악하기 위한 서술적 상관관계연구이다. 본 연구자료는 한국산업안전보건공단 한국산업안전보건연구원에서 취업자 근로환경 전국표본조사를 위해 2006년도 시행한 근로환경조사를 바탕으로 20-64세 여성근로자들로부터 얻었다. 한국 여성근로자의 직업관련 신체적 건강상태는 교육수준, 가정내 주수입원 종류, 회사규모, 고용형태, 주당 근로시간, 교대근무여부, 직무요구도 등에서 유의한 차이가 있었다. 심리적 건강상태는 교육수준, 월 평균소득, 가정내 주수입원 종류, 주당 근로시간, 교대근무 여부, 감정노동여부, 직무요구도, 직무자율성, 물리적 위험, 화학적 위험, 근골격계 위험부담요인 등에서 유의한 차이가 있었다. 직업관련 신체적 심리적 건강상태에 영향을 주는 요인을 알아보기 위해 단계적 중회귀분석을 한 결과 신체적 건강상태와 심리적 건강상태에 가장 큰 영향을 주는 요인은 근골격계 부담 이었고 설명력은 각각 6.12%, 2.97% 이었다. 그러므로 근골격계 부담요인 감소를 위한 작업장 환경조성과 체계적인 건강관리 및 보건교육이 필요할 것으로 사료된다.