• Journal of Ginseng Research
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• v.41 no.3
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• pp.373-378
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• 2017

Ocotillol-type saponins are one kind of tetracyclic triterpenoids, sharing a tetrahydrofuran ring. Natural ocotillol-type saponins have been discovered in Panax quinquefolius L., Panax japonicus, Hana mina, and Vietnamese ginseng. In recent years, the semisynthesis of 20(S/R)-ocotillol-type saponins has been reported. The biological activities of ocotillol-type saponins include neuroprotective effect, antimyocardial ischemia, antiinflammatory, antibacterial, and antitumor activities. Owing to their chemical structure, pharmacological actions, and the stereoselective activity on antimyocardial ischemia, ocotillol-type saponins are subjected to extensive consideration. In this review, we sum up the discovery, semisynthesis, biological activities, and metabolism of ocotillol-type saponins.

• Proceedings of the Korean Vacuum Society Conference
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• 2012.02a
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• pp.427-427
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• 2012

Ferroelectric-gate field effect transistor based memory using a nanowire as a conducting channel offers exceptional advantages over conventional memory devices, like small cell size, low-voltage operation, low power consumption, fast programming/erase speed and non-volatility. We successfully fabricated ferroelectric nonvolatile memory devices using both n-type and p-type Si nanowires coated with organic ferroelectric poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] via a low temperature fabrication process. The devices performance was carefully characterized in terms of their electrical transport, retention time and endurance test. Our p-type Si NW ferroelectric memory devices exhibit excellent memory characteristics with a large modulation in channel conductance between ON and OFF states exceeding $10^5$; long retention time of over $5{\times}10^4$ sec and high endurance of over 105 programming cycles while maintaining ON/OFF ratio higher $10^3$. This result offers a viable way to fabricate a high performance high-density nonvolatile memory device using a low temperature fabrication processing technique, which makes it suitable for flexible electronics.

• Current Research on Agriculture and Life Sciences
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• v.16
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• pp.37-44
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• 1998

The estimation of PMP (Probable Maximum Precipitation) and the analysis of characteristics of PMF (Probable Maximum Flood) according to the types of time distribution of rainfall and variations of base flow for the determination of design flood of major hydraulic structures in the watershed area of Wi stream were analysed. The PMP was estimated by the hydro-meteorological method suggested by the guideline of the World Meteorological Organization(WMO). The Blocking method was cited to transpose from PMP to PMS (Probable Maximum Storm) with time distribution. The unit hydrograph, applied for the estimation of PMF was derived by Clark's method. The summaryzed results : (1) The 72 hrs duration PMP in the area is 477.3mm which is 80mm less than the PMP map in Korea and 134 mm lager than the maximum precipitation of 342.9mm in Taegu, near the Wi stream watershed. (2) According to the types of time distribution and variations of base flow, the ranges of PMF for advanced type, central type and delayed type are 3,145.3~3,348.3cms, 3,774.6~3,977.7cms and 3,814.6~4,017.3cms, respectively. Those mean that peak discharge of advanced type is 600cms less than the central type and delayed type. (3) Delayed type among three types by Blocking method has been estimated the largest PMF of 4,017.3cms, and the advanced type has been estimated the smallest PMF of 3,145.3cms. The mean value of the peak PMF of 3,653.6cms may probably be resonable PMF in the Wi stream watershed. The mean PMF could probably be 1.7 times lager than the result of Gajiyama's equation. It is equivalent to the flood of return period 1,000 to 10,000 yrs.

• Journal of Information Display
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• v.2 no.3
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• pp.72-77
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• 2001

Amorphous silicon thin-film transistors (a-Si TFTs) were incorporated into Mo-tip-based triode-type field emitters and diode-type ones of carbon nanotubes for an active-matrix cathode (AMC) plate of field emission displays. Also, we developed a novel surface-treatment process for the Mo-tip fabrication, which gleatly enhanced in the stability of field emission. The field emission currents of AMC plates on glass substrate were well controlled by the gate bias of a-Si TFTs. Active-matrix field emission displays (AMFEDs) with these AMC plates were demonstrated in a vacuum chamber, showing low-voltage matrix addressing, good stability and reliability of field emission, and highly uniform light emissions from the anode plate with phosphors. The optimum design of AMFEDs including a-Si TFTs and a new light shield/focusing grid is discussed.

• Biomolecules & Therapeutics
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• v.26 no.5
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• pp.439-445
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• 2018

T-type calcium channels are low voltage-activated calcium channels that evoke small and transient calcium currents. Recently, T-type calcium channels have been implicated in neurodevelopmental disorders such as autism spectrum disorder and neural tube defects. However, their function during embryonic development is largely unknown. Here, we investigated the function and expression of T-type calcium channels in embryonic neural progenitor cells (NPCs). First, we compared the expression of T-type calcium channel subtypes (CaV3.1, 3.2, and 3.3) in NPCs and differentiated neural cells (neurons and astrocytes). We detected all subtypes in neurons but not in astrocytes. In NPCs, CaV3.1 was the dominant subtype, whereas CaV3.2 was weakly expressed, and CaV3.3 was not detected. Next, we determined CaV3.1 expression levels in the cortex during early brain development. Expression levels of CaV3.1 in the embryonic period were transiently decreased during the perinatal period and increased at postnatal day 11. We then pharmacologically blocked T-type calcium channels to determine the effects in neuronal cells. The blockade of T-type calcium channels reduced cell viability, and induced apoptotic cell death in NPCs but not in differentiated astrocytes. Furthermore, blocking T-type calcium channels rapidly reduced AKT-phosphorylation (Ser473) and $GSK3{\beta}$-phosphorylation (Ser9). Our results suggest that T-type calcium channels play essential roles in maintaining NPC viability, and T-type calcium channel blockers are toxic to embryonic neural cells, and may potentially be responsible for neurodevelopmental disorders.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.36 no.6A
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• pp.558-567
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• 2011

In this paper, we propose a partial full duplex relay scheme for 3GPP (3rd Generation Partnership Project) LTE (Long Term Evolution)-Advanced system using a Type 1 relay. The Type 1 relay as inband relay is prohibited to transmit and receive simultaneously because of self-interference. Therefore, the Type 1 relay cannot receive synchronization signals which are transmitted to eNB. To overcoming this problem, we propose the partial full duplex relay scheme which transmits to R-UE (Relay-User Equipment) and receives from eNB (evolved NodeB) simultaneously when eNB and the Type 1 relay transmit subframes which have synchronization signals. Additionally, for solving self-interference, the Type 1 relay transmitter and receiver antennas are sufficiently sufficiently isolated and self-interference cancellation is applied for the self-interference signal from the relay transmitter. Thus, the partial full duplex relay scheme can receive synchronization signals from eNB and solve the problems of conventional solutions and we propose the partial channel estimation scheme for partial full duplex relay scheme using SCI. By extensive computer simulation, we verify that the partial full duplex relay scheme is attractive and suitable for the Type 1 relay system.

• Journal of Electrical Engineering and Technology
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• v.8 no.6
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• pp.1424-1430
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• 2013

This paper presents design procedure of the magnetic bearings used for high-speed electric machines and flywheel energy storage systems. Magnetic bearing can be categorized by inner-rotor type and outer-rotor type according to the position of the rotary disc. These two types are applicable based on application environments such as application space, required attraction force, and controllability. Magnetic bearing is generally designed based on the ratio (geometrical coefficient or geometrical efficiency) of pole width to rotor journal radius but proper ratio is only decided by the analysis. This is the difficulty of the magnetic bearing design. In this paper, proper design technology of the inner-rotor type and outer-rotor-type eight pole magnetic bearings is introduced and compared with the FEM analysis results, which verifies the proposed design procedure is suitable to be applied to the design of the magnetic bearings for the industrial applications and flywheel energy storage system.

• Journal of the Korean Mathematical Society
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• v.50 no.3
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• pp.493-507
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• 2013

We construct a new family of simply connected minimal complex surfaces of general type with $p_g$ = 1, $q$ = 0, and $K^2$ = 3, 4, 5, 6, 8 using a $\mathbb{Q}$-Gorenstein smoothing theory.

• Ceramist
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• v.21 no.3
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• pp.283-292
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• 2018

Here, we introduce various type of inorganic nanostructure synthesized with functional nanoparticles and silica. From two decades ago, functional inorganic nanoparticles have been synthesized and highlighted, now we moved to next level of wet-chemical synthesis. By integrating functional nanoparticles with silica, we were able to synthesize multi-functional nanostructure, which expand the applications of nanoparticles to catalyst, drug carrier, sensors. In this context, silica has been spotlighted due to its versatility. Silica has highly biocompatible, relatively transparent and stable under harsh conditions. Thus it can be used as good supporter to synthesize complex multi-functional nanostructure when mixed with other functional nanoparticles. A various shape of complex nanostructures have been synthesized including core-shell type, yolk-shell type and janus type etc. In this paper, we have described the purposes of synthesizing silica noncomplex and various case studies for biomedical applications and self-assembly.

• Applied Microscopy
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• v.46 no.2
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• pp.110-115
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• 2016

Transmission electron microscopy (TEM) is a powerful tool for analyzing a broad range of materials and provides localized information about the microstructure. However, the analysis results are strongly influenced by the quality of the thin foil specimen. Sample preparation for TEM analysis requires considerable skill, especially when the area of interest is small or the material of interest is difficult to thin because of its high hardness and its mechanical instability when thinned. This article selectively reviews recent advances in TEM sample preparation techniques using a tripod polisher. In particular, it introduces two typical types (fl at type and wedge type) of TEM sample preparation and the benefits and drawbacks of each method; finally, a method of making better samples for TEM analysis is suggested.