• 환경생물
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• 제24권2호
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• pp.155-159
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• 2006

To reveal effects of gamma-irradiation with various doses on the expressions of C4H and F5H genes, the transcription levels of OsC4HL and OsF5HL were investigated in leaves and stems of two rice cultivars, Ilpoombyeo and IR-29, after the irradiation with 5, 10, 50, or 100 Gy for 4 h. In overall pattern of 24 h after the irradiation, the transcription levels of the two genes increased with the increasing doses of radiation in the leaves of both cultivars, except that of OsC4HL in IR-29. However, in the stems, the transcription level of OsF5HL increased in Ilpoombyeo and decreased in IR-29 dose-dependently, while that of OsC4HL decreased in Ilpoombyeo with the increasing doses of radiation and remained constant in IR-29. When the expressions of OsC4HL and OsF5HL were investigated in a time-course after the irradiation with 100 Gy, they reached their highest levels in the leaves of both cultivars 5 hand 72 h after the irradiation, respectively. Therefore, we suggest that the expressions of OsC4HL and OsF5HL, which involved in the same phenylpropanoid pathway, are differentially regulated during the post-irradiation period, showing different cultivar and tissue specificity. Furthermore, the dose dependency of the gene expressions is also discussed immediately after the irradiation.

• International Journal of Quality Innovation
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• 제8권3호
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• pp.173-187
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• 2007

Many 6-sigma innovation companies are obtaining ISO9000 series or ISO/TS16949 certifications. However, not many of them have considered the integrated management of ISO/TS16949 at the time of 6-sigma introduction. ISO/TS16949 focuses on the process of an overall company. In particular, APQP (Advanced Product Quality Planning) requires that from the beginning all the planning should have a clear quality planning business process. Each company can decide the best course of action to suit its individual needs. Lean DFSS in 6-sigma offers the concrete development steps of the product development process. And if analyses of Input, Output, Target, Process, KSF, KPI, and FMEA is done in each process and clearly defined in APQP, mutual organic and effective systems can be initially achieved.

• 대한치과의사협회지
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• 제10권2호
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• pp.87-90
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• 1972

The carcinoma of the maxillary sinus occupies about 0.25% of all human cancers. The radiations therapy for maxillary sinus hs not been practiced widely in this country. The authors treated a case of relatively advanced maxillary sinus cancer with combined radium and external irradiation with a succesful result. The clinical course and treatment are introduced and evaluated in detail. The authors believe that the carcinoma of the maxillary sinus is a curable disease even though it is relatively advanced one.

• Journal of Chest Surgery
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• 제23권3호
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• pp.537-541
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• 1990

Early esophageal carcinoma is defined as a lesion wherein invasion is confined to the mucosa and submucosa without metastasis to lymph node or other organs. Postoperative 5-year survival rate for early esophageal carcinoma is much superior than advanced carcinoma. Unfortunately, because of the anatomic characteristic of esophagus and absence of specific early symptoms, detection is frequently belated, and advanced disease is present at the time of the initial diagnosis. We experienced 2 cases of early esophageal carcinoma. They complained no specific symptoms. The diagnosis was made by barium esophagogram, esophagofiberscopy with dye staining and endoscopic biopsy. We performed esophagectomy with esophagogastrostomy. All had good postoperative course without any complication. We concluded that the combined use of double contrast radiography, esopagofiberscopy aided by intraluminal staining with Toluidine blue or Lugol`s solution, and endoscopic biopsy is very important in the diagnosis of early esophageal carcinoma in high risk patient group.

• 한국콘텐츠학회논문지
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• 제20권1호
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• pp.605-616
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• 2020

본 연구에서는 유아교육의 메이커 교육 적용 가능성을 탐색하기 위해 메이커 교육에 대한 교사의 인식을 알아보고 메이커 교육에 대한 교사 교육 과정 구성 방향을 제시하고자 한다. 이를 위해 유아교사를 대상으로 메이커 교육 인식에 대한 설문조사를 실시하였고 자료 분석 결과 메이커 교육에 대한 개념 및 의미와 교육환경에 대한 인식은 낮게 나타난 반면 메이커 교육의 효과, 중요성, 가치, 지속적 적용과 발전가능성은 높게 인식하고 있는 것으로 나타나 메이커 교사교육과 교육환경 구성의 필요성이 제시되었다. 조사결과를 기초로 교사 교육과정 구성안은 크게 기본과정과 심화과정으로 분류하였다. 기본과정에는 메이커 교육과 메이커 스페이스의 개념 및 의미 등에 대한 기반 내용을 포함시켜 인식과 이해를 높이고자 하였으며 심화과정에서는 다양한 도구, 재료 및 디지털 매체 활용방법과 메이커 교육 수행 방법 및 평가에 대한 내용을 포함하여 메이커 교육활용 능력을 양성하고자 하였다. 메이커 교육을 위한 교사 교육과정 구성안은 향후 교사교육 프로그램을 개발하고 교사들의 디지털 수업역량을 강화하는데 기본방향을 제안해 줄 수 있다.

• 한국산학기술학회논문지
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• 제16권6호
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• pp.3963-3972
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• 2015

본 논문은 문제기반학습 연계의 시뮬레이션 교육이 MBTI 성격유형에 따라 비판적 사고, 문제해결 능력 및 학습동기에 미치는 효과를 분석하고자 시도되었다. 간호 전공심화생 19명을 대상으로 첫 6주간 문제기반학습 패키지로 학습하고, 그후 5주는 문제기반학습연계의 통합시뮬레이션 교육을 받은 후 비판적 사고, 문제해결 능력, 학습동기를 평가하고 이를 MBTI 성격유형에 따라 분석하였다. 그 결과 외래근무 심화생의 학습동기와 이전에 시뮬레이션 교육경험이 없는 심화생의 비판적 사고가 유의하게 높았으며, 논리적이고 창의적인 유형(NT)에서 비판적 사고가 유의하게 높았다. 학습에 대한 태도와 동기는 성격유형과 유형들이 가지는 특징에 영향을 받을 수 있으므로, 문제기반학습 기반의 시뮬레이션 교육의 효과를 높이기 위해서는 대상자들의 성격유형을 고려하고, 특징들을 반영한 간호교육 프로그램이 개발되어야 할 것이다.

• 한국식생활문화학회지
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• 제8권3호
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• pp.231-241
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• 1993

A survey of food intake and waste rate on 60 Korean style restaurants in Seoul. The results were summarized as follows: 1. The total served weight of Pibimbab(mixed rice) was 475.66 g per person, waste rate was 6.0%, frequent side dishes were bae-chu kimchi, kak-du-gi, suk-ju-namul by the order. 2. Han- jeong-sik(Korean style full course food) were served with many kinds and varied numbers of side dishes, and waste rate of those were higher than other menu items. 3. The average serving size of Naeng-myeun(Cold noodle) was 641.00 g, and the waste rate was 11.1%. The waste rate of side dishes was about zero. 4. Man-du kuk(dumpling soup) was served 695.34 g. Most of side dishes served has high waste rate which is more than 50%, average. 5. Seol-nong tang(meat soup) was served 755.70 g, side dishes of that were simple such as kak-du-ki or paek kimchi. The average waste rate of side dishes was about 40%. Yuk-gae-jang(Hot meat soup) was 494.83 g a person, waste rate of that were 24.1%, and minimum and maximum waste rate of side dishes were 3.3, 100%, respectively. 6. Kimchi chigae(Kimchi stew) and Doen-jang chigae(fermented soy stew) were served with varied number of side dishes. 7. Deong-sim gui(grilled meat) and Pulgogi(grilled meat with sauce) were served 196.83 g and 308.98 g. The average waste rate of those were 0.7% and 5.8%, respectively. But waste rate of side dishes was 33%. We would like to decrease waste rate by proposing recommended items and weight of some food for ${\ulcorner}Good{\;}Menu{\lrcorner}$.

• Asian Pacific Journal of Cancer Prevention
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• 제16권17호
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• pp.7837-7841
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• 2015

Objective: To assess the safety of Liena polypeptide injection (produced by JILIN FSENS PHARMACEUTICAL CO.,LTD) combined with chemotherapy in treating patients with advanced cancers. Method: A consecutive cohort of patients with advanced cancers were treated with Liena polypeptide injection combined with chemotherapy. And chemotherapy for patients with advanced cancers were adopted from regimens suggested by NCCN guideline. Liena polypeptide injection was intravenously injected at a dosage of 2ml plus 100ml normal saline for continuous 7 days during chemotherapy as one course. After at least two courses of treatment, safety and side effects were evaluated. Results: There were 20 female and 14 male patients with advanced cancer recruited into this study, including 10 patients with breast, 8 patients with colorectal, 8 patients with lung, 4 patients with gastric, and 1 patient with esophageal cancer, as well as 1 patient with non-Hodgkin's lymphoma, 1 patient with low pharyngeal and 1 patient with urethral cancer. The median age of patients was 59 (40-82) years. Incidences of Grade 1 to 2 myelosuppression was observed in 5/34 patients, and Grade 1 to 2 elevation of hepatic enzyme was recorded in 3/34 patients. Adverse effects on the gastrointestinal tract were documented in 5/34 patients, and were Grade 1. No Grade 3-4 toxicities were diagnosed. No treatment related death was found. Conclusions: Liena polypeptide injection combined with chemotherapy was safe in treating several sites of tumors, that mainly included lung, colorectal and breast cancer. However, further study should be conducted to clarify the effectiveness of this treatment.

• 대한한의학회지
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• 제35권4호
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• pp.98-103
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• 2014

Objectives: Advanced malignant melanoma (MM) has a poor prognosis, with an expected 2-year survival rate of 10 to 20%. It has long been recognized as an immunogenic tumor, and is worse for elderly patients. Many studies have suggested that herbal treatments improve immune functions, but few clinical studies have reported on this topic. Patients and History: We present two cases of female patients (72 and 77 years old, respectively) with advanced MM. The 72-year-old female patient was, at first, diagnosed with MM with multiple bone metastases. She received resection of the primary lesion, but refused further chemotherapy. The 77-year-old female patient was diagnosed with cutaneous MM of the left heel, with suspicion of sentinel node lymphadenopathy; however, she also refused any conventional treatment due to old age. Course of Therapy and Results: Both patients were exclusively treated with standardized allergen-removed Rhus verniciflua stokes (aRVS) extract combined with Bojungikki-tang (BT, Bu-Zhong-Yi-Qi-Tang in Chinese or Hochu-ekki-to in Japanese). Both patients are still alive and doing well (Feb. 2014), demonstrating that the 72-year-old patient has lived for 27 months and the 77-year-old patient has lived for 31 months without disease progression since the aRVS and BT administration. Conclusion: We suggest that the combination of aRVS extract and BT could be a candidate for overcoming the cancer's immunoediting process especially for elderly MM patients intolerant of conventional treatment.

• 품질경영학회지
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• 제42권3호
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• pp.373-386
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• 2014

Purpose: This paper seeks to analyze the relationship between project sponsor roles and project manager competencies which may account for project performance quality. Methods: After an extensive literature review, the structural equation modeling was conducted test the research model. The data was collected from project manager training course attendees by the questionnaire. Results: The results of structural equation modeling show that project sponsor roles effect on project manager competencies. Project manager competencies have a positive effect on project performance quality. Conclusion: The authors demonstrate that project sponsor external roles are related positively to project performance quality. And project manager professionalism has a positive effect on project manager communication. A number of significant findings are reported including the empirical verification that project sponsor roles, and project manager competencies may all be directly related to project performance quality.