• Bulletin of the Korean Chemical Society
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• v.35 no.8
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• pp.2375-2380
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• 2014

In the present investigation, a series of some novel 1,3-diaryl/heteroarylprop-2-en-1-one derivatives (3a-j) have been synthesized and evaluated for their in vitro cytotoxicity against three cancer cell lines, two hepatocarcinoma cell lines HUH-7, Hep-3b and one leukemia cancer cell line MOLT-4. Based on these results, structure-activity relationship (SAR) was studied on modification of $R^1$ and $R^2$ to identify the compound with maximum potency. Amongst the compounds, 3b and 3d strongly inhibited the growth of Hep-3b and MOLT-4 cells with $IC_{50}$ value of 3.39 and $3.63{\mu}M$ respectively. The results obtained from the inhibitory study had further been supported by the reactive oxygen species (ROS) measurement using flow cytometry in MOLT-4 cells. These observations collectively reveal that compounds comprising 1,3-diarylprop-2-en-1-one framework with pyrazole ring at position-3 and heteroaryl/aryl substituents at position-1 can be used as promising anticancer agents.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2006.04a
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• pp.119-124
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• 2006

The world which based on knowledge and information is changing significantly. In the various knowledge and information, the importance of GSIS has increased for efficient application and management of country. The Geomatics has made a change rapidly, observation methods have improved too. The existing acquisition of Geoinformation depend on aerial photogtaphs, but new technology Jike application of high resolution satellite images. SAR and LiDAR, is the fastest. especially, LiDAR surveying is most advanced active observation technology and Geoinfomtation is acquired by reflection of its laser pulse. In this study. the position accuracy of extracted building from LiDAR was evaluated by GPS surveying, then each data was made comparison between LiDAR's and GPS's data. After processing. the result of this study will be suggested basic data about application.

• Journal of Advanced Navigation Technology
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• v.27 no.4
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• pp.473-480
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• 2023

This study evaluated a novel method of defining the automatic flight path of unmanned aerial vehicles (UAVs) for search and rescue missions in a VR environment. The developed VR content reserves miniature digital twins of a building in the fire and a steep mountain terrain site. The users drow the UAV's scanning path using hand gestures on the surface of digital twins, and then the UAV make an automatic flight along the defined path. According to human-in-the-loop simulation tests comparing the novel method with a conventional manual flight task with 19 participants, the novel method did not improve the mission performance but participants felt a lower mental workload. The designer may need to consider the automation support on the vulnerable points of the SAR mission environment while maintaining experts' mapping capability.

• Journal of Advanced Navigation Technology
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• v.6 no.2
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• pp.97-103
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• 2002

A recent technology trends in synthetic aperture radar(SAR) requires the ultra high resolution performance in detecting and precisely identifying the targets. In this paper, as a technique for enhancing the radar range resolution, the wide band chirp connection algorithm is presented by stitching the several chirp modules with unit bandwidth based on the linear frequency modulated chirp signal waveform. The principles of the digital chirp signal generation and its architecture for implementation is described with the wide band chirp signal generator, modulator, and demodulator. The performance analysis for the presented algorithm is given with the simulation results.

• Journal of Advanced Navigation Technology
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• v.10 no.4
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• pp.377-384
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• 2006

In this paper the detection time of the distress signal for the satellite-based search and rescue (SAR) system is evaluated. Present LEOSAR system in operation employs a few Low-altitude Earth Orbit (LEO) satellites and hence provides poor and local coverage availability. This results in a considerably long waiting time for a distress beacon to be detected by a rescue mission control center. One can expect that the detection time of the distress signal will be significantly reduced if the proposed MEOSAR system, which is based on the Medium-altitude Earth Orbit (MEO) satellites, is implemented. Taking into account the influence of the obstacles on the beacon signal, simulations are carried out to evaluate the detection time of distress signals for the LEOSAR and MEOSAR systems and the corresponding results are analyzed.

• Journal of Plant Biotechnology
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• v.43 no.3
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• pp.281-292
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• 2016

Plants can recognize and respond in various ways to diverse environmental stresses, including pathogenic microorganisms, salt, drought, and low temperature. Salicylic acid (SA) is one phytohormone that plays important roles in the regulation of plant growth and development. Nonexpressor of pathogenesis-related genes 1 (NPR1) was originally identified as a core protein that could function as a transcriptional co-regulator and SA receptor during systemic acquired resistance (SAR), a plant immune response that could activate PR genes after pre-exposure of a pathogen. Although the function of NPR1 in plant defense response and the role of SA hormone in the regulation of plant physiological processes have been well characterized, the biological role of NPR1 in plant abiotic stress responses is largely unknown. In this review, we will summarize and discuss the current understanding of NPR1 function in response to plant environmental stresses.

• Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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• v.2 no.3
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• pp.155-164
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• 2004

Advanced spent fuel Conditioning Process(ACP) project which is under development for efficient spent fuel management has finished process feasibility study and is preparing $\alpha$-${\gamma}$ type hot cell construction for process experimentation. Radiation dose evaluation for the radioactive nuclides were preliminarily performed for normal operation and accident case with the basic concept design report, the meteorological data and the recent site specific data. According to the production and release rate of nuclides, dose evaluations for residents around facility were performed. The evaluation result shows a safe margin for regulation limits and SAR(Safety Analysis Report) limit of IMEF(Irradiated Material Examination Facility) where this facility will be constructed.

• Ocean and Polar Research
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• v.33 no.1
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• pp.1-11
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• 2011

This study describes measurements of fast ice recorded on May 23, 2009, in Kongsfjorden (translated as 'Kongs Fjord'), an inlet on the west coast of Spitsbergen in the Svalbard Archipelago. Seasonal fast ice is an important feature for Svalbard fjords, both in relation to their physical environment and also the local ecosystem, since it grows seaward from the coast and remains in place throughout the winter. Ice thickness, snow, ice properties, and wind speed were measured, while SAR (Synthetic Aperture Radar) data was observed simultaneously observed two times from ALOS-PALSAR (L-band). Measured ice thickness was about 25-35 cm while the thickness of ice floe broken from fast ice was measured as 10-15 cm. Average salinity was 1.9-2.0 ppt during the melting period. Polarimetric data was used to extract H/A/alpha-angle parameters of fast ice, ice floe, snow and glacier, which was classified into 18 classes based on these parameters. It was established that the area of fast ice represents surface scattering which indicates low and medium entropy surface scatters such as Bragg and random surfaces, while fast ice covered with snow belongs to a zone of low entropy surface scattering similar to snow-covered land surfaces. The results of this study will contribute to various interpretations of interrelationships between H/A/alpha parameters and the wave scattering Phenomenon of sea ice.

• Journal of Satellite, Information and Communications
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• v.12 no.4
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• pp.78-86
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• 2017

Japan has a lot of interest about weapons systems development of surrounding national and has invested heavily in securing intelligence assets to get information about them, because of conflict issues between Japan and Russia with four northern islands, China with Senkaku Islands and entry policy into the Pacific. Japan has used a large budget to detect and intercept ballistic missile for reasons of the launch of the Taepodong missile in 1998. After took over SIGINT equipments which U.S. force had operated in 1950s~1960s, Japan made a technological analysis and advanced IT technology to produce superior equipments. Japan's SDF has installed them in 19 locations across Japan. In addition, Japan's JASDF has installed advanced early warning RADAR to detect aircraft and high speed ballistic missile entering JADIZ with S-band in 28 locations across Japan. It is possible to detect missile launch preparations, engine tests, and launch moments at any time for operation of 6 satellites high resolution reconnaissance system and 6 aegis ships. In close cooperation with the US, Japan is accessible to the SBIRS networks which detects the launch of a ballistic missile in neighboring countries. In the future, Because the United States wants Japan to act as part of the United States in East, south Asia, it is believed that the exchange of intelligence on the surrounding countries between two countries will be enhanced.

• Journal of Satellite, Information and Communications
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• v.10 no.4
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• pp.117-127
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• 2015

Recently, research and development on satellite payloads are being developed such as the optical sensor, SAR etc. Satellite image for earth observation is being utilized both domestically and abroad. Advanced satellite payload technology has led to the collection and analysis of satellite images relying on the optical sensor. Currently, related organizations such as RDA(the Rural Development Administration) are collectively collaborating to plan a national project to develop a medium-sized satellite based on Korea's domestic technology independently. This paper investigated the cases of the past research on application of satellite images for agriculture and analyzed the technical specifications for satellite payload in each area of such application. Based on the results of the past surveys and consultation studies among local experts in satellite image application, we analyzed the current trends, plans and applications of domestic and overseas R&D in satellite payloads for earth observation in agriculture, and proposed the appropriate technical specifications for developing a future medium-sized satellite for agriculture. The proposed specifications were then incorporated into a simulated satellite to examine its performance to observe the Korean farming areas. The authors anticipate that the findings of this paper will form a useful technical basis for providing the appropriate specifications for developing future medium-sized satellite payloads to be used in agriculture and forestry, and enabling the end users to efficiently utilize the satellite.