• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6257-6261
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• 2014

Background: HPV related cervical cancer as one of the most common women cancers in developing countries. Regarding accessibility of commercial vaccines, any long or short term modality for integrating preventive immunization against HPV in a national program needs comprehensive information about HPV prevalence and its genotypes. The important role of selecting most accurate diagnostic technologies for obtaining relevant data is underlined by different assays proposed in the literature. The main objective of the present study was to introduce an in-house HPV typing assay using multiplex real time PCR with reliable results and affordable cost for molecular epidemiology surveys and diagnosis. MATERIALS AND METHODS: 112 samples of formalin fixed paraffin embedded tissues and liquid based cytology specimens from patients with known different grades of cervical dysplasia and invasive cancer, were examined by this method and the result were verified by WHO HPV LabNet proficiency program in 2013. RESULTS: HPV was detected in 105 (93.7%) out of 112 samples. The dominant types were HPV 18 (61.6%) and HPV 16 (42.9%). Among the mixed genotypes, HPV 16 and 18 in combination were seen in 12.4% of specimens. CONCLUSIONS: According to acceptable performance, easy access to primers, probes and other consumables, affordable cost per test, this method can be used as a diagnostic assay in molecular laboratories and for further planning of cervical carcinoma prevention programs.

• Asian Pacific Journal of Cancer Prevention
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• 제15권8호
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• pp.3587-3592
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• 2014

Burden of cancer is progressively increasing in developing countries like India which has also led to a steep rise in toxicity due to anti-cancer therapy. A cross-sectional analysis was here conducted for patients with different malignancies (except leukaemia) who while undergoing radical anti-cancer therapy were admitted to our oncology ward from January-July 2013. In a total of 280 patients, the total number of toxicity events was 473. Nine patients expired over this time period. Among the events, grade 2 anaemia the most common (n=189) while the most common grades of neutropenia and thrombocytopenia were grade 4 (n=114) and grade 2 (n=48), respectively. Among the tracable microbial etiologies, gram negative bacteria were the most commonly found pathogens. Treatment interruptions took place in 240 patients (median duration=8.8 days). Prolonged hospital admission, intensive care and artificial ventilation support was needed to be given in 48, 7 and 13 patients respectively. Advanced NSCLC, KPS <70, pancytopenia and artificial ventilation requirement were found to have a significant impact on death. Such studies show the prevailing practice from institutes of our country and may guide us formulating a guideline for managing such toxicities for this part of the world.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.1857-1859
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• 2016

Background: Hodgkin's lymphoma (formerly, Hodgkins disease) is a potentially curable malignancy with distinctive biological behavior and specific clinical characteristics. Limited information is available from developing countries for patients with classical Hodgkin's lymphoma (cHL). Therefore we reviewed the demographical and clinico-hematological profiles along with bone marrow infiltration patterns in adult patients presenting at Liaquat National Hospital and Medical College. Materials and Methods: In this cross sectional study, 62 adult (${\geq}15years$) patients with cHL were enrolled from January 2010 to December 2014. Results: The mean age was $29.7{\pm}13.8years$ with a median of 30 years. The male to female ratio was 2:1. B symptoms were present in 72.5% of patients and lymph node enlargement in 85.4%. The frequency of bone marrow infiltration in our cHL patients was found to be 27.4%, the pattern being predominantly focal followed by diffuse. The mean hemoglobin was $9.4{\pm}1.9g/dl$ with a mean MCV of $78.1{\pm}7.9fl$, a mean total leukocyte count of $10.9{\pm}20.6{\times}10^9/l$ and a mean platelet count of $241.6{\pm}150.1{\times}10^9/l$. Conclusions: Our analysis shows that clinico-pathological features of cHL in Pakistan are comparable to published data. Peripheral lymphodenopathy associated with B symptoms is the commonest presentation. Bone marrow involvement is more common in our setup as patients usually presented at an advanced stage of disease.

• Asian Pacific Journal of Cancer Prevention
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• 제16권3호
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• pp.1259-1275
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• 2015

Background: This study reviewed the published evidence as to how prostate cancer outcomes vary across geographical remoteness and area level disadvantage. Materials and Methods: A review of the literature published from January 1998 to January 2014 was undertaken: Medline and CINAHL databases were searched in February to May 2014. The search terms included terms of 'Prostate cancer' and 'prostatic neoplasms' coupled with 'rural health', 'urban health', 'geographic inequalities', 'spatial', 'socioeconomic', 'disadvantage', 'health literacy' or 'health service accessibility'. Outcome specific terms were 'incidence', 'mortality', 'prevalence', 'survival', 'disease progression', 'PSA testing' or 'PSA screening', 'treatment', 'treatment complications' and 'recurrence'. A further search through internet search engines was conducted to identify any additional relevant published reports. Results: 91 papers were included in the review. While patterns were sometimes contrasting, the predominate patterns were for PSA testing to be more common in urban (5 studies out of 6) and affluent areas (2 of 2), higher prostate cancer incidence in urban (12 of 22) and affluent (18 of 20), greater risk of advanced stage prostate cancer in rural (7 of 11) and disadvantaged (8 of 9), higher survival in urban (8 of 13) and affluent (16 of 18), greater access or use of definitive treatment services in urban (6 of 9) and affluent (7 of 7), and higher prostate mortality in rural (10 of 20) and disadvantaged (8 of 16) areas. Conclusions: Future studies may need to utilise a mixed methods approach, in which the quantifiable attributes of the individuals living within areas are measured along with the characteristics of the areas themselves, but importantly include a qualitative examination of the lived experience of people within those areas. These studies should be conducted across a range of international countries using consistent measures and incorporate dialogue between clinicians, epidemiologists, policy advocates and disease control specialists.

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.957-962
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• 2012

Objective: Rapidly increasing colorectal cancer (CRC) incidence in Malaysia and the introduction of cutting edge new treatments, which prolong survival, mean that treatment outcome measures meed to be evaluated, including consideration of patient's quality of life (QoL) assessment. There are limited data on QoL in CRC patients, especially in Malaysia. Therefore, this study was performed focusing on cancer stages and age groups. Methods: The cross sectional study was conducted from June to September 2011 at three public tertiary hospitals with the EORTC QLQ C-30 questionnaire in addition to face to face interview and review of medical records of 100 respondents. Results: The mean age was 57.3 (SD 11.9) years with 56.0% are males and 44.0% females, 62% of Malay ethnicity, 30% Chinese, 7% Indian and 1% Sikh. Majority were educated up to secondary level (42%) and 90% respondents had CRC stages III and IV. Mean global health status (GHS) score was 79.1 (SD 21.4). Mean scores for functional status (physical, emotional, role, cognitive, social) rangeds between 79.5 (SD 26.6) to 92.2 (SD 13.7). Mean symptom scores (fatigue, pain, nausea/vomiting, constipation, diarrhea, insomnia, dyspnoea, loss of appetite) ranged between 4.00 (SD 8.58) to 20.7 (SD 30.6). Respondents role function significantly deteriorates with increasing stage of the disease (p=0.044). Females had worse symptoms of pain (p=0.022), fatigue (p=0.031) and dyspnoea (p=0.031). Mean insomnia (p=0.006) and diarrhea (p=0.024) demonstrated significant differences between age groups. Conclusion: QOL in CRC patients in this study was comparable to that in other studies done in developed countries. Pain, fatigue and dyspnoea are worse among female CRC patients. Given that functions deteriorates with advanced stage of the disease at diagnosis, a systematic screening programme to detect cases as early as possible is essential nationwide.

• 무역학회지
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• 제41권4호
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• pp.293-313
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• 2016

동아시아 지역은 FTA 확대로 인해 국경을 초월한 경제일체화가 진척되고 있고, 각국의 규제제도 개혁으로 기업활동의 자유는 높아지고 있으며, 국경을 초월한 공정간 분업이 진전되고 있는 등 무역네트워크의 고도화가 촉진되고 있다. 미국이 주도하는 다자간 FTA인 환태평양경제동반자협정(TPP)은 2016년 2월 4일 뉴질랜드 오클랜드에서 12개국이 협정문에 서명하였는데, 동아시아 무역네트워크의 변화가 예상된다. 본 연구에서는 TPP가 동아시아 무역네트워크에 미칠 영향에 관해 살펴보았다. 연구결과 TPP는 공급사슬의 글로벌화를 이끄는 규제 및 제도로써 공급사슬 구조를 변화시키고, 가치사슬에 긍정적인 효과를 야기한다. 이는 동아시아 무역네트워크에 상당한 영향을 미칠 것이며 참여기업의 경쟁력 강화로 이어질 것이다. 또한 TPP는 향후 아태자유무역지대(FTAAP)의 실현을 위한 토대가 될 것으로 보이는데, 무역의존도가 높은 한국은 이로 인해 변화할 동아시아 무역환경에 효과적으로 대처하기 위한 정책적 노력을 기울여야 할 것이다.

• 한국지역지리학회지
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• 제17권1호
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• pp.17-39
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• 2011

최근 상대적으로 경제가 발전한 동북아 국가들로 외국인 이주자들의 유입이 급증하고 있으며, 특히 일본은 이에 따른 다문화사회로의 전환에 대처하기 위하여 '다문화공생'을 외국인 이주자 관련 담론과 정책의 핵심적 개념으로 사용하고 있다. 이 논문은 우선 한국이나 일본이 겪고 있는 다문화사회의 유형이 서구의 경우와는 다르다는 점을 보이기 위해 다문화사회의 유형 구분을 제시한다. 그리고 한 국가 내에서도 외국인 이주자들은 유형에 따라 상이한 특성을 가지며, 일본 문화와의 결합 정도도 차별적임음 강조한다. 이러한 다문화사회로의 전환은 사회적 과정일 뿐만 아니라 동시에 지리적 과정으로 전개되며, 또한 지역별로 다르게 진행되고 특히 외국인 이주자들의 출신과 유입 유형에 따른 지역별 분화를 동반한다. 다문화사회로의 전환의 사회공간적 과정을 일정하게 통제하고자 하는 일본의 다문화공생 정책은 서구에서 발달한 다문화주의를 원용하여 외국인 이주자들과 일본인들 간의 공생을 위해 지역사회가 주도하는 정책이라는 점에서 의의를 가지지만, 대체로 일계인(日系人)의 유입이 많은 지자체들에서 우선적으로 전개되면서 주로 문화적 측면을 강조하며, 결국 외국인 이주자 통제 전략의 성격을 내포하고 있는 것으로 평가된다. 이념적으로 일본의 다문화공생 개념은 '기회 평등'으로서의 '자유주의적 다문화주의'와 가깝고 '결과 평등'으로서의 '조합주의적 다문화주의'와는 거리가 먼 것으로 이해된다. 또한 진정한 다문화주의 실현을 위한 단계별 진행에서 보면, 이 개념의 실제 실행은 관용의 단계에서 비차별의 법제화 단계로 나아가 가는 과정에 있으며 아직 인정을 위한 사회적 패러다임화되지 않음으로써 보수적 정권이 등장할 경우 동화주의로 쉽게 퇴행할 가능성을 가지는 것으로 추정된다.

• The Journal of Asian Finance, Economics and Business
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• 제7권9호
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• pp.719-726
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• 2020

Education policy is a dynamic process featuring social development trends. The world countries have focused their education program on empowering the learners for future life and work. This paper aims to assess the higher education curriculum based on a survey of 280 students, employers, alumni, and lecturers in both social sciences and natural sciences in Ho Chi Minh City, Vietnam. The fuzzy decision-making method, namely the Fuzzy Extent Analysis Method (F-EAM), was applied to measure the relative weight of each parameter. Seven factors under the curriculum development have been put in the ranking. Input with emphasis on foreign language was the highest priority in curriculum development, given the expected demand of the labor market. Objective and learning outcome and teaching activities ranked second and third, respectively. The traditional triangle of teaching content, methodology, and evaluation and assessment are still proven their roles, but certain modifications have been defined in the advanced curriculum. Teaching facilities had the least weight among the seven dimensions of curriculum development. The findings are helpful for education managers to efficiently allocate scarce resources to reform the curriculum to bridge the undergraduate quality gap between labor supply and demand, meeting the dynamic trends of social development.

• 디지털융복합연구
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• 제16권7호
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• pp.401-408
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• 2018

지난 몇 년간, 한국 관광객의 국제 관광지 유입은 특히 아시아가 아닌 국가에서 크게 증가했다. 그러나 멕시코는 여전히 한국 관광객에게 인기있는 관광지가 아니다. 이러한 현상의 제고와 인식의 개선을 위해 본 연구를 진행하였다. 이 논문은 켈러의 브랜드 에퀴티 모델을 사용하여 한국인과 멕시코인이 가지는 일반적인 브랜드 이미지를 비교하고 분석하였다. 한국 관광객이 멕시코라는 나라에 가지는 국가 브랜드와 관광지로서의 수준을 파악하여 연구의 가치를 더하였다. 이 연구의 결과는 후속적으로 이루어질 멕시코의 국가 브랜드 홍보를 위한 새로운 접근법이 될 것이며, 기획, 창작, 디자인 및 개발 연구에 가치있는 초석이 될 것이다.

• Journal of Korea Trade
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• 제25권4호
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• pp.146-163
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• 2021

Purpose - This paper examines China's impact on Korea's ICT exports considering the direct competition channel, the production shift channel, and the indirect demand channel at once. This paper also takes China's economic rebalancing into account and discusses whether it makes any differences in the effect of the three channels. Design/methodology - To quantify the effect of the three channels, I constructed a linear panel regression model and estimated it with various estimation methods including the system GMM. China's exports toward the same destination as Korea's exports, Korea's exports toward China, and the third countries' exports toward China respectively reflect the three channels. China's GVC indicators are included as well to evaluate the effect of further China's economic rebalancing. Since the present paper has a greater interest in the effect of China rather than the determinant of bilateral trade, a (fixed effect) panel model becomes more appropriate than the gravity model because timeinvariant variables in the gravity model, such as the distance and the language, are eliminated during the estimation process. Findings - The estimation results indicate that Chinese ICT exports are complementary to Korea's ICT exports in general. However, when markets are considered in subgroups, China's ICT exports could have a negative effect in the long run, especially for SITC75 and SITC76 markets, implying a possible competitive threat of China. The production shift effect turns significant during China's economic rebalancing in the markets for the advanced economies and the SITC76 product. China's indirect demand channel is also in effect significantly for the advanced economy and SITC75 commodities during China's economic rebalancing periods. In addition, this paper shows that China's transition toward upstream in the global value chain could have a positive impact on Korea's ICT exports, especially at the Asian market. Originality/value - The contribution of this paper is threefold. First, it focuses on the ICT industry for which Korea increasingly depends on China and China becomes a global hub of the GVC. Second, this paper quantitatively studies three channels in a model in contrast to the literature which mostly examines those channels separately and pays less attention to the GVC aspect. Third, by utilizing relatively recent data from the period of 2001-2017, this paper discusses whether China's economic rebalancing affects the three channels.