• Title/Summary/Keyword: Adult disease.

Search Result 1,311, Processing Time 0.033 seconds

Differential Expression of Hox and Notch Genes in Larval and Adult Stages of Echinococcus granulosus

  • Dezaki, Ebrahim Saedi;Yaghoobi, Mohammad Mehdi;Taheri, Elham;Almani, Pooya Ghaseminejad;Tohidi, Farideh;Gottstein, Bruno;Harandi, Majid Fasihi
    • Parasites, Hosts and Diseases
    • /
    • v.54 no.5
    • /
    • pp.653-658
    • /
    • 2016
  • This investigation aimed to evaluate the differential expression of HoxB7 and notch genes in different developmental stages of Echinococcus granulosus sensu stricto. The expression of HoxB7 gene was observed at all developmental stages. Nevertheless, significant fold differences in the expression level was documented in the juvenile worm with 3 or more proglottids, the germinal layer from infected sheep, and the adult worm from an experimentally infected dog. The notch gene was expressed at all developmental stages of E. granulosus; however, the fold difference was significantly increased at the microcysts in monophasic culture medium and the germinal layer of infected sheep in comparison with other stages. The findings demonstrated that the 2 aforementioned genes evaluated in the present study were differentially expressed at different developmental stages of the parasite and may contribute to some important biological processes of E. granulosus.

The simulator loop probe style magnetic stimulation design for a nervous system treatment (신경계 치료를 위한 루프 프로브형 자기자극기의 시뮬레이터)

  • Kim, Whi Young
    • Journal of Korea Society of Digital Industry and Information Management
    • /
    • v.5 no.3
    • /
    • pp.29-37
    • /
    • 2009
  • It is as result that study to apply mini magnet nerve curer in peripheral nervous system disease treatment. Simulator and embodied action power and Control Unit in cylinder form of magnet roof object firstly. Yielded service area about special quality of probe of loop object cylinder style and treatment area dimension and distance of treatment pulse secondly. Embody pulse forming course energy value by Probe's form by third, could embody treatment pulse by disease. Specially, through a special quality experiment, saved Damping pulse form and treatment digital forming etc. variously. Lately, embodied this to aid a little in disease treatment that follow that there is no invasion that there is no stimulation by medicine development. Neuralgia, muscular disease and Altzheimer, with stroke etc. is becoming the matter of concern and interest which disease of adult etc. it is same is important. And the melancholia in compliance with the modern direction of a ceremony which is complicated and garrulous, trillion it will cry and symptoms, it is a tendency where the emotional obstacle etc. nervous psychiatric disorder patient is increasing at class speed. But currently the applicator it will be able to treat like this disease almost it is a condition which is wholly lacking. Consequently like this disease it used magnetic stimulation and it diagnosed and the equipment it will be able to treat plan and it embodied.

Ectopic migration of Dirofilaria immitis in a Eurasian otter (Lutra lutra) in Korea

  • Jung, Ji-Youl;Lee, Kyunghyun;Seo, Hyun-Ji;Cho, Yun Sang;Kim, Young-Dae;Kim, Ji-Hyeon;So, ByungJae;Choi, Eun-Jin
    • Korean Journal of Veterinary Research
    • /
    • v.58 no.2
    • /
    • pp.107-109
    • /
    • 2018
  • An 8-year-old female Eurasian otter (Lutra lutra) reared in a wetland center, died 2 h after sudden onset of astasia and dyspnea despite medical treatment. Gross examination of internal organs revealed 10 adult filarioid nematodes in the right ventricle of the heart and three between the left and right cerebral hemispheres. All nematodes were identified as Dirofilaria immitis by direct microscopy and polymerase chain reaction assay. Histopathological observation revealed multifocal hemorrhage in the cerebral subarachnoid space and focal necrosis with hemorrhage in the cerebellar parenchyma. Although rare, veterinarians should consider cerebral dirofilariasis as a differential diagnosis in unexplained neurological cases.

HISTIOCYTOSIS X (조직구 증식증 X)

  • Chun, Hye-Kyung;Oh, Seong-Seob;Kim, Il-Gyu;No, Sang-Yeob
    • Maxillofacial Plastic and Reconstructive Surgery
    • /
    • v.18 no.4
    • /
    • pp.718-725
    • /
    • 1996
  • Histiocytosis X is the abnormal proliferation of histiocytes and usually a massive aggregation of eosinophilic leukocytes. The clinical features and prognosises of subclasses of histiocytosis X depend on the severity and extent of the organ involvement. The subclasses include Letterer-Siwe disease(Acute disseminated histiocytosis X), eosinophilic granuloma, Hand-Schuller-Christian disease. Letterer-Siwe disease(acute, subacute form) refers to the form of disease that is most often fatal because of the widespread skeletal, extraskeletal lesion ; this usually affects infants and children less than 3 years of age. Eosinophilic granuloma(histiocytosis X, localized) refers to a chronic form of disease with skeletal lesion ; It usually affects children and young adult. Hand-Schuller-Christian disease(chronic form) refers to a chronic form of disease with skeletal, extraskeletal lesions. It usually affects children over the age of 3 years. In our hospital, 8 year old female patient visited complaining of hard swelling of mandibule body, left side and 6 year old female patient visited complaining of painful swelling of mandibular angle, right side. We diagnosed eosinophilic granuloma and curetted the lesiones and refered to Dept. pediatrics for chemotherapy. We present 2 cases to you with literatures.

  • PDF

CABG for an Adult with Coronary Disease due to Kawasaki Disease (성인기 가와사키병에 합병된 관상동맥 질환에서의 관상동맥 우회술)

  • Song, Hyun;Kim, Sang-Pil;Ryu, Sang-Wan
    • Journal of Chest Surgery
    • /
    • v.32 no.9
    • /
    • pp.831-834
    • /
    • 1999
  • The Kawasaki disease has been reported worldwide since the first description in 1967 in Japan. Approximately 20% of the children with untreated Kawasaki disease are believed to develop coronary artery aneurysm of which 2-3% progress to coronary artery stenosis. The Kawasaki disease rarely affects adults and accordingly, there have been only a few cases reported in literatures. The present case describes a successful surgical treatment of a 43-year-old female patient with coronary artery aneurysm and stenosis, which resulted from an episode of the Kawasaki disease that occurred 20 years earlier. The patient was well at 5 months followup.

  • PDF

The effects of dietary protein intake and quality on periodontal disease in Korean adults (한국 성인의 단백질 섭취량과 식생활의 질이 치주질환에 미치는 영향)

  • Hwang, Su-Yeon;Park, Jung-Eun
    • Journal of Korean society of Dental Hygiene
    • /
    • v.22 no.2
    • /
    • pp.107-115
    • /
    • 2022
  • Objectives: This study aimed to examine the effects of dietary protein intake and quality on periodontal disease in Korean adults. Methods: The data used for analysis were obtained from the 7th Korean National Health and Nutrition Examination Survey (2016-2018). Data were analyzed using chi-square and t-test. Additionally, multiple logistic regression analysis was performed to assess the association between dietary protein intake and quality and periodontal disease. Statistical significance level was set at <0.05. Results: Multiple logistic regression analysis of dietary protein intake and periodontal disease in the model adjusted for socioeconomic factors showed that were significantly related to the Q1 (odds ratio [OR]: 1.18, 95% confidence interval [CI]: 1.01-1.39). However, this correlation was not significant in the model in which all variables were corrected. Moreover, analysis of the dietary protein quality and periodontal disease in model 4, which was adjusted for socioeconomic variables, showed that were significantly related to the low score (OR: 1.13, 95% CI: 1.00-1.27). Conclusions: The results showed a significant association between periodontal disease and poor intake and quality of dietary protein in the Korean adult population.

Clinical Outcome of Ureteropelvic Junction Obstruction in the Pediatric and Adult Population (소아와 성인에서의 신우요관이행부폐색의 임상적 경과)

  • Song, Phill-Hyun;Kwon, Sang-Taek;Yeo, Ji-Hyun;Park, Yong-Hoon;Moon, Ki-Hak
    • Journal of Yeungnam Medical Science
    • /
    • v.21 no.1
    • /
    • pp.67-73
    • /
    • 2004
  • Background: A ureteropelvic junction (UPJ) obstruction is a congenital anomaly commonly afflicting the pediatric population. However, it occurs more frequently in adults than is generally appreciated. To assess their characteristics, we have here compared and analyzed the clinical manifestations, causes, and outcomes of UPJ obstruction found in children and adults. Materials and Methods: 102 patients (118 renal units) out of 182 patients (218 renal units), with diagnosed UPJ obstruction, were available for follow up. The follow-ups were retrospectively reviewed to determine the presenting symptoms, treatments, and clinical outcomes. Patients who were younger than 18 years of age were assigned to the pediatric group (44 patients), others the adult group (58 patents). Results: The majority of the patients presented with flank pain (pediatric group: 68%, adult group: 76%). The majority of patients underwent a pyeloplasty (pediatric group: 50.9%, adult group: 62.3%). And the major cause of the UPJ obstruction was an intrinsic stenosis (pediatric group: 53%, adult group: 56%). Conclusion: The prevalence of bilateral UPJ obstruction in adults is evidently less prevalent than in pediatrics, and despite the late diagnosis, the surgical outcome is similar. A further investigation of UPJ obstruction will lead us to a more comprehensive understanding of the disease.

  • PDF

Echocardiography of heartworm disease in Jindo dogs (진도개에 감염된 심장사상층증의 초음파 진단에 관한 연구)

  • Shin, Sung-shik;Kwon, Jung-kee;Kim, Sang-ki
    • Korean Journal of Veterinary Research
    • /
    • v.40 no.4
    • /
    • pp.729-739
    • /
    • 2000
  • Echocardiography, vital signs, microfilaremia, and blood chemistry of 12 Jindo dogs naturally infected with canine heartworms (Dirofilaria immitis) were analysed and compared with those of 5 uninfected control Jindo dogs. Nine of the twelve infected dogs contained microfiaria in the peripheral blood, whereas the presence of adult heartworms in the pulmonary arteries and/or in the heart was detected from four dogs by echocardiography. Among the four echocardiography-positive dogs, two dogs also displayed evidence of heartworms in the right ventricle by echocardiography. Upon necropsy, a total of 547 adult worms was collected from the 12 infected dogs (av = 45.6, range = 9-166). Dogs with positive echocardiograpic images of heartworms contained 48, 74, 104 and 166 adult worms in the heart, pulmonary arteries and/or in the caudal vena cava (av. 98.0), whereas 9 to 39 worms (av. 19.4) were collected from those organs of dogs with negative echocardiography. Most heartworms were found in the right ventricle (438, 80%) at necropsy, whereas relatively fewer worms were found in the pulmonary arteries (96, 17.6%), and in the caudal vena cava (13, 2.4%). The necropsy findings on the location of adult worms significantly differed from the results of echocardiographic analysis in which the right ventricle of most dogs did not show the presence of heartworms. These results indicated that the adult heartworms had been located in the terminal branches of the pulmonary arteries when the host was alive, but the worms moved toward the right ventricle shortly after the heart of the infected dogs stopped beating. Microfilaremia in the peripheral blood was the highest in the blood samples collected at 10 pm. However, the correlation between the number of microfilaria and of adult worms was not observed. Clinical and vital signs of infected dogs did not show any significant difference before and after a 30 minute-exercise at 5 km/hr compared to those of uninfected control dogs.

  • PDF