• Childhood Kidney Diseases
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• 제24권2호
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• pp.91-97
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• 2020

Purpose: Alport syndrome (AS) is one of the most common inherited renal diseases caused due to mutations of genes encoding specific proteins of the type IV collagen family, and its major clinical manifestations include progressive renal failure, sensorineural deafness, and ocular abnormalities. We investigated the clinical characteristics and long-term prognosis of AS in Korean pediatric and adult populations. Methods: We conducted a retrospective review of medical records of 33 children and adults who had been diagnosed or treated with AS from 1985 to 2019. Results: The mean age of the 33 patients diagnosed with AS was 16.2±13.6 years, and the male-to-female ratio was 2:1. At the first visit, recurrent gross hematuria was the most common initial symptom. In 10 of 33 patients (30.3%), sensorineural hearing loss (SNHL) was diagnosed, but none had ophthalmic problems. Moreover, 11 of 33 patients (33.3%) had advanced to end-stage renal disease (ESRD), and a significant difference was observed in the age of the patients who progressed to ESRD based on the presence or absence of SNHL (P=0.035). Conclusion: SNHL in AS can be an important prognostic factor for long-term deterioration of renal function. Further investigation is required to confirm the clinical course and the genetic characteristics of AS in Korea through prospective national cohort studies.

• Nutrition Research and Practice
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• 제11권4호
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• pp.300-306
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• 2017

BACKGROUND/OBJECTIVES: The doubly labeled water (DLW) method is considered the gold standard for the measurement of total energy expenditure (TEE), which serves to estimate energy requirements. This study evaluated the accuracy of predictive dietary reference intake (DRI) equations for determining the estimated energy requirements (EER) of Korean adults by using the DLW as a reference method. SUBJECTS/METHODS: Seventy-one participants (35 men and 36 women) aged between 20 and 49 years were included in the study. The subjects' EER, calculated by using the DRI equation ($EER_{DRI}$), was compared with their TEE measured by the DLW method ($TEE_{DLW}$). RESULTS: The DRI equations for EER underestimated TEE by -36.3 kcal/day (-1.3%) in men and -104.5 kcal/day (-4.9%) in women. The percentages of accurate predictions among subjects were 77.1% in men and 62.9% in women. There was a strong linear correlation between $EER_{DRI}$ and $TEE_{DLW}$ (r = 0.783, P < 0.001 in men and r = 0.810, P < 0.001 in women). CONCLUSIONS: The present study supports the use of DRI prediction equations to determine EER in Korean adults. More studies are needed to confirm our results and to assess the validity of these equations in other population groups, including children, adolescents, and older adults.

• Preventive Nutrition and Food Science
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• 제3권2호
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• pp.186-192
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• 1998

This study was conducted to investigate the relationship among prevalence of obesity, nutritional status and factors related to obesity of women who exercise regularly. The subjects of this study were 100 women who have been exercising regularly for more than 6 months. They were mostly housewives ages 24 to 63 years and had graduated middle or high school. Their average income was form 700 to 1,500 thousand won per month and most of them had 2 r 3 children. They sleep usually 6~8 hours a day. Most of physical indices of obesity were increased progressively with age. Among them , weight (61.5$\pm$1.4kg), subscapular (16.3$\pm$1.4mm) and abdomen(31.4$\pm$1.2mm) skinfold thickness were higher in 50 years than in others. BMI after exericse was decreased compared with BMI before exericise. WHR was 0.82 in 40 years and 0.85$\pm$0.01 in 50- to 60- year-old group. The percentage of body fat increased with advancing years and the highest values were shown in 50 - to 60-year old group (skyndex value : 38.6$\pm$0.6, BIA value : 28.7$\pm$0.8<0.05). The prevalence of obesity was measured by bioelectrical impedance fatness analyzer (BIA), obdy mass index (BMI) and skinfold thickness were 17.0%, 24.0% and 78.0% respectively. Most subjects were in good nutritional status, but in the subjects aged 24~49, energy (89.3%), iron (93.3%) and vit. A (97.4%) intake were slighltyl lower than the RDA. Energy intake was slightly insufficient tot he 50-63year old subjects (88.6%) compared with RDA. It seemed that they restricted calorie intake for the weight control. The energy percentage of carbohydrate, fat and protein was 65 : 20 : 15, the result of which came closed to the recommended calorei composition. There were positive correlations between obesity and other variable such as age. number of childeren and physical indics.

• 한국가족관계학회지
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• 제21권4호
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• pp.3-25
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• 2017

Objectives: We examined which socioeconomic and intergenerational characteristics were associated with the level of intention to marry among Korean men and women in young adulthood. Method: Data came from 351 men and 391 women who were 25-34 years old, had never been married, and had at least one living parent. We conducted multiple regression analyses by gender after controlling for age and current romantic relationship. Results: Among the socioeconomic characteristics, more years of education was linked to both men's and women's higher levels of intention to marry. For women, having a secure, full-time job was related to greater intention to marry. For men, the higher their subjective socioeconomic status, the greater their intention to marry. Among intergenerational characteristics, both men's and women's positive attitudes toward supporting elderly parents were related to a higher level of intention to marry. For men, the frequency of providing instrumental support for their parents was negatively associated with the men's intention to marry. For women, higher levels of agreement with parents' responsibility to support their adult children as well as greater affection for their parents were positively related to greater intention to marry. Conclusions: The findings suggest that young adults' socioeconomic resources and the family context are important predictors of young adults' marital intentions. The results also reveal gender differences in the factors associated with young adults' marital intentions.

• 한국가족관계학회지
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• 제21권3호
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• pp.3-23
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• 2016

Objectives: The purpose of this study is to examine the effects of symptoms of dementia elderly on the primary caregiver's depression. In addition, moderating effect of family support was examined. Based on the results, the necessity for intervention in the level of social welfare as a way to mitigate primary caregiver's depression was suggested. Method: In order to accomplish these purposes, a total of 197 who are spouse and adult-children of dementia elderly using day care facilities or services in Seoul, Gyeonggi, Busan province, South Korea were utilized. Data were analyzed by frequency analysis and descriptive statistics, regression model analysis with SPSS 18.0. Results: In case of analysis results, the mean value was reported 0.9 out of four point about primary caregiver's depression and the mean value of family support was reported 3.34 out of five point. And besides, the analysis result of dementia elderly's symptoms showed that prevalence of depression/dysphoria were 62.2%, prevalence of aberrant motor were 61.3%, prevalence of apathy/indifference were 56.6%. Crucial findings are as follows: the symptoms of dementia elderly was significantly associated with the primary caregiver's depression. At the same time, family support significantly influenced lower level of the primary caregiver's depression. While, in the relationship between the symptoms of dementia elderly and the primary caregiver's depression, family support has a moderation effect by important protection factor. Conclusions: From these findings, the necessities to provide the care service for dementia elderly to help improve symptoms of dementia as well as the policy and service to manage the mental health of the family as primary caregiver were suggested. Also, the necessities to provide the family therapy program to improve the relationship with family members were suggested.

• 대한방사선기술학회지:방사선기술과학
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• 제44권3호
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• pp.195-203
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• 2021

Although intra oral dental x-ray is a lower dose than other radiological examinations, pediatric patients are known to have a higher risk of radiation damage than adults. For this reason, pediatric dental x-ray requires management of dose evaluation and imaging conditions during the examination. In this study, the dose calculation program ALARA-Dental(child/adult) was used to evaluate the organ dose and effective dose exposed to each examination site during intra oral imaging of children during dental radiographic examination, and dose analysis according to the imaging conditions was performed. As a result, the highest organ dose distribution was shown at 0.044 ~ 0.097 mGy in all are as of the mucous membrane of oral cavity except for the maxillary incisors and canines. Also, in the case of the thyroid gland, the maxillary canine and maxillary premolar examination showed 0.027 and 0.020 mGy, respectively, and the dose distribution was 15.4% to 70.0% higher than that of the mandibular examination. As for the effective dose calculated during intra oral imaging, the maxillary anterior and canine examinations showed the highest effective doses of 0.005 and 0.004 mSv, respectively, and the maxillary area examination showed a higher dose distribution on average than the mandible.

• Journal of Radiation Protection and Research
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• 제46권4호
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• pp.170-177
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• 2021

Background: The International Commission on Radiological Protection is preparing to provide reference dose coefficients for environmental radioiodine intake based on newly developed age-specific biokinetic models. However, the biokinetics of iodine has been reported to be strongly dependent on the dietary intake of stable iodine; for example, the thyroidal uptake of iodine may be substantially lower in iodine-rich regions than in iodine-deficient regions. Therefore, this study attempted to establish a system of age-specific thyroid dose estimation for South Koreans, whose daily iodine intakes are significantly higher than that of the world population. Materials and Methods: Korean age-specific biokinetic parameters and thyroid masses were derived based on the previously developed Korean adult model and the Korean anatomical reference data for adults, respectively. This study complied with the principles used in the development of age-specific biokinetic models for world population and used the ratios of baseline values for each age group relative to the value for adults to derive age-specific values. Results and Discussion: Biokinetic model predictions based on the Korean age-specific parameters showed significant differences in iodine behaviors in the body compared to those predicted using the model for the world population. In particular, the Korean age-specific thyroid dose coefficients for ¹²⁹I and ¹³¹I were considerably lower than those calculated for the world population (25%-76% of the values for the world population). Conclusion: These differences stress the need for Korean-specific internal dose assessments for infants and children, which can be achieved by using the data calculated in this study.

• 한국노년학
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• 제41권1호
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• pp.85-105
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• 2021

본 연구는 활동적 노화의 관점을 적용하여 장기요양시설에서의 돌봄 유형에 관한 다양한 인식유형을 분석하는 데 목적을 둔다. 이를 위해 Q방법론을 적용하였다. WHO의 활동적 노화를 위한 건강, 안전, 참여 세 영역에서 장기요양시설의 돌봄에 관한 다양한 생각을 파악하기 위해 심층면접을 진행하였다. 면접조사에는 장기요양시설 거주 노인, 거주 노인의 성인자녀, 지역사회 거주 노인, 서비스 제공자, 장기요양 전문가 등 35명이 참여하였다. 451개의 Q모집단 중 63개의 Q표본을 추출하였으며, 최종 자료분석에는 43개의 P표본 자료가 활용되었다. QUANL 프로그램을 활용하여 자료를 분석한 결과, 3개의 요인구조(4개 유형)가 적합하며 이는 전체 변량의 30.15%를 설명하는 것으로 나타났다. 현재 장기요양시설의 돌봄은 보호 중심 돌봄(1유형), 참여 중심 돌봄(2유형), 의료연계 중심 돌봄(3유형), 인간 중심 돌봄(4유형)으로 유형화할 수 있다. 본 연구결과를 바탕으로 장기요양시설에서 돌봄의 질적 변화를 위한 제도적, 실천적 함의를 제시하였다.

• 대한치과보철학회지
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• 제61권1호
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• pp.26-32
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• 2023

활동이 많은 소아 청소년 시기에는 치아의 외상이 흔하게 발생한다. 그 중 탈구로 인해 유착이 일어날 경우 임상검사를 통한 진단이 중요하며 성인이 된 후 심미적인 보철 수복을 위해서는 진단에 따른 치료가 중요하다. 본 증례는 외상으로 인해 유착된 치아를 치관절제술과 임플란트 식립을 통한 상악 전치부 심미 보철 수복 증례이다. 치관절제술 후 치관을 이용하여 보철 수복을 위한 공간 유지를 시행하였다. 성인이 된 후 guide surgery를 이용하여 정교한 임플란트 식립과 심미적인 보철 수복을 가능하게 하였으며, 상악 전치부임을 고려하여 원발성 안정성(primary stability) 확인 후 즉시 부하(immediate loading)를 시행하였다. 연조직 지지를 위해 임시치아의 윤곽 변화를 주며 임시치아를 교체하였고 digital wax-up 하여 최종 보철물을 수복하였다.

• 대한한방소아과학회지
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• 제37권3호
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• pp.35-48
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• 2023

Objectives We aimed to analyze changes in growth indicators before and after Korean medicine treatment in patients treated at the pediatric department of a hospital. Methods We analyzed the medical records of children and adolescents under 18 years of age who underwent growth assessment between January 1, 2017 and December 31, 2022. Results A total of 21 patients were selected for this study. After treatment, there was a significant increase in the height percentile, whereas bone age-chronological age (BA-CA) and predicted adult height (PAH) did not show significant changes. No major adverse reactions were observed during the treatment. Growth reassessment was conducted twice for 10 participants. When comparing the growth indicators between the assessment sessions, the height percentile showed an increasing trend between the initial and the first growth reassessment. However, there were no significant differences between BA-CA and PAH across the different assessment periods. Conclusions There is a need to establish evidence for the efficacy and safety of continuous Korean medicine growth treatment through the long-term observation of growth indicators in patients undergoing treatment for two or more periods, as well as observational studies on liver and renal function indicators.