• 대한치과교정학회지
• /
• 제51권5호
• /
• pp.337-345
• /
• 2021

Objective: To investigate the phenotypes and predominant skeletodental pattern in pre-adolescent patients with Pierre-Robin sequence (PRS). Methods: The samples consisted of 26 Korean pre-adolescent PRS patients (11 boys and 15 girls; mean age at the investigation, 9.20 years) treated at the Department of Orthodontics, Seoul National University Dental Hospital between 1998 and 2019. Dental phenotypes, oral manifestation, cephalometric variables, and associated anomalies were investigated and statistically analyzed. Results: Congenitally missing teeth (CMT) were found in 34.6% of the patients (n = 9/26, 20 teeth, 2.22 teeth per patient) with 55.5% (n = 5/9) exhibiting bilaterally symmetric missing pattern. The mandibular incisors were the most common CMT (n = 11/20). Predominant skeletodental patterns included Class II relationship (57.7%), posteriorly positioned maxilla (76.9%) and mandible (92.3%), hyper-divergent pattern (92.3%), high gonial angle (65.4%), small mandibular body length to anterior cranial base ratio (65.4%), linguoversion of the maxillary incisors (76.9%), and linguoversion of the mandibular incisors (80.8%). Incomplete cleft palate (CP) of hard palate with complete CP of soft palate (61.5%) was the most frequently observed, followed by complete CP of hard and soft palate (19.2%) and CP of soft palate (19.2%) (p < 0.05). However, CP severity did not show a significant correlation with any cephalometric variables except incisor mandibular plane angle (p < 0.05). Five craniofacial and 15 extra-craniofacial anomalies were observed (53.8% patients); this implicated the need of routine screening. Conclusions: The results might provide primary data for individualized diagnosis and treatment planning for pre-adolescent PRS patients despite a single institution-based data.

• 대한본초학회지
• /
• 제24권1호
• /
• pp.121-131
• /
• 2009

Objectives：This study was designed to investigate the effects of herbal composition and fermented Cervi Pantotrichum Cornu on the growth of longitudinal bone in the adolescent male rats. Methods： Longitudinal bone growth was measured by fluorescence microscopy. To examine the effects on the growth plate metabolism, the total height of growth plate and the induction of local insulin-like growth factor-1 (IGF-1) and bone morphogenetic protein-2 (BMP-2) were measured. Results： The herbal composition treatment enhanced longitudinal bone growth and total heght of growth plate and promoted the induction of local IGF-1 and BMP-2 of growth plate. Conclusions： This study showed that the herbal composition have the effect of bone growth in adolescent rats and might be used for the growth delayed adolescent and inherent growth failure patient.

• 대한한방소아과학회지
• /
• 제32권1호
• /
• pp.54-74
• /
• 2018

Objectives The purpose of this study is to investigate recent trend of diseases in Korean pediatrics and adolescent patients treated with oriental medicine. Methods Using data from the Korean statistical information service and healthcare bigdata hub, top 500 diseases pediatrics and adolescents that were treated with oriental medicine from 2012 to 2016 in admission and outpatient department was collected. Results From the inpatient study, majority of the subjects were between 15 to 19 years old (62.74%), followed by 10 to 14 years old, 5 to 9 years old and under 5 years old. In the outpatient department study, majority was 15 to 19 years old (36.51%), followed by 10 to 14 years old, under 5 years old, 5 to 9 years old. In systemic division of admission part, the most common disease was musculoskeletal related which was 72.32%, followed by brain, nerve, respiratory, dermatology and digestive related diseases. In systemic division of outpatient department, respiratory disease was the most common (41.81%), followed by digestive, dermatology, brain and nerve diseases. For under 5 years old patient group, respiratory disease was the most common, 29.86%, followed by dermatology, musculoskeletal, digestive related diseases. For 5 to 19 years old group of patients, musculoskeletal disease was most common. For the 5 to 14 years old patient group, respiratory related disease was the most common followed by dermatology and digestive diseases. For 15 to 19 years old patient group, digestive disease was the most common followed by respiratory and dermatology related diseases. For under 5 to 9 years old outpatient group, respiratory disease was the most common, and for under 5-year-old group, digestive, growth development, and dermatology disease were common. For the 5 to 9 years old group of patients, musculoskeletal related disease was the most common followed by digestive and dermatology related diseases. For the 10 to 19 years old patient group, musculoskeletal was the most common. For the 10 to 14 years old patient group, respiratory related disease was the most common followed by digestive, dermatology disease. For the 15 to 19 years old patient group, digestive related disease was the most common followed by respiratory, dermatology diseases. Musculoskeletal disease increased every year, in both inpatient and outpatient. Respiratory, brain, nerve, digestive related diseases were generally decreased. In outpatient, respiratory diseases were increased every year but brain, nerve, digestive related diseases were generally decreased. Conclusions More studies about the oriental medicine in chronic disease, such as allergy, metabolic syndrome, in Korean pediatrics and adolescents are needed.

• Journal of Trauma and Injury
• /
• 제33권1호
• /
• pp.48-52
• /
• 2020

Composite skull defects in patients with severe head injuries are very challenging to manage. The dilemma when deciding whether to perform a definitive reconstruction is how long to wait for physiological recovery before an intervention complicates the situation. The inability of such patients to tolerate prolonged anesthetic exposure is a driving factor for performing the minimal intervention necessary to facilitate recovery. Herein, we present a case involving the successful immediate reconstructive treatment of a severely head-injured adolescent with a composite scalp defect secondary to trauma. A 14-year-old boy sustained a severe head injury from a motor vehicle accident with a composite scalp defect in the right fronto-parietal region. The frontal lobe was exposed, and the right eye was crushed and devitalized. The patient was deeply unconscious for 3 days, without any significant improvements before reconstructive surgery was proposed due to fear of possible meningitis resulting from the exposure of brain structures. We successfully managed the patient with a fronto-parieto-occipital flap, after which the patient promptly recovered consciousness.

• Journal of Yeungnam Medical Science
• /
• 제38권3호
• /
• pp.251-257
• /
• 2021

Vedolizumab (VDZ) has been approved for the treatment of inflammatory bowel diseases (IBDs) in patients aged ≥18 years. We report a case of a pediatric patient with Crohn disease (CD) who was successfully treated with VDZ. A 16-year-old female developed severe active pulmonary tuberculosis (TB) during treatment with infliximab (IFX). IFX was stopped, and TB treatment was started. After a 6-month regimen of standard TB medication, her pulmonary TB was cured; however, gastrointestinal symptoms developed. Due to the concern of the patient and parents regarding TB reactivation on restarting treatment with IFX, VDZ was started off-label. After the second dose of VDZ, the patient was in clinical remission and her remission was continuously sustained. Ileocolonoscopy at 1-year after VDZ initiation revealed endoscopic healing. Therapeutic drug monitoring conducted during VDZ treatment showed negative antibodies to VDZ. No serious adverse events occurred during the VDZ treatment. This is the first case report in Korea demonstrating the safe and effective use of VDZ treatment in a pediatric CD patient. In cases that require recommencement of treatment with biologics after recovery of active pulmonary TB caused by anti-tumor necrosis factor agents, VDZ may be a good option even in pediatric IBD.

• 대한소아치과학회지
• /
• 제24권3호
• /
• pp.651-659
• /
• 1997

This report presents a case of adolescent patient who had multiple impacted teeth and no systemic disease, and was treated with removable and fixed orthodontic appliances. The results obtained through these cases were summarized as follows : 1. Even in the case without systemic disease, there can be the delayed eruption of multiple teeth 2. If the root formation is not completed, root have no excessive curvature, axial inclination of the tooth is not excessive, and there is eruption space, the tooth can be induced to normal occlusion. 3. Since esthetically proper occlusion and dentition was acquired by recovery of the impacted teeth to normal occlusion, the prosthodontic treatment after extraction of the impacted teeth was less needed. 4. This treatment brought psychological stability to pubertal patient who was interested in his facial profile.

• 대한한방소아과학회지
• /
• 제21권3호
• /
• pp.97-107
• /
• 2007

Objectives The purpose of this study is to report a case showed significant consult in treating Idiopathic chronic hyperventilation patient with oriental medicine. Methods The patient had suffered from dysypnea for 7 months, so we treated her with herbal medicine, acupuncture, laser, CEP nebulizer and cupping. Results and Conclusions This study shows that oriental medicine works for treating Idiopathic chronic hyperventilation. For more accurate studies, further studies are needed with more clinical cases.

• 대한치과교정학회지
• /
• 제53권1호
• /
• pp.54-64
• /
• 2023

This case report describes skeletal anchorage-supported maxillary protraction performed with the Alternate Rapid Maxillary Expansion and Constriction (AltRAMEC) protocol over a treatment duration of 14 months in a 16-year-old female patient who was in the late growth-development period. Miniplates were applied to the patient's aperture piriformis area to apply force from the protraction appliance. After 9 weeks of following the Alt-RAMEC protocol, miniplates were used to transfer a unilateral 500-g protraction force to a Petit-type face mask. A significant improvement was observed in the soft tissue profile in measurements made both cephalometrically and in three dimensional photographs. Subsequently, the second phase of fixed orthodontic treatment was started and the treatment was completed with the retention phase. Following treatment completion, occlusion, smile esthetics, and soft tissue profile improved significantly in response to orthopedic and orthodontic treatment.

• 대한치과교정학회지
• /
• 제34권2호
• /
• pp.177-188
• /
• 2004

교정치료 시기의 적기이며 내원 환자의 많은 부분을 차지하고 있는 청소년기 교정환자의 치료 협조도에 영향을 미치는 요소들에 대해 파악하고자 강릉대학교 치과병원 교정과에서 10개월 이상 동적 치료를 받은 중학교 1학년 이상, 고등학교 3학년 이하 남녀 청소년 60명 (남자 23명, 여자 37명)을 대상으로 인구학적 변인에 따른 치료 협조도를 비교하고 성별, 학령, 치료 협조도에 따른 교정적 태도 척도, 교정용 내외통제소재 척도를 측정, 비교 분석하여 다음과 같은 결과를 얻었다. 1. 교정용 내외통제소재 척도를 조사 분석한 결과 외적통제-부모의 항목에서 성별에 따라 유의한 차이가 인정되었으며(p<0.05) 남학생이 여학생보다 높은 외적통제-부모의 양상을 나타내었다. 2. 교정용 내외통제소재 척도를 조사 분석한 결과 협조적인 환자 군과 비협조적인 환자 군간에 외적통제-부모 항목에서 유의성 있는 차이가 인정되었으며(p<0.05) 교정치료에 대해 협조적인 군에서 외적통제-부모에 대한 인식이 보다 높았다. 3. 교정 치료를 권유하거나 치료받기를 결정한 사람과 치료시의 협조도 사이에는 통계적으로 유의한 차이가 인정되었으며(p<0.05) 환자 자신의 결정에 의한 경우 가장 높은 협조도를 나타내었다. 4. 치료기간과 협조도 사이에 유의한 차이가 인정되었으며 (p<0.05) 치료기간이 길어질수록 협조도는 지속적으로 감소하였다. 5. 교정적 태도 척도를 조사 분석한 결과 성별, 중학생과 고등학생간, 협조적인 환자군과 비협조적인 환자군 사이 에 통계적으로 유의한 차이가 없었다. 6. 교정치료 시 협조정도와 한자의 성별, 연령, 가족관계, 부모의 직업 및 학력, 학업성적, 양치횟수 등의 변인과는 통계적으로 유의한 차이가 인정되지 않았다.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• 제24권2호
• /
• pp.90-95
• /
• 2013

Botulinum toxin, a neurotoxin, is known to be an inhibitor of cholinergic neuromuscular transmission. Recently, it was reported that the administration of botulinum toxin is effective for the treatment of focal neurological motor disorders such as cervical dystonia, blepharospasm, hemifacial spasm, spasmodic dysphonia, and writer's cramp. Several case studies reported that the botulinum toxin was administered for the treatment of motor tic or vocal tic. It was found that this toxin reduces the frequency and severity of the tic as well as the premonitory urge and symptoms. In our case study, a noticeable decrease of motor tic symptom was observed after an intramuscular injection of 300mg of botulinum toxin in an 18-year-old patient with Tourette's disorder who showed only a little improvement of motor tic and vocal tic symptoms after treatment with antipsychotic drugs for several years. This case is reported in our study and literature survey was undertaken for reviewing similar cases. In our study, an 18-year-old boy diagnosed with Tourette's disorder based on Diagnostic and Statistical Manual of Mental Disorders, fourth edition presented with the following scores : the Clinical Global Impression scale, Yale Global Tic Severity Scale (motor/vocal/severity), Premonitory Urge Score, Korean Attention-Deficit Hyperactivity Disorder Rating scale, and Kovac Depression scale which were performed prior to the treatment were 5, 21/5/50, 100, 17, and 18 points, respectively. Two weeks after the injection of botulinum toxin, the scores were 4, 17/5/40, 50, 16, and 19 points, respectively. Eight weeks after the injection of botulinum toxin, they had become 3, 15/5/30, 25, 16, and 20 points, respectively, which clearly indicates a noticeable decrease of motor tic symptom.