• 제목/요약/키워드: Administration Research

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INHIBITION OF NEURITE OUTGROWTH AND TRANSCRIPTION FACTOR ACTIVATION BY OCHRATOXIN A IN CULTURED PC-12 CELLS

  • Hong, Jin-Tae;Oh, Jae-Ho;Jung, Kyoung-Mi;Lee, Eun-Hee;Park, Ki-Sook;Song, Chi-Won;Jung, Hai-Kwan;Lee, Myung-Koo;Yang, Ki-Hwa;Chung, Soo-Youn
    • Proceedings of the Korean Society of Toxicology Conference
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    • 한국독성학회 2001년도 International Symposium on Signal transduction in Toxicology
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    • pp.168-168
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    • 2001

  • The mycotoxin, ochratoxin A (OTA) has been known to induce microcephaly in animals and in vitro whole embryo. Cytotoxic effect and inhibition of cell differentiation were proposed as underlying mechanisms responsible for OTA-induced microcephaly.(omitted)

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DIETARY RISK ASSESSMENT FOR POLYCYCLIC AROMATIC HYDROCARBONS IN FOOD

  • Hyomin LEE;Eunkyung YOON;Yoonho CHOI;Gunyoung LEE;Yonsook JO;Kisung KWON;Soyoung CHUNG;Myungchul KIM;Jisun YANG
    • Proceedings of the Korean Society of Toxicology Conference
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    • 한국독성학회 2002년도 Current Trends in Toxicological Sciences
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    • pp.136-136
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    • 2002

  • Polycyclic aromatic hydrocarbons(PAHs) vary in their carcinogenic potencies. The more potent PAHs carcinogens are 3-methylcholantheren and 7, 12- dimethyl benzo(a)anthracene, while dibenzo(a, c)anthracene has very little carcinogenic activity. Risk assessment of chemical mixture containing various congeners which toxic potency are each different, are conducted using toxic equivalency factors(TEFs).(omitted)

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