• Title/Summary/Keyword: Administration Research

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Effect of di-n-butyl-phthalate on cytotoxic activity of natural killer cells in C57BL/6

  • Juno H. Eom;Chung, Seung-Tae;Kim, Jin-Ho;Park, Jae-Hyun;Chung, Hyung-Jin;Hwang, In-Chang;Kim, Dong-Sup;Kim, Hyung-Soo
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.05a
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    • pp.114-114
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    • 2001
  • Di-n-butyl phthalate (DBP) is not only a plasticizer and solvent used in industry but also one of endocrine disruptor chemicals, a low level contaminant found in a wide variety of different media ranging from drinking water to infant formulae. To evaluate the cytotoxic function of NK cells in mice after contact with DBP, C57BL/6 female mice were orally dosed with di-n-butyl phthalate (250, 500, or 750 mg/kg body weight) for 14 consecutive days, and the control mice were administered vehicle (corn oil).(omitted)

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EFFECTS OF DI(N-BUTYL) PHTHALATE, AN ENDOCRINE DISRUPTOR ON THE IMMUNE SYSTEM OF PREGNANT SD RATS AND THEIR PUPS

  • Juno H. Eom;Chung, Seung-Tae;Park, Jae-Hyun;Lee, Jong-Kwon;Chung, Hyung-Jin;Kwan, Tae-Woo;Kim, Hyung-Soo;Oh, Hae-Young
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.05a
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    • pp.98-98
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    • 2002
  • Di-n-butyl phthalate(DBP) is one of the most commonly used phthalic acid esters(PAEs). It is extensively used as a plasticizer in elastomers and explosives, as a solvent for printing inks and resins and as a textile lubricating agent. It is also present in the formulations of various cosmetic products.(omitted)

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ALTERATIONS IN SEX STEROID RECEPTOR LEVELS AND HOXA-10 EXPRESSIONS OF THE UTERI FOLLOWING NEONATAL EXPOSURE TO PERMETHRIN IN FEMALE MICE

  • Kim, Byung-Ho;Kim, Soon-Sun;Rhee, Gyu-Seek;Sohn, Kyung-Hee;Kwack, Seung-Jun;Kim, So-Hee;Lee, Rhee-Da;Lee, Hyun-Joo;Park, Sung-Soo
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2002.11b
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    • pp.167-167
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    • 2002
  • Many pesticides possess hormonal activity and have been thus classified as endocrine disruptors. Permethrin, a pyrethroid insecticide has little been characterized to it's hormonal potential. In the present study, effects of neonatal exposure to permethrin on the sex steroid receptor levels and hoxa-10 expression of the uteri were investigated in female mice.(omitted)

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Profiles of Compositional Components in Vegetable Soybeans (Glycine max (L.) Merr.)

  • Lee, Jin-Hwan;Baek, In-Youl;Ko, Jong-Min;Kang, Nam-Suk;Kim, Hyun-Tae;Han, Won-Young;Shin, Sang-Ouk;Park, Keum-Yong;Oh, Ki-Won;Ha, Tae-Joung;Park, Ki-Hun
    • Journal of Applied Biological Chemistry
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    • v.50 no.2
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    • pp.63-69
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    • 2007
  • Compositional components such as isoflavone, protein, oil, fatty acid, and free sugar in Korean vegetable soybeans were examined with four cultivars including Hwaeomputkong, Keunolkong, Mirang, and Danmi 2. In the isoflavone, Mirang cultivar showed the highest content ($967.1{\mu}g/g$), whereas Keunolkong was the lowest content ($535.9{\mu}g/g$). The malonylglucosides were the predominant isoflavone type followed by the glucoside, aglycone, and acetyl glucoside forms, respectively. In the protein content, Hwaeomputkong was the lowest (41.7%) and Danmi 2 was the highest (45.9%). The oil contents were 11.5 to 21.2% and Mirang cultivar was the lowest. The fatty acid compositions of the oil extracts exhibited that linoleic acid was the highest (33.6-42.5%), followed by oleic, palmitic, linolenic, and stearic acids. Whereas, oleic acid ($46.7{\pm}2.0%$) was more than linoleic acid ($33.6{\pm}1.3%$) in Mirang cultivar. In the free sugar contents, Hwaeomputkong cultivar showed the highest level and sucrose ($5.52{\pm}0.49%$) appeared to be most prevalent in vegetable soybeans.

Changes in rutin contents and antioxidant properties of tartary buckwheat seeds and groats induced by roasting

  • Kim, Su Jeong;Sohn, Hwang Bae;Kim, Geum Hee;Lee, Yu Young;Hong, Su Young;Kim, Ki Deog;Chang, Dong Chil;Suh, Jong Taek;Koo, Bon Cheol;Kim, Yul Ho
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2017.06a
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    • pp.271-271
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    • 2017
  • Tartary buckwheat is known for its high rutin (quercetin 3-rutinoside) content which has antioxidant, anti-inflammatory, and anticarcinogenic effects. The buckwheat tea which is popular in Korea, is dependent on the quality of applied processing methods (steaming, dehuling, and roasting). This study focused on the evaluation of changes in rutin and anti-oxidant contents during the processing of tartary buckwheat tea. Raw tartary buckwheat seeds contains the highest quantities of rutin (2,212 mg/100 g D.W.). Soaking in water and steaming the whole seeds of tartary buckwheat significantly decreased its rutin and quercetin contents. Whereas the contents of rutin and quercetin in dehulled groats increased after steaming. The process of roasting with $70-80^{\circ}C$ for 2-3 min significantly decreased the contents of rutin (992 mg/100 g D.W.) and quercetin (12.8 mg/100 g D.W.). In the processing of tartary buckwheat tea, rutin content dropped about 45% in comparison with raw whole seeds.

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Phylogenetic Placement and Morphological Characterization of Sclerotium rolfsii (Teleomorph: Athelia rolfsii) Associated with Blight Disease of Ipomoea batatas in Korea

  • Paul, Narayan Chandra;Hwang, Eom-Ji;Nam, Sang-Sik;Lee, Hyeong-Un;Lee, Joon-Seol;Yu, Gyeong-Dan;Kang, Yong-Gu;Lee, Kyeong-Bo;Go, San;Yang, Jung-Wook
    • Mycobiology
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    • v.45 no.3
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    • pp.129-138
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    • 2017
  • In this study, we aimed to characterize fungal samples from necrotic lesions on collar regions observed in different sweetpotato growing regions during 2015 and 2016 in Korea. Sclerotia appeared on the root zone soil surface, and white dense mycelia were observed. At the later stages of infection, mother roots quickly rotted, and large areas of the plants were destroyed. The disease occurrence was monitored at 45 and 84 farms, and 11.8% and 6.8% of the land areas were found to be infected in 2015 and 2016, respectively. Fungi were isolated from disease samples, and 36 strains were preserved. Based on the cultural and morphological characteristics of colonies, the isolates resembled the reference strain of Sclerotium rolfsii. Representative strains were identified as S. rolfsii (teleomorph: Athelia rolfsii) based on phylogenetic analysis of the internal transcribed spacer and large subunit genes along with morphological observations. To test the pathogenicity, sweetpotato storage roots were inoculated with different S. rolfsii strains. 'Yulmi' variety displayed the highest disease incidence, whereas 'Pungwonmi' resulted in the least. These findings suggested that morphological characteristics and molecular phylogenetic analysis were useful for identification of S. rolfsii.

The Change of Arabinoxylan, Phytic Acid and Vitamin E Contents Whole Wheat Flour depends on the Millig Rate Milling Rate in the Korean Wheat Cultivar 'Saekuemkang'

  • Go Eun Lee;Kyeong-Hoon Kim;Jinhee Park;Kyeong-Min Kim;Chang-Hyun Choi;Mina Kim ;Myoung Hui Lee;Chon-Sik Kang;Jiyoung Shon;Jong-Min Ko
    • Proceedings of the Korean Society of Crop Science Conference
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    • 2022.10a
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    • pp.299-299
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    • 2022
  • Whole wheat is rich in dietary fiber and contains various biological activity substances such as arabinoxylan, phytic acid and phenolic compounds. However, excessive fiber contents of whole wheat has a negative effect on dough formation, making it difficult to process. In this study, we tried to improve the usability of whole wheat by suggesting an appropriate degree of purification of whole wheat from 'Saekeumkang', a domestic wheat cultivar containing protein and gluten suitable for noodle production. The contents of arabinoxylan, phytic acid, and vitamin E were measured in the polishing rate range of 5-20% of whole wheat flour. As the milling ratio increased, the flour properties improved. The arabinoxylan and phytic acid content of whole wheat were 67.95 mg/g and 0.87 mg/g, but when milled at 20%, arabinoxylan and phytic acid were 60% and 80% of whole wheat, respectively. And as the milling ratio increased, the vitamin E content tended to decrease (whole wheat: 4.063 mg/100 g, 20% milled: 2.96 mg/100 g), However, the vitamin E composition ratio did not change. On the other hand, α-tocopherol showed the greatest than other vitamin E isomers. Therefore, further studies needed to optimize milling rate to improve the final product while maintaining the approximate nutritional and functional value of the whole wheat.

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Differences in fine dust emissions based on bedding type and quantity in horse stables

  • Ji Hyun Yoo;Jong An Lee;Jae Young Choi;Sang Min Shin;Hyeon Ah Kim;Mi Young Won;Yong Jun Kang;Hee Chung Ji;In Cheol Cho;Jin Hyoung Kim
    • Korean Journal of Agricultural Science
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    • v.50 no.4
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    • pp.917-925
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    • 2023
  • Efforts for developing the domestic horse industry in South Korea are evident through the various national policies. Proper management of stables for ensuring the health of horses is essential to sustain the growing equine industry. This study aimed to measure the fine dust emissions in stables based on the type and quantity of bedding used for horses, for establishing guidelines pertaining to bedding use in stables. The stables accommodated 12 horses. Sawdust, wood shavings, wood pellet, and straw were chosen as treatments. Three different quantities (approximately 3, 6, and 9 cm in height) were applied for each type. Fine dust measurements were carried out at three time points, with each measuring period lasting for approximately three weeks. Measurements included PM2.5 and PM10 fine dust levels. The initial analysis revealed that, sawdust with 9 cm bedding had the highest dust levels; approximately 54.6 ㎍/m3, for PM2.5 and 95.3 ㎍/m3, for PM10. Sawdust bedding at the highest quantity (9 cm) exhibited significantly higher initial fine dust emissions. These findings suggest that bedding materials with smaller particle size, such as sawdust and wood shavings, tend to produce finer dust. Initially, the fine dust emissions decreased in all bedding types and quantities, possibly due to the increased moisture content of bedding owing to horse manure production. However, emissions increased subsequently due to ammonia production.