• Korean Journal of Veterinary Research
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• v.37 no.4
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• pp.843-854
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• 1997

Sixteen mammary gland tumors were collected from Seoul National University and Kangwon National University. The average age of the bitches with mammary gland tumor was 10 years. Total 17(60.7%) out of 28 tumor masses observed in 4th and 5th glands. Classification of these tumors according to Hampe and Misdorp were simple adenoma, complex adenoma, benign mixed tumor, papillary adenocarcinoma, solid adenocarcinoma and malignant mixed tumor. Immunohistochemical reaction of the intermediate filaments against normal canine mammary gland showed as followed; anti-cytokeratin 18 was strong and anti-cytokeratin 14 was moderate to the luminal epithelium. Anti-cytokeratin 14 and anti-pancytokeratin to the myoepithelium were showed strong, but anti-vimentin was weak in reactivity. Anti-vimentin to the interstitial cells was represented strong reactivity. The origin of cartilage in mixed tumor of canine mammary gland was studied immunohistochemically with antibodies against intermediate filament. In mammary gland mixed tumors, cartilage tumor tissues were surrounded with the irregularly demarcated three zones composed of adjacent star shaped cells in myxoid areas, proliferative spindle shaped cells and basal located proliferated cells. From basal proliferated cells to star shaped cells, the immunohistochemical reactivity of myoepithelium specific anti-pancytokeratin was decreased gradually and the reactivity of interstitial cell specific anti-vimentin was increased gradually. Based on these immunohistochemical staining patterns, we suggested that the origin of cartilagenous components in canine mammary gland mixed tumor is most likely to the proliferation and metaplsia of myoepithelium.

• Journal of the Korea Computer Graphics Society
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• v.23 no.1
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• pp.17-24
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• 2017

We propose an efficient method to express water spray effects by adaptively modeling air particles in particle-based water simulation. In real world, water and air continuously interacts with each other around free surfaces and this phenomenon is commonly observed in waterfall or sea with rough waves. Due to thin spray water, the interfaces between water and air become vague and the interactions between them lead to heavy vortex phenomenon. To express this phenomenon, we propose methods of 1) generating adaptive air cell in particle-based water simulation, 2) expressing water spray effects by creating and evolving air particles in the adaptive air cells, and 3) guaranteeing robustness of simulation by solving drifting problem occurred when adjacent air particles are insufficient. Experiments convincingly demonstrate that the proposed approach is efficient and easy to use while delivering high-quality results.

• Journal of Korean Neurosurgical Society
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• v.44 no.4
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• pp.249-255
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• 2008

Objective : In Moyamoya disease, the primary goal of treatment is to improve collateral circulation through angiogenesis. In the present study, we obtained and sub-cultured bone marrow stromal cells (BMSCs) from rats without a cell-mediated immune response. Then, we injected the labeled BMSCs directly into adjacent temporal muscle during encephalomyosynangiosis (EMS). Three weeks after BMSC transplantation, we examined the survival of the cells and the extent of neovascularization. Methods : We divided 20 rats into a BMSC transplantation group (n=12) and a control group (n=8). Seven days after the induction of chronic cerebral ischemia, an EMS operation was performed, and labeled BMSCs ($1{\times}106^6/100\;{\mu}L$) were injected in the temporal muscle for the transplantation group, while an equivalent amount of culture solution was injected for the control group. Three weeks after the transplantation, temporal muscle and brain tissue were collected for histological examination and western blot analysis. Results : The capillary/muscle ratio in the temporal muscle was increased in the BMSC transplantation group compared to the control group, showing a greater increase of angiogenesis (p<0.05). In the brain tissue, angiogenesis was not significantly different between the two groups. The injected BMSCs in the temporal muscle were vascular endothelial growth factor (VEGF)-positive by immunofluorescence staining. In both temporal muscle and brain tissue, the expression of VEGF by western blot analysis was not much different between the two groups. Conclusion : During EMS in a chronic cerebral ischemia rat model, the injection of BMSCs resulted in accelerated angiogenesis in the temporal muscle compared to the control group.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.15 no.9
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• pp.1840-1846
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• 2011

It is necessary to estimate the Doppler spectrum for each range cell for the extraction of useful information from the return echoes in radar systems used for the remote sensing purpose such as detection of moving targets and weather surveillance. The signal amplitude in the beat frequency band is the important parameter in the detection and tracking of targets. However, strong clutter echoes do exist in most radar operation environments and the system phase noise spreads both the clutter and signal echoes of the target. In this paper, the effects of this system phase noise are analyzed concerning the clutter and the signal beat spectrum. It is shown that the separation capability of adjacent beat signal depends on the degree of spread in the clutter and beat signal caused by the radar system phase noise

• 한국신재생에너지학회:학술대회논문집
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• 2007.06a
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• pp.280-283
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• 2007

The first grid-connected, building-integrated transparent amorphous silicon photovoltaic installation has been operated since October 2004 in Yongin, Korea. The 2.2kWp transparent PV system was applied to the facade of entrance hall in newly constructed KOLON E&C R&D building. The PV module is a nominal 0.98m ${\times}$ 0.95m, 10% transparent, laminated, amorphous(a-Si) thin-film device rated at 44 Wp per module. To demonstrate the architectural features of thin film PV technologies for daylighting application, transparent PV modules are attached to the building envelope with the form of single glazed window and special point glazing(SPG) frames. Besides power generation, the 10% transmittance of a-Si PV module provides very smooth natural daylight to the entrance hall without any special shading devices for whole year. The installation is fully instrumented and is continuously monitored in order to allow the performance assessment of amorphous silicon PV operating at the prevailing conditions. This paper presents measured power performance data from the first 12 months of operation. For the first year, annual average system specific yield was just 486.4kWh/kWp/year which is almost half of typical amorphous silicon PV output under the best angle and orientation. It should be caused by building orientation and self-shading of adjacent mass. Besides annual power output, various statistical analysis was performed to identify the characteristics of transparent thin film PV system.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.30 no.9A
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• pp.749-754
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• 2005

It is well-known that mobile communication systems are usually limited in their performance and capacity by three major impairments, which are multipath fading, delay spread and co-channel interference (CCI). OFDMA (OFDM-FDMA) system can cope with the multipath fading and delay spread easily due to the beneficial properties of OmM technology. Though OFDMA scheme avoids intra-cell interference using the orthogonality among subcarriers, the scheme contains difficulty of reducing co-channel interference. Therefore, in this paper, adaptive antenna techniques are deployed into OFDMA/TDD system to minimize the co-channel interference induced by adjacent cells and to enhance the uplink performance. For the improvement of downlink performance, we apply TxAA (Transmit Adaptive Array), a kind of transmit diversity technique, utilizing preamble symbols for training antenna may into OFDMA/TDD transmitter side. Simulation results show that the uplink and downlink performance under multipath Rayleigh fading channel improved 9dB and 7dB each compared with the case of single antenna system at target BER $10^{-3}$ .

• KIEAE Journal
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• v.16 no.1
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• pp.89-94
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• 2016

This study is part of three-dimensional(3D) heat transfer analysis program developmental process. The program is being developed without it's own built in 3D-modeller. So 3D-model must be created from another 3D-modeller such as generic CAD programs and imported to the developed program. After that, according to the 3D-geometric data form imported model, 3D-mesh created for numerical calculation. But the 3D-model created from another 3D-modeller is likely to have errors in it's geometric data such as mismatch of position between vertexes or surfaces. these errors make it difficult to create 3D-mesh for calculation. These errors are must be detected and cured in the pre-process before creating 3D-mesh. So, in this study four kinds of filters and functions are developed and tested. Firstly, 'vertex error filter' is developed for detecting and curing for position data errors between vertexes. Secondly, 'normal vector error filter' is developed for errors of surface's normal vector in 3D-model. Thirdly, 'intersection filter' is developed for extracting and creating intersection surface between adjacent objects. fourthly, 'polygon-line filter' is developed for indicating outlines of object in 3D-model. the developed filters and functions were tested on several shapes of 3D-models. and confirmed applicability. these developed filters and functions will be applied to the developed program and tested and modified continuously for less errors and more accuracy.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.8
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• pp.3903-3909
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• 2016

Purpose: To evaluate the expression of Her2/neu and Ki-67 in benign and malignant gallbladder lesions, and to establish correlations with clinico-pathologic parameters. Materials and Methods: A retrospective analysis was conducted on formalin fixed paraffin embedded (FFPE) benign (n=25) and malignant gallbladder (n=25) tissue samples. Hematoxylin and eosin stained slides of each case were reviewed for: type of malignancy (whether adenocarcinoma, squamous cell carcinoma, or any other type), grade (well, moderate, and poor), depth of invasion, pre-neoplastic changes in adjacent mucosal epithelium like metaplasia and dysplasia. Immunohistochemistry for Her 2 neu and Ki-67 was performed and data analysis was conducted using SPSS 17 software. Chi-square test was used to compare categorical/dichotomous variables. P value of ${\leq}0.05$ was considered significant. Results: The difference of Her 2 neu expression and Ki67 index between benign and malignant groups was found to be statistically significant. Her2/neu positivity did not have any significant correlation with various clinicopathological parameters other than liver involvement. 5 cases of gallbladder cancer showed both Her2/neu and Ki67 positivity. Ten cases were Ki67 positive but Her2/neu negative while one case was Her2/neu positive but Ki67 negative. Conclusions: The present study demonstrated overexpression of Her2/neu and Ki67 in gallbladder cancer. A trend of decreasing Her2/neu expression with increasing grade of tumor was observed. Furthermore, greater Ki67 positivity was found in cases with lymph node metastasis and distant metastasis. Future studies with a larger number of patients will be required to precisely define the correlation of Her2/neu expression and Ki67 positivity with clinicopathological parameters. The results however are encouraging and suggest evaluation of Her2/neu as a candidate for targeted therapy.

• Journal of Environmental Science International
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• v.21 no.6
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• pp.725-738
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• 2012

Recently, a variety of GIS-based tools enabling to generate topographic parameters for hydrologic and hydraulic researches have been developed. However, most of GIS-based tools are usually insufficient to estimate and visualize river channel slopes especially along the river network, which can be possibly utilized for many hydraulic equations such as Manning's formula. Many existing GIS-based tools have simply averaged cell-based slopes for the other advanced level of hydrologic units as likely as the mean watershed slope, thus that the river channel slope from the simple approach resulted in the inaccurate channel slope particularly for the mountain region where the slope varies significantly along the downstream direction. The paper aims to provide several more advanced GIS-based methodologies to assess the river channel slopes along the given river network. The developed algorithms were integrated with a newly developed tool named RiverSlope, which adapted theoretical formulas of river hydraulics to calculate channel slopes. For the study area, Han stream in the Jeju island was selected, where the channel slopes have a tendency to rapidly change the upstream near the Halla mountain and sustain the mild slope adjacent to watershed outlet heading for the ocean. The paper compared the simple slope method from the Arc Hydro, with other more complicated methods. The results are discussed to decide better approaches based on the given conditions.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.42 no.1
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• pp.111-118
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• 2005

The shape of vertical pattern of base station antenna affects greatly quality of the communication of not only a service zone but also adjacent cells and then it is an important point to be considered in designing cell coverage. Currently type of vertical patterns to be applied to base station antenna are divided into five classes. In designing antenna, these five classes are applied solely or compositely according to the environment to be used antenna. In this paper, the dual polarized antenna for base station that is with a continuous electrical down tilting and with a shaped beam pattern, that an upper side lobe is suppressed and a lower null is filled, is designed and fabricated for synthesizing of the shape beant the pattern synthesis methods proposed by R. S. Elliott is used sequentially and for the electrical don tilting, the phased array theory is applied. Measured results show the down tilting range from 0° to 14°, the gain of Min. 13.3dBi and the upper side lobe of Max. -23dB. And we verified that upper side lobe is not to vary greatly and null filling performance is favorable overall.