• Journal of Pharmaceutical Investigation
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• 제29권2호
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• pp.137-143
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• 1999

Ketoprofen together with various permeation enhancers was incorporated into a novel soft hydrogel which is semi-solid in a container and to form a thin film within a few minutes after applying on the skin. The effect of various enhancers on the skin permeation of ketoprofen from a soft hydrogel was investigated using in vitro and in vivo method. In vitro rat skin permeation of ketoprofen from soft hydrogel was conducted using modified Keshary-Chien diffusion cells. In vivo ketoprofen absorption was also investigated in rats, and the results were compared with that of commercial products. Anti-inflammatory activities were determined using carrageenan-induced paw edema method and adjuvant-induced arthritis method in rats. The anti-inflammatory activity of ketoprofen soft hydrogel formulation with that of commercial products were compared. In vitro as well as in vivo studies showed that $HPE-101^{\circledR}$ was the most effective skin permeation enhancer among those used in this study. Addition of an adhesive (polyisobutylene) in the soft hydrogel decreased skin permeation of ketoprofen. Paw edema and anti-arthritis tests showed that soft hydrogel containing $HPE-101^{\circledR}$ was more effective than the commercial products, which was consistent with the in vivo absorption experiment results.

• 한국철도학회논문집
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• 제13권1호
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• pp.78-83
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• 2010

포장궤도에서는 프리팩 콘크리트방식으로 도싱자갈을 충전층의 골재로 활용한다. 골재의 가장 중요한 조건은 모르터와의 부착력이며 이를 위하여 표면의 불순물을 최대한 제거하여야 한다. 국내에서 개발한 포장궤도 공법에서는 기존의 수세척방식을 대체하는 친환경 건식세척기술을 개발하였다. 건식세척은 직경 0.3~0.5mm 내외로 파쇄한 경질 재료를 고압으로 분사시켜 골재 표면을 박피시키는 방식이다. 본 논문에서는 블라스팅기술의 세척 효율을 향상시키기 위한 방안으로 현재 운용중인 장비조건하에서 분사 재료 및 시간 별 골재 잔입자 함량, 염화물 함유량, LA마모율, 압축강도시험 등을 실시하여 가장 효율적인 세척 재료 및 공정을 제시하고자 하였다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 추계학술대회 논문집 전기물성,응용부문
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• pp.30-32
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• 2005

This paper reports on an LTCC-based packaging method using Au/Sn eutectic bonding process for RF MEMS applications. The proposed packaging structure was realized by a micromachining technology. An LTCC substrate consists of metal filled vertical via feedthroughs for electrical interconnection and Au/Sn sealing rim for eutectic bonding. The LTCC capping substrate and the glass bottom substrate were aligned and bonded together by a flip-chip bonding technology. From now on, shear strength and He leak rate will be measured then the fabricated package will be compared with the LTCC package using BCB adhesive bonding method which has been researched in our previous work.

• International Journal of Advanced Culture Technology
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• 제3권2호
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• pp.34-41
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• 2015

Bonding strength of a thermal sprayed coating is difficult to measure using a conventional pull-off test method. Scratch test is a potential alternative testing method. An adhesive and a cohesive bond strength of the coating can be measured by the pull-off test while the scratch test performed on the cross-section of the thermal sprayed coating can only demonstrate the cohesive bond strength of the coating. Nevertheless, it is still beneficial to perform the scratch testing on the cross-section of the coating for the sake of comparison thus providing an alternative to the pull-off test. The scratch test method can reduce testing time and cost in the long run due to a significant cost reduction in consumables and energy and time saving from the curing step of the glue used in the pull-off test. This research investigates the possibility of using the scratch test to measure the cohesive bond strength of Mo/NiCrBSi composite coating. The results from the pull-off test and the scratch test indicate that the cohesive bond strengths of the Mo composite coating show similar trend and that the cohesive bond strength are increased when increasing NiCrBSi content.

• 대한건축학회논문집:구조계
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• 제35권8호
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• pp.123-130
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• 2019

Recently, it is required to develop a monitoring technology that combines an FBG sensor as a means for continuously monitoring whether reinforcing effect of FRP is maintained on FRP reinforced structural members. However, most existing researches focus on the insertion of FBG sensors into bar-shaped FRPs, and there is insufficient study on the details strip-type FRPs combined with FBG sensors. Therefore, in this paper, it is studied to develop a reinforcement in which a FBG sensor is combined with a FRP strip. Especially, combination of FRP and FBG sensor. For this, a series of experiments were performed to find the adhesive strength of fiber-FRP-epoxy joints, the tensile strength of FBG sensor part with reflection-lattice, and the performance depending on the connection method of FRF and FBG sensor. As a result of the study, it was found that a minimum strength of $216.15N/mm^2$ is required for incorporating FBG sensors in FRP using epoxy. It is considered that the adhesion length of epoxy joints should be more than 50mm. When the FBG sensor is attached to the FRP strip as an epoxy, it is considered appropriate to use the complete attachment and the sensor non-attachment method.

• 한국건축시공학회:학술대회논문집
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• 한국건축시공학회 2021년도 봄 학술논문 발표대회
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• pp.14-15
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• 2021

Recently, the size of tiles used for bathroom walls in apartment houses is gradually increasing in size. The problem is that when these large-sized tiles are attached by the sticking method, due to the nature of the method, there is a concern about the stability of the attachment to the part (pupil) where the tile and the adhesive are not attached. The problem is serious as it leads to lawsuits in the outbreak court. In addition, it is urgent to verify the adhesion stability of the sticking method because secondary damage occurs due to a safety accident caused by the falling of the tile. Ministry of Land, Infrastructure and Transport [Investigation of defects in apartment houses, calculation of repair cost and defect determination criteria] ① The tile adhesion strength is 0.39N/mm² or more and ② It is specified to fill 80% or more of the base area of the tile backside, but this is currently trendy. It is considered that large-sized tiles need to be verified from multiple angles, and as part of that, we intend to verify the adhesion stability according to the area to be attached to large-sized tiles.

• Nuclear Engineering and Technology
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• 제55권12호
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• pp.4317-4328
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• 2023

To ensure the measuring accuracy of the wall temperature, the outer wall temperature measurement values by using three kinds of thermocouple welding methods were analyzed and evaluated in the paper, including single-point flush-mounted in the wall groove method, single-point insert-mounted in the wall groove, and outer surface direct welding method, based on the application of a tube-in-tube condensing heat exchanger. And the impacts of silver, tin, and thermal resistance adhesive as filling materials on wall temperature measurement were also investigated, and the results were compared to that obtained without filling materials. The results showed that the wall temperatures measured by the three welding methods were lower than the theoretically calculated value. And the wall temperature measured by the outer surface direct welding method was lowest under the same experimental conditions. The wall temperatures measured by single-point flush-mounted and insert-mounted in the wall groove methods were also affected by different welding filling materials. It was found that the greater the thermal resistance of filling materials, the smaller the heat loss. By analyzing the reasons for the low measured value of wall temperature, a new wall temperature measurement method was developed to improve the accuracy of the current measurement method. Meanwhile, the outer wall temperature measurement experiments of vertical and horizontal heat transfer tubes were carried out to validate and calibrate the improved outer wall temperature measurement method. The results showed that the average outer wall temperature deviation measured by the improved wall temperature measurement method ranged from - 0.82% to +2.29% for vertical tubes and - 4.75% to - 1.44% for horizontal tubes, and the improved measurement method had good measurement accuracy.

• 한국소성가공학회:학술대회논문집
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• 한국소성가공학회 2009년도 추계학술대회 논문집
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• pp.33-37
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• 2009

Finite-element methods are used to study non-adhesive, frictionless rough contact of elastic and plastic solids. Roughness on spherical surfaces is realized by self-affine fractal. True contact area between the rough surfaces and flat rigid surfaces increases with power law under external normal loads. The power exponent is sensitive to surface roughness as well as the curvature of spherical geometry. Surface contact pressures are analyzed and compared for the elastic and plastic solids. Distributions of local contact pressure are shown dependent on the surface roughness and the yield stress of plastic solids.

• International Journal of Concrete Structures and Materials
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• 제6권2호
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• pp.87-100
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• 2012

The process of selecting a repair material is a typical one of multi-criteria decision-making (MCDM) problems. In this study Analytical Hierarch Process was applied to solve this MCDM problem. Many factors affecting a process to select an optimal repair material can be classified into quantitative and qualitative requirements and this study handled only quantitative items. Quantitative requirements in the optimal selection model for repair material were divided into two parts, namely, the required chemical performance and the required physical performance. The former is composed of alkali-resistance, chloride permeability and electrical resistivity. The latter is composed of compressive strength, tensile strength, adhesive strength, drying shrinkage, elasticity and thermal expansion. The result of the study shows that this method is the useful and rational engineering approach in the problem concerning the selection of one out of many candidate repair materials even if this study was limited to repair material only for chloride-deteriorated concrete.

• 대한기계학회논문집A
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• 제29권2호
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• pp.220-227
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• 2005

In this study, stress-displacement analytic solutions are obtained by a shear lag modeling method constructed for the spliced joint area with a splicing gap in the fiber metal laminate (FML). This gap can be empty or be filled with an adhesive material of elastic modulus $E_a$. Two splicing types are considered for spliced shear models, one for spliced in the center metal layer, the other for spliced in the outer metal layer. It is shown that from the viewpoint of the load transfer efficiency and the avoidability of disbond generation due to the shear and axial stresses at the interface between metal layer and composite layer of the gap-front in the spliced area, the center spliced type (k=2) is much preferable to the outer spliced type (k=1).