• Title/Summary/Keyword: Additive

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Single and Dual Ligand Effects on Gene Expression Changes in Mouse Macrophage Cells

  • Choi Sang-Dun;Seo Jeong-Sun
    • Genomics & Informatics
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    • v.4 no.2
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    • pp.57-64
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    • 2006
  • We identified differentially expressed genes in RAW264.7 cells in response to single and double ligand treatments (LPS, $IFN{\gamma}$, 2MA, LPS plus $IFN{\gamma}$, and LPS plus 2MA). The majority of the regulated transcripts responded additively to dual ligand treatment. However, a significant fraction responded in a non-additive fashion. Several cytokines showing non-additive transcriptional responses to dual ligand treatment also showed non-additive protein production/secretion responses in separately performed experiments. Many of the genes with non-additive responses to LPS plus 2MA showed enhanced responses and encoded pro-inflammatory proteins. LPS plus $IFN{\gamma}$ appeared to induce both non-additive enhancement and non-additive attenuation of gene expression. The affected genes were associated with a variety of biological functions. These experiments reveal both dependent and independent regulatory pathways and point out the specific nature of the regulatory interactions.

Review of Recent Trends and Technology for Additive Manufacturing (적층제조기술 응용사례 및 최신기술동향)

  • Lee, Jaehyang;Park, Sung-Jun
    • Journal of Institute of Convergence Technology
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    • v.6 no.1
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    • pp.1-5
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    • 2016
  • Additive manufacturing is converting a digitally designed object into a tangible three dimensional solid using an additive process where materials are applied in successive layers with no or very limited material waste. It can be distinguished form traditional manufacturing which begins with a fixed amount of raw material and removes excess to arrive at the final product. Generally there are five stages to the additive manufacturing supply chain, namely materials, systems, software, application design and production. In this paper, recent market trends and technology about additive manufacturing based on supply chain are analyzed and reviewed.

Ferrous Chloride Pickling Bath A new process for pre-treatment of metals

  • Ericson, U.H.;Ericson, H.A.H.
    • Journal of the Korean institute of surface engineering
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    • v.32 no.3
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    • pp.219-223
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    • 1999
  • A new additive for semi-brightness finish in nickel electroplating, having a quarternary ammonium salt structure, has been developed in this study. The effectiveness of the new additive was tested in laboratory-scale eletroplating tests as well as in a full-scale factory plating line. An examination of the plated surface showed that the new additive is as good as the one produced by the most commonly used additive in the nickel plating industry. The plated surface was examined by SEM, EPMA, and Reflectance Spectroscopy, and was found to be compatible to the one obtained with commercial additives. The new additive has a shelf life comparable with those of other commercially available additives. The additive developed in this study has an excellent potential to be used commercially.

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Effect of Cow Manure and Saw Dust as the Additive Materials for Efficient Vermistabilization

  • Kim, Cbul;Son, Hee-Jeoog;Yoon, Tae-Kyung
    • Journal of Environmental Health Sciences
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    • v.33 no.6
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    • pp.488-492
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    • 2007
  • The influence of additive materials including saw dust and cow manure in the ripening of leather sludge for the efficient vermisabilization was studied. The ripening characteristics of the leather sludge, the growth of earthworms in the growth bed and the by-products like cast were observed according to the mixing ratio of additive materials. When the mixed leather sludge of which the additive materials contents were over 20% were ripened for 50 days, the values of ORP and alkalinity were changed to the favorable ranges for earthworms, the positive (+) and below 1,000 mg/l as $CaCO_3$, respectively. The velocity of ripening improving the characteristics of the leather sludge was faster in the sludge mixed with cow manure than saw dust. This results could also be verified from the monitoring of the states of earthworm growth using the survival rate, the increase rate of lifeweight and the hatching rate of earthworm cocoon in the their growth bed packed with the ripened sludge. The values of CEC in cast, the vermi-stabilized sludge, were increased with the mixing ratio of additive materials, but the content of heavy metals was drcreased by the dilution effect and accumulation in the earthworm body. Above results show that the leather sludge might be efficiently stabilized by earthworms through the ripening for 50 days using additive materials. Cow manure can be used as a good additive materials for leather sludge as much as saw dust, and the optimum content of additive materials in the well-ripened leather sludge was about 30%.

Effect of Oral Administration of DiakurTM (a Glucose and Electrolytes Additive) on Growth and Some Physiological Responses in Broilers Reared in a High Temperature Environment

  • Takahashi, Kazuaki;Akiba, Yukio
    • Asian-Australasian Journal of Animal Sciences
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    • v.15 no.9
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    • pp.1341-1347
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    • 2002
  • An experiment was conducted to determine effects of oral administration of $Diakur^{TM}$ (an additive of glucose and electrolytes for young calves) on growth performance and some physiological responses in male broilers reared in a high temperature. A 2 by 3 factorial arrangement test of 2 temperatures (24 and $36^{\circ}C$) and 3 levels of oral administration of the glucose and electrolytes additive, $Diakur^{TM}$, (0, 150 and 300 mg/day/100 gBW) were applied in the experiment. Male broiler chicks (2 weeks of age) were assigned to six groups and received dietary and temperature treatments for 7 days. The additive of glucose and electrolytes was suspended with water and intubated into crop twice a day (08:00 and 17:00). Oral administration of the additive prevented decreases in food intake and growth rates in broilers due to exposure of the hot environment. Oral administration of the additive also improved a lowered electrolyte ($Na^+$ + $K^+$ - $Cl^-$) balance in plasma, low mitogenic response of blood mononuclear cell and an increase in glucose concentration due to exposure to the high environmental temperature. Oral administration of the additive increased rectal temperature regardless of environmental temperatures. On the other hand, blood pH, $pCO_2$ and $HCO_3$ - concentration, and plasma creatine kinase activity were not affected by the oral administration. The results suggested that oral administration of the glucose and electrolytes additive, $Diakur^{TM}$ during heat stress did not only prevent decrease in growth performance, but also normalized some physiological and immunological responses in male broilers.

Evaluation of Warm-Recycled Asphalt Mixtures using Polyethylene Wax-Based Additive (중온화 첨가제를 사용한 중온 재생 아스팔트 혼합물 평가)

  • Lee, Jin Wook;Lee, Moon Sup;Kim, Yong Joo;Cho, Dong Woo;Kwon, Soo Ahn
    • International Journal of Highway Engineering
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    • v.15 no.4
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    • pp.43-51
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    • 2013
  • PURPOSES : The main purposes of this study are to examine the influences of polyethylene wax-based WMA additive on the optimum asphalt content of warm-recycled asphalt mixture based on the Marshall mix design and to evaluate performance of warm-recycled asphalt mixture containing 30% RAP with polyethylene wax-based WMA additive. METHODS: Physical and rheological properties of the residual asphalt were evaluated in terms of penetration, softening point, ductility and performance grade (PG) in order to examine the effects of polyethylene wax-based WMA additive on the residual asphalt. Also, To evaluate performance characteristics of the warm-recycled asphalt mixtures using polyethylene wax-based WMA additive along with a control hot-recycled asphalt mixture, indirect tensile strength test, modified Lottman test, dynamic immersion test, wheel tracking test and dynamic modulus test were conduced in the laboratory. RESULTS : Based on the limited laboratory test results, polyethylene wax-based WMA additive is effective to decrease mixing and compacting temperatures without compromising the volumetric characteristics of warm-recycled asphalt mixtures compared to hot-recycled asphalt mixture. Also, it doesn't affect the optimum asphalt content on recycled-asphalt mixture. All performance test results show that the performance of warm-recycled asphalt mixture using polyethylene wax-based WMA additive is similar to that of a control hot-recycled asphalt mixture. CONCLUSIONS: Overall, the performance of warm-recycled asphalt mixture using polyethylene wax-based WMA additive is comparable to hot-recycled asphalt mixture.

A Study on Manufacturing Standards for Solid Type Fuel Additive (고체 연료첨가제 제조 기준 설정을 위한 연구)

  • Lee, Eui-Sang;Oh, Se-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.10 no.6
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    • pp.1292-1297
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    • 2009
  • This study was performed to investigate solubility, dissolution rate and ash content of solid type fuel additive in gasoline and diesel in order to set up manufacturing standards. From the results, the unfiltered impurities were increased when the fuel additive was added on gasoline and diesel. Also, the unfiltered fuel additive was decreased with respect to increasing the pore size of the filter paper. When one gram of the fuel additive was dissolved in one liter of gasoline at room temperature, the best dissolution rate was about 2 hours. But, almost nothing was dissolved in diesel during 72 hours at $20^{\circ}C$ below zero. At the experiment of ash content, the gasoline which the fuel additive was melted in was showing 28 times more ash content than that was not including the fuel additive. Therefore, it seemed that almost all of ash content was caused by the fuel additive.

Investigation to Metal 3D Printing Additive Manufacturing (AM) Process Simulation Technology (II) (금속 3D 프린팅 적층제조(AM) 공정 시뮬레이션 기술에 관한 고찰(II))

  • Kim, Yong Seok;Choi, Seong Woong;Yang, Soon Yong
    • Journal of Drive and Control
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    • v.16 no.3
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    • pp.51-58
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    • 2019
  • The objective of this study was to investigate a simulation technology for the AM field based on ANSYS Inc.. The introduction of metal 3D printing AM process, and the examining of the present status of AM process simulation software, and the AM process simulation processor were done in the previous study (part 1). This present study (part 2) examined the use of the AM process simulation processor, presented in Part 1, through direct execution of Topology Optimization, Ansys Workbench, Additive Print and Additive Science. Topology Optimization can optimize additive geometry to reduce mass while maintaining strength for AM products. This can reduce the amount of material required for additive and significantly reduce additive build time. Ansys Workbench and Additive Print simulate the build process in the AM process and optimize various process variables (printing parameters and supporter composition), which will enable the AM to predict the problems that may occur during the build process, and can also be used to predict and correct deformations in geometry. Additive Science can simulate the material to find the material characteristic before the AM process simulation or build-up. This can be done by combining specimen preparation, measurement, and simulation for material measurements to find the exact material characteristics. This study will enable the understanding of the general process of AM simulation more easily. Furthermore, it will be of great help to a reader who wants to experience and appreciate AM simulation for the first time.

A study on Improving the Dyeability of BTCA treated Cotton Fabrics Containing Nitrogenous Cationic Additives (BTCA처리 면직물의 질소계양이온화제 첨가에 의한 염색성 향상에 관한 연구)

  • 박은경;유효선
    • Journal of the Korean Society of Clothing and Textiles
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    • v.24 no.6
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    • pp.819-827
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    • 2000
  • The purpose of this study is to produce cotton fabric having improved dyeability and colorfastness as well as retaining the desirable durable press property. When cotton fabric was treated with additives, nitrogen content was increased as the additive concentration was increased. DP ratings and wrinkle recovery properties of BTCA treated cotton fabrics were greatly increased. But DP rating was lowered slightly by adding additives and wrinkle recovery property was decreased with the increase of additive concentration. Tensile strength was decreased by BTCA treatment but increased as additive concentration was increased. Various BTCA/additive treatments produced great affinity for reactive and acid dyes when dyebaths were adjusted at pH 3. It was showed that dyeability was increased as additive concentration was increased. The most effective additive for improving the dyeing properties of the crosslinked cotton was TEAㆍHCl. In case of reactive dye, there was almost no improvement on the dyeability of finished cotton by adding salt. Color fastness to washing and light of finished and dyed cotton were low except for the washfastness of reactive dye. Dyeing the BTCA/additive treated cotton fabrics with reactive dye had no effect on the physical properties.

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Effects of Additive Composition and Content on Sintered Density and Compressive Strength of Cordierite Ceramics (첨가제의 조성과 함량이 코디어라이트 세라믹스의 소결밀도와 압축강도에 미치는 영향)

  • Jang, Doo-Hee;Lim, Kwang-Young;Kim, Young-Wook
    • Journal of the Korean Ceramic Society
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    • v.44 no.4 s.299
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    • pp.230-234
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    • 2007
  • Cordierite ceramics were fabricated via a reaction sintering process using ceramics-filled polysiloxane as a precursor for cordierite ceramics. In this study, the effects of the additive composition, additive content, and sintering temperature on the sintered density and compressive strength of cordierite ceramics have been investigated The sintered densities of reaction-sintered cordierite ceramics containing $TiO_2$ as an additive were insensitive to the additive composition, additive content, and sintering temperature and ranged from $1.92g/cm^3\;to\;2.06g/cm^3$. In contrast, the cordierite ceramics containing $Y_2O_3$ showed a maximal density of $2.21g/cm^3$ at 5 wt% addition and at a sintering temperature of $1400^{\circ}C$. The compressive strength of cordierite ceramics showed the same tendency with the density. Typical compressive strength of cordierite ceramics containing 5 wt% $Y_2O_3$ as a sintering additive and sintered at $1400^{\circ}C\;was\;{\sim}480MPa$.