• The Korean Journal of Rehabilitation Nursing
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• v.6 no.2
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• pp.213-225
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• 2003

The purpose of this study is to develop and evaluate the health promotion program to increase the functional status of the in-house stroke patients. The subjects for the experiment are 38 in-house stroke patients in a health center and welfare centers suffering from hemiplegia. The experimental group consists of 19 stroke patients and the control group consists of another 19 stroke patients. The program was applied to the experimental group for 8 weeks. The subjects were given health education at the first week. At the second and the fifth week they were given counselling on health by home visit. At the third, the fourth, the sixth and the seventh week they were interviewed by phone about health, and at the last week they shared their experiences through group meeting. The results of the study are as follows: 1. The degree of ADL in the experimental group increased significantly, compared with that of the control group. 2. In the experimental group the degree of Range of Motion in shoulder abduction, elbow flexion, hip flexion and ankle dorsiflexion increased significantly, compared with that of the control group. 3. In the experimental group the degree of muscle strength in elbow flexion, knee extension, and ankle dorsiflexion increased significantly, compared with that of the control group. 4. Systolic pressure, diastolic pressure in the experimental group decreased significantly, compared with that the control group. 5. HWR in the experimental group didn't decreased significantly, compared with that the control group. 6. The degree of depression in the experimental group decreased significantly, compared with that the control group. 7. The degree of social adaptation in the experimental group increased significantly, compared with that the control group. The results above show that the health promotion program for this study was effective in promoting the performance of lifestyle for health improvement of the in-house stroke patients. Therefore, it is considered that the program can be used as an efficient nursing intervention for the in-house stroke patients who need continuous health-improving behaviors.

• Journal of Periodontal and Implant Science
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• v.30 no.2
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• pp.359-374
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• 2000

Cyclosporine A(CsA) is a widely used immunosuppressant for transplant patients and is also used for the treatment of a wide variety of systemic diseases with immunologic disorders. However, its use is frequently limited because of complications such as nephrotoxicity or gingival hyperplasia. Although several hypotheses have been postulated for CsA-induced gingival hyperplasia, i.e. various cytokine effects of inflammatory cells, existence of plaque or CsA itself, but its pathogenesis is still unclear. For experimental chronic CsA toxicity, salt depletion has been shown to increased susceptibility of rodents to the effects of CsA, and this maneuver facilitates production of arteriolopathy and interstitial fibrosis in kidney that mimic the changes found in human. The purpose of this study was to evaluate pathogenesis of CsA-induced gingival hyperplasia by comparing changes between CsA administration groups of normal standard diet and those of low salt diet group. Specific pathogen-free, 20 to 25 days old(120 to 150 g), male Fisher-344 rats(KIST, Korea), 120 to 150g of body weight, were assigned to four groups of six animals each after one week of adaptation period for powder food. Group 1 received olive oil($300{\mu}l/g\;of\;diet$) with normal standard diet(0.4% of sodium)(NSD). Group 2 received CsA(Cypol-N, Jonggundang, Korea; $300{\mu}g/g\;of\;diet$) with normal standard diet(NSD+CsA). Group 3 received same amount of olive oil with low salt diet(0.05 % of sodium, Teklad Premier, U.S.A.)(LSD). Group 4 received same dose of CsA with low salt diet(LSD+CsA). Rats were pair fed and were sacrificed after six weeks. Renal histologic lesions associated with CsA, consisted of cortical interstitial fibrosis, tubular atrophy and hyalinization of arterioles and the impairment of renal function including increase of serum creatinine and decrease of glomerular filtration rate was more severe in low salt diet group. These were proved as the results of activated of renin-angiotensin system in the kidney by low salt condition. Meanwhile the degree of gingival hyperplasia at incisor and molar tooth was less severe in low salt diet group compared with normal sodium diet group. Hyperplastic gingiva showed mild epithelial hyperplasia and expanded underlyng stroma which consisted of matrix increasement, capillary proliferation and dilatation. While the number and the activation of fibroblasts were increased, inflammatory cells were rare in the stroma. The immunohistochemistry for TGF-${\beta}_1$ in the kidney and gingiva revealed stronger positive in LSD+CsA in kidney but in gingiva of NSD+CsA. These results suggested followings; Gingival hyperplasia can be developed without inflammatory cells infiltration and seemed not induced by CsA by itself. The major role for gingival hyperplasia by CsA would be the secondary effect of TGF-${\beta}$, which maybe upregulated by CsA administration. Low salt diet can attenuate this hyperplasia perhaps by decreasing the activation of $TGF-{\beta}$.

• The Journal of Korean Physical Therapy
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• v.15 no.3
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• pp.16-44
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• 2003

Skeletal muscle regeneration is a vital process for various muscle myopathies and muscular adaptation to physiological overload. Angiogenesis is the key event in the process of muscle regeneration, and vascular endothelial growth factor(VEGF) plays an important role in it. The purpose of this study was to evaluate the effect of GaAlAs(830nm) laser and immunoreactivity of VEGF on angiogenesis after muscle contusion injury. Muscle contusion injury was induced in the triceps surae muscle by dropping a metal bead(31.4g). GaAlAs laser irradiation(power 20 mW, frequency 2000 Hz, treatment time 15 min) was applied directly to the skin of injured muscle daily for seven days. The experimental group I was irradiated immediately by laser after injury, whereas the experimental group II was irradiated after 1 day of injury. The control group was non-irradiated. The results of this study were as follows. 1. In morphological observation, there were no significant changes in experimental and control groups for 7 days. At 3 days, however, the splited muscle fibers were observed in experimental groups, and the muscle atrophy and granular tissue viewed at 7 days in control group. 2. The VEGF was expressed in muscle fiber that located in the interspace between gastrocnemius and soleus muscles. As the time coursed, the immunoreactivity of VEGF also seemed to be strong in the individual muscle fibers. 3. The experimental group I & II showed higher immunoreactivity of VEGF than control group(p<0.05). Then, the experimental group I showed higher than group II especially(p<0.05). These data suggest GaAlAs semiconduct diode laser irradiation(830nm) enhanced angiogenesis in the skeletal muscle induced contusion injury, and immediate laser irradiation after injury promoted the angiogenesis greatly than after 1 day of injury.

• Korean journal of food and cookery science
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• v.30 no.4
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• pp.369-377
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• 2014

Obesity increases oxidative stress, which could contribute to the development of insulin resistance and hyperglycemia. The purpose of this study was to investigate the hypoglycemic and antioxidant effect of sanchae-namul (SN) in mice with diet-induced obesity. Five-week-old male C57BL/6J mice were fed a basal or high-fat and high-sucrose (HFHS) diet with or without 3% freeze-dried SN powder composed of chamnamul, daraesoon, miyeokchwi, bangpung namul, and samnamul for 12 weeks after a 1-week adaptation. After sacrifice, serum glucose and insulin were measured and the homeostasis model assessment for insulin resistance (HOMA-IR) was determined as well. Hepatic lipid peroxidation, glutathione (GSH), and activities of the antioxidant enzymes were determined. SN given at 3% of the total diet did not significantly influence body weight and food intake in mice fed the HFHS diet. Serum glucose and insulin levels, as well as HOMA-IR values, were significantly lower in the SN group than those in the HFHS group. Thiobarbituric acid reactive substances (TBARS) levels in the liver were decreased significantly in the SN group compared with those in the HFHS group. SN significantly increased the GSH levels and the activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) in the liver compared with those in the HFHS group. Overall, these findings suggest that SN may be useful in alleviating insulin resistance and hyperglycemia in mice fed HFHS diet; further, the improvement of insulin resistance could partly occur by reducing the oxidative stress.

• Journal of Korean society of Dental Hygiene
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• v.10 no.4
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• pp.627-633
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• 2010

Objectives : The purpose of this study was to compare and analyse periodontal terminology of 16 dental hygiene textbooks including periodontology, dental prophylaxis for the standardization. Methods : 16 kinds of major publications were classified into the following criteria. - the standardization of translation, orthography, classification Results : 1. There are twelve cases, all told, of words with same origin used as different explanation and interpretation. Mucogingival Junction is most translated as '치은점막 경계' with high percentage of 53.8%, while Probe is translated as '치주낭 측정기' with 41.7% and Acquired Pellicle is translated as '획득피막' with 57.1%. In addition, Stippling is interpreted as '점몰' with high percentage of 70%, and Supine Position is interpreted as '수평자세' or '앙와위' with 33.3%. Yet, Pen Grasp is explained differently in all five books, whereas Modified Pen Grasp is explained as '변형 연필 잡기법' with 57.1%. The rest, Palm Thumb Grasp and Adaptation, have different interpretation in books, requiring unified interpretation of terms. 2. There are two cases of loanwords expressed according to orthography. Implant is expressed as '임플란트'(87.5%) and '임프란트'(12.5%). Scaling is expressed as '스켈링'(40.0%) and '스케일링'(60.0%). 3. There are four cases of same terms classified in a different way. Classification of 'Probing시 압력' and '치주인대섬유군' concurs only 50.0% in six books. '치석제거 시술자의 위치' is classified differently in all six books, while '정상치은 열구 깊이' concurred 45.5% in books. Conclusions : In conclusion, related academic majors and writers should provide cohesive explanation and interpretation of terms for unification of terminology in the field of periodontics as well as higher level of understanding and learning opportunities for students. Furthermore, description of all terms should be reviewed and analyzed comprehensively based on existing classification criteria in order to provide best standard explanation.

• The Journal of Korean Academy of Prosthodontics
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• v.43 no.4
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• pp.438-452
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• 2005

Statement of problem: The use of Ceromer is increasing in dentistry. But, the research of Ceromer has not been conducted much. Purpose : This study was to evaluate the marginal fidelity and internal adaptation according to marginal position. Materials and Methods: In this study 60 resin crowns were fabricated. The measurements of the marginal fidelity were carried out using stereomicroscope $SZ-40^{(R)}$ (Olympus, Japan) and the measurements of fracture strength were done using Instron $8871^{(R)}$ (Instron Co., U.S.A.) at a cross head speed of 1mm/min. All of the measurements were statistically analyzed by ANOVA test, multiple range test and Weibull analysis. Statistical significance was set in advance at the probability level of less than 0.05. All of the measurements were analyzed with Window $SPSS^{(R)}$ Version 10.0 soft ware for the personal computer. Results : 1. There were no statistical differences of the marginal fidelity between $Targis^{(R)}$ and $Tescera^{(R)}$, but difference between these two and $BelleGlass^{(R)}$ according to materials. 2. There were no statistical differences of the marginal fidelity between no fiber group and fiber group. There were no interactions between each maerial and with/without fiber group in the marginal fidelity 3. There were statistical differences of the fracture strength between $Tescera^{(R)}$ and $BelleGlass^{(R)}$ but no statistical differences of the fracture strength between $Targis^{(R)}$ and $Tescera^{(R)}$, $Targis^{(R)}$ and $BelleGlass^{(R)}$ according to materials. 4 There were statistical differences of the fracture strength between no fiber group and fiber group. There were no interactions between each material and with/without fiber group in the fracture strength. 5. When comparing the fracture surface, no fiber group showed the resin which were fractured at the labial surface and separated from the adhesion surface. In fiber group, the fractures took a place in resin compartments. Conclusion. The marginal fidelity and the fracture strength were clinically acceptable. From these results, $Targis^{(R)}$ and $Tescera^{(R)}$ were superior than $BelleGlass^{(R)}$ in the marginal fidelity But, when applying these resin crowns in clinic, more careful consideration is needed and further study is recommended.

• Asian-Australasian Journal of Animal Sciences
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• v.32 no.8
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• pp.1145-1152
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• 2019

Objective: Mulberry (Morus alba L.) is a cultivated shrub grown widely in the sub-tropical and tropical areas. It has been shown that mulberry leaf contains high levels of protein while having polyphenols as phytonutrients. Therefore, it is important to conduct an experiment to assess potential toxic level from mulberry on behavior, blood hematological and coagulation parameter using Sprague-Dawley (SD) rats. Methods: Both male and female SD rats were given an intragastric administration of respective treatments of mulberry leaf intakes (control, low and high levels). Parameters of feed intake, hematological and coagulation of blood parameters, as well as liveweight changes were taken during the 7 d of adaptation, 28 d of treatment exposure, and 14 d of recovery periods, respectively. All treatment data were statistically analyzed using analysis of variance of SPSS17.0 for Windows Statistical Software following the Randomized complete block design with sex as a block. Results: Most of the parameters of the physical symptoms of the SD rats, were not significantly different (p>0.05) when compared with that of the control group. Those which remain unchanged in each dose group were, body weight (BW) gain, feed intake, the hematology and coagulation indexes. Although, there were a few individual indicators that were abnormal, but the overall physiological appearance of the rats were normal. Conclusion: Results under this experiment revealed that most hematological and coagulation parameters of the SD rats in both male and female were normal, although the weight gain of female rats in high-dose group was significantly reduced than those of the male rats. Under this study, the use of mulberry leaf up to 2 g/kg BW did not result in abnormal phenomenon in the SD rats. These findings would offer useful information for further in vivo feeding trials in animals to extensively use of mulberry leaf to improve animal production, particularly in P.R. China.

• Phonetics and Speech Sciences
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• v.10 no.3
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• pp.1-8
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• 2018

The vowel /o/ in Seoul Korean has been undergoing a sound change by altering the acoustic weighting of F2 and F1. Studies documented that this on-going change redefined the nature of a /o/-/u/ contrast as F2 differences rather than as F1 differences. The current study examined two cognitive factors namely executive function capacity (EF) and autistic traits, in terms of their roles in explaining who in speech community would adapt new acoustic forms of the target vowels, and who would retain the old forms. The participants, 55 college students speaking Seoul Korean, produced /o/ and /u/ vowels in isolated words; and completed three EF tasks (Digit N-Back, Stroop, and Trail-Making Task), and an Autism screening questionnaire. The relationships between speakers' cognitive task scores and their utilizations of F1 and F2 were analyzed using a series of correlation tests. Results yielded a meaningful relationship in participants' EF scores interacting with gender. Among the females, speakers with higher EF scores were better at retaining F1, which is a less informative cue for females since they utilized F2 more than they did F1 in realizing /o/ and /u/. In contrast, better EF control among male speakers was associated with more use of the new cue (F2) where males still utilized F1 as much as F2 in the production of /o/ and /u/ vowels. Taken together, individual differences in acoustic realization can be explained by individuals' cognitive abilities, and their progress in the sound change further predicts that cognitive ability influences the utilization of acoustic information which is non-primary to the speaker.

• Korean Journal of Schizophrenia Research
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• v.22 no.2
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• pp.34-41
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• 2019

Objectives: This study was performed to examine the effects of the public attention to 'crime of schizophrenia' on the use of mental health services in patients with schizophrenia using big data analysis. Methods: Data on the frequency of internet searches for 'crime of schizophrenia' and the patterns of mental health service utilization by patients with schizophrenia spectrum disorders by month were collected from Naver big data and the Health Insurance Review and Assessment Services in Korea, respectively. Their correlations in the same and following month for lagged effect were examined. Results: The number of outpatients correlated negatively with public attention to 'crime of schizophrenia' in the same month. The lagged relationship between public attention and the number of admissions in psychiatric wards was also found. In terms of sex differences, the use of outpatient services among female patients correlated negatively with public attention in the same month while the number of male patients' admissions in both same and following month correlated positively with public attention. Conclusion: These findings suggested that public attention to 'crime of schizophrenia' could negatively affect illness behavior in patients with schizophrenia.

• Journal of Music and Human Behavior
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• v.15 no.1
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• pp.51-68
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• 2018

The purpose of this study was to examine the use of music by international college students in Korea. A questionnaire was administered to foreign college students. The questionnaire was composed of 25 items regarding use of music, the purpose of music use, and demographic information. A total of 150 questionnaires were distributed, and 81 questionnaires were returned. Incomplete questionnaires were excluded, and the remaining 69 questionnaires were analyzed. The results of this study were as follows. First, international students in Korea preferred listening to music over playing instruments or singing and mostly listened to popular music in their dormitory alone. They mostly listened to popular songs with love related themes and preferred music from their own country over Korean music. Second, in terms of the purpose behind music use, comfort was the reason reported most frequently, followed by mood change, enjoyment, sense of belonging, and sense of achievement. Third, there were no significant differences in use of music depending on individual factors (e.g., gender, length of residence in Korea, length of previous music education), but significant differences were found for using music for the purpose of mood change and sense of belonging based on respondents' length of residence in Korea. The results of this study may contribute to the development of musical programs for cultural adaptation and psycho-emotional support for international students in Korea.