• 대한물리치료과학회지
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• 제4권2호
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• pp.405-419
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• 1997

This research has been conducted to provide the spinal cord injured patients with comprehensive necessity of and backup data for their rehabilitation in the community and make the aware of importance of overall community support to patients. The data was collected through questionnaire made to 83 patients charged to general hospital in Jeonbuk Province between 1 and 31 March 1997 to analyse the patients ability on activities of daily living through the research on general characteristics and Modified Barthel Index(MBI). As a result the outcome of the research was as follows : 1. Sexual distribution represented that 57 male (68.7%) and 26 female(31.3%) and in the age distribution majority group was 36 thirties (43.4 %) most active in social activities. 2. Analysis on occupation of patients showed majority group was in technicians, 21 people representing 25.4 % and the major cause of injury was traffic accident, 45people representing 54.2%, fall down, 17 people representing 20.5% and industrial accident, 13 people representing 15.7%, respectively. 3. In the multiple choice questionnaire on complications, the rate of appealing pain was highest and spasticity, pressure sore, contracture, depression which restrict the patients from activities of daily living ability were also appeared. 4. The theoretical points in MBI Should lie between 1 and 115 and the average point be 58 but the average point of the MBI among 83 patients was 63. 5. The MBI point by the level of injured represented statistically critical difference(P<0.001) and the MBI points tested by Duncan's Multiple Area Testing in lumbar(80.1) and in thoracic (65.8) represented critically higher than the one in cervical(42.5). 6. In the distribution of the method of Urination after spine injury, the intermittent catheterization represented highest numbar of 34(41.1 %). Testing by Duncan's Multiple Area Testing, as we found the critical difference in the analysis on MBI points(P<0.001), the point in independent self voiding patients ($90.87{\pm}29.34$) was higher than the one in other self voiding patients(P<0.05). 7. In th category of social activities after spine injury, the number of people classified in others, 41 people representing 49.5% was highest and in the MBI points of the spinal cord injured people in religious activity, hobby activity, private club, occupation was critically higher than the people classified in miscellancous(P<0.01) who are the spinal cord injured people and mostly depend on their family's assistance at home in their daily activities.

• Journal of Preventive Medicine and Public Health
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• 제27권1호
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• pp.59-73
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• 1994

The purpose of this study is to experiments the environmental conditions and the adaption of the human body in the vinyl house. The study was done in spring and winter and experimental clothes were used working clothes in the vinyl house. The results are as follows. 1. Environmental Conditions In the spring season, the indoor air temperature was $27.4{\pm}3.7^{\circ}C$ and the outdoor air temperature was $14.4{\pm}2.7^{\circ}C$. In the winter season, the indoor air temperature was $18.3{\pm}4.8^{\circ}C$ and the outdoor air temperature was $7.6{\pm}2.5^{\circ}C$ on the average. 2. Skin Temperature In the spring season, the mean skin temperatures indoor and outdoor were $33.81{\pm}0.7^{\circ}C\;and\;31.57{\pm}0.8^{\circ}C$ respectively, a difference of $2.24^{\circ}C$. In the winter season, they were $31.95{\pm}1.93^{\circ}C\;and\;29.86{\pm}0.55^{\circ}C$ respectively, a difference of $2.09^{\circ}C$. 3. Clothing Climate In the spring season, the temperature and humidity in the inner layer of clothing were $34.77{\pm}0.80^{\circ}C\;and\;70.75{\pm}1.65%$ indoor, $31.9{\pm}0.52^{\circ}C\;and\;51.9{\pm}3.70%$ outdoor respectively. In the winter season, those were $32.52{\pm}1.04^{\circ}C\;and\;64.65{\pm}3.68%$ indoor, $30.27{\pm}0.96^{\circ}C\;and\;45.07{\pm}2.68%$ outdoor respectively. 4. Physiological Factors Body temperature increased slightly and the pulse rate also rises, but blood pressure decreased a little with the rise of environmental temperature both in the spring and winter seasons. 5. Psychological Factors Thermal sensation in the spring season was expressed as 'slightly warm' or 'warm' indoor and as 'neutral' in the open air, while in the winter it was expressed as 'neutral' or 'slightly warm' outdoor the house and as 'cold' in the open air. Comfort sensation was characterized as 'uncomfortable' or 'slightly uncomfortable' indoor both in the spring and winter seasons, but in the open air it was characterized as 'comfortable' in the spring and as 'slightly uncomfortable' in the winter.

• 대한치과교정학회지
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• 제30권2호
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• pp.197-204
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• 2000

본 연구에서는 인체 골종양에서 유래한 G292세포를 이용하여 압력으로 세포막을 신장(stretch)시켰을 때 $K^+$통로의 전기적 찰성 변화를 연구하였다. 배양된 세포에서 유골전극을 이용하여 세포막 내측이 유리전극의 외부로 향하도록 inside-out patch를 얻어 단일이온통로전류를 막전압고정법 (patch clamp recording)으로 기록하였다. G292세포의 세포막 내외에 140 mM KCl 용액이 있는 상태에서 유리전극내 전압을 -80 mV로 고정했을 때 전도성이 $270\pm27\;pS,\;113\pm12\;pS,\;48\pm8\;pS$인 3가지 종류의 $K^+$통로를 관찰하였다. 전도성이 낮은 48 pS의 $K^+$통로는 모든 세포막에서 관찰하였으며 270 pS 및 113 pS의 $K^+$ 통로는 일부 세포에서만 관찰하였다. 48 pS의 $K^+$통로는 세포막 외측에 음의 전압을 가하면 활성화되고 양의 전압을 가하면 활성화되지 않는 외향성 정류특성을 보였다. 세포막 외측에 음압을 가하면 48 pS의 $K^+$통로는 활성화되었으며 이온 통로가 열리는 확률($P_{open}$)이 가하는 압력에 비례하여 증가하였다. 이러한 결과는 G292세포주에 3가지 종류의 $K^+$통로가 존재하며 전도성이 낮은 48 pS의 $K^+$통로만이 세포막 신장에 의하여 직접적으로 활성화되는 특성을 보였다. 이러한 $K^+$ 통로의 활성화는 세포가 기계적 자극을 받아 세포막이 신장되면 세포막전압을 과분극시키며 조골세포에서 기계적 감수기로서의 기능을 수행하여 조골세포의 골개조에 관여할 것으로 추측된다.순에서는 수술 후 잉여 연조직에 의한 두께의 증가가 나타나고 상순에서는 구륜근에 의한 장력에 의해 상순의 두께가 감소하였다가 보정 기간 후 새로운 악골 위치로 적응하는 것으로 생각된다.다. 5. II급고무줄과 수직고무줄 적용 시를 비교해 보면 수직고무줄 장착시 전치부 치근막에 인장력이 더 넓게, 그 크기는 더 작게 나타났다. 반면에 구치부 치근막에 나타나는 응력의 분포와 크기는 별 차이를 보이지 않았다. 5. 전치부 치근막 인장부위에서 인장력은 견치에서 제일 컸다.상적 제1대구치간 치열궁 폭경의 예측이 1 mm의 오차한계 이내로 예측된 경우는 Cha 들의 예측식이 $40\%$ 로 가장 높으며, Pont와 Schmuth의 예측식은 각각 $29\%$와 $13\%$ 이었다. 이상의 결과는 상악 절치의 근원심 폭경의 합으로부터 이상적 제1소구치간 치열궁 폭경 및 제1대구치간 치열궁 폭경을 예측하는 것은 임상적 신뢰성이 낮을 것임을 시사한다.교정력을 효과적으로 전체 치열로 전달할 수 있는 독특한 기계적 특성을 지니고 있는 것으로 생각된다..7. 구순 반흔 제거수술시기로는 4-6세군 ($27.5\%$), 6-8세군 ($19.6\%$), 2-4세군 ($13.7\%$)이 $60\%$이상을 차지하여 초등학교 취학 전에 구순의 반흔을 제거하려 함을 알 수 있었다. 8. 비변형 교정수술시기로는 0-2세군 ($7.1\%$), 2-4세군 ($14.3\%$), 4-6세군 ($21.4\%$), 6-8세군 ($14.3\%$)으로 초등학교 취학이전이 $57.1\%$로서 최근의 조기 치료경향을 반영하는 것으로 보인다.

• Applied Biological Chemistry
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• 제42권4호
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• pp.293-297
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• 1999

Escherichia coli의 중요한 sugar 흡수 system인 Phosphoenolpyruvate. carbohydrate phosphotransferase system(PTS)의 주요 구성 enzyme을 만드는 pts operon에는 여러 개의 promoter가 존재하여 어느 환경에서도 적절한 정도의 PTS 활성을 유지하도록 한다. E. coli pts operon의 P1 promoter transcription이 in vitro와 in vivo에서 차이가 나는 원인을 밝히기 위하여 pts promoter activity에 영향을 줄 수도 있는 pts P0 Promoter의 1kbp upstream에서부터 P0와 P1 promoter까지 transcription vector에 cloning하여 in vitro transcription assay를 한 결과, pts promoter의 upstream DNA가 pts P1 promoter의 in vitro transcription에 미치는 영향이 없음을 알 수 있었다. 여러 가지 PTS sugar들을 이용하여 in vivo에서 이들 sugar 들이 pts transcription에 미치는 영향을 cAMP농도 변화와 비교 조사한 바, glucose존재 하에 자랄 때보다 CAMP농도가 높은 mannose나 mannitol 존재 하에 bacteria가 자랄 때 P1b transcription은 증가하나 P0 transcription은 glucose존재 하에 자랄 때 더 높은 결과를 보였다. 이 결과는 P0에 glucose에 의해 induction되는 repressor가 존재하고, P1 에는 glucose. mannose, mannitol에 의해 공통적으로 induction되는 제 2의 repressor가 존재할 것이라는 가능성을 보여주는 것이다.

• 한국환경과학회지
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• 제19권9호
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• pp.1137-1142
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• 2010

This study proposes a guideline of a green roof system suitable for the local environment by verifying the growth of Zoysia japonica in a shallow, extensive, green roof system under rainfed condition. The experimental soil substrates into which excellent drought tolerance and creeping Z. japonica was planted were made with different soil thicknesses(15cm, 25cm) and soil mixing ratios(SL, $P_7P_1L_2$, $P_6P_2L_2$, $P_5P_3L_2$, $P_4P_4L_2$). The plant height, green coverage ratio, fresh weight, dry weight and chlorophyll contents of Z. japonica were investigated. For the soil thickness of 15cm, the plant height of Z. japonica was significantly as affected by the soil mixing ratio and it was shown in the order SL= $P_4P_4L_2$ < $P_7P_1L_2$ = $P_5P_3L_2$ < $P_6P_2L_2$. For the soil thickness of 25cm, the plant height was increased in order to SL < $P_7P_1L_2$, $P_6P_2L_2$, $P_5P_3L_2$ < $P_4P_4L_2$. The green coverage ratio was not observed by soil the mixing ratio or soil thickness. However, the green coverage ratio was 86~90% with a good coverage rate overall. The chlorophyll contents of Z. japonica were not significantly affected by the soil mixing ratio in the soil thickness of 15cm, but were higher in the natural soil than in the artificial soil at 25cm soil thickness. The fresh weight and dry weight of Zoysia japonica were heavier in the 25cm thickness than in the 15cm thickness and in the artificial soil mixture than in the natural soil. The result indicated that the growth of Zoysia japonica was more effective in the 25cm soil thickness with artificial soil than in the 15cm soil thickness with natural soil in the green roof system under rainfed condition.

• The Korean Journal of Physiology and Pharmacology
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• 제11권1호
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• pp.1-7
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• 2007

Altered environmental gravity, including both hypo- and hypergravity, may result in space adaptation syndrome. To explore the characteristics of this adaptive plasticity, the expression of immediate early gene c-fos mRNA in the vestibular related tissues following an exposure to hypergravity stimulus was determined in rats. The animals were subjected to a force of 2 g (twice earth's gravity) for 1, 3, or 12 h, and were examined poststimulus at 0, 2, 6, 12, and 24 h. RT-PCR (reverse transcription polymerase chain reaction) and real-time quantitative RT-PCR were adopted to analyze temporal changes in the expression of c-fos mRNA. The hypergravity stimulus increased the expression of c-fos mRNA in the vestibular ganglion, medial vestibular nucleus, inferior vestibular nucleus, hippocampus, cerebellum, and cortex. The peak expression occurred at 0 h poststimulation in animals stimulated with hypergravity for 1 h, and at 6 h poststimulus in those stimulated for 3 h. In contrast, those stimulated for 12 h exhibited dual peaks at 0 and 12 h poststimulus. Bilateral labyrinthectomy markedly attenuated the degree of c-fos mRNA expression. Glutamate receptor antagonist also dramatically attenuated the degree of c-fos mRNA expression. These results indicate that expression of c-fos mRNA in response to hypergravity occurs in the vestibular related tissues of the central nervous system, in which peripheral vestibular receptors and glutamate receptors play an important role. The temporal pattern of c-fos mRNA expression depended on the duration of the hypergravity stimulus.

• Journal of Microbiology and Biotechnology
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• 제25권2호
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• pp.152-161
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• 2015

CodY is a highly conserved protein in low G+C gram-positive bacteria that regulates genes involved in sporulation and stationary-phase adaptation. Bacillus thuringiensis is a grampositive bacterium that forms spores and parasporal crystals during the stationary phase. To our knowledge, the regulatory mechanism of CodY in B. thuringiensis is unknown. To study the function of CodY protein in B. thuringiensis, BMB171codY^- was constructed in a BMB171 strain. A shuttle vector containing the ORF of cry1Ac10 was transformed into BMB171 and BMB171codY^-, named BMB171cry1Ac and BMB171codY^-cry1Ac, respectively. Some morphological and physiological changes of codY mutant BMB171codY^-cry1Ac were observed. A comparative proteomic analysis was conducted for both BMB171codY^-cry1Ac and BMB171cry1Ac through two-dimensional gel electrophoresis and MALDI-TOF-MS/MS analysis. The results showed that the proteins regulated by CodY are involved in microbial metabolism, including branched-chain amino acid metabolism, carbohydrate metabolism, fatty acid metabolism, and energy metabolism. Furthermore, we found CodY to be involved in sporulation, biosynthesis of poly-β-hydroxybutyrate, growth, genetic competence, and translation. According to the analysis of differentially expressed proteins, and physiological characterization of the codY mutant, we performed bacterial one-hybrid and electrophoretic mobility shift assay experiments and confirmed the direct regulation of genes by CodY, specifically those involved in metabolism of branched-chain amino acids, ribosomal recycling factor FRR, and the late competence protein ComER. Our data establish the foundation for in-depth study of the regulation of CodY in B. thuringiensis, and also offer a potential biocatalyst for functions of CodY in other bacteria.

• 정신신체의학
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• 제5권1호
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• pp.3-11
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• 1997

In becoming parents, the marital partners enter into a new developmental phase. The conception of the child is an act of mutual creativity during which the boundaries between the self and another were temporarily obliterated more completely than at any time since infancy. The infant is a physical fusion of the parents, and their personalities unite within the child. for many women, creativity as a mother becomes a central matter that provides meaning and balance to their lives. The husband usually has strong desires for an offspring and can be transformed by it. The child can profoundly affect one or both parents, and the influences are reciprocal-a child's needs or specific difficulties uncover a parent's inadequacy. following the child's development, each transition into a new developmental phase requires an adaptation by the parents, and one or another of these required adaptations may disturb a parent's equilibirium. And the personality changes, emotional difficulties, and regressions of a spouse that occur in response to some phase of parenthood can upset the marriage. Not only do children identify with parents, but parents also identify with their children. The parents take pleasure in child's joy and suffer with the child's pain more than in almost any other relationship. certain respects e parents lives again in the child. Through the process of identification the child can also provide one of the two parents with the opportunity to experience intimately the way in which a person of the opposite gender grows up. Parenthood also provides the opportunity to be loved, admired, and needed simply because one is a parent and, as such, a central and necessary object in the young child's life. The many potentialities for emotional satisfactions from parenthood manage to outweigh the tribulations and sacrifices that are required. The child also exerts an indirect effect through changing the parent's position in the society, for new sets of relationships are established as the parents are drawn to other couples with children of the same age, and for a new impetus toward economic and social mobility often possesses the parents. frequently the couple's relatedness to their own parents improves and grows firmer once again. Parenthood, the satisfactions it provides and the demands it makes, varies as life progresses : and changes with the parent's interests, needs, and age as well as with the children's maturation. There are phases in the child's life that the parents are reluctant to have pass, whereas they tolerate others largely through knowing that they will soon be over. The changing lives of the children provide many satisfactions that offset the tribulations, uncertainties, and regrets. The parents change. The young father, who was just starting on his carrier whom the first child was born, settles into a life pattern. He becomes secure with increasing achievement and interacts differently with the youngest child and provides a different model for him than for the oldest. The mother may have less time for a second or third child than for her first, but she may also be more assured in her handling of them. The birth of a baby when the parents art in their late thirties will find them Less capable of physical exertion with the child and less tolerant of annoyances, but they are less apt to be annoyed. Eventually the children min and leave home, but the couple do not cease to be parents.

• Asia pacific journal of information systems
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• 제20권1호
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• pp.33-56
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• 2010

The current business environment has been characterized as less munificent, highly uncertain and constantly evolving. In this environment, the company with dynamic capability is reported to be more successful than others in building competitive advantage. Dynamic capability focuses on the link between a dynamically changing environment, strategic agility, architectural reconfiguration, and value creation. Being characterized to be flexible and adaptive to market circumstance changes, an organization with dynamic capability is described to have high resource fluidity, which represents business process, resource allocation, human resource management and incentives that make business transformation faster and easier. Successful redeployment of the resources for dynamic adaptation requires organizational forms and reward systems to be well aligned with firm's technological infrastructures and business process. The alignment is considered to be an executive level commitment. Building dynamic capability is knowledge driven; relying on new knowledge to reconfigure firm's resources. Past studies established the link between the effective execution of a knowledge-focused strategy and relevant setting of architectural elements such as human resources, structure, process and information systems. They do not, however, describe in detail the underlying processes by which architectural elements are adjusted in coordinated manners to build knowledge-driven dynamic capability. In fact, understandings of these processes are one of the top issues in IT management. This study analyzed how a Korean corporation with a knowledge-focused strategy aligned its architectural elements to develop the dynamic capability and thus create value in the dynamically changing markets. When the Korean economy was in crisis, the company implemented a knowledge-focused strategy, restructured the organization's architecture by which human and knowledge resources are identified, structured, integrated and coordinated to identify and seize market opportunity. Specifically, the following architectural elements were reconfigured: human resource, decision rights, reward and evaluation systems, process, and IT infrastructure. As indicated by sales growth, the reconfiguration helped the company create value under an extremely turbulent environment. According to Ancona et al. (2001), depending on the types of lenses the organization uses, different types of architecture will emerge. For example, if an organization uses political lenses focusing on power, influence, and conflict. the architecture that leverage power and negotiate across multiple interest groups would emerge. Similarly, if an organization uses economic lenses focusing on the rational behavior of organizational actors making choices based on the costs and benefits of action, organizational architecture should be designed to motivate and provide incentives for the actors (Smith, 2001). Compared to this view, information processing perspectives consider architecture to be designed to maximize the capacity of information processing by the actors. Using knowledge lenses, the company studied in this research established architectural elements in a manner that allows the firm to effectively structure knowledge resources to form dynamic capability. This study is revelatory single case with a historic perspective. As a result of this study, a set of propositions and a framework are derived, which can be used for architectural alignment.

• 한국심리학회지:학교
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• 제9권3호
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• pp.485-503
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• 2012

본 연구의 목적은 학업수행과 성취결과에 주요한 예측변인 중 하나인 학업참여(academic engagement)를 측정하는 UWES-S(Utrecht Work Engagement Scale-Student)(Schaufeli et al., 2002a; 2002b) 척도를 타당화 하고, 학업참여와 학업동기 및 학업 만족도 간의 구조적인 관계를 파악하는 것이다. 본 연구의 타당화 표본은 우리나라 대학생들로써, 예비검사 285명, 본검사 366명으로 구성되었고, 그 절차는 다음과 같다. 첫째, UWES-S의 17개 문항에 대한 기술통계치 검토 및 척도의 요인구조 탐색을 위한 탐색적 요인분석을 실시하였다. 둘째, 문항의 심리측정학적 특성을 검토하기 위하여 등급반응모형에 기반한 문항 특성치를 추정하였다. 셋째, 척도의 내적타당도를 검증하기 위해 확인적 요인분석이 실시되었으며, 외적 타당도 확보를 위해서는 학업동기 및 학업만족 변인을 포함한 구조방정식 모형이 활용되었다. 이에 따른 연구결과는 다음과 같다. 첫째, 예비검사의 자료를 활용한 기술통계치 검토 및 탐색적 요인분석 결과 3요인 구조가 지지되었으며, 4개의 문항이 제거된 최종 13개 문항이 제안되었다. 둘째, 등급반응모형에 의해서 추정된 문항 특성치들을 검토한 결과, 최종 문항의 양호도는 수용 가능한 수준이었고, 또한 학업참여 척도의 3요인 모형(열정, 헌신, 몰두)은 자료에 잘 부합하는 것으로 나타났다. 또한 외적타당도 검증 결과, 학업참여는 학업동기와 학업만족을 부분매개 하는 것으로 나타났다. 마지막으로 본 연구에서 타당화 된 대학생용 UWES-S와 기존에 타당화 된 고등학생용 UWES-S(추헌택, 손원숙, 2011)와의 차이점을 논의하고, 표본별 학업참여 구인의 동등성 검증의 필요성 및 추후 척도 타당화 연구를 위한 제언을 포함하였다.