• 제목/요약/키워드: Adaptation in College

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고지방식이를 급여한 마우스의 간과 HepG2 세포에서 TJGB의 효과에 대한 연구 (Effect of TJGB on the liver of high-fat diet-fed mice and the viability of HepG2 cells)

  • 김희영;박예진;안효진
    • 대한융합한의학회지
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    • 제5권1호
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    • pp.55-60
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    • 2023
  • Objectives: This study was performed to investigate the effect of TJGB on the liver of high-fat diet (HFD)-fed mice and the cell viability of HepG2 cells. Methods: After a week adaptation, 8-week-old C57BL/6N mice were fed with a 45% HFD or normal diet for 3 weeks. For the next 9 weeks, the mice were divided into 6 groups: normal diet group; HFD group; HFD plus orlistat group; HFD plus Ephedra sinica Stapf (ES) group; HFD plus low dose of TJGB group; HFD plus high dose of TJGB group. To estimate the effect of TJGB in the liver of HFD-fed mice, the protein expressions of phospho-acetyl-CoA carboxylase (p-ACC) and liver X Receptor (LXR) were determined by Western blot assay. The cell viability of ES and TJG was also evaluated in HepG2 cells. Results: The administration of TJGB had little effect on the protein expressions of p-ACC and LXR in the liver of HFD-fed mice. And the cytotoxicity was showed above 7.8 ㎍/mL in HepG2 cells. Conclusion: Further research is needed to evaluate the mechanism of TJGB on hepatic steatosis and cytotoxicity in HepG2 cells.

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조직 내 정보시스템의 양면적 사용 (Ambidextrous Use of Information Systems in an Organization)

  • 강현정;김미희
    • 경영정보학연구
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    • 제22권1호
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    • pp.167-182
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    • 2020
  • 조직의 양면성은 일반적으로 경쟁적 시장에서 생존하기 위해 중요한 조직적 혁신을 가능하게 하는 유연성으로 해석된다. 정보시스템 사용자의 탐색적 혹은 활용적 사용의 양면성이 역동적 혹은 운영적 작업 간에 유연한 전환을 가능하게 하여 결과적으로 작업성과를 높이는 데 기여하게 된다. 본 연구는 개인 수준에서의 정보시스템 사용 양면성의 보완적 적합성이 업무 성과를 향상시키는지 검증하고자 하였다. 나아가 이 둘이 양면적 사용에서 차지하는 비중에 따라 업무의 유형에 따른 성과에 기여하는지도 알아보았다. 다항적 회귀분석과 표면분석을 통해 정보시스템 사용 패턴의 부조화적 적합성의 효과를 확인하였다. 이를 확산적 양면성과 수렴적 양면성으로 분류하고 각 패턴의 효과는 작업의 역동적 혹은 운영적 유형에 따라 다르게 나타남을 확인하였다.

제이륜국제성공(第二轮国际成功): 일개안례연구(一个案例研究) (International Success the Second Time Around: A Case Study)

  • Colley, Mary Catherine;Gatlin, Brandie
    • 마케팅과학연구
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    • 제20권2호
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    • pp.173-178
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    • 2010
  • 这是一家私人, 第三代家族拥有的公司, Boom Technologies 公司(BTI). 对电力设施提供产品和服务的供应商, 通信和承包商的市场,不断进步的出口. 尽管在2008年出口销售只占总收入的5%, BTI已形成了一个完整的出口部门. 他们的出口部门的执行董事揭示了一家私营公司的试验和错误以及他们对成功的海外市场的疑问. 自成立以来, BTI始终相信它最大的资产是它的雇员. 当出口销售因为缺乏战略和方向而挣扎时, BTI为其出口部门雇了一位董事总经理. 在BTI总裁和总经理的领导下, 他们很好的利用了这个部门的技能和知识. 为向海外扩展他们的市场份额, 增加出口销售他们进行了机构调整. 结果就是, 出口销售增加了4倍, 国家的地区经理增加了, 同时成功养成了分销渠道网络. 有时, 由于公司的结构, 收入形成很难决定. 因此, 在1996年, 出口部门重组为有限责任公司. 这使得公司改进收入和费用. 最初, 80%的BTI出口销售来自两个国家;因此,最初在海外出售的方法并没有达到预期目标. 然而, 所做的修改, 使得现在公司 经营, 销售超过80个国家. 总经理指出主要有三个出口扩张挑战 1. 产品和船运—BTI主要障碍是产品装配. 最初, 大多数的产品被聚集在美国, 这增加了运输包装费用. 有这么多的部分指定订购, 很多次定的东西到的时候有些零部件都丢失了. 失踪的零件价值上万美元. 装运这些失踪的部分也花费成千上万的美元, 外加一个延迟交货时间六到八周, 所有的费用都由BTI出. 2. 产品适应—在BTI80个出口国家中, 每个国家的安全, 产品标准都不同. 重量, 特殊证, 产品的规格要求, 测量系统的稳定性, 卡车都会因国别而不同. 作为一种准入障碍,以致很难使产品适应. 技术和安全标准的障碍, 作为一种保护国内产业的方法, 可以阻碍成功的进入外国市场 3. 市场的挑战—分销的重要性给BTI带来了很多挑战,因为他们试图根据他们的分销系统来确定每个国家如何操作. 有些国家已经从一个小的竞争对手, 只生产一种具有竞争力的产品而极具竞争力. 而BTI制造超过100种的产品. 营销资料是另一个BTI所关心的, 因为他们试图对经销商推动销售成本. 从翻译和文化差异的角度, 合适的市场营销资料可能会花费很多. 此外, 美国的纸张大小不同于别的一些国家, 当试图复制相同的布局和设计时, 就会出现许多问题. 分销已经成为BTI所面临的挑战之一, 公司宣称他们的分销网络是他们的竞争优势之一, 因为他们的分销商的位置和名字都是保密的. 另外, BTI每年有两次奉献: 培训分销商一年, 另一个是分销商会议. 产品, 航运, 产品适应性, 营销这些挑战,这些海外市场错综复杂需要时间和耐心. 另一个竞争优势是BTI的摇篮到坟墓的策略, 他们遵循产品销售到它的最终安息地, 无论卡车是出租或购买新的或用过的. 他们对该公司购买或租赁之前的产品都提供服务和设备维护计划和一份详细的费用分析. 扩大海外总是会面临挑战. 如总经理说, "如果你没有耐心(出口业务), 你最好做别的事." 知道如何快速适应提供必要的技能, 适应每个国家的不同需求, 以及独特的挑战, 使他们能够保持竞争力.

사상체질별 식이 섭생이 건강에 미치는 영향 -한방건강증진센터 시범운영을 위한 기초연구- (Effect of Diet Regimen of Sasang Constitution on Health Status)

  • 김귀분;조결자;이향련;신혜숙;김광주;문희자;김윤희;강현숙;박신애;지은선
    • 동서간호학연구지
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    • 제7권1호
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    • pp.18-31
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    • 2002
  • This study, as a basic research to manage a Chinese Medicine Health Promotion Center by way of showing an example, is a before and after experiment research for simple group to verify a difference with cholesterol, health status and perception of health in order to confirm a effectiveness of diet and regimen according to the 4th status of physical constitution. Research object was chosen of 42 persons who operate a physical constitutional dietary regimen among them after selecting professors and clinical nurses (55 persons) majoring in the science of nursing who participated in Chinese Medicine-oriented Nurse Training Course from Aug. of 2001 to Feb. of 2002 all over the country. Diagnostic tools for physical constitution was used of the questionary that is currently consisted of physical constitution grouping test in Eastern & Western Diagnose Center of K Medical Center, and rating of health status was used of the tool that standardized CMI(Cornell Medical Index) to be available for Korean, and perception measurement for health status was used of a visual analogue scale for the health status that each one perceive personally, and physiological status was measured of cholesterol in blood. Analysis for the collected data was carried out by percentage, $X^2$ test, paired t-test according to research object by using SPSS, and the results of this study are as follows. 1) There was no difference with cholesterol before or after the experiment for objects. As a result of estimation about difference with health status by areas before or after the experiment, there are more improved result in eyes, ears, digestive organs, bones and sinews organs, frequency of a disorder, habit, adaptation status, angry, healthy status than before the experiment. As a whole, after the experiment the health was more improved than before the experiment. As the result to inspect a difference of health perception between before and after experiment, after the experiment the health perception level was improved than before, however there was no meaningful differences. 2) As the result to inspect a difference of cholesterol between before and after experiment according to object's physical constitution, in the case of So-yang-in(a person with the minimum male: according to the male and female principles(the sun and the moon)) among the 4th status of physical constitution there was only meaningful difference statistically, however, after the experiment their cholesterol's value was increased. As the result to inspect the difference of health status between before and after the experiment according to physical constitution, all of Ta-um-in(a person with maximum the female), So-yang-in(with the minimum male), So-um-in(with the minimum female) had a meaningful difference before and after the experiment, which means that in all case by physical constitutional groups, after the experiment their health status was more improved than before the experiment. As the result to inspect a difference of health perception between before and after according to physical constitutions, in the case of Tae-um-in and So-um-in, average score after the experiment was risen than before the experiment so that it means that the level of health perception was improved, however, there was no meaning statistically. According to the above results, if continuous diet and regimen by each physical constitutions could be implemented, it is certain that the health could be maintained and promoted. And, what we are healthy is for oneself to feel it subjectively. However, I think that cholesterol score in blood that we can view objectively could be changed distinctly if we can implement a strict diet and regimen. Accordingly, it is necessary for a method and period of experiment to be more strict and longer. According to the above results, I would like to suggest as follows. 1) In order to understand health status by Korean's physical constitutions and to generalize it, these research will be repeated against much more objects that could be selected by proper grouping method to consider a representative. 2) It is necessary for a research to inspect health status by physical constitution by developing a health status measurement tool that has higher confidence and propriety based on physical constitutional theory.

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Effects of Dietary Supplementation of Magnesium Hydrogen Phosphate (MgHPO4) as an Alternative Phosphorus Source on Growth and Feed Utilization of Juvenile Far Eastern Catfish (Silurus asotus)

  • Yoon, Tae-Hyun;Lee, Dong-Hoon;Won, Seung-Gun;Ra, Chang-Six;Kim, Jeong-Dae
    • Asian-Australasian Journal of Animal Sciences
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    • 제27권8호
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    • pp.1141-1149
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    • 2014
  • The present study was conducted to investigate a supplemental effect of magnesium hydrogen phosphate (MHP, $MgHPO_4$) as an alternative phosphorus (P) source on growth and feed utilization of juvenile far eastern catfish (Silurus asotus) in comparison with three conventional P additives (monocalcium phosphate (MCP), dicalcium phosphate (DCP) and tricalcium phosphate [TCP]) as positive controls. A basal diet as a negative control was prepared without P supplementation and four supplemental P sources were added at the level of 2%. Five groups of 450 fish having mean body weight of 11.3 g following 24 h fasting after three week adaptation period were randomly distributed into each of 15 tanks (30 fish/tank). Fish were hand-fed to apparent satiety twice a day for 8 weeks. Fish fed MHP had weight gain (WG), protein efficiency ratio and specific growth rate comparable to those fed MCP. Fish fed MHP and MCP had feed efficiency (FE) significantly higher (p<0.05) than those fed DCP. Fish groups fed control and TCP showed the lower FE than the other groups which was significantly different (p<0.05) from those of fish fed the other diets. Survival rate was not significantly different (p>0.05) among treatments. Fish fed control had the lowest hematocrit, which was significantly different (p<0.05) from that of fish fed MHP. Fish fed MCP and MHP had plasma P higher (p<0.05) than fish fed the other diets. Relative efficiencies of MCP, DCP and TCP to MHP were found to be 100.5 and 101.3%, 92.0 and 91.6%, and 79.1 and 80.9% for WG and FE, respectively. P availability was determined to be 88.1%, 75.2%, 8.7%, and 90.9% for MCP, DCP, TCP, and MHP, respectively. Consequently, MHP recovered from wastewater stream showed that as an alternative P source its performance was comparative with MCP on growth and feed utilization of juvenile far eastern catfish.

대학생기독교선교회 시니어간사의 경력전환 경험 탐색 (Exploring the Meanings of Career Transition Experience of Senior Stewards of the Campus Crusade for Christ)

  • 신봉진;유기웅
    • 한국콘텐츠학회논문지
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    • 제18권10호
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    • pp.247-256
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    • 2018
  • 본 연구는 세속 직업에 종사하다가 대학생 선교단체 간사로 경력을 전환한 대학생 선교단체 간사의 경력전환 과정과 경험을 탐색하는 것을 목적으로 한다. 연구목적을 달성하기 위하여 한국대학생선교회(CCC)에 소속되어 있는 시니어간사 5명을 인터뷰하여 분석하였다. 주요 연구결과는 다음과 같다. 첫째, 대학생 기독선교회 시니어 간사의 경력전환 동기는 소명의식과 유관함을 알 수 있다. 둘째, 경력전환 과정에서 새로운 환경에 대한 적응과 주위로 부터의 격려와 지지를 경험하는 것으로 나타났다. 셋째, 간사의 경력전환의 의미는 하고자 했던 일을 다시 찾게 됨과 약속지킴, 특별하고 영광스러운 삶인 것으로 나타났다. 이상의 연구결과를 토대로 다음과 같은 결론을 얻었다. 첫째, 선교단체 간사의 소명실행은 소명확인의 단계가 필수적임을 확인할 수 있었다. 둘째, 선교단체 간사의 소명실행은 주위 지지자들이 있을 때 더욱 지속됨을 알 수 있었다. 셋째, 선교단체 간사의 경력전환경험이 갖는 의미는 소명을 따라가는 삶에 있음을 알 수 있었다.

관광유형다변화에 따른 문화해설사양성에 대한 제언 (A Study on the Cultural Interpreters and Muti-phased Tourism)

  • 이승재
    • 디지털융복합연구
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    • 제12권4호
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    • pp.467-474
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    • 2014
  • 21세기 관광과 문화의 중심지로 부상되고 있는 아시아 지역은 서구인들의 눈에 신비와 호기심의 대상이다. 오천년 이상의 역사를 간직하고 있는 한반도는 어디를 가나 역사와 문화가 숨쉬고 있다. 이러한 역사와 문화가 서구인에게 노출되면서, 단순히 눈의 즐거움을 제공할 뿐 아니라 지적 호기심을 충족시킬 수 있는 대안 마련이 시급하다. 정부에서도 관광객의 높아진 수준과 지적요구를 충족시키기 위해 다양한 문화 관광상품을 기획하고 있으며, 더불어 문화해설사를 제도적으로 도입하여 국내수요를 중심으로 확산시키고 있다. 본 연구는 문화유적지에서 해설사의 역할과 관광지 언어전문가인 가이드의 관계를 Cohen의 가이드 역할틀을 중심으로 확장된 가이드 커뮤니케이션틀 (이승재 2011)에 근거하여 살펴보고, 다양화 전문화되고 있는 외래관광객의 성향변화를 외래어 문화해설사 역할로 수렴하여 이를 가이드 역할전문화의 일환으로서 설명하고자 한다. 또한 전통문화유산을 전승하고 발전시키기 위해 문화해설사 및 외국어 문화해설사의 전문적인 양성을 제언하면서, 이를 위해 국내에 체류하는 다문화가정과 외국인 유학생을 외래어 문화해설사로 양성하여 한국문화의 전령사로 적극적으로 활용할 것을 제안하고자 한다.

여성결혼이민자가 경험하는 다문화가족 적응에 관한 연구 -T시를 중심으로- (A Study on the interracially Married Female Immigrant's Adaptation of Multi-cultural Families : Qualitative Methods)

  • 한상영
    • 한국산학기술학회논문지
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    • 제13권11호
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    • pp.5066-5075
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    • 2012
  • 본 연구는 한국에 여성결혼이민자가 경험하는 다문화가족 적응 형태를 그들의 입장에서 바라봄으로써 보다 질적이고 개별적인 간호중재 전략을 개발하는 기틀을 제공하고자 하는데 있다. 연구문제는 "여성결혼이민자의 자녀양육은 어떻게 이루어지고 있는가?"이다. 연구참여자는 여성결혼이민자 총 13명이다. 연구방법은 관찰과 심층면접, 상담, 그리고 주변 인물들을 통한 비공식적인 대화를 통해 자료를 수집하여 Spradley(1990)의 문화기술지 방법론을 적용한 질적 연구로 서술하였다. 결론적으로는 여성결혼이민자에서의 양육경험을 통해 다문화가정 어머니에게는 '의사소통의 장애', '열약한 양육환경', '이질적인 문화', '양육책임의 떠맡음', '고국가족에 대한 그리움', '미래에 대한 걱정'으로 나타났다. 다문화가정 가족에게는 '수치감', '양육의 무관심'으로 나타났다. 자녀에게는 '외톨이', '언어발달의 장애', '학습능력의 부족', '영양불량', '문제행동'이 나타났다. 다문화가정 어머니와 가족의 공통적인 요소에는 '다문화 이해부족', '의사소통 단절', '종속관계', '신뢰감부족'으로 나타났다. 다문화가정 어머니와 자녀의 공통적인 요소에는 '외모의 차이', '가족 사회적 차별'로 나타났다. 가족과 자녀의 공통적인 요소에는 '양육 참여 부족', '놀아주지 않음'으로 나타났다. 다문화가정 어머니와 가족, 그리고 자녀에 나타나는 공통적인 요소는 '사회적 편견', '불안정한 가족분위기', '저소득', '한국인으로 뿌리내리기'로 나타났다.

한국 남부지방 난온대성 상록활엽수의 동해피해 -전라남도 광양시 중마동의 후박나무를 중심으로- (Freezing Injury of Evergreen Broad-Leaved Trees in Warm-Temperature in the Southern Region in Korea -A Case of Machilus Thunbergii Siebold & Zucc. on the Jungma-dong, Gwangyang-city, Jeollanam Province-)

  • 이기원;김도균
    • 한국환경복원기술학회지
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    • 제20권1호
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    • pp.77-96
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    • 2017
  • This study was carried out to clarify the climatic factors of the freezing injury for the judgement on the adaptation areas of evergreen broad-leaved trees. We surveyed and analyzed the climatic factors of the freezing injury to Machilus thunbergii Siebold & Zucc. on the streets with the analyzation of planting grounds, soil conditions and the surrounding buildings. This study showed that only the minimum air temperature factor out of the other climate elements, which were the annual precipitation; the average annual temperature; the average monthly temperature of january; the average monthly minimum temperature of January; the average temperature of the coldest month; the warmth index and the coldness index, was matched up with the previous theories and reports on the freezing damages on the evergreen broad leaved trees and Machilus thunbergii Siebold & Zucc. The freezing injury of Machilus thunbergii Siebold & Zucc was occurred when the mean minimum temperature of the coldest month(TMC) in winter season fell down below $-4.1^{\circ}C$ and the temperature fell down below $-9.2^{\circ}C$. The freezing damage on Machilus thunbergii Siebold & Zucc surrounded by high buildings were less than those surrounded by low buildings or at non buildings.

음악요법이 근골격계 외상환자의 통증 및 우울에 미치는 영향 (Effects of Music Therapy on Pain and Depression of Musculoskeletal Trauma Patients)

  • 김정애
    • 근관절건강학회지
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    • 제1권1호
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    • pp.48-70
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    • 1994
  • The purpose of this study was to determine the effects of music therapy on acute, subacute and chronic pain and depression of musculoskeletal trauma patients. The study was designed using nonequivalent control group pretest-posttest design within the framework of an adaptation model. The subjects were composed of forty patients, and twenty of them were assigned to the experimental group and twenty to the control group within the unit of patients. Data were summarized as follows : 1. There were significant changes of pain scores in an experimental and a control group measured before and after the treatment. 2. There were significant changes of pulse rates, respiration rates and systolic blood pressure, but were no significant changes of diastolic blood pressure in an experimental and a control group measured before and after the treatment. 3. There were no significant changes of the amount of ${\beta}$-endorphin in an experimental and a control group measured before and after the treatment. 4. There were no significant changes of depression scores in an experimental and a control group measured before and after the treatment. As a result, music therapy was a useful nursing intervention for relief of acute, subacute and chronic pain. Two suggestions could be made on the ground of the results of this study. 1. On the basis of endogenous pain control theory, it's necessary to research the changes of the amount of ${\beta}$-endorphin as the effect of the music therapy on patients having severe pain. 2. It's necessary to research the changes of the amount of ${\beta}$-endorphin according to the lapse of time after the music therapy for pain relief.

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