• Journal of the Korean Institute of Oriental Medical Informatics
• /
• v.11 no.2
• /
• pp.57-64
• /
• 2005

Objectives The aim of this study is to evaluate effects of hard board applied to acute low back pain patient by using Visual Analogue Scale(VAS) and Pain Rating Score(PRS). Methods From March. 2005 to October. 2005, 20 cases of acute low back pain were divided into 2 groups in sequence. Control group took a rest on the bed(marble-sponge mattress) and sample group took a rest on the hard board. Visual Analogue Scale(VAS) and Pain Rating Score(PRS) were used to assess the change of pain. VAS and PRS were checked 3 times before the treatment, after 3day treatment and 6day treatment. Results 1. After 3day and 6day treatment, there was statistical significance between control and sample group by VAS. 2. After 3day and 6day treatment, there was statistical significance between control and sample group by PRS. Conclusions On treating acute low back pain, it is more effective taking a rest on the hard board than taking a rest on the bed. Further study is needed about effects of hard board applied to acute low back pain patient.

• Korean Journal of Acupuncture
• /
• v.26 no.2
• /
• pp.75-89
• /
• 2009

Objectives: Warm needling combines simultaneously the effects of acupuncture and moxibustion. This study was to investigate whether warm needling could relieve acute knee arthritis induced by carrageenan in rats. Methods: To illuminate the underlying mechanisms of the warm needling-induced antinociception, weight bearing force (WBF) was observed on the acute knee arthritic rat model. Under general anesthesia, ST36, SP9, Hakjung extra point, LI4 were punctured and stimulated with 30 mg moxa ball combustion on top of the needle (${\emptyset}0.18{\times}8mm$). Results: In behavioral test, rats subsequently showed a reduced stepping force of the affected limb 3 hours after the induction of arthritis. Warm needling on the contralateral or ipsilateral ST36 failed to show antinociceptive effect on the acute knee arthritis. Warm needling on the contralateral SP9 or LI4 increased WBF values to normal level in the acute stage of the arthritis. Warm needling on the Hakjung extra-point resulted in the significant antinociceptive effects through acute stage. These effects of warm needling were suppressed by opioids receptor antagonist naltrexone (10 mg/kg, i.p.) and alpha adrenoceptor antagonist phentolamine (5 mg/kg, i.p.). Conclusion: The data suggest that warm needling-induced antinociception is differently mediated by acupoints and accomplished by activating the descending inhibitory systems including endogenous opioids and $\alpha$-adrenoceptors.

• Journal of Pharmacopuncture
• /
• v.15 no.1
• /
• pp.12-17
• /
• 2012

Objectives: This study was designed to investigate the protective effects of Atractylodis Rhizoma pharmacopuncture (ARP) against acute gastric mucosal lesions induced by compound 48/80 in rats. Methods: The ARP was injected in Joksamni (ST36) and Jungwan (CV12) 1 hr before treatment with compound 48/80. The animals were sacrificed under anesthesia 3 hrs after treatment with compound 48/80. The stomachs were removed, and the amounts of gastric adherent mucus, gastric mucosal hexosamine, thiobarbituric acid reactive substances (TBARS), xanthine oxidase (XO), and superoxide dismutase (SOD) were measured. Also, histological examination were performed. Results: Gastric adherent mucus, gastric mucosal hexosamine and histological defects of gastric mucosa declined significantly after ARP treatment. Changes in gastric mucosal TBARS were also reduced by ARP treatment, but this result was not statistically significant. ARP treatment did not change the XO and the SOD activities. Conclusions: ARP showed protective effects for acute gastric mucosal lesions induced by compound 48/80 in rats. These results suggest that ARP may have protective effects for gastritis.

• Journal of Sasang Constitutional Medicine
• /
• v.17 no.3
• /
• pp.103-112
• /
• 2005

1. Objective : The present author have examined the comparative effects of Hyeongbangjihwang-tang and Sibimikwanjung-tang in glycerol-induced acute renal failure, a model for myoglobinuric acute renal failure. 2. Methods : Above two prescriptions were applied to rat ad libitum and serum level of creatinine, glucose and blood urea nitrogen(BUN) were measured. And serum level of $Na^+$, $K^+$ and $Cl^-$, too. 50%(vol/vol) glycerol at a dose of 10 ml/kg of rat body weight intramuscularly and 1% concentration of prescriptions were applied to rats for 7 days ad libitum. 3. Results : Serum level of creatinine and $K^+$ significantly increased by glycerol injection, and these showed pre-renal and renal cause of acute renal failure. Hyeongbangjihwang-tang administered group showed decreasing tendency on serum level of creatinine when compared with control groups, but not significant. Sibimikwanjung-tang administered group showed significant increase of serum level of BUN when compared with control groups. 4. Conclusions : Above two prescriptions showed no significant changes on glycerol induced acute renal failure, but Hyeongbangjihwang-tang and Sibimikwanjung-tang showed a little different manner of response.

• The Plant Pathology Journal
• /
• v.16 no.1
• /
• pp.19-24
• /
• 2000

The direct effects of acute $\textrm{O}_3$ on the growth, sporulation and infection of Pyricularia grisea, rece blast pathogen, were investigated to understand the interactions between ozone and the pathogen. Acute exposure of 200 nl $\textrm{l}^{-1}$ ozone for 8 h significantly reduced conidia germination on water atar. Ozone exposure of 200 nl $\textrm{l}^{-1}$ for 8h per day for 5 days had no effect on increase in colony diameter, but severely damaged actively growing aerial mycelia. However, the damage to mycalia was recovered during the following 16 h exposure of unpolluted air. Conidial production was also stimulated by the acute ozone exposure for 5 days. The conidia exposed to the acute ozone for 5 days normally germinates but slightly reduce appressoria formation on rice leaf. However, the conidia produced by artificial stimulation under the same ozone concentration for 10 days showed significant reduction in appressorea for mation on a hydrophobic film. This study suggests that the acute ozone could ingibit appressoria formation as well as vegetative growth of the pathogen, resulting in decrease in rece blast development in the field during summer when high ozone episodes could occur occasionally.

• Korean Journal of Pharmacognosy
• /
• v.15 no.4
• /
• pp.179-187
• /
• 1984

To investigate the recorded efficacy in Oriental medical references and effects in clinics, experimental studies were undertaken to estimate 'Palmiwhan' to the diuretic effect in normal rats, rabbits and rats with $HgCl_2-induced$ acute renal failure and hypotensive effects on the nephrogenous hypertension in rabbits with $HgCl_2-induced$ acute renal failure. The results of this study were summarized as follows; Increase in urinary volume, urinary $Na^+\;and\;Cl^-$ excretions were significantly recognized in normal rats and rabbits. Increase in urinary volume, urinary $Na^+\;and\;Cl^-$ excretions were significantly shown in rats with 2mg/kg $HgCl_2-induced$ acute renal failure. Although plasma electrolyte and creatinine levels were little affected, plasma urea nitrogen levels were significantly elevated in normal rats and 2mg/kg $HgCl_2-induced$ acute renal failure of rats. Although the blood pressure was not affected in normal rabbits and cats, hypotensive actions due to the diuretic effect were recognized in rabbits $HgCl_2-induced$ acute renal failure.

• Physical Therapy Korea
• /
• v.14 no.2
• /
• pp.76-84
• /
• 2007

This study was designed to determine the efficacy of ultrasound and laser therapy for sub-acute lower back pain. Twenty-seven patients with sub-acute low back pain were recruited, who were randomly assigned to three groups: Ultrasound group (actual ultrasound, 1.1 MHz, $1.0W/cm^2$, duty cycle 100%, 10 min/session, n=9), laser group (actual laser, 904 nm, 155 ns, 13.5 W, 12 mW, 90 sec/point, n=9), and control group (placebo ultrasound or placebo laser, n=9). All of treatments including placebo procedures were applied to patients over a period of 2 weeks, five times a week. Visual Analogue Scale (VAS), Modified Schober's Test (MST), and Modified Oswestry Disability Questionnaire (MODQ) were used by the clinical and functional evaluations before and after intervention. At post-hoc, significant differences were observed in all groups with respect to VAS, MST (p<.05), except MODQ. VAS and MST score were more significantly improved in the ultrasound group than the laser and control group (p<.0167). However, no significant difference was present between the laser group and the control group. Therefore, this study revealed that ultrasound therapy was effective in pain relief and improvement of lumbar mobility in patients with sub-acute lower back pain. However, laser therapy did not show the effects for sub-acute lower back pain.

• Korean Journal of Pharmacognosy
• /
• v.15 no.4
• /
• pp.199-202
• /
• 1984

The effects of 'Ssangkum-tang' on the acute gastritis and the gastric ulcer caused by acetic acid were studied. The water extract improved the inflammation of the acute gastritis and decreased the diameter of the ulcer area.

• Annals of Clinical Neurophysiology
• /
• v.10 no.2
• /
• pp.112-115
• /
• 2008

Colchicine is a drug used for the treatment of acute gouty arthritis or various autoimmune diseases. Gastrointestinal adverse effects such as abdominal pain and vomiting are the common side effects of the drug, but rarely myopathy has been reported to occur particularly in renal recipients who were treated concomitantly with immunosuppressants. Herein, we report a case who presented with acute myopathy after treated with colchicine for acute gouty arthritis.

• The Journal of Korean Academy of Orthopedic Manual Physical Therapy
• /
• v.18 no.1
• /
• pp.73-82
• /
• 2012

Background: The purpose of this study was to investigate the effects of modality, taping and joint mobilization for patients with acute whiplash-associated disorders. Methods: Joint mobilization technique and kinesio taping was done to the patients who diagnosed with acute whiplash-associated disorders due to traffic accidents. Results: We got the results that it is quite effective to increase cervical range of motion and decrease the pain, according to the results, present study was performed to assess the impact on the neck disability index and fatigability. Conclusion: Joint mobilization technique applied to a person and taping applied to the other person then both people increasing cervical range of motion and reducing pain for the treatment of patients with acute whiplash-associated disorders was effective.