• Journal of Acupuncture Research
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• v.23 no.5
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• pp.79-92
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• 2006

Acupuncture has acupoints to treat, prevent, and reduce disease and to recover health by meridian guidance and reflexion. In the oriental medicine, meridian and acupoints are the foundations of treatment. Therefore, in the clinical treatment, we have to decide the therapeutic methods, meridian, acupoints, acupoint place, and acupoint match according to the disease. This study was designed to investigate the combined effects of ST36, ST37, and ST39 using electroacupuncture in rats. The present study was conducted to see the effects produced by combined electro-acupuncture(EA) at ST36, ST37, and ST39 on small intestine transportation in rats. EA(2 Hz, 5mA, pulse duration 1 ms) was applied for 30 minutes at acupoints of ST36, ST37, and ST39. The results are as follows. Compared to other acupoint place matches, ST36(left)+ ST37(right), ST36(left)+ST39(right), and ST37(left)+ST39 (right) were more effective than ST36(right)+ST37(left), ST36 (right)+ST39(left), and ST37(right)+ST39(left) for small intestine transporation(+ means acupoint place match). In terms of acupoint placement, ST36(left), ST37(right), and ST39(right) were more effective than the other sides for small intestine transporation. The data suggests that we have to consider acupoint place and acupoint match for acupucture therapy.

• Korean Journal of Acupuncture
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• v.40 no.3
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• pp.128-133
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• 2023

Objectives : There are many variations in the ST36 acupoint location. The purpose of this article is to suggest a method of locating the ST36 acupoint. Methods : Based on the available research and the neuroanatomical characteristics of the underlying acupoint, we summarized the proper procedure for finding the ST36 acupoint. Results : ST36 is 3 B-cun inferior to ST35 and is vertically situated on the line that connects ST35 and ST41. The ST36 acupoint corresponds to the deep peroneal nerve, which is situated in the tibialis anterior muscle's back. The neurovascular bundles that are located on the interosseous membrane between the interosseous crests of the tibia and fibula include the deep peroneal nerve, anterior tibial artery, and anterior tibial vein. According to both classical and modern literature, this acupoint can be found horizontally between the two muscles, tibialis anterior and extensor digitorum longus. Conclusions : Based on a review of the literature and neuroanatomical features, we suggest that ST36 can be positioned horizontally between tibialis anterior and extensor digitorum longus. Additional imaging studies and clinical proof are required to determine ST36 acupoint.

• Korean Journal of Acupuncture
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• v.27 no.3
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• pp.97-108
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• 2010

Background : The location of acupoints on rat, which may differ from that of human body due to anatomical structure, is defined variously among researchers, which may cause the problem of low repeatability and objectivity. Design : The measurement of hind limb consist of measuring the distance between knee joint and tibia tubercle in order to set the knee joint as common criteria. Based on it, the three mostly referred location of ST36 were represented with the knee joint as a datum point and compared. The electroacupuncture stimulation was administrated after the abdominal pain was induced by acetic acid. And the analgesic activity of each ST36 acupoint was evaluated by measuring the number of writhing reflex, in order to observe the differences of treatment effect in accordance with the location of ST36 acupoints. Results : The result of measurement confirmed the differences in the acupoint location of ST36 among researchers. The writhing reflex test using the acetic acid-induced abdominal pain stimulated with electroacupuncture of 100Hz showed that there were statistically significant differences in the analgesic effect between control group and three ST36 groups (P<0.05). However there were no differences observed among three mostly referred location of ST36 acupoints (P>0.05). Conclusions : We recommend "the point located 6.5 mm below the knee joint at the anterior tibial muscle" as a standard ST36 acupoint location qualified by the WHO Standard Acupuncture Point Locations in 2008.

• Korean Journal of Acupuncture
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• v.20 no.1
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• pp.1-20
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• 2003

This study was examined for effects of acupuncture of Zusanli (ST36) on the abdominal thermography of health subject. The volunteers who participating in this study had taken rest for 20-30 mins in room temperature (23-$25^{\circ}C$) before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day. The thermography of abdomen including a below part of the chest was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co, Korea) by time interval of 15 minutes at 15 min before, just before and 15 min after, 30 min after and 45 min after acupuncture stimulation. Acupuncture was applied to the left ST36 acupoint for 30 mins. The results showed that acupuncture of ST36 significantly had more potencies of changes on all the of abdominal thermography than those of control group. Also, it was observed that the quantities of thermal changes following acupuncture of ST36 been increased significantly comparing that of control group at all the ROIs (region of interest). Observed the thermography classified by ROI, however, it was failed that acupuncture of ST36 could modulate the specific areas concerning to the abdominal pathway of Stomach Meridian. These results suggest that acupuncture of ST36 may modulate thermal distributions and changes of abdominal areas including the below of chest.

• Korean Journal of Acupuncture
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• v.19 no.2
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• pp.13-33
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• 2002

This study was examined for effects of acupuncture of Zusanli (ST36) on the facial thermography in health subjects. The volunteers who participating in this study had taken rest for 20 - 30 mins in room temperature (23-$25^{\circ}C$) before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day. The thermography of face was taken using Infra-Red Imaging System (IR 2000, MEDI-CORE Co., Korea) by time interval of 15 minutes at 15 min before, just before and 15 min after, 30 min after and 45 min after acupuncture stimulation. Acupuncture was applied to the left ST36 for 30 mins. The results showed that acupuncture of ST36 significantly decreased the temperature of all the areas of facial surface comparing to those of control group. Also, it was observed that the quantities of thermal changes following acupuncture of ST36 been increased significantly at the A1, A4, A6, A7 and A9 ROIs (region of interest) comparing that of control group. Observed the thermography classified by ROI, it was clear the fact that acupuncture of ST36 could modulate the specific areas concerning to the facial pathway of Stomach Meridian, because the thermal responses following acupuncture of ST36 were specific at the A1, A2, A5 and A9 ROIs, relatively. These results suggest that acupuncture of ST36 may modulate thermal distributions and changes of facial areas concerned with Stomach Meridian.

• Korean Journal of Acupuncture
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• v.20 no.3
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• pp.29-34
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• 2003

Objectives : The purpose of this study was to investigate the Effect of Acupuncture Chok-samni(ST36) on Skin temperature(ST), Galvanic skin response(GSR) and Heart rate(HR) in humans. ST36 is used in uneasiness, high fever, stroke, paralysis on oriental medicine. Methods : Subjects were 18 healthy oriental medical students volunteers(15male, 3female, mean age-28). Under sequence of ST36 acupuncture, the first group was observed ST, the second group was observed GSR and the third group was observed HR. Skin temperature was measured on Haegye acupoint(ST41) before and after acupuncture stimulation. Each test took 15minutes. This test was performed twice in order to increase the statistical authenticity. Results : Our result indicates that acupuncture stimulation of ST36 statistically decreased skin temperature on ST41. Also statistically decreased in HR. The change of GSR after ST36 acupuncture was decreased, but there is no statistical. Conclusions : These results suggested that acupuncture stimulation of ST 36 has effect on ST and HR in human body, and may be used by treatment as control the nerve system.

• Korean Journal of Acupuncture
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• v.23 no.1
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• pp.15-36
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• 2006

Objectives . The aim of this study was to examine the effect of electroacupuncture(EA) at the ST36 on normal humans by using power spectral analysis. Methods : EEG(Electroencephalogram) power spectral exhibits site-specific and state-related differences in specific frequency bands. In this study, power spectrum was used as a measure of complexity. 32 channel EEG study was carried out in 12 subjects (10 males; age=26.7 years old, 2females; age=28 years old). Results ; In ${\alpha}$ (alpha) band, the power values at Fp2, F7, F3, Fz, FTC1, FTC2, T3, C3, Cz, C4, TT1, TCP1, CP1, CP2,T5, P3, Pz, P4, Po1, Po2, O1, Oz,O2 channels(p<0.05) during the ST36-acupoint treatment were significantly increased. In ${\beta}$ (beta) band, the power values at Fp2, F7, F3, Fz, F4, F8, FTC1, FTC2, T3, C3, Cz, C4, TT1, TCP1, CP1, CP2, T5, P3, Pz, P4, Po1, Po2, O1, Oz, O2 channels(p<0.05) during the ST36-acupoint treatment were significantly decreased. In ${\delta}$ (delta) band, the power values at F7, Fz, T3, C3, TT1, TCP1, CP1, CP2, T5, P3, Pz,T6, Po1, PO2,O1, Oz, O2 channels(p<0.05) during the ST36-acupoint treatment were significantly decreased. In ${\theta}$(theta) band, the power values at F7, Fz, FTC1, T3, TCP1, CP2, TCP2, Po1, Po2 channels(p<0.05) during the ST36-acupoint treatment were significantly decreased. ${\alpha}$/${\beta}$ values at Cz, T5, O1, Oz, O2 channels during the ST36-acupoint treatment were increased. ${\beta}$/${\theta}$ values at Fpl, F7, F3, Fz, F4, F8, FTC1, FTC2, T3, C3, C4, T4, TT1, TCP1, TCP2, TT2, P3, P4, T6, Pol channels during the ST36-acupoint treatment were increased. Conclusions : This results suggest that Electroacupuncture at the ST36 mostly affects the charge on alpha(23 channels), beta(25 channels) bands.

• Korean Journal of Acupuncture
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• v.29 no.4
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• pp.604-615
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• 2012

Objectives : The aim of this study was to observe the effect of moxibustion at combined acupoints of ST36, BL21 and CV12 in rats with sex and age. Methods : This study measured small intestinal motility in rats. First, cauterize with moxa was applied 5 times to the ST36, BL21 and CV12 in rats classified by sex and age under enflurane anesthesia. And then same treatment is done to mached acupoints of ST36, BL21 and CV12. Results : In single acupoint groups, cauterizing with moxa on ST36 increased with 5, 7 weeks in female and all weeks in male. The BL21 group increased with 5, 6, 7 weeks in female, and only 5 weeks in male. The CV12 group showed increasing with 5, 6 weeks in female and only 7 weeks in male. In combined acupoints groups, the ST36+BL21 with 8 weeks in male, the ST36+CV12 with 5, 8 weeks in female and 5, 6, 8 weeks in male, the CV12+BL21 only with 5 weeks in female, the ST36+BL21+CV12 only with 5 weeks in female showed increasing, respectively. Conclusions : Although these differents according to the sex and age in rats do not have a established tendency, the results suggested that the effects of moxibustion are experimentally should be considered the sex and age of individual.

• Journal of Physiology & Pathology in Korean Medicine
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• v.25 no.4
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• pp.691-696
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• 2011

In order to the neuroprotective effect of electroacupuncture (EA), the present study examined the effects of electroacupuncture inacupoint ST36 (Stomach 36) on trimethyltin chloride (TMT)-induced cognitive impairments rat using the Morris water maze (MWM) task and immunohistochemistry staining. The rats were randomly divided into the following groups: naive rat (Normal), TMT injection rat (Control), TMT injection + EA treated rat inacupoint ST36 (ST36) and TMT injection + EA treated rat in non-acupoint, base of tail (Non-AC). Electroacupuncture (2Hz, 2mA, and 10 minutes)was applied either to the acupuncture point ST36 or the nonacupuncture point in the tail for the last 14 days. In the water maze test, the animals were trained to find a platform in a fixed position during 4d and then received 60s probe trial on the $5^{th}$ day following removal of platform from the pool. Rats with TMT injection showed impaired learning and memory of the tasks and treatment with EA in acupoint ST36 (P<0.05) produced a significant improvement in escape latency to find the platform after $2^{nd}$ day and retention trial in the Morris water maze. Consistent with behavioral data, treatment with EA in acupoint ST36 also significantly increased expression of Choline acetyltransferase (ChAT) and Acetylcholinesterase (AChE) immunoreactive neurons in the hippocampus compared to the Control group. These results demonstrated that EA in acupoint ST36 has a protective effect against TMT-induced neuronal and cognitive impairments. The present study suggests that EA in acupoint ST36 might be useful in the treatment of TMT-induced learning and memory deficit.

• Korean Journal of Acupuncture
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• v.20 no.1
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• pp.21-30
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• 2003

Objectives : The pain was induced on upper and lower incisor of the rat based on the theory of 'connections of upper incisor pain with stomach meridian and lower incisor pain with large intestine meridian'. Such acupoints as LI4 and ST36 were used for alleviation of upper and lower incisor pain. Methods : The digastric myogram (dEMG) was utilized for the pain measurement. Results : The ST36 acupuncture after induction of upper incisor pain was gradually decreased or increased the dEMG. The LI4 acupuncture after induction of upper incisor pain was gradually decreased the dEMG. The ST36+LI4 acupuncture after induction of upper incisor pain was gradually decreased the dEMG. We knew this thing which the ST36+LI4 acupuncture decreased the dEMG most greatly and kept long compared to ST36 acupuncture, LI4 acupuncture. Conclusions : Acupuncture treatment at the loci of not only ST36 acupuncture but LI4 acupuncture were relieved the upper incisor pain. It was well suitable to the theory 'connections of upper incisor pain with stomach meridian' that ST36 acupuncture decreased the upper incisor pain. But there was not to decrease the dEMG for the ST36 acupuncture. We are considered as tracing study continuously about ST36 acupuncture. It was not suitable to the theory 'connections of upper incisor pain with stomach meridian' that LI4 acupuncture decreased the upper incisor pain. These results was considered as the function by the characteristic of the LI4 acupoint.